Jürgen Thomale - Publications, H-index & Citations

Jürgen Thomale

university hospital essen

32H指数

113论文数

3.9K被引数

收录论文 28

发表时间

Cell-cycle-specific lesion evolution rather than inhibition of double-strand-break repair underpins cisplatin radiosensitization 细胞周期特异性损伤演变而非双链断裂修复的抑制是顺铂放射增敏的基础

Molecular Oncology

IF4.5

2026-03-19

OAAI

Ye Qiu; Xixi Lin; Emil Mladenov; Veronika Mladenova; Jürgen Thomale; Ali Sak; Yao Wang; Yunxuan Deng; Eleni Gkika; Martin Stuschke; George Iliakis

Effects of hyperthermia on cisplatin tissue penetration and gene expression in peritoneal metastases: results from a randomized trial in ovarian cancer 热疗对腹膜转移的顺铂组织渗透和基因表达的影响: 卵巢癌随机试验的结果

BRITISH JOURNAL OF SURGERY

IF8.7

2024-04-24

PREAI

Demuytere, Jesse; Carlier, Charlotte; Van Helden, Tom; Belza, Joke; Vanhaecke, Frank; Xie, Feifan; Vermeulen, An; Weerts, Joseph; Thomale, Jurgen; Denys, Hannelore; Tummers, Philippe; Van Kerschaver, Olivier; Willaert, Wouter; Cosyns, Sarah; Merseburger, Peter; Claeys, Arne; van den Eynden, Jimmy; Ceelen, Wim

Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells

MOLECULAR ONCOLOGY

IF4.5

2020-03-10

OAAI

Melnikova, Margarita; Wauer, Ulrike Sophie; Mendus, Diana; Hilger, Ralf Axel; Oliver, Trudy G.; Mercer, Kim; Gohlke, Bjoern Oliver; Erdmann, Kati; Niederacher, Dieter; Neubauer, Hans; Buderath, Paul; Wimberger, Pauline; Kuhlmann, Jan Dominik; Thomale, Juergen

Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities

SCIENTIFIC REPORTS

IF3.9

2019-02-04

OAAI

Riaz, Muhammad Assad; Sak, Ali; Erol, Yasin Bahadir; Groneberg, Michael; Thomale, Jurgen; Stuschke, Martin

Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair

ONCOGENE

IF7.3

2019-01-16

OAAI

Seoane, Marcos; Buhs, Sophia; Iglesias, Pablo; Strauss, Julia; Puller, Ann-Christin; Mueller, Juergen; Gerull, Helwe; Feldhaus, Susanne; Alawi, Malik; Brandner, Johanna M.; Eggert, Dennis; Du, Jinyan; Thomale, Juergen; Wild, Peter J.; Zimmermann, Martin; Sternsdorf, Thomas; Schumacher, Udo; Nollau, Peter; Fisher, David E.; Horstmann, Martin A.

Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2017-09-01

PREAI

Sanchez-Gonzalez, Penelope D.; Lopez-Hernandez, Francisco J.; Duenas, Montserrat; Prieto, Marta; Sanchez-Lopez, Elsa; Thomale, Juergen; Ruiz-Ortega, Marta; Lopez-Novoa, Jose M.; Morales, Ana I.

Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2017-07-12

OAAI

Kritsch, Daniel; Hoffmann, Franziska; Steinbach, Daniel; Jansen, Lars; Photini, Stella Mary; Gajda, Mieczyslaw; Mosig, Alexander S.; Sonnemann, Juergen; Peters, Sven; Melnikova, Margarita; Thomale, Juergen; Duerst, Matthias; Runnebaum, Ingo B.; Haefner, Norman

Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner

MOLECULAR CANCER RESEARCH

IF4.7

2016-11-10

OAAI

Jokic, Mladen; Vlasic, Ignacija; Rinneburger, Miriam; Kluemper, Niklas; Spiro, Judith; Vogel, Wenzel; Offermann, Anne; Kuempers, Christiane; Fritz, Christian; Schmitt, Anna; Riabinska, Arina; Wittersheim, Maike; Michels, Sebastian; Ozretic, Luka; Florin, Alexandra; Welcker, Daniela; Akyuz, Mehmet Deniz; Nowak, Michael; Erkel, Martin; Wolf, Juergen; Buettner, Reinhard; Schumacher, Bjoern; Thomale, Juergen; Persigehl, Thorsten; Maintz, David; Perner, Sven; Reinhardt, Hans Christian

DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression 涉及DNA聚合酶 ι 和肿瘤抑制因子p53的DNA损伤耐受途径调节DNA复制叉进展

