未登录 Heart rate variability-based prediction of early cardiotoxicity in breast-cancer patients treated with anthracyclines and trastuzumab Espinola-Zavaleta, N.; Luna-Alcala, S.; Espejel-Guzman, A.; Lerma, C.; Leon, P.; Guerra, E. C.; Espinoza Fernandez, J. R.; Martinez-Dominguez, P.; Serrano-Roman, J.; Cabello-Ganem, A.; Aparicio-Ortiz, A. D.; Keirns, C.; Lerma, A.; Santa Ana-Bayona, M. J. 分享 收藏
The SOS1 Inhibitor MRTX0902 Blocks KRAS Activation and Demonstrates Antitumor Activity in Cancers Dependent on KRAS Nucleotide Loading SOS1抑制剂MRTX0902阻断KRAS激活并在依赖KRAS核苷酸负载的癌症中显示抗肿瘤活性 Sudhakar, Niranjan; Yan, Larry; Qiryaqos, Fadia; Engstrom, Lars D.; Laguer, Jade; Calinisan, Andrew; Hebbert, Allan; Waters, Laura; Moya, Krystal; Bowcut, Vickie; Vegar, Laura; Ketcham, John M.; Ivetac, Anthony; Smith, Christopher R.; Lawson, J. David; Rahbaek, Lisa; Clarine, Jeffrey; Nguyen, Natalie; Saechao, Barbara; Parker, Cody; Elliott, Adam J.; Vanderpool, Darin; He, Leo; Hover, Laura D.; Fernandez-Banet, Julio; Coma, Silvia; Pachter, Jonathan A.; Hallin, Jill; Marx, Matthew A.; Briere, David M.; Christensen, James G.; Olson, Peter; Haling, Jacob; Khare, Shilpi 分享 收藏
Discovery and characterization of potential drivers of resistance to the KRAS G12D inhibitor, MRTX1133, in cancer cell line models Helu, Xousaen M.; Griffiths, Ellie; Calinisan, Andrew; Hebbert, Allan; Yan, Larry; Hoffman, Natalie; Trinh, David; Hover, Laura; Fernandez-Banet, Julio; Briere, David M.; Lifset, Ella; Olson, Peter; Christensen, James G.; Hallin, Jill 分享 收藏
Identification of mechanism-based combination targets effective with the MTAcooperative PRMT5 inhibitor MRTX1719 for the treatment of MTAP deleted cancers Waters, Laura; Aranda, Ruth; Moya, Krystal; Bowcut, Victoria; Trinh, David; Hebbert, Allan; He, Leo; Hover, Laura D.; Fernandez-Banet, Julio; Hallin, Jill; Briere, David M.; Christensen, James G.; Olson, Peter A.; Engstrom, Lars D. 分享 收藏
Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor 一种有效的选择性非共价KRASG12D抑制剂的抗肿瘤功效 Hallin, Jill; Bowcut, Vickie; Calinisan, Andrew; Briere, David M.; Hargis, Lauren; Engstrom, Lars D.; Laguer, Jade; Medwid, James; Vanderpool, Darin; Lifset, Ella; Trinh, David; Hoffman, Natalie; Wang, Xiaolun; Lawson, J. David; Gunn, Robin J.; Smith, Christopher R.; Thomas, Nicole C.; Martinson, Matthew; Bergstrom, Alex; Sullivan, Francis; Bouhana, Karyn; Winski, Shannon; He, Leo; Fernandez-Banet, Julio; Pavlicek, Adam; Haling, Jacob R.; Rahbaek, Lisa; Marx, Matthew A.; Olson, Peter; Christensen, James G. 分享 收藏
The KRASG12C Inhibitor MRTX849 Reconditions the Tumor Immune Microenvironment and Sensitizes Tumors to Checkpoint Inhibitor Therapy Briere, David M.; Li, Shuai; Calinisan, Andrew; Sudhakar, Niranjan; Aranda, Ruth; Hargis, Lauren; Peng, David H.; Deng, Jiehui; Engstrom, Lars D.; Hallin, Jill; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Wong, Kwok-Kin; Christensen, James G.; Olson, Peter 分享 收藏
