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POINTER: study protocol for a phase 2b, randomised, placebo-controlled, double-blind, parallel group dose-finding clinical study to evaluate the efficacy of RMC-035 on renal function and safety, in participants at high risk for kidney injury, following open-chest cardiac surgery Zarbock, Alexander; Strauss, Christian; Laflamme, Maxime; Myjavec, Andrej; Boehm, Johannes; Burkert, Jan; Mazer, C. David; de Varennes, Benoit; Ginel Iglesias, Antonino; Matschke, Klaus; Larsson, Tobias E.; Reusch, Michael 分享 收藏
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Vascular regenerative deficiencies in people with elevated lipoprotein(a): the Lp(a)-VRCE CardioLink-16 translational study 脂蛋白(a)水平升高人群中的血管再生缺陷:Lp(a)-VRCE CardioLink-16转化研究 Moroney, Michael; Casey, Jack H.; Teoh, Hwee; Krishnaraj, Aishwarya; Pan, Yi; Quan, Adrian; Patel, Shubh K.; Dennis, Fallon; He, Arianna Z.; Park, Brady; Verma, Raj; Misner, Elizabeth; Seguchi, Ryuta; Hassan, Syed M. Ali; Dennis, Cole J.; Meglis, Gus; Pandey, Ambarish; Butler, Javed; Mazer, Cyril David; Byrne, Robert A.; Koschinsky, Marlys L.; Hess, David A.; Verma, Subodh 分享 收藏
Semaglutide promotes bone marrow-derived progenitor cell flux towards an anti-inflammatory and pro-regenerative profile in high-risk patients: the SEMA-VR CardioLink-15 trial 司美格鲁肽促进高风险患者骨髓源性祖细胞向抗炎和促修复表型的流动:SEMA-VR CardioLink-15试验 Park, Brady; Dennis, Fallon; He, Arianna Z.; Krishnaraj, Aishwarya; Bakbak, Ehab; Dennis, Cole J.; Pan, Yi; Misner, Elizabeth; Thayanithy, Veena; Lambotharan, Bhavaani; Lambotharan, Vaasudevan; Lambotharan, Aruna; Mazer, C. David; Quan, Adrian; Teoh, Hwee; Hess, David A.; Verma, Subodh 分享 收藏
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Benzodiazepine-Free Cardiac Anesthesia for Reduction of Postoperative Delirium: A Cluster Randomized Crossover Trial 苯二氮䓬类药物免用心脏麻醉以减少术后谵妄:一项集群随机交叉试验 Spence, Jessica; Devereaux, P. J.; Lee, Shun-Fu; D'Aragon, Frederick; Avidan, Michael S.; Whitlock, Richard P.; Mazer, C. David; Rousseau-Saine, Nicolas; Rajamohan, Raja Ramaswamy; Pryor, Kane O.; Klein, Rael; Tan, Edmund; Cameron, Matthew J.; Di Sante, Emily; Deborba, Erin; Mustard, Mary E.; Couture, Etienne J.; Zamper, Raffael Pereira Cezar; Law, Michael W. Y.; Djaiani, George; Saha, Tarit; Choi, Stephen; Hedlin, Peter; Pikaluk, D. Ryan; Lam, Wing; Deschamps, Alain; Ramasundarahettige, Chinthanie F.; Vincent, Jessica; Mcintyre, William F.; Oczkowski, Simon J. W.; Dulong, Braden J.; Beaver, Christopher; Kloppenburg, Shelley A.; Lamy, Andre; Jacobsohn, Eric; Belley-Cote, Emilie P.; B-Free Investigators; Canadian Perioperative Anesthesia Clinical Trials Grp 分享 收藏
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Response to Exploring the persistent questions regarding the long-term influence of bariatric surgery on psoriasis Mistry, Nikhil; Mazer, C. David; Sivaswamy, Atul; Haldenby, Olivia; Austin, Peter C.; Sud, Maneesh; Hare, Gregory M. T.; Shehata, Nadine; Ladha, Karim S.; Wijeysundera, Duminda N.; Verma, Subodh; Ko, Dennis T. 分享 收藏
Prognostic Value of NT-proBNP and the H2FPEF Score on Empagliflozin-associated Left Ventricular Remodeling: Insights from the EMPAHEART and EMPA-HEART 2 CardioLink Trial NT-proBNP和H2FPEF评分对恩格列净相关左心室重塑的预测价值:来自EMPAHEART和EMPA-HEART 2 CardioLink试验的见解 Hibino, Makoto; Verma, Subodh; Quan, Adrian; Puar, Pankaj; Akhavein, Farhad; Wang, Chao-Hung; Yan, Andrew; Connelly, Kim; Mazer, David; Teoh, Hwee 分享 收藏
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Efficacy and safety of therapeutic alpha-1-microglobulin RMC-035 in reducing kidney injury after cardiac surgery: a multicentre, randomised, double-blind, parallel group, phase 2a trial 治疗性alpha-1-microglobulin RMC-035减少心脏手术后肾损伤的有效性和安全性: 一项多中心、随机、双盲、平行组、2a期试验 Zarbock, Alexander; Larsson, Tobias E.; Noiseux, Nicolas; Mazer, C. David; Boehm, Johannes; Laflamme, Maxime; Matschke, Klaus; Burkert, Jan; de Varennes, Benoit; Myjavec, Andrej; Boening, Andreas; Koyner, Jay L.; Engelman, Dan; Reusch, Michael; Thielmann, Matthias 分享 收藏
Empagliflozin and left atrial function in patients with type 2 diabetes mellitus and coronary artery disease: insight from the EMPA-HEART CardioLink-6 randomized clinical trial Pourafkari, Marina; Connelly, Kim A.; Verma, Subodh; Mazer, C. David; Teoh, Hwee; Quan, Adrian; Goodman, Shaun G.; Rai, Archana; Ng, Ming Yen; Deva, Djeven P.; Triverio, Piero; Jiminez-Juan, Laura; Yan, Andrew T.; Ge, Yin 分享 收藏
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Patient Reported Outcome Measures in Adults with Fontan Circulatory Failure 患者报告的成人Fontan循环衰竭的预后指标 Agorrody, Guillermo; Begun, Isaac; Verma, Subodh; Mazer, C. David; Garagiola, Maria Luz; Fernandez-Campos, Beatriz; Acuna, Ronald; Kearney, Katherine; Buckley, Alvan; Dhingra, Nitish K.; Ghamarian, Ehsan; Roche, S. Lucy; Alonso-Gonzalez, Rafael; Wald, Rachel M. 分享 收藏
Icosapent ethyl modulates circulating vascular regenerative cell content: The IPE-PREVENTION CardioLink-14 trial Bakbak, Ehab; Krishnaraj, Aishwarya; Bhatt, Deepak L.; Quan, Adrian; Park, Brady; Bakbak, Asaad I.; Bari, Basel; Terenzi, Kristin A.; Pan, Yi; Fry, Elizabeth J.; Terenzi, Daniella C.; Puar, Pankaj; Khan, Tayyab S.; Rotstein, Ori D.; Mazer, C. David; Leiter, Lawrence A.; Teoh, Hwee; Hess, David A.; Verma, Subodh 分享 收藏