arrow
返回
D

David Segal

walter & eliza hall institute

27H指数
63论文数
4.0K被引数
收录论文 25
发表时间
New experimental methodology to evaluate lubrication properties of synovial fluid containing worn tissue particles in osteoarthritis patients
err2023-05-11
err2
errOAAI
errDvir, Israel; Abd-Rbo, Kareem; Segal, David; Kandel, Leonid (Arieh); Kasem, Haytam
err分享
err收藏
PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period
err2023-05-01
err14
errOAAI
errPhilpott, Jonathan M.; Freeberg, Alfred M.; Park, Jiyoung; Lee, Kwangjun; Ricci, Clarisse G.; Hunt, Sabrina R.; Narasimamurthy, Rajesh; Segal, David H.; Robles, Rafael; Cai, Yao; Tripathi, Sarvind; McCammon, J. Andrew; Virshup, David M.; Chiu, Joanna C.; Lee, Choogon; Partch, Carrie L.
err分享
err收藏
Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2
err2021-04-27
err8
PREAI
errRoy, Michael J.; Vom, Amelia; Okamoto, Toru; Smith, Brian J.; Birkinshaw, Richard W.; Yang, Hong; Abdo, Houda; White, Christine A.; Segal, David; Huang, David C. S.; Baell, Jonathan B.; Colman, Peter M.; Czabotar, Peter E.; Lessene, Guillaume
err分享
err收藏
Defining the susceptibility of colorectal cancers to BH3-mimetic compounds
err2020-09-10
err14
errOAAI
errLuo, Ming-Jie; Palmieri, Michelle; Riffkin, Chris D.; Sakthianandeswaren, Anuratha; Djajawi, Tirta Mario; Hirokawa, Yumiko; Shuttleworth, Victoria; Segal, David H.; White, Christine A.; Nhu, Duong; Lessene, Guillaume; Lee, Margaret; Gibbs, Peter; Huang, David C. S.; Sieber, Oliver M.; Gong, Jia-nan
err分享
err收藏
Loss of RIPK3 does not impact MYC-driven lymphomagenesis or chemotherapeutic drug-induced killing of malignant lymphoma cells
err2020-06-18
err8
errOAAI
errThijssen, Rachel; Alvarez-Diaz, Silvia; Grace, Clea; Gao, Ming-yuan; Segal, David H.; Xu, Zhen; Strasser, Andreas; Huang, David C. S.
err分享
err收藏
Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells
err2020-01-27
err27
errOAAI
errTeh, Charis E.; Gong, Jia-Nan; Segal, David; Tan, Tania; Vandenberg, Cassandra J.; Fedele, Pasquale L.; Low, Michael S. Y.; Grigoriadis, George; Harrison, Simon J.; Strasser, Andreas; Roberts, Andrew W.; Huang, David C. S.; Nolan, Garry P.; Gray, Daniel H. D.; Ko, Melissa E.
err分享
err收藏
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
err2019-10-07
err29
PREAI
errvan Delft, Mark F.; Chappaz, Stephane; Khakham, Yelena; Chinh T Bui; Debrincat, Marlyse A.; Lowes, Kym N.; Brouwer, Jason M.; Grohmann, Christoph; Sharp, Phillip P.; Dagley, Laura F.; Li, Lucy; McArthur, Kate; Luo, Meng-Xiao; Chin, Hui San; Fairlie, W. Douglas; Lee, Erinna F.; Segal, David; Duflocq, Stephane; Lessene, Romina; Bernard, Sabrina; Peilleron, Laure; Thao Nguyen; Miles, Caroline; Wan, Soo San; Lane, Rachael M.; Wardak, Ahmad; Lackovic, Kurt; Colman, Peter M.; Sandow, Jarrod J.; Webb, Andrew, I; Czabotar, Peter E.; Dewson, Grant; Watson, Keith G.; Huang, David C. S.; Lessene, Guillaume; Kile, Benjamin T.
err分享
err收藏
BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival
err2019-04-24
err157
errOAAI
errLee, Erinna F.; Harris, Tiffany J.; Tran, Sharon; Evangelista, Marco; Arulananda, Surein; John, Thomas; Ramnac, Celeste; Hobbs, Chloe; Zhu, Haoran; Gunasingh, Gency; Segal, David; Behren, Andreas; Cebon, Jonathan; Dobrovic, Alexander; Mariadason, John M.; Strasser, Andreas; Rohrbeck, Leona; Haass, Nikolas K.; Herold, Marco J.; Fairlie, W. Douglas
err分享
err收藏
Therapeutic Effects of a TANK-Binding Kinase 1 Inhibitor in Germinal Center-Driven Collagen-Induced Arthritis
err2018-11-26
err20
errOAAI
errLouis, Cynthia; Ngo, Devi; D'Silva, Damian B.; Hansen, Jacinta; Phillipson, Louisa; Jousset, Helene; Novello, Patrizia; Segal, David; Lawlor, Kate E.; Burns, Christopher J.; Wicks, Ian P.
err分享
err收藏
Combining BH3-mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia
errLEUKEMIA
IF13.4
err2018-09-10
err138
errOAAI
