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Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease 短回肠微绒毛长度表型与儿童克罗恩病从炎症性到复杂性疾病行为进展相关 Haberman, Yael; Braun, Tzipi; Karns, Rebekah; Bartel, Courtney A.; Bonkowski, Erin; Simpson, Katherine F.; Walters, Thomas D.; Hyams, Jeffrey S.; Liu, Ta-Chiang; Kugathasan, Subra; Denson, Lee A.; VanDussen, Kelli L. 分享 收藏
Toward eliminating missed important findings in fibrostenosing Crohn's disease at CT and MR enterography El Sadaney, Ahmed O.; Baker, Mark E.; Ream, Justin; Bruining, David H.; Rieder, Florian; Hamza, Lena; Barlett, David J.; Fidler, Jeff L.; Denson, Lee A.; Dillman, Jonathan R.; Fletcher, Joel G. 分享 收藏
Missed strictures and penetrating complications on CT and MR enterography in Crohn's disease patients prior to anti-TNF therapy 在应用抗-TNF疗法之前，克罗恩病患者在CT和MR小肠造影中未发现严格的限制和穿透性并发症。 Hamza, Lena; El Sadaney, Ahmed O.; Baker, Mark E.; Ream, Justin; Bruining, David H.; Rieder, Florian; Fidler, Jeff L.; Denson, Lee A.; Dillman, Jonathan R.; Fletcher, Joel G. 分享 收藏
Islet Autoantibodies and Their Association With β-Cell Function and Diabetes Measures in Children With Acute Recurrent and Chronic Pancreatitis 胰岛自身抗体及其与急性复发性及慢性胰腺炎患儿β细胞功能与糖尿病指标的关系 Ginzburg, Gila; Hornung, Lindsey; Denson, Lee; Shah, Amy S.; Swauger, Sarah; Tatum, Jonathan; Tellez, Siobhan; Elder, Deborah; Bellin, Melena D.; Abu-El-Haija, Maisam 分享 收藏
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INTESTINAL E.COLI-PRODUCED YERSINIABACTIN INDUCES ZINC-DEPENDENT HIF-1A ACTIVATION TO PROMOTE PRO-FIBROTIC MACROPHAGES IN CROHN'S DISEASE 肠道大肠杆菌产生的耶尔辛菌素诱导锌依赖性HIF-1α活化，以促进克罗恩病中的促纤维化巨噬细胞。 Ahn, Ju-Hyun; Pedrosa, Marlus; Lopez, Lacey; Tibbs, Taylor; Jeyachandran, Joanna; Vignieri, Emily; Zamboni, William; Yu, Yen-Rei; Ellermann, Melissa; Denson, Lee; Arthur, Janelle 分享 收藏
AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN'S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS 使用多种内镜评分方法评估儿科克罗恩病内镜愈合情况，并识别血液和粪便生物标志物的相似性 Bartel, Courtney; Mizuno, Tomoyuki; Irie, Kei; Samuels, Abigail; Lynch, Kimberly; Jackson, Kimberly; Hyams, Jeffrey; Boyle, Brendan; Saeed, Shehzad; Kurowski, Jacob; Noe, Joshua; Chun, Kelly; Yang, Jane; Denson, Lee; Minar, Phillip 分享 收藏
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Fecal content from IBD patients causes more severe epithelial damage than fecal content from healthy donors, which can be moderated by supplementation of metabolites cocktail Abbas-Egbariya, H.; Elwahidi, L.; Braun, T.; Granot, M.; Krauthammer, A.; Loberman-Nachum, N.; Weiss, B.; Leichtmann-Bardoogo, Y.; Maoz, B.; Denson, L.; Gal-Mor, O.; Vandussen, K.; Amir, A.; Haberman Ziv, Y. 分享 收藏
Multi-omics analysis of Crohn's Disease trajectory from active to remission reveals that the altered ileal anti-bacterial epithelial signals and pathogenic microbial composition and metabolomics persist despite normalizing ileal immune signals during remission Haberman Ziv, Y.; Braun, T.; Levhar, N.; Efroni, G.; Hadar, R.; Jessula Levy, D.; Talan Asher, A.; Unger, B.; Picard, O.; Yablecovitch, D.; Kopylov, U.; Denson, L.; Eliakim, R.; Ben-Horin, S.; Amir, A. 分享 收藏
Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells 从多能干细胞中获得具有功能性组织驻留巨噬细胞的人类肠道类器官 Tominaga, Kentaro; Kechele, Daniel O.; Sanchez, J. Guillermo; Vales, Simon; Jurickova, Ingrid; Roman, Lizza; Asai, Akihiro; Enriquez, Jacob R.; Mccauley, Heather A.; Kishimoto, Keishi; Iwasawa, Kentaro; Singh, Akaljot; Horio, Yuko; Munera, Jorge O.; Takebe, Takanori; Zorn, Aaron M.; Helmrath, Michael A.; Denson, Lee A.; Wells, James M. 分享 收藏
Crohn's Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes 克罗恩病患者和健康婴儿对共生鞭毛蛋白肽表位具有免疫优势的b细胞反应 Zhao, Qing; Duck, Lennard Wayne; Killian Jr, John T.; Rosenberg, Alexander F.; Mannon, Peter J.; King, R. Glenn; Denson, Lee A.; Kugathasan, Subra; Janoff, Edward N.; Jenmalm, Maria C.; Elson, Charles O. 分享 收藏
The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children Abu-El-Haija, Maisam; Zhang, Wenying; Karns, Rebekah; Ginzburg, Gila; Vitale, David S.; Farrell, Peter; Nasr, Alexander; Ibrahim, Sherif; Bellin, Melena D.; Thompson, Tyler; Garlapally, Vineet; Woo, Jessica G.; Husain, Sohail Z.; Denson, Lee A. 分享 收藏
Duodenal transcriptomics demonstrates signatures of tissue inflammation and immune cell infiltration in children with environmental enteric dysfunction across global centers Marie, Chelsea; Das, Subhasish; Coomes, David; Ahmed, Tahmeed; Ali, S. Asad; Iqbal, Junaid; Kelly, Paul; Mahfuz, Mustafa; Moore, Sean R.; Petri, William A., Jr.; Tarr, Phillip I.; Denson, Lee A. 分享 收藏
Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project Xue, Mingyue; Leibovitzh, Haim; Shao, Jingcheng; Neustaeter, Anna; Dong, Mei; Xu, Wei; Espin-Garcia, Osvaldo; Griffiths, Anne M.; Steinhart, A. Hillary; Turner, Dan; Huynh, Hien Q.; Dieleman, Levinus A.; Panaccione, Remo; Aumais, Guy; Bressler, Brian; Bitton, Alain; Murthy, Sanjay; Marshall, John K.; Hyams, Jeffrey S.; Otley, Anthony; Bernstein, Charles N.; Moayyedi, Paul; El-Matary, Wael; Fich, Alexander; Denson, Lee A.; Ropeleski, Mark J.; Abreu, Maria T.; Deslandres, Colette; Cino, Maria; Avni-Biron, Irit; Lee, Sun-Ho; Turpin, Williams; Croitoru, Kenneth 分享 收藏
Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease Jurickova, Ingrid; Dreskin, Benjamin W.; Angerman, Elizabeth; Bonkowski, Erin; Nguyen, Jack; Villarreal, Richard; Tominaga, Kentaro; Iwasawa, Kentaro; Braun, Tzipi; Takebe, Takanori; Helmrath, Michael A.; Haberman, Yael; Wells, James M.; Denson, Lee A. 分享 收藏
Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway Ando, Tomoaki; Takazawa, Ikuo; Spencer, Zachary T.; Ito, Ryoji; Tomimori, Yoshiaki; Mikulski, Zbigniew; Matsumoto, Kenji; Ishitani, Tohru; Denson, Lee A.; Kawakami, Yu; Kawakami, Yuko; Kitaura, Jiro; Ahmed, Yashi; Kawakami, Toshiaki 分享 收藏
Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort Braun, Tzipi; Feng, Rui; Amir, Amnon; Levhar, Nina; Shacham, Hila; Mao, Ren; Hadar, Rotem; Toren, Itamar; Algavi, Yadid; Abu-Saad, Kathleen; Zhuo, Shuoyu; Efroni, Gilat; Malik, Alona; Picard, Orit; Yavzori, Miri; Agranovich, Bella; Liu, Ta-Chiang; Stappenbeck, Thaddeus S.; Denson, Lee; Kalter-Leibovici, Ofra; Gottlieb, Eyal; Borenstein, Elhanan; Elinav, Eran; Chen, Minhu; Ben-Horin, Shomron; Haberman, Yael 分享 收藏
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