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收藏Targeting envelope lipids with 2,6-di-O-methyl-3-acetyl-β-cyclodextrin impairs infectivity of SARS-CoV-2 and Japanese encephalitis virusKusakari, D.; Kishimoto, N.; Oshiro, K.; Udeda, Y.; Takamune, N.; Motoyama, K.; Misumi, S. 使用2,6-二-O-甲基-3-乙酰基-β-环糊精靶向包膜脂质会损害SARS-CoV-2和日本脑炎病毒的感染性。J. Virol. 2025, 99, e01357-25. [Google Scholar] [CrossRef] [PubMed]
Kusakari, Daichi; Kishimoto, Naoki; Oshiro, Kazuyuki; Udeda, Yui; Takamune, Nobutoki; Motoyama, Keiichi; Misumi, Shogo 分享 收藏 An orally available P1′-5-fluorinated Mpro inhibitor blocks SARS-CoV-2 replication without booster and exhibits high genetic barrierHigashi-Kuwata, Nobuyo; Bulut, Haydar; Hayashi, Hironori; Tsuji, Kohei; Ogata-Aoki, Hiromi; Kiso, Maki; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Shimizu, Yukiko; Das, Debananda; Saruwatari, Junji; Hasegawa, Kazuya; Murayama, Kazutaka; Sukenaga, Yoshikazu; Takamatsu, Yuki; Yoshimura, Kazuhisa; Aoki, Manabu; Furusawa, Yuri; Okamura, Tadashi; Yamayoshi, Seiya; Kawaoka, Yoshihiro; Misumi, Shogo; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 Structural and virologic mechanism of the emergence of resistance to M pro inhibitors in SARS-CoV-2Hattori, Shin-ichiro; Bulut, Haydar; Hayashi, Hironori; Kishimoto, Naoki; Takamune, Nobutoki; Hasegawa, Kazuya; Furusawa, Yuri; Yamayoshi, Seiya; Murayama, Kazutaka; Tamamura, Hirokazu; Li, Mi; Wlodawer, Alexander; Kawaoka, Yoshihiro; Misumi, Shogo; Mitsuya, Hiroaki 分享 收藏 分享 收藏 GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variantsAoki, Manabu; Aoki-Ogata, Hiromi; Bulut, Haydar; Hayashi, Hironori; Takamune, Nobutoki; Kishimoto, Naoki; Tanaka, Hiroki; Higashi-Kuwata, Nobuyo; Hattori, Shin-ichiro; Das, Debananda; Rao, Kalapala Venkateswara; Iwama, Kazuya; Davis, David A.; Hasegawa, Kazuya; Murayama, Kazutaka; Yarchoan, Robert; Ghosh, Arun K.; Pau, Alice K.; Machida, Shinichi; Misumi, Shogo; Mitsuya, Hiroaki 分享 收藏 Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2Higashi-Kuwata, Nobuyo; Tsuji, Kohei; Hayashi, Hironori; Bulut, Haydar; Kiso, Maki; Imai, Masaki; Ogata-Aoki, Hiromi; Ishii, Takahiro; Kobayakawa, Takuya; Nakano, Kenta; Takamune, Nobutoki; Kishimoto, Naoki; Hattori, Shin-ichiro; Das, Debananda; Uemura, Yukari; Shimizu, Yosuke; Aoki, Manabu; Hasegawa, Kazuya; Suzuki, Satoshi; Nishiyama, Akie; Saruwatari, Junji; Shimizu, Yukiko; Sukenaga, Yoshikazu; Takamatsu, Yuki; Tsuchiya, Kiyoto; Maeda, Kenji; Yoshimura, Kazuhisa; Iida, Shun; Ozono, Seiya; Suzuki, Tadaki; Okamura, Tadashi; Misumi, Shogo; Kawaoka, Yoshihiro; Tamamura, Hirokazu; Mitsuya, Hiroaki 分享 收藏 分享 收藏 Identification of a novel long-acting 4′-modified nucleoside reverse transcriptase inhibitor against