未登录 Phase 1 dose-escalation trial evaluating a group 2 influenza hemagglutinin stabilized stem nanoparticle vaccine Casazza, Joseph P.; Hofstetter, Amelia R.; Costner, Pamela J. M.; Holman, LaSonji A.; Hendel, Cynthia S.; Widge, Alicia T.; Wu, Richard L.; Whalen, William R.; Cunningham, Jennifer; Arthur, Anita; Wang, Xiaolin; Ola, Abidemi; Saunders, Jamie; Mendoza, Floreliz; Novik, Laura; Burgos Florez, Maria C.; Ortega-Villa, Ana M.; Apte, Preeti J.; Strom, Larisa; Wang, Lu; Imam, Marjaan; Basappa, Manjula; Naisan, Mursal; Castro, Mike; Trost, Jessica F.; Narpala, Sandeep R.; Vanderven, Hillary A.; Yamshchikov, Galina V.; Berkowitz, Nina M.; Gordon, Ingelise J.; Plummer, Sarah H.; Wycuff, Diane L.; Vazquez, Sandra; Gillespie, Rebecca A.; Creanga, Adrian; Adams, William C.; Carlton, Kevin; Gall, Jason G.; Mcdermott, Adrian B.; Serebryannyy, Leonid A.; Houser, Katherine V.; Koup, Richard A.; Graham, Barney S.; Ledgerwood, Julie E.; Mascola, John R.; Pierson, Theodore C.; Andrews, Sarah F.; Kanekiyo, Masaru; Dropulic, Lesia K. 分享 收藏
Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS Awan, Seemal F.; Pegu, Amarendra; Strom, Larisa; Carter, Cristina A.; Hendel, Cynthia S.; Holman, LaSonji A.; Costner, Pamela J.; Trofymenko, Olga; Dyer, Renunda; Gordon, Ingelise J.; Rothwell, Ro Shauna S.; Hickman, Somia P.; Conan-Cibotti, Michelle; Doria-Rose, Nicole A.; Lin, Bob C.; O'Connell, Sarah; Narpala, Sandeep R.; Almasri, Cassandra G.; Liu, Cuiping; Ko, Sungyoul; Kwon, Young D.; Namboodiri, Aryan M.; Pandey, Janardan P.; Arnold, Frank J.; Carlton, Kevin; Gall, Jason G.; Kwong, Peter D.; Capparelli, Edmund, V; Bailer, Robert T.; Mcdermott, Adrian B.; Chen, Grace L.; Koup, Richard A.; Mascola, John R.; Coates, Emily E.; Ledgerwood, Julie E.; Gaudinski, Martin R. 分享 收藏
Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials Happe, Myra; Hofstetter, Amelia R.; Wang, Jing; Yamshchikov, Galina V.; Holman, LaSonji A.; Novik, Laura; Strom, Larisa; Kiweewa, Francis; Wakabi, Salim; Millard, Monica; Kelley, Colleen F.; Kabbani, Sarah; Edupuganti, Srilatha; Beck, Allison; Kaltovich, Florence; Murray, Tamar; Tsukerman, Susanna; Carr, Derick; Ashman, Carl; Stanley, Daphne A.; Ploquin, Aurelie; Bailer, Robert T.; Schwartz, Richard; Cham, Fatim; Tindikahwa, Allan; Hu, Zonghui; Gordon, Ingelise J.; Rouphael, Nadine; Houser, Katherine V.; Coates, Emily E.; Graham, Barney S.; Koup, Richard A.; Mascola, John R.; Sullivan, Nancy J.; Robb, Merlin L.; Ake, Julie A.; Lyke, Kirsten E.; Mulligan, Mark J.; Ledgerwood, Julie E.; Kibuuka, Hannah; Casazza, Joseph P.; Chen, Grace L.; Enama, Mary E.; Gaudinski, Martin R.; Hendel, Cynthia Starr; Costner, Pamela J. M.; Larkin, Brenda; Mendoza, Floreliz; Sanders, Jamie; Whalen, William R.; Zephir, Kathryn L.; Straling, Judith; Decederfelt, Hope; Conan-Cibotti, Michelle; Stein, Judy; Pittman, Iris R.; Vasilenko, Olga; Dezure, Adam; Sitar, Sandra; Dropulic, Lesia K.; Plummer, Sarah H.; Nguyen, Thuy A.; Berkowitz, Nina M.; Greenberg, Nancy; Chrisley, Lisa; Billington, Melissa; Wang, Xiaolin; Becker, Joanna; Campbell, James D.; Chen, Wilbur H.; Kwon, Alyson; Dorsey, Brenda; Courneya, Jennifer; Komninou, Panagiota; Lee, Myounghee; Bower, Mary; Bailey, Charles A.; Nesheim, Wendy; Girmay, Tigisty; Xu, Jianguo; Ogilvie, Melinda; Sadowski, Joann; Osinski, Eileen; Lai, Lilin; Grimes, Vicki; Kamya, Moses R.; Michael, Nelson L.; Kajumba, Francis; Ananworanich, Jinantat; Mwesigwa, Betty; Kimbugne, Geofrey; Luzinda, Kenneth; Nakabuye, Immaculate; Mukyala, Maureen G.; Kabahubya, Mable; Nakibuuka, Lydia; Matovu, Robinah 分享 收藏
Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial Mwesigwa, Betty; Houser, Katherine, V; Hofstetter, Amelia R.; Ortega-Villa, Ana M.; Naluyima, Prossy; Kiweewa, Francis; Nakabuye, Immaculate; Yamshchikov, Galina, V; Andrews, Charla; O'Callahan, Mark; Strom, Larisa; Schech, Steven; Eller, Leigh Anne; Sondergaard, Erica L.; Scott, Paul T.; Amare, Mihret F.; Modjarrad, Kayvon; Wamala, Amir; Tindikahwa, Allan; Musingye, Ezra; Nanyondo, Jauhara; Gaudinski, Martin R.; Gordon, Ingelise J.; Holman, LaSonji A.; Saunders, Jamie G.; Costner, Pamela J. M.; Mendoza, Floreliz H.; Happe, Myra; Morgan, Patricia; Plummer, Sarah H.; Hickman, Somia P.; Vazquez, Sandra; Murray, Tamar; Cordon, Jamilet; Dulan, Caitlyn N. M.; Hunegnaw, Ruth; Basappa, Manjula; Padilla, Marcelino; Gajjala, Suprabhath R.; Swanson II, Phillip A.; Lin, Bob C.; Coates, Emily E.; Gall, Jason G.; McDermott, Adrian B.; Koup, Richard A.; Mascola, John R.; Ploquin, Aurelie; Sullivan, Nancy J.; Kibuuka, Hannah; Ake, Julie A.; Ledgerwood, Julie E. 分享 收藏
Low-dose intravenous and subcutaneous CIS43LS monoclonal antibody for protection against malaria (VRC 612 Part C): a phase 1, adaptive trial Lyke, Kirsten E.; Berry, Andrea A.; Mason, Kaitlin; Idris, Azza H.; O'Callahan, Mark; Happe, Myra; Strom, Larisa; Berkowitz, Nina M.; Guech, Mercy; Hu, Zonghui; Castro, Mike; Basappa, Manjula; Wang, Lu; Low, Kwang; Holman, LaSonji A.; Mendoza, Floreliz; Gordon, Ingelise J.; Plummer, Sarah H.; Trofymenko, Olga; Strauss, Kathleen S.; Joshi, Sudhaunshu; Shrestha, Biraj; Adams, Matthew; Chagas, Andrezza Campos; Murphy, Jittawadee R.; Stein, Judy; Hickman, Somia; McDougal, Andrew; Lin, Bob; Narpala, Sandeep R.; Vazquez, Sandra; Serebryannyy, Leonid; McDermott, Adrian; Gaudinski, Martin R.; Capparelli, Edmund, V; Coates, Emily E.; Wu, Richard L.; Ledgerwood, Julie E.; Dropulic, Lesia K.; Seder, Robert A. 分享 收藏
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans Andrews, Sarah F.; Cominsky, Lauren Y.; Shimberg, Geoffrey D.; Gillespie, Rebecca A.; Gorman, Jason; Raab, Julie E.; Brand, Joshua; Creanga, Adrian; Gajjala, Suprabhath R.; Narpala, Sandeep; Cheung, Crystal S. F.; Harris, Darcy R.; Zhou, Tongqing; Gordon, Ingelise; Holman, LaSonji; Mendoza, Floreliz; V. Houser, Katherine; Chen, Grace L.; Mascola, John R.; Graham, Barney S.; Kwong, Peter D.; Widge, Alicia; Dropulic, Lesia K.; Ledgerwood, Julia E.; Kanekiyo, Masaru; McDermott, Adrian B. 分享 收藏
An influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults Widge, Alicia T.; Hofstetter, Amelia R.; V. Houser, Katherine; Awan, Seemal F.; Chen, Grace L.; Florez, Maria C. Burgos; Berkowitz, Nina M.; Mendoza, Floreliz; Hendel, Cynthia S.; Holman, LaSonji A.; Gordon, Ingelise J.; Apte, Preeti; Liang, C. Jason; Gaudinski, Martin R.; Coates, Emily E.; Strom, Larisa; Wycuff, Diane; Vazquez, Sandra; Stein, Judy A.; Gall, Jason G.; Adams, William C.; Carlton, Kevin; Gillespie, Rebecca A.; Creanga, Adrian; Crank, Michelle C.; Andrews, Sarah F.; Castro, Mike; Serebryannyy, Leonid A.; Narpala, Sandeep R.; Hatcher, Christian; Lin, Bob C.; O'Connell, Sarah; Freyn, Alec W.; Rosado, Victoria C.; Nachbagauer, Raffael; Palese, Peter; Kanekiyo, Masaru; McDermott, Adrian B.; Koup, Richard A.; Dropulic, Lesia K.; Graham, Barney S.; Mascola, John R.; Ledgerwood, Julie E. 分享 收藏
Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial Hamer, Melinda J.; Houser, Katherine, V; Hofstetter, Amelia R.; Ortega-Villa, Ana M.; Lee, Christine; Preston, Anne; Augustine, Brooke; Andrews, Charla; Yamshchikov, Galina, V; Hickman, Somia; Schech, Steven; Hutter, Jack N.; Scott, Paul T.; Waterman, Paige E.; Amare, Mihret F.; Kioko, Victoria; Storme, Casey; Modjarrad, Kayvon; McCauley, Melanie D.; Robb, Merlin L.; Gaudinski, Martin R.; Gordon, Ingelise J.; Holman, LaSonji A.; Widge, Alicia T.; Strom, Larisa; Happe, Myra; Cox, Josephine H.; Vazquez, Sandra; Stanley, Daphne A.; Murray, Tamar; Dulan, Caitlyn N. M.; Hunegnaw, Ruth; Narpala, Sandeep R.; Swanson II, Phillip A.; Basappa, Manjula; Thillainathan, Jagada; Padilla, Marcelino; Flach, Britta; O'Connell, Sarah; Trofymenko, Olga; Morgan, Patricia; Coates, Emily E.; Gall, Jason G.; McDermott, Adrian B.; Koup, Richard A.; Mascola, John R.; Ploquin, Aurelie; Sullivan, Nancy J.; Ake, Julie A.; Ledgerwood, Julie E. 分享 收藏
Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones 初次暴露于SARS-CoV-2变体会引起收敛的表位特异性，免疫球蛋白V基因的使用和公共b细胞克隆 Lima, Noemia S.; Musayev, Maryam; Johnston, Timothy S.; Wagner, Danielle A.; Henry, Amy R.; Wang, Lingshu; Yang, Eun Sung; Zhang, Yi; Birungi, Kevina; Black, Walker P.; O'Dell, Sijy; Schmidt, Stephen D.; Moon, Damee; Lorang, Cynthia G.; Zhao, Bingchun; Chen, Man; Boswell, Kristin L.; Roberts-Torres, Jesmine; Davis, Rachel L.; Peyton, Lowrey; Narpala, Sandeep R.; O'Connell, Sarah; Serebryannyy, Leonid; Wang, Jennifer; Schrager, Alexander; Talana, Chloe Adrienna; Shimberg, Geoffrey; Leung, Kwanyee; Shi, Wei; Khashab, Rawan; Biber, Asaf; Zilberman, Tal; Rhein, Joshua; Vetter, Sara; Ahmed, Afeefa; Novik, Laura; Widge, Alicia; Gordon, Ingelise; Guech, Mercy; Teng, I-Ting; Phung, Emily; Ruckwardt, Tracy J.; Pegu, Amarendra; Misasi, John; Doria-Rose, Nicole A.; Gaudinski, Martin; Koup, Richard A.; Kwong, Peter D.; McDermott, Adrian B.; Amit, Sharon; Schacker, Timothy W.; Levy, Itzchak; Mascola, John R.; Sullivan, Nancy J.; Schramm, Chaim A.; Douek, Daniel C. 分享 收藏
Low-Dose Subcutaneous or Intravenous Monoclonal Antibody to Prevent Malaria Wu, R. L.; Idris, A. H.; Berkowitz, N. M.; Happe, M.; Gaudinski, M. R.; Buettner, C.; Strom, L.; Awan, S. F.; Holman, L. S. A.; Mendoza, F.; Gordon, I. J.; Hu, Z.; Chagas, A. Campos; Wang, L. T.; Pereira, L. Da Silva; Francica, J. R.; Kisalu, N. K.; Flynn, B. J.; Shi, W.; Kong, W-P; O'Connell, S.; Plummer, S. H.; Beck, Allison; McDermott, A.; Narpala, S. R.; Serebryannyy, L.; Castro, M.; Silva, R.; Imam, M.; Pittman, I; Hickman, S. P.; McDougal, A. J.; Lukoskie, A. E.; Murphy, J. R.; Gall, J. G.; Carlton, K.; Morgan, P.; Seo, E.; Stein, J. A.; Vazquez, S.; Telscher, S.; Capparelli, E., V; Coates, E. E.; Mascola, J. R.; Ledgerwood, J. E.; Dropulic, L. K.; Seder, R. A. 分享 收藏
Safety and immunogenicity of a trivalent virus-like particle vaccine against western, eastern, and Venezuelan equine encephalitis viruses: a phase 1, open-label, dose-escalation, randomised clinical trial br Coates, Emily E.; Edupuganti, Srilatha; Chen, Grace L.; Happe, Myra; Strom, Larisa; Widge, Alicia; Florez, Maria Burgos; Cox, Josephine H.; Gordon, Ingelise; Plummer, Sarah; Ola, Abidemi; Yamshchikov, Galina; Andrews, Charla; Curate -Ingram, Sharon; Morgan, Patricia; Nagar, Shashi; Collins, Matthew