errMoujalled, Donia M.; Pomilio, Giovanna; Ghiurau, Corina; Ivey, Adam; Salmon, Jessica; Rijal, Sewa; Macraild, Sarah; Zhang, Lan; Teh, Tse-Chieh; Tiong, Ing-Soo; Lan, Ping; Chanrion, Maia; Claperon, Audrey; Rocchetti, Francesca; Zichi, Adrien; Kraus-Berthier, Laurence; Wang, Youzhen; Hamovic, Ensar; Morris, Erick; Colland, Frederic; Segal, David; Huang, David; Roberts, Andrew W.; Maragno, Ana Leticia; Lessene, Guillaume; Geneste, Olivier; Wei, Andrew H.
err分享
err收藏
Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors
err2017-12-01
err28
errOAAI
errSharp, Phillip P.; Garnier, Jean-Marc; Hatfaludi, Tamas; Xu, Zhen; Segal, David; Jarman, Kate E.; Jousset, Helene; Garnham, Alexandra; Feutrill, John T.; Cuzzupe, Anthony; Hall, Peter; Taylor, Scott; Walkley, Carl R.; Tyler, Dean; Dawson, Mark A.; Czabotar, Peter; Wilks, Andrew F.; Glaser, Stefan; Huang, David C. S.; Burns, Christopher J.
err分享
err收藏
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer
err2017-08-02
err165
PREAI
errMerino, Delphine; Whittle, James R.; Vaillant, Francois; Serrano, Antonin; Gong, Jia-Nan; Giner, Goknur; Maragno, Ana Leticia; Chanrion, Maia; Schneider, Emilie; Pal, Bhupinder; Li, Xiang; Dewson, Grant; Grasel, Julius; Liu, Kevin; Lalaoui, Najoua; Segal, David; Herold, Marco J.; Huang, David C. S.; Smyth, Gordon K.; Geneste, Olivier; Lessene, Guillaume; Visvader, Jane E.; Lindeman, Geoffrey J.
err分享
err收藏
Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1
errLEUKEMIA
IF13.4
err2017-07-28
err128
PREAI
errTeh, T-C; Nguyen, N-Y; Moujalled, D. M.; Segal, D.; Pomilio, G.; Rijal, S.; Jabbour, A.; Cummins, K.; Lackovic, K.; Blombery, P.; Thompson, E.; Ekert, P. G.; Lessene, G.; Glaser, S. P.; Huang, D. C. S.; Roberts, A. W.; Guthridge, M. A.; Wei, A. H.
err分享
err收藏
Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins
err2017-04-24
err11
errOAAI
errAntignani, A.; Segal, D.; Simon, N.; Kreitman, R. J.; Huang, D.; FitzGerald, D. J.
err分享
err收藏
DR5 and caspase-8 are dispensable in ER stress-induced apoptosis
err2017-04-14
err73
errOAAI
errGlab, Jason A.; Doerflinger, Marcel; Nedeva, Christina; Jose, Irvin; Mbogo, George W.; Paton, James C.; Paton, Adrienne W.; Kueh, Andrew J.; Herold, Marco J.; Huang, David C. S.; Segal, David; Brumatti, Gabriella; Puthalakath, Hamsa
err分享
err收藏
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
err2017-03-31
err113
errOAAI
errCarrington, Emma M.; Zhan, Yifan; Brady, Jamie L.; Zhang, Jian-Guo; Sutherland, Robyn M.; Anstee, Natasha S.; Schenk, Robyn L.; Vikstrom, Ingela B.; Delconte, Rebecca B.; Segal, David; Huntington, Nicholas D.; Bouillet, Philippe; Tarlinton, David M.; Huang, David C. S.; Strasser, Andreas; Cory, Suzanne; Herold, Marco J.; Lew, Andrew M.
err分享
err收藏
Combination of IAP antagonist and IFNγ activates novel caspase-10-and RIPK1-dependent cell death pathways
err2017-01-20
err43
errOAAI
errTanzer, Maria C.; Khan, Nufail; Rickard, James A.; Etemadi, Nima; Lalaoui, Najoua; Spall, Sukhdeep Kaur; Hildebrand, Joanne M.; Segal, David; Miasari, Maria; Chau, Diep; Wong, WendyWei-Lynn; McKinlay, Mark; Chunduru, Srinivas K.; Benetatos, Christopher A.; Condon, Stephen M.; Vince, James E.; Herold, Marco J.; Silke, John
err分享
err收藏
BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells
errLEUKEMIA
IF13.4
err2016-03-08
err30
PREAI
errXu, Z.; Sharp, P. P.; Yao, Y.; Segal, D.; Ang, C. H.; Khaw, S. L.; Aubrey, B. J.; Gong, J.; Kelly, G. L.; Herold, M. J.; Strasser, A.; Roberts, A. W.; Alexander, W. S.; Burns, C. J.; Huang, D. C. S.; Glaser, S. P.
err分享
err收藏
Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9
err2015-10-01
err37
PREAI
errPhillipson, Louisa J.; Segal, David H.; Nero, Tracy L.; Parker, Michael W.; Wan, Soo San; de Silva, Melanie; Guthridge, Mark A.; Wei, Andrew H.; Burns, Christopher J.
err分享
err收藏
Who's in the driver's seat? Identifying causative variants of colorectal cancer
err2015-08-01
err0
PREAI
errCoggins, Nicole; Carvajal-Carmona, Luis; Segal, David
err分享
err收藏