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The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients KRASG12C抑制剂MRTX849为小鼠模型和患者中KRAS突变癌症的治疗易感性提供了见解 Hallin, Jill; Engstrom, Lars D.; Hargis, Lauren; Calinisan, Andrew; Aranda, Ruth; Briere, David M.; Sudhakar, Niranjan; Bowcut, Vickie; Baer, Brian R.; Ballard, Joshua A.; Burkard, Michael R.; Fell, Jay B.; Fischer, John P.; Vigers, Guy P.; Xue, Yaohua; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Velastagui, Karen; Chao, Richard C.; Barton, Jeremy; Pierobon, Mariaelena; Baldelli, Elisa; Patricoin, Emanuel F., III; Cassidy, Douglas P.; Marx, Matthew A.; Rybkin, Igor I.; Johnson, Melissa L.; Ou, Sai-Hong Ignatius; Lito, Piro; Papadopoulos, Kyriakos P.; Janne, Pasi A.; Olson, Peter; Christensen, James G. 分享 收藏
The KRASG12C inhibitor MRTX849 reconditions the tumor immune microenvironment and leads to durable complete responses in combination with anti-PD-1 therapy in a syngeneic mouse model Briere, David M.; Calinisan, Andrew; Aranda, Ruth; Sudhakar, Niranjan; Hargis, Lauren; Gatto, Sole; Fernandez-Banet, Julio; Pavlicek, Adam; Engstrom, Lars D.; Hallin, Jill; Christensen, James G.; Olson, Peter 分享 收藏
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Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures Kan, Zhengyan; Ding, Ying; Kim, Jinho; Jung, Hae Hyun; Chung, Woosung; Lal, Samir; Cho, Soonweng; Fernandez-Banet, Julio; Lee, Se Kyung; Kim, Seok Won; Lee, Jeong Eon; Choi, Yoon-La; Deng, Shibing; Kim, Ji-Yeon; Ahn, Jin Seok; Sha, Ying; Mu, Xinmeng Jasmine; Nam, Jae-Yong; Im, Young-Hyuck; Lee, Soohyeon; Park, Woong-Yang; Nam, Seok Jin; Park, Yeon Hee 分享 收藏
Comparative analyses of multi-omics profiles reveal distinctive molecular signatures of young Asian breast cancers Park, Yeon Hee; Ding, Ying; Lee, Soo-Hyeon; Jung, Hae Hyun; Chung, Woosung; Cho, Soonweng; Kim, Jin-Ho; Deng, Shibing; Choi, Yoon-la; Fernandez, Julio; Lee, Se Kyung; Kim, Seok Won; Lee, Jeong Eon; Kim, Ji-Yeon; Ahn, Jin Seok; Im, Young-Hyuck; Nam, Seok Jin; Park, Woong-Yang; Kan, Zhengyan 分享 收藏
Multi-omics and immuno-oncology profiling reveal distinct molecular signatures of young Asian breast cancers Kan, Z.; Ding, Y.; Cho, S.; Lee, S-H; Powell, E.; Jung, H. H.; Chung, W.; Deng, S.; Choi, Y-IL; Kim, J.; Park, W-Y; Vizcarra, P.; Fernandez-Banet, J.; Nichols, T.; Ram, S.; Lee, S. K.; Kim, S. W.; Lee, J. E.; Ching, K. A.; Kim, J-Y; Ahn, J. S.; Im, Y-H; Nam, S. J.; Park, Y. H. 分享 收藏
The Ensembl gene annotation system Aken, Bronwen L.; Ayling, Sarah; Barrell, Daniel; Clarke, Laura; Curwen, Valery; Fairley, Susan; Banet, Julio Fernandez; Billis, Konstantinos; Giron, Carlos Garcia; Hourlier, Thibaut; Howe, Kevin; Kahari, Andreas; Kokocinski, Felix; Martin, Fergal J.; Murphy, Daniel N.; Nag, Rishi; Ruffier, Magali; Schuster, Michael; Tang, Y. Amy; Vogel, Jan-Hinnerk; White, Simon; Zadissa, Amonida; Flicek, Paul; Searle, Stephen M. J. 分享 收藏
Molecular profiling of patient-derived xenograft models across cancers Kan, Zhengyan; Rosfjord, Edward; Hardwick, James; Ding, Ying; Zheng, Xianxian; Fernandez, Julio; Shi, Stephanie; Ozeck, Mark; Wang, Hui; Troche, Gabriel; Upeslacis, Eric; Jackson-Fisher, Amy; Ching, Keith; Deng, Shibing; Tao, Xie; Chionis, John; Lira, Maruja; Li, Xiaorong; Tsaparikos, Konstantinos; Lappin, Patrick; Vizcarra, Pamela; Shields, David; Lucas, Judy; Rejto, Paul 分享 收藏
