未登录.png)
分享.png)
收藏Selective Synergy of the Combination of Recombinant Methioninase With Cisplatinum and Ivermectin Which Eradicates Lung-Cancer Cells but Has No Synergy and Limited Effect on Normal Fibroblasts重组蛋氨酸酶与顺铂和伊维菌素组合的选择性协同作用，能够清除肺癌细胞，但对正常成纤维细胞无协同作用且效果有限。
Asano, Yohei; Han, Qinghong; Li, Shukuan; Mizuta, Kohei; Kang, Byung Mo; Kim, Jin Soo; Miyashi, Yuta; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Higuchi, Takashi; Morinaga, Sei; Tsuchiya, Hiroyuki; Demura, Satoru; Hoffman, Robert M. 分享 收藏 Triple Combination of Recombinant Methioninase and the Anti-parasitic Drugs Ivermectin, and Chloroquine Selectively Eradicates Pancreatic Cancer Cells While Sparing Normal FibroblastsAsano Y，Han Q，Li S，Mizuta K，Kang BM，Kim JS，等。重组甲硫氨酸酶与抗寄生虫药物伊维菌素和氯喹的三联组合可选择性清除胰腺癌细胞，同时保护正常成纤维细胞。Anticancer Res. (2025) 45:4791–802. doi: 10.21873/anticanres.17828Asano, Yohei; Han, Qinghong; Li, Shukuan; Mizuta, Kohei; Kang, Byung Mo; Kim, Jin Soo; Miyashi, Yuta; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Higuchi, Takashi; Morinaga, Sei; Tsuchiya, Hiroyuki; Demura, Satoru; Hoffman, Robert M. 分享 收藏 Very Rapid Eradication of a Large Squamous-Cell Carcinoma of the Head and Neck Treated With First-line Combination Chemotherapy, a Low-methionine Diet, and Oral Recombinant MethioninaseAsano, Yohei; Han, Qinghong; Li, Shukuan; Mizuta, Kohei; Kang, Byung Mo; Kim, Jin Soo; Miyashi, Yuta; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Higuchi, Takashi; Morinaga, Sei; Tsuchiya, Hiroyuki; Demura, Satoru; Hoffman, Robert M. 分享 收藏 A phase II study of irinotecan-cisplatin plus durvalumab for untreated extensive-stage small cell lung cancer (WJOG13520L, REBORN trial)伊立替康-顺铂联合度伐利尤单抗治疗初治广泛期小细胞肺癌的II期研究（WJOG13520L，REBORN试验）Tachihara, M.; Shoda, H.; Akazawa, Y.; Ota, T.; Oki, M.; Sato, Y.; Sugawara, S.; Ikeda, S.; Yokoyama, T.; Kaneda, H.; Itoh, S.; Bessho, A.; Katakami, N.; Morita, S.; Nakagawa, K.; Okamoto, I.; Yamamoto, N. 分享 收藏 Correlation between intratumor HER2 heterogeneity and circulating tumor DNA in HER2 positive advanced gastric cancer: A phase Ib trial of HER2 and PD-1 dual targeted therapy (Ni-High) substudyHER2阳性晚期胃癌中肿瘤内HER2异质性与循环肿瘤DNA的相关性：HER2和PD-1双靶向治疗（Ni-High） Ib期试验的子研究Osumi, H.; Wakatsuki, T.; Yamamoto, N.; Ooki, A.; Chin, K.; Shoji, H.; Ogura, M.; Nakayama, I.; Hirano, H.; Hara, H.; Minashi, K.; Shinozaki, E.; Kato, K.; Kitano, S.; Takeuchi, K.; Boku, N.; Yamaguchi, K.; Takahari, D. 分享 收藏 Second OS interim analysis from BEAT-SC: A randomized phase III study of bevacizumab (bev) or placebo in combination with atezolizumab and platinum-based chemotherapy in patients with extensive-stage small cell lung cancer (ES-SCLC)BEAT-SC研究的第二次操作系统中期分析：一项在广泛期小细胞肺癌（ES-SCLC）患者中，比较贝伐珠单抗（bev）或安慰剂联合阿替利珠单抗和铂类为基础的化疗的随机III期研究Han, B.; Ohe, Y.; Nishio, M.; Watanabe, S.; Ren, X.; Murakami, S.; Yang, N.; Okamoto, I.; Li, G.; Katakami, N.; Liu, X.; Hamaguchi, N.; Nakagawa, Y.; Hayashi, M.; Nanki, T.; Qian, C.; Yamamoto, N. 分享 收藏 分享 收藏 分享 收藏 Impact of sarcopenia on the outcome of patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy followed by durvalumabTamura, K.; Horinouchi, H.; Miyake, M.; Masuda, K.; Shinno, Y.; Okuma, Y.; Yoshida, T.; Goto, Y.; Yamamoto, N.; Ohe, Y. 