HBVHigashi-Kuwata, Nobuyo; Hayashi, Sanae; Kumamoto, Hiroki; Ogata-Aoki, Hiromi; Das, Debananda; Venzon, David; Hattori, Shin-ichiro; Bulut, Haydar; Hashimoto, Mai; Otagiri, Masaki; Takamune, Nobutoki; Kishimoto, Naoki; Davis, David A.; Misumi, Shogo; Kakuni, Masakazu; Tanaka, Yasuhito; Mitsuya, Hiroaki 分享 收藏 A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replicationHattori, Shin-ichiro; Higashi-Kuwata, Nobuyo; Hayashi, Hironori; Allu, Srinivasa Rao; Raghavaiah, Jakka; Bulut, Haydar; Das, Debananda; Anson, Brandon J.; Lendy, Emma K.; Takamatsu, Yuki; Takamune, Nobutoki; Kishimoto, Naoki; Murayama, Kazutaka; Hasegawa, Kazuya; Li, Mi; Davis, David A.; Kodama, Eiichi N.; Yarchoan, Robert; Wlodawer, Alexander; Misumi, Shogo; Mesecar, Andrew D.; Ghosh, Arun K.; Mitsuya, Hiroaki 分享 收藏 GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 InfectionGRL-0920，一种吲哚氯吡啶基酯，完全阻断SARS-CoV-2感染Hattori, Shin-ichiro; Higshi-Kuwata, Nobuyo; Raghavaiah, Jakka; Das, Debananda; Bulut, Haydar; Davis, David A.; Takamatsu, Yuki; Matsuda, Kouki; Takamune, Nobutoki; Kishimoto, Naoki; Okamura, Tadashi; Misumi, Shogo; Yarchoan, Robert; Maeda, Kenji; Ghosh, Arun K.; Mitsuya, Hiroaki 分享 收藏 A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potencyAoki, Manabu; Hayashi, Hironori; Rao, Kalapala Venkateswara; Das, Debananda; Higashi-Kuwata, Nobuyo; Bulut, Haydar; Aoki-Ogata, Hiromi; Takamatsu, Yuki; Yedidi, Ravikiran S.; Davis, David A.; Hattori, Shin-ichiro; Nishida, Noriko; Hasegawa, Kazuya; Takamune, Nobutoki; Nyalapatla, Prasanth R.; Osswald, Heather L.; Jono, Hirofumi; Saito, Hideyuki; Yarchoan, Robert; Misumi, Shogo; Ghosh, Arun K.; Mitsuya, Hiroaki 分享 收藏 分享 收藏 Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavirHayashi, Hironori; Takamune, Nobutoki; Nirasawa, Takashi; Aoki, Manabu; Morishita, Yoshihiko; Das, Debananda; Koh, Yasuhiro; Ghosh, Arun K.; Misumi, Shogo; Mitsuya, Hiroaki 分享 收藏 分享 收藏 Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young ChildrenSturdevant, Christa Buckheit; Dow, Anna; Jabara, Cassandra B.; Joseph, Sarah B.; Schnell, Gretja; Takamune, Nobutoki; Mallewa, Macpherson; Heyderman, Robert S.; Van Rie, Annelies; Swanstrom, Ronald 分享 收藏 分享 收藏 Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugateOhtsuka, Keiichi; Sato, Shinobu; Sato, Yusuke; Sota, Kojiro; Ohzawa, Shinsuke; Matsuda, Tomoki; Takemoto, Kiwamu; Takamune, Nobutoki; Juskowiak, Bernard; Nagai, Takeharu; Takenaka, Shigeori 分享 收藏 分享 收藏 Targeted Delivery of Immunogen to Primate M Cells with Tetragalloyl Lysine DendrimerMisumi, Shogo; Masuyama, Mitsuaki; Takamune, Nobutoki; Nakayama, Daisuke; Mitsumata, Ryotarou; Matsumoto, Hirokazu; Urata, Norimitsu; Takahashi, Yoshihiro; Muneoka, Atsunobu; Sukamoto, Takayuki; Fukuzaki, Koichiro; Shoji, Shozo 分享 收藏 
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