OASIS: A centralized portal for cancer omics data analysis Fernandez-Banet, Julio; Esposito, Anthony; Coffin, Scott; Schefzick, Sabine; Ding, Ying; Ching, Keith; Horvath, Istvan; Roberts, Peter; Rejto, Paul; Kan, Zhengyan 分享 收藏
The BioMart community portal: an innovative alternative to large, centralized data repositories Smedley, Damian; Haider, Syed; Durinck, Steffen; Pandini, Luca; Provero, Paolo; Allen, James; Arnaiz, Olivier; Awedh, Mohammad Hamza; Baldock, Richard; Barbiera, Giulia; Bardou, Philippe; Beck, Tim; Blake, Andrew; Bonierbale, Merideth; Brookes, Anthony J.; Bucci, Gabriele; Buetti, Iwan; Burge, Sarah; Cabau, Cedric; Carlson, Joseph W.; Chelala, Claude; Chrysostomou, Charalambos; Cittaro, Davide; Collin, Olivier; Cordova, Raul; Cutts, Rosalind J.; Dassi, Erik; Di Genova, Alex; Djari, Anis; Esposito, Anthony; Estrella, Heather; Eyras, Eduardo; Fernandez-Banet, Julio; Forbes, Simon; Free, Robert C.; Fujisawa, Takatomo; Gadaleta, Emanuela; Garcia-Manteiga, Jose M.; Goodstein, David; Gray, Kristian; Guerra-Assuncao, JoseE Afonso; Haggarty, Bernard; Han, Dong-Jin; Han, Byung Woo; Harris, Todd; Harshbarger, Jayson; Hastings, Robert K.; Hayes, Richard D.; Hoede, Claire; Hu, Shen; Hu, Zhi-Liang; Hutchins, Lucie; Kan, Zhengyan; Kawaji, Hideya; Keliet, Aminah; Kerhornou, Arnaud; Kim, Sunghoon; Kinsella, Rhoda; Klopp, Christophe; Kong, Lei; Lawson, Daniel; Lazarevic, Dejan; Lee, Ji-Hyun; Letellier, Thomas; Li, Chuan-Yun; Lio, Pietro; Liu, Chu-Jun; Luo, Jie; Maass, Alejandro; Mariette, Jerome; Maurel, Thomas; Merella, Stefania; Mohamed, Azza Mostafa; Moreews, Francois; Nabihoudine, Ibounyamine; Ndegwa, Nelson; Noirot, Celine; Perez-Llamas, Cristian; Primig, Michael; Quattrone, Alessandro; Quesneville, Hadi; Rambaldi, Davide; Reecy, James; Riba, Michela; Rosanoff, Steven; Saddiq, Amna Ali; Salas, Elisa; Sallou, Olivier; Shepherd, Rebecca; Simon, Reinhard; Sperling, Linda; Spooner, William; Staines, Daniel M.; Steinbach, Delphine; Stone, Kevin; Stupka, Elia; Teague, Jon W.; Ullah, Abu Z. Dayem; Wang, Jun; Ware, Doreen; Wong-Erasmus, Marie; Youens-Clark, Ken; Zadissa, Amonida; Zhang, Shi-Jian; Kasprzyk, Arek 分享 收藏
Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing Xie, Tao; Cho, Yong Beom; Wang, Kai; Huang, Donghui; Hong, Hye Kyung; Choi, Yoon-La; Ko, Young Hyeh; Nam, Do-Hyun; Jin, Juyoun; Yang, Heekyoung; Fernandez, Julio; Deng, Shibing; Rejto, Paul A.; Lee, Woo Yong; Mao, Mao 分享 收藏
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer Wang, Kai; Yuen, Siu Tsan; Xu, Jiangchun; Lee, Siu Po; Yan, Helen H. N.; Shi, Stephanie T.; Siu, Hoi Cheong; Deng, Shibing; Chu, Kent Man; Law, Simon; Chan, Kok Hoe; Chan, Annie S. Y.; Tsui, Wai Yin; Ho, Siu Lun; Chan, Anthony K. W.; Man, Jonathan L. K.; Foglizzo, Valentina; Ng, Man Kin; Chan, April S.; Ching, Yick Pang; Cheng, Grace H. W.; Xie, Tao; Fernandez, Julio; Li, Vivian S. W.; Clevers, Hans; Rejto, Paul A.; Mao, Mao; Leung, Suet Yi 分享 收藏
Decoding complex patterns of genomic rearrangement in hepatocellular carcinoma Fernandez-Banet, Julio; Lee, Nikki P.; Chan, Kin Tak; Gao, Huan; Liu, Xiao; Sung, Wing-Kin; Tan, Winnie; Fan, Sheung Tat; Poon, Ronnie T.; Li, Shiyong; Ching, Keith; Rejto, Paul A.; Mao, Mao; Kan, Zhengyan 分享 收藏
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