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收藏Intranasal delivery of metformin using metal-organic framework (MOF)-74-Mg nanocarriers使用金属有机框架(MOF)-74-Mg纳米载体进行二甲双胍的鼻内递送
Yuan, MZZ; Han, ZS; Somayaji, Y; Nguyen, N; Hu, HW; Madhu, LN; Attaluri, S; Kodali, M; Yang, YH; Hsu, YC; Ahuja, A; Srinivasan, R; Pellois, JP; Zhou, HC; Shetty, AK; Wang, Y
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收藏Residual microglia following short-term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy
Kodali, Maheedhar; Madhu, Leelavathi N.; Somayaji, Yogish; Attaluri, Sahithi; Huard, Charles; Panda, Prashanta Kumar; Shankar, Goutham; Rao, Shama; Shuai, Bing; Gonzalez, Jenny J.; Oake, Chris; Hering, Catherine; Babu, Roshni Sara; Kotian, Sanya; Shetty, Ashok K.
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收藏Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease
Madhu, Leelavathi N.; Kodali, Maheedhar; Upadhya, Raghavendra; Rao, Shama; Somayaji, Yogish; Attaluri, Sahithi; Shuai, Bing; Kirmani, Maha; Gupta, Shreyan; Maness, Nathaniel; Rao, Xiaolan; Cai, James J.; Shetty, Ashok K.
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收藏FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Kodali, Maheedhar; Madhu, Leelavathi N.; Kolla, Venkata Sai Vashishta; Attaluri, Sahithi; Huard, Charles; Somayaji, Yogish; Shuai, Bing; Jordan, Chase; Rao, Xiaolan; Shetty, Sanath; Shetty, Ashok K.
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收藏Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus
Ayyubova, Gunel; Kodali, Maheedhar; Upadhya, Raghavendra; Madhu, Leelavathi N.; Attaluri, Sahithi; Somayaji, Yogish; Shuai, Bing; Rao, Shama; Shankar, Goutham; Shetty, Ashok K.
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收藏Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice
Attaluri, Sahithi; Gonzalez, Jenny Jaimes; Kirmani, Maha; Vogel, Andrew D.; Upadhya, Raghavendra; Kodali, Maheedhar; Madhu, Leelavathi N.; Rao, Shama; Shuai, Bing; Babu, Roshni S.; Huard, Charles; Shetty, Ashok K.
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收藏A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling
Kodali, Maheedhar; Madhu, Leelavathi N.; Reger, Roxanne L.; Milutinovic, Bojana; Upadhya, Raghavendra; Attaluri, Sahithi; Shuai, Bing; Shankar, Goutham; Shetty, Ashok K.
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收藏Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction鼻内给药的人MSC衍生的细胞外囊泡可抑制TBI后的NLRP3-p38/MAPK信号传导并预防慢性脑功能障碍
Kodali, Maheedhar; Madhu, Leelavathi N.; Reger, Roxanne L.; Milutinovic, Bojana; Upadhya, Raghavendra; Gonzalez, Jenny J.; Attaluri, Sahithi; Shuai, Bing; Gitai, Daniel L. G.; Rao, Shama; Choi, Jong M.; Jung, Sung Y.; Shetty, Ashok K.
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收藏Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression
Attaluri, Sahithi; Arora, Meenakshi; Madhu, Leelavathi N.; Kodali, Maheedhar; Shuai, Bing; Melissari, Laila; Upadhya, Raghavendra; Rao, Xiaolan; Bates, Adrian; Mitra, Eeshika; Ghahfarouki, Keyhan R.; Ravikumar, M. N., V; Shetty, Ashok K.
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收藏Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties
Upadhya, Raghavendra; Madhu, Leelavathi N.; Attaluri, Sahithi; Goes Gitai, Daniel Leite; Pinson, Marisa R.; Kodali, Maheedhar; Shetty, Geetha; Zanirati, Gabriele; Kumar, Smrithi; Shuai, Bing; Weintraub, Susan T.; Shetty, Ashok K.
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收藏A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology
Upadhya, Dinesh; Kodali, Maheedhar; Gitai, Daniel; Castro, Olagide W.; Zanirati, Gabriele; Upadhya, Raghavendra; Attaluri, Sahithi; Mitra, Eeshika; Shuai, Bing; Hattiangady, Bharathi; Shetty, Ashok K.
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收藏Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus
Hussain, Tabish; Kil, Hyunsuk; Hattiangady, Bharathi; Lee, Jaeho; Kodali, Maheedhar; Shuai, Bing; Attaluri, Sahithi; Takata, Yoko; Shen, Jianjun; Abba, Martin C.; Shetty, Ashok K.; Aldaz, C. Marcelo
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