John J. Mekalanos - Publications, H-index & Citations

John J. Mekalanos

harvard medical school

126H指数

379论文数

5.5W被引数

收录论文 111

发表时间

Pandemic Vibrio cholerae and the Environmental Reservoir Hypothesis—Outstanding Questions Central to Global Cholera Control 霍乱弧菌大流行与环境储存库假说——全球霍乱控制中的核心问题

Environmental Microbiology

IF4

2026-04-30

OAAI

Azfar D. Hossain; William P. Robins; John J. Mekalanos; Louise C. Ivers

Natural directed evolution in gut microbiota 肠道微生物组的自然定向进化

Science

IF45.8

2025-10-09

PREAI

Blair G. Paul; John J. Mekalanos

A coordinated attack by a bacterial secretion system and a small molecule drives prey specificity

COMMUNICATIONS BIOLOGY

IF5.1

2024-08-08

OAAI

Bier, S. B.; Toska, J.; Zhao, W.; Suthianthong, P.; Proespraiwong, P.; Robins, W. P.; Mekalanos, J.

DdmABC-dependent death triggered by viral palindromic DNA sequences 病毒回文DNA序列引发的DdmABC依赖性死亡

CELL REPORTS

IF6.9

2024-07-01

OAAI

Robins, William P.; Meader, Bradley T.; Toska, Jonida; Mekalanos, John J.

Culture of attenuated Salmonella Typhimurium VNP20009 in animal-product-free media does not alter schwannoma growth control

HUMAN VACCINES & IMMUNOTHERAPEUTICS

IF3.5

2023-10-03

OAAI

Ahmed, Sherif G.; Oliva, Giulia; Shao, Manlin; Mekalanos, John J.; Brenner, Gary J.

A high-throughput sequencing approach identifies immunotherapeutic targets for bacterial meningitis in neonates

EBIOMEDICINE

IF10.8

2023-02-01

OAAI

Pons, Stephanie; Frapy, Eric; Sereme, Youssouf; Gaultier, Charlotte; Lebreton, Francois; Kropec, Andrea; Danilchanka, Olga; Schlemmer, Laura; Schrimpf, Cecile; Allain, Margaux; Angoulvant, Francois; Lecuyer, Herve; Bonacorsi, Stephane; Aschard, Hugues; Sokol, Harry; Cywes-Bentley, Colette; Mekalanos, John J.; Guillard, Thomas; Pier, Gerald B.; Roux, Damien; Skurnik, David

Synthetic peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections 形成纳米结构胶束的合成肽对多种微生物感染具有有效的抗生素和抗生物膜活性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-01-17

OAAI

Chou, Shuli; Guo, Huating; Zingl, Franz G.; Zhang, Shiqing; Toska, Jonida; Xu, Bocheng; Chen, Yili; Chen, Peisong; Waldor, Matthew K.; Zhao, Wenjing; Mekalanos, John J.; Mou, Xiangyu

Intratumoral injection of schwannoma with attenuated Salmonella typhimurium induces antitumor immunity and controls tumor growth 减毒鼠伤寒沙门氏菌瘤内注射神经鞘瘤诱导抗肿瘤免疫并控制肿瘤生长

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-06-08

OAAI

Ahmed, Sherif G.; Oliva, Giulia; Shao, Manlin; Wang, Xinhui; Mekalanos, John J.; Brenner, Gary J.

A Potent Inhibitor of the Cystic Fibrosis Transmembrane Conductance Regulator Blocks Disease and Morbidity Due to Toxigenic Vibrio cholerae

TOXINS

IF4

2022-03-18

OAAI

Rivera-Chavez, Fabian; Meader, Bradley T.; Akosman, Sinan; Koprivica, Vuk; Mekalanos, John J.

Sensing of intracellular Hcp levels controls T6SS expression in Vibrio cholerae 检测细胞内Hcp水平控制霍乱弧菌中T6SS的表达

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-06-14

OAAI

Manera, Kevin; Caro, Florence; Li, Hao; Pei, Tong-Tong; Hersch, Steven J.; Mekalanos, John J.; Dong, Tao G.

Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-28

OAAI

Stolle, Anne-Sophie; Meader, Bradley Thomas; Toska, Jonida; Mekalanos, John J.

Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes

MBIO

IF4.7

2020-12-22

OAAI

Caro, Florence; Caro, Jose A.; Place, Nicole M.; Mekalanos, John J.

Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling 细胞外环状二核苷酸通过腺苷信号诱导屏障上皮细胞的极化反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-10-21

OAAI

Chang, Denis; Whiteley, Aaron T.; Gwilt, Katlynn Bugda; Lencer, Wayne, I; Mekalanos, John J.; Thiagarajah, Jay R.

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity

MOLECULAR CELL

IF16.6

2020-02-01

140

OAAI

Lau, Rebecca K.; Ye, Qiaozhen; Birkholz, Erica A.; Berg, Kyle R.; Patel, Lucas; Mathews, Ian T.; Watrous, Jeramie D.; Ego, Kaori; Whiteley, Aaron T.; Lowey, Brianna; Mekalanos, John J.; Kranzusch, Philip J.; Jain, Mohit; Pogliano, Joe; Corbett, Kevin D.

A phase 1 randomized safety, reactogenicity, and immunogenicity study of Typhax: A novel protein capsular matrix vaccine candidate for the prevention of typhoid fever

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2020-01-06

OAAI

Cartee, Robert T.; Thanawastien, Ann; Griffin, Thomas J.; Mekalanos, John J.; Bart, Stephan; Killeen, Kevin P.

An onboard checking mechanism ensures effector delivery of the type VI secretion system in Vibrio cholerae

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-10-28

OAAI

Liang, Xiaoye; Kamal, Fatima; Pei, Tong-Tong; Xu, Ping; Mekalanos, John J.; Dong, Tao G.

Long-term Persistence of an Extensively Drug-Resistant Subclade of Globally Distributed Pseudomonas aeruginosa Clonal Complex 446 in an Academic Medical Center

CLINICAL INFECTIOUS DISEASES

IF7.3

2019-10-04

OAAI

Pincus, Nathan B.; Bachta, Kelly E. R.; Ozer, Egon A.; Allen, Jonathan P.; Pura, Olivia N.; Qi, Chao; Rhodes, Nathaniel J.; Marty, Francisco M.; Pandit, Alisha; Mekalanos, John J.; Oliver, Antonio; Hauser, Alan R.

Analysis of lipoprotein transport depletion in Vibrio cholerae using CRISPRi

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-08-01

OAAI

Caro, Florence; Place, Nicole M.; Mekalanos, John J.

In vitro characterization and preclinical immunogenicity of Typhax, a typhoid fever protein capsular matrix vaccine candidate

HUMAN VACCINES & IMMUNOTHERAPEUTICS

IF3.5

2019-05-28

OAAI

Griffin, Thomas J.; Thanawastien, Ann; Cartee, Robert T.; Mekalanos, John J.; Killeen, Kevin P.