分享 收藏 Clinical relevance of circulating tumor DNA in HER2-positive advanced gastric cancer: Results from phase Ib trial of HER2 and PD-1 dual targeted therapy (Ni-High)Osumi, H.; Wakatsuki, T.; Takahari, D.; Ooki, A.; Chin, K.; Shoji, H.; Ogura, M.; Nakayama, I.; Yamamoto, N.; Hirano, H.; Hara, H.; Minashi, K.; Shinozaki, E.; Kato, K.; Kurihara, N.; Kitano, S.; Takeuchi, K.; Boku, N.; Yamaguchi, K. 分享 收藏 Beamion Lung 1, an ongoing phase Ia/Ib trial of the HER2 TKI, BI 1810631 in patients (pts) with advanced solid tumors with HER2 aberrations: Latest dataOpdam, F.; Heymach, J.; Ruiter, G.; Barve, M.; Tu, H.; Wu, Y-L.; Schroeter, L.; Sadrolhefazi, B.; Serra, J.; Yoh, K.; Yamamoto, N. 分享 收藏 Clinical Impact of ERBB2 copy number and tumor mutation burden (TMB) in patients with HER2-positive advanced gastric cancer treated by nivolumab (N-mab) plus trastuzumab (T-mab) and standard chemotherapyShoji, H.; Wakatsuki, T.; Takahari, D.; Yamamoto, N.; Ooki, A.; Chin, K.; Kurihara, N.; Kiyotani, K.; Mashima, T.; Ogura, M.; Nakayama, I.; Minashi, K.; Hara, H.; Shinozaki, E.; Ishizuka, N.; Kitano, S.; Seimiya, H.; Takeuchi, K.; Boku, N.; Yamaguchi, K. 分享 收藏 Association between the adverse events and serum concentrations of lorlatinib in patients with advanced ALKpositive lung cancerShimoda, Y.; Yoshida, T.; Makihara, R. A.; Torasawa, M.; Tateishi, A.; Matsumoto, Y.; Shinno, Y.; Okuma, Y.; Goto, Y.; Horinouchi, H.; Yamamoto, N.; Ohe, Y. 分享 收藏 Incidence, clinicopathological features, and clinical outcomes of low HER2 expressed, inoperable, advanced, or recurrent gastric/gastroesophageal junction adenocarcinoma低HER2表达、不能手术、晚期或复发性胃/胃食管交界处腺癌的发病率、临床病理特征和临床预后Nakayama, I.; Takahari, D.; Chin, K.; Wakatsuki, T.; Takamatsu, M.; Yamamoto, N.; Ogura, M.; Ooki, A.; Fukuda, K.; Osumi, H.; Fukuoka, S.; Shinozaki, E.; Yamaguchi, K. 分享 收藏 A nonsteroidal anti-inflammatory drug, zaltoprofen, inhibits the growth of extraskeletal chondrosarcoma cells by inducing PPARγ, p21, p27, and p53Higuchi, Takashi; Takeuchi, Akihiko; Munesue, Seiichi; Yamamoto, Norio; Hayashi, Katsuhiro; Harashima, Ai; Yamamoto, Yasuhiko; Tsuchiya, Hiroyuki 分享 收藏 A Viability Analysis of Tumor-Bearing Frozen Autograft for the Reconstruction After Resection of Malignant Bone Tumors Using 99mTc-MDP Scintigraphy使用99mTc-MDP闪烁显像术对恶性骨肿瘤切除后的冷冻自体肿瘤进行重建的可行性分析Araki, Yoshihiro; Yamamoto, Norio; Hayashi, Katsuhiro; Takeuchi, Akihiko; Miwa, Shinji; Igarashi, Kentaro; Higuchi, Takashi; Abe, Kensaku; Taniguchi, Yuta; Yonezawa, Hirotaka; Morinaga, Sei; Asano, Yohei; Nojima, Takayuki; Taki, Junichi; Tsuchiya, Hiroyuki 分享 收藏 Family cancer history and smoking habit associated with sarcoma in a Japanese population studyAraki, Yoshihiro; Yamamoto, Norio; Tanzawa, Yoshikazu; Higashi, Takahiro; Kuchiba, Aya; Hayashi, Katsuhiro; Takeuchi, Akihiko; Miwa, Shinji; Igarashi, Kentaro; Endo, Makoto; Kobayashi, Eisuke; Tsuchiya, Hiroyuki; Kawai, Akira 分享 收藏 Randomized placebo-controlled double-blind phase II study of zaltoprofen for patients with diffuse-type and unresectable localized tenosynovial giant cell tumors: The REALIZE studyTakeuchi, Akihiko; Endo, Makoto; Kawai, Akira; Nishida, Yoshihiro; Terauchi, Ryu; Matsumine, Akihiko; Aiba, Hisaki; Nakamura, Tomoki; Tandai, Susumu; Ozaki, Toshifumi; Hoshi, Manabu; Kayano, Daiki; Okuda, Miho; Yamamoto, Norio; Hayashi, Katsuhiro; Miwa, Shinji; Igarashi, Kentaro; Yoshimura, Kenichi; Nomura, Akihiro; Murayama, Toshinori; Tsuchiya, Hiroyuki 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png)
ANTICANCER RESEARCH.png)
