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收藏Synergizing bioprinting and 3D cell culture to enhance tissue formation in printed synthetic constructs
Guenther, Daniel; Bergerbit, Cedric; Marsee, Ary; Vedaraman, Sitara; Moliner, Alba Pueyo; Bastard, Celine; Eelen, Guy; Nava, Jose Luis Gerardo; Dewerchin, Mieke; Carmeliet, Peter; Kramann, Rafael; Schneeberger, Kerstin; Spee, Bart; De Laporte, Laura 分享 收藏 Single-cell RNA sequencing of cystic fibrosis liver disease explants reveals endothelial complement activation囊性纤维化肝病外植体的单细胞RNA测序揭示了内皮补体激活Declercq, Mathias; Treps, Lucas; Geldhof, Vincent; Conchinha, Nadine V.; de Rooij, Laura P. M. H.; Subramanian, Abhishek; Feyeux, Magalie; Cotinat, Marine; Boeckx, Bram; Vinckier, Stefan; Dupont, Lieven; Vermeulen, Francois; Boon, Mieke; Proesmans, Marijke; Libbrecht, Louis; Pirenne, Jacques; Monbaliu, Diethard; Jochmans, Ina; Dewerchin, Mieke; Eelen, Guy; Roskams, Tania; Verleden, Stijn; Lambrechts, Diether; Carmeliet, Peter; Witters, Peter 分享 收藏 The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cellsde Zeeuw, Pauline; Treps, Lucas; Garcia-Caballero, Melissa; Harjes, Ulrike; Kalucka, Joanna; De Legher, Carla; Brepoels, Katleen; Peeters, Kristel; Vinckier, Stefan; Souffreau, Joris; Bouche, Ann; Taverna, Federico; Dehairs, Jonas; Talebi, Ali; Ghesquiere, Bart; Swinnen, Johan; Schoonjans, Luc; Eelen, Guy; Dewerchin, Mieke; Carmeliet, Peter 分享 收藏 COVID-19 plasma induces subcellular remodelling within the pulmonary microvascular endotheliumPassi, Rainha; Cholewa-Waclaw, Justyna; Wereski, Ryan; Bennett, Matthew; Veizades, Stefan; Berkeley, Bronwyn; Caporali, Andrea; Li, Ziwen; Rodor, Julie; Dewerchin, Mieke; Mills, Nicholas L.; Beqqali, Abdelaziz; Brittan, Mairi; Baker, Andrew H. 分享 收藏 Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells细胞内BAPTA直接抑制PFKFB3，从而阻碍mTORC1-driven Mcl-1翻译并杀死MCL-1-addicted癌细胞Sneyers, Flore; Kerkhofs, Martijn; Speelman-Rooms, Femke; Welkenhuyzen, Kirsten; La Rovere, Rita; Shemy, Ahmed; Voet, Arnout; Eelen, Guy; Dewerchin, Mieke; Tait, Stephen W. G.; Ghesquiere, Bart; Bootman, Martin D.; Bultynck, Geert 分享 收藏 Covid-19 Plasma Exposure Causes Transcriptional, Morphological, And Functional Changes Within The Pulmonary Microvascular EndotheliumPassi, Rainha; Cholewa-Waclaw, Justyna; Wereski, Ryan; Veizades, Stefan; Bennett, Matthew; Berkeley, Brownwyn; Solomonidis, Emmanouil G.; Caporali, Andrea; Li, Ziwen; Beqqali, Abdelaziz; Dewerchin, Mieke; Mills, Nicholas L.; Brittan, Mairi; Baker, Andrew H. 分享 收藏 分享 收藏 Prioritization and functional validation of target genes from single-cell transcriptomics studiesSokol, Liliana; Cuypers, Anne; Truong, Anh-Co K.; Bouche, Ann; Brepoels, Katleen; Souffreau, Joris; Rohlenova, Katerina; Vinckier, Stefan; Schoonjans, Luc; Eelen, Guy; Dewerchin, Mieke; de Rooij, Laura P. M. H.; Carmeliet, Peter 分享 收藏 Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3Jacquemin, P; Durviaux, SM; Jensen, J; Godfraind, C; Gradwohl, G; Guillemot, F; Madsen, OD; Carmeliet, P; Dewerchin, M; Collen, D; Rousseau, GG; Lemaigre, FP 分享 收藏 Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endotheliumRajantie, I; Ekman, N; Iljin, K; Arighi, E; Gunji, Y; Kaukonen, J; Palotie, A; Dewerchin, M; Carmeliet, P; Alitalo, K 分享 收藏 The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferationVan Eynde, A; Nuytten, M; Dewerchin, M; Schoonjans, L; Keppens, S; Beullens, M; Moons, L; Carmeliet, P; Stalmans, W; Bollen, M 分享 收藏 Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast单细胞图谱识别健康和恶性乳腺中的脂质加工和免疫调节内皮细胞Geldhof, Vincent; de Rooij, Laura P. M. H.; Sokol, Liliana; Amersfoort, Jacob; De Schepper, Maxim; Rohlenova, Katerina; Hoste, Griet; Vanderstichele, Adriaan; Delsupehe, Anne-Marie; Isnaldi, Edoardo; Dai, Naima; Taverna, Federico; Khan, Shawez; Truong, Anh-Co