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-07-12

OAAI

Hamppa, Stephanie; Kiesslinga, Tina; Buechlea, Kerstin; Mansilla, Sabrina F.; Thomalec, Juergen; Rall, Melanie; Ahn, Jinwoo; Pospiech, Helmut; Gottifredi, Vanesa; Wiesmueller, Lisa

Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2016-02-01

PREAI

Krueger, Katharina; Ziegler, Verena; Hartmann, Christina; Henninger, Christian; Thomale, Juergen; Schupp, Nicole; Fritz, Gerhard

ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma

NUCLEIC ACIDS RESEARCH

IF13.1

2016-01-26

OAAI

Bretz, Anne Catherine; Gittler, Miriam P.; Charles, Joel P.; Gremke, Niklas; Eckhardt, Ines; Mernberger, Marco; Mandic, Robert; Thomale, Juergen; Nist, Andrea; Wanzel, Michael; Stiewe, Thorsten

Formation and repair kinetics of Pt-(GpG) DNA adducts in extracted circulating tumour cells and response to platinum treatment

BRITISH JOURNAL OF CANCER

IF6.8

2013-08-13

OAAI

Nel, I.; Gauler, T. C.; Eberhardt, W. E.; Nickel, A-C; Schuler, M.; Thomale, J.; Hoffmann, A-C

ERCC1 Isoform Expression and DNA Repair in Non-Small-Cell Lung Cancer

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2013-03-21

324

OAAI

Friboulet, Luc; Olaussen, Ken Andre; Pignon, Jean-Pierre; Shepherd, Frances A.; Tsao, Ming-Sound; Graziano, Stephen; Kratzke, Robert; Douillard, Jean-Yves; Seymour, Lesley; Pirker, Robert; Filipits, Martin; Andre, Fabrice; Solary, Eric; Ponsonnailles, Florence; Robin, Angelique; Stoclin, Annabelle; Dorvault, Nicolas; Commo, Frederic; Adam, Julien; Vanhecke, Elsa; Saulnier, Patrick; Thomale, Juergen; Le Chevalier, Thierry; Dunant, Ariane; Rousseau, Vanessa; Le Teuff, Gwenael; Brambilla, Elisabeth; Soria, Jean-Charles

FTO levels affect RNA modification and the transcriptome FTO水平影响RNA修饰和转录组

EUROPEAN JOURNAL OF HUMAN GENETICS

IF4.6

2012-08-08

OAAI

Berulava, Tea; Ziehe, Matthias; Klein-Hitpass, Ludger; Mladenov, Emil; Thomale, Juergen; Ruether, Ulrich; Horsthemke, Bernhard

Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells

MOLECULAR CANCER

IF33.9

2011-01-01

OAAI

Wang, Qi-En; Milum, Keisha; Han, Chunhua; Huang, Yi-Wen; Wani, Gulzar; Thomale, Juergen; Wani, Altaf A.

Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression

MOLECULAR CANCER

IF33.9

2010-09-16

155

OAAI

Usanova, Svetlana; Piee-Staffa, Andrea; Sied, Ulrike; Thomale, Juergen; Schneider, Astrid; Kaina, Bernd; Koeberle, Beate

Chlorambucil-Adducts in DNA Analyzed at the Oligonucleotide Level Using HPLC-ESI MS

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2009-07-22

PREAI

Mohamed, Dalia; Mowaka, Shereen; Thomale, Juergen; Linscheid, Michael W.

Reciprocal relationship between O6-methylguanine-DNA methyltransferase P140K expression level and chemoprotection of hematopoletic stem cells

CANCER RESEARCH

IF16.6

2008-08-01

OAAI

Milsom, Michael D.; Jerabek-Willemsen, Moran; Harris, Chad E.; Schambach, Axel; Broun, Emily; Bailey, Jeff; Jansen, Michael; Schleimer, David; Nattamai, Kalpana; Wilhelm, Jamie; Watson, Amanda; Geiger, Hartmut; Margison, Geoffrey P.; Moritz, Thomas; Baum, Christopher; Thomale, Juergen; Williams, David A.

Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device 使用叶酸作为归巢装置的靶向单壁碳纳米管介导的Pt(IV) 前药递送

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2008-07-29

671

OAAI

Dhar, Shanta; Liu, Zhuang; Thomale, Juergen; Dai, Hongjie; Lippard, Stephen J.

O6-methylguanine-DNA-methyltransferase (MGMT) gene therapy targeting haematopoietic stem cells:: Studies addressing safety issues

DNA REPAIR

IF2.7

2007-08-01

PREAI

Sorg, Ursula R.; Kleff, Veronika; Fanaei, Sepideh; Schumann, Alexandra; Moellmann, Michael; Opalka, Bertram; Thomale, Juergen; Moritz, Thomas

研究方向