未登录 Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 IRAK4抑制剂BAY1834845 (Zabedosertib) 和BAY1830839的发现 Bothe, Ulrich; Guenther, Judith; Nubbemeyer, Reinhard; Siebeneicher, Holger; Ring, Sven; Boemer, Ulf; Peters, Michaele; Rausch, Alexandra; Denner, Karsten; Himmel, Herbert; Sutter, Andreas; Terebesi, Ildiko; Lange, Martin; Wengner, Antje M.; Guimond, Nicolas; Thaler, Tobias; Platzek, Johannes; Eberspaecher, Uwe; Schaefer, Martina; Steuber, Holger; Zollner, Thomas M.; Steinmeyer, Andreas; Schmidt, Nicole 分享 收藏
Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist Mesch, Stefanie; Walter, Daryl; Laux-Biehlmann, Alexis; Basting, Daniel; Flanagan, Stuart; Ondozabal, Hideki Miyatake; Baeurle, Stefan; Pearson, Christopher; Jenkins, James; Elves, Philip; Hess, Stephen; Coelho, Anne-Marie; Rotgeri, Andrea; Bothe, Ulrich; Nawaz, Schanila; Zollner, Thomas M.; Steinmeyer, Andreas 分享 收藏
Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women Panknin, Olaf; Wagenfeld, Andrea; Bone, Wilhelm; Bender, Eckhard; Nowak-Reppel, Katrin; Fernandez-Montalvan, Amaury E.; Nubbemeyer, Reinhard; Baeurle, Stefan; Ring, Sven; Schmees, Norbert; Prien, Olaf; Schaefer, Martina; Friedrich, Christian; Zollner, Thomas M.; Steinmeyer, Andreas; Mueller, Thomas; Langer, Gernot 分享 收藏
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions (vol 10, 1495, 2020) Thezenas, Marie-Laetitia; De Leo, Bianca; Laux-Biehlmann, Alexis; Bafligil, Cemsel; Elger, Bernd; Tapmeier, Thomas; Morten, Karl; Rahmioglu, Nilufer; Dakin, Stephanie G.; Charles, Philip; Martinez, Fernando E. Strada; Steers, Graham; Fischer, Oliver M.; Mueller, Joerg; Hess-Stumpp, Holger; Steinmeyer, Andreas; Manek, Sanjiv; Zondervan, Krina T.; Kennedy, Stephen; Becker, Christian M.; Shang, Catherine; Zollner, Thomas M.; Kessler, Benedikt M.; Oppermann, Udo 分享 收藏
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions Thezenas, Marie-Laetitia; De Leo, Bianca; Laux-Biehlmann, Alexis; Bafligil, Cemsel; Elger, Bernd; Tapmeier, Thomas; Morten, Karl; Rahmioglu, Nilufer; Dakin, Stephanie G.; Charles, Philip; Martinez, Fernando Estrada; Steers, Graham; Fischer, Oliver M.; Mueller, Joerg; Hess-Stumpp, Holger; Steinmeyer, Andreas; Manek, Sanjiv; Zondervan, Krina T.; Kennedy, Stephen; Becker, Christian M.; Shang, Catherine; Zollner, Thomas M.; Kessler, Benedikt M.; Oppermann, Udo 分享 收藏
Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile Werner, Stefan; Mesch, Stefanie; Hillig, Roman C.; ter Laak, Antonius; Klint, Julie; Neagoe, Ioana; Laux-Biehlmann, Alexis; Dahlloef, Henrik; Braeuer, Nico; Puetter, Vera; Nubbemeyer, Reinhard; Schulz, Simone; Bairlein, Michaela; Zollner, Thomas M.; Steinmeyer, Andreas 分享 收藏
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Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis Baeurle, Stefan; Nagel, Jens; Peters, Olaf; Braeuer, Nico; ter Laak, Antonius; Preusse, Cornelia; Rottmann, Antje; Heldmann, Dieter; Bothe, Ulrich; Blume, Thorsten; Zorn, Ludwig; Walter, Daryl; Zollner, Thomas M.; Steinmeyer, Andreas; Langer, Gernot 分享 收藏
Preclinical evaluation of a novel interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in combination with PI3K inhibitor copanlisib or BTK inhibitors in ABC-DLBCL Lange, Martin; Wengner, Antje Margret; Bothe, Ulrich; Boemer, Ulf; Nubbemeyer, Reinhard; Siebeneicher, Holger; Steuber, Holger; Guenther, Judith; Potze, Lisette; Schmidt, Nicole; Politz, Oliver; Doecke, Wolf-Dietrich; Lagkadinou, Eleni; Zollner, Thomas M.; von Nussbaum, Franz; Mumberg, Dominik; Steinmeyer, Andreas; Brands, Michael; Ziegelbauer, Karl 分享 收藏
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Vitamin D Is Required for IFN-γ-Mediated Antimicrobial Activity of Human Macrophages Fabri, Mario; Stenger, Steffen; Shin, Dong-Min; Yuk, Jae-Min; Liu, Philip T.; Realegeno, Susan; Lee, Hye-Mi; Krutzik, Stephan R.; Schenk, Mirjam; Sieling, Peter A.; Teles, Rosane; Montoya, Dennis; Iyer, Shankar S.; Bruns, Heiko; Lewinsohn, David M.; Hollis, Bruce W.; Hewison, Martin; Adams, John S.; Steinmeyer, Andreas; Zuegel, Ulrich; Cheng, Genhong; Jo, Eun-Kyeong; Bloom, Barry R.; Modlin, Robert L. 分享 收藏
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1,25-Dihydroxyvitamin D3 Is an Autonomous Regulator of the Transcriptional Changes Leading to a Tolerogenic Dendritic Cell Phenotype Szeles, Lajos; Keresztes, Gabor; Toeroecsik, Daniel; Balajthy, Zoltan; Krenacs, Laszlo; Poliska, Szilard; Steinmeyer, Andreas; Zuegel, Ulrich; Pruenster, Monika; Rot, Antal; Nagy, Laszlo 分享 收藏
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