K.; Teuwen, Laure-Anne; Richard, Francois; Treps, Lucas; Smeets, Ann; Nevelsteen, Ines; Weynand, Birgit; Vinckier, Stefan; Schoonjans, Luc; Kalucka, Joanna; Desmedt, Christine; Neven, Patrick; Mazzone, Massimiliano; Floris, Giuseppe; Punie, Kevin; Dewerchin, Mieke; Eelen, Guy; Wildiers, Hans; Li, Xuri; Luo, Yonglun; Carmeliet, Peter 分享 收藏 A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds针对PFKFB3的高通量筛选活动确定了具有新型支架的潜在抑制剂Li, Jie; Zhou, Yan; Eelen, Guy; Zhou, Qing-tong; Feng, Wen-bo; Labroska, Viktorija; Ma, Fen-fen; Lu, Hui-ping; Dewerchin, Mieke; Carmeliet, Peter; Wang, Ming-wei; Yang, De-hua 分享 收藏 Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesisMece, Odeta; Houbaert, Diede; Sassano, Maria-Livia; Durre, Tania; Maes, Hannelore; Schaaf, Marco; More, Sanket; Ganne, Maarten; Garcia-Caballero, Melissa; Borri, Mila; Verhoeven, Jelle; Agrawal, Madhur; Jacobs, Kathryn; Bergers, Gabriele; Blacher, Silvia; Ghesquiere, Bart; Dewerchin, Mieke; Swinnen, Johan V.; Vinckier, Stefan; Soengas, Maria S.; Carmeliet, Peter; Noel, Agnes; Agostinis, Patrizia 分享 收藏 Mitochondrial respiration supports autophagy to provide stress resistance during quiescenceMagalhaes-Novais, Silvia; Blecha, Jan; Naraine, Ravindra; Mikesova, Jana; Abaffy, Pavel; Pecinova, Alena; Milosevic, Mirko; Bohuslavova, Romana; Prochazka, Jan; Khan, Shawez; Novotna, Eliska; Sindelka, Radek; Machan, Radek; Dewerchin, Mieke; Vlcak, Erik; Kalucka, Joanna; Stemberkova Hubackova, Sona; Benda, Ales; Goveia, Jermaine; Mracek, Tomas; Barinka, Cyril; Carmeliet, Peter; Neuzil, Jiri; Rohlenova, Katerina; Rohlena, Jakub 分享 收藏 Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsisVandewalle, Jolien; Timmermans, Steven; Paakinaho, Ville; Vancraeynest, Lies; Dewyse, Liza; Vanderhaeghen, Tineke; Wallaeys, Charlotte; Van Wyngene, Lise; Van Looveren, Kelly; Nuyttens, Louise; Eggermont, Melanie; Dewaele, Sylviane; Velho, Tiago R.; Moita, Luis F.; Weis, Sebastian; Sponholz, Christoph; van Grunsven, Leo A.; Dewerchin, Mieke; Carmeliet, Peter; De Bosscher, Karolien; Van de Voorde, Johan; Palvimo, Jorma J.; Libert, Claude 分享 收藏 Tumor vessel co-option probed by single-cell analysis通过单细胞分析探测肿瘤血管共同选择Teuwen, Laure-Anne; De Rooij, Laura P. M. H.; Cuypers, Anne; Rohlenova, Katerina; Dumas, Sebastien J.; Garcia-Caballero, Melissa; Meta, Elda; Amersfoort, Jacob; Taverna, Federico; Becker, Lisa M.; Veiga, Nuphar; Cantelmo, Anna Rita; Geldhof, Vincent; Conchinha, Nadine, V; Kalucka, Joanna; Treps, Lucas; Conradi, Lena-Christin; Khan, Shawez; Karakach, Tobias K.; Soenen, Stefaan; Vinckier, Stefan; Schoonjans, Luc; Eelen, Guy; Van Laere, Steven; Dewerchin, Mieke; Dirix, Luc; Mazzone, Massimiliano; Luo, Yonglun; Vermeulen, Peter; Carmeliet, Peter 分享 收藏 Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesisChong, Suet Yen; Zharkova, Olga; Yatim, Siti Maryam J. M.; Wang, Xiaoyuan; Lim, Xiong Chang; Huang, Chenyuan; Tan, Chia Yee; Jiang, Jianming; Ye, Lei; Tan, Michelle Siying; Angeli, Veronique; Versteeg, Henri H.; Dewerchin, Mieke; Carmeliet, Peter; Lam, Carolyn S. P.; Chan, Mark Y.; de Kleijn, Dominique P. V.; Wang, Jiong-Wei 分享 收藏 Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotypeDeclercq, Mathias; de Zeeuw, Pauline; Conchinha, Nadine, V; Geldhof, Vincent; Ramalho, Anabela S.; Garcia-Caballero, Melissa; Brepoels, Katleen; Ensinck, Marjolein; Carlon, Marianne S.; Bird, Matthew J.; Vinckier, Stefan; Proesmans, Marijke; Vermeulen, Francois; Dupont, Lieven; Ghesquiere, Bart; Dewerchin, Mieke; Carmeliet, Peter; Cassiman, David; Treps, Lucas; Eelen, Guy; Witters, Peter 分享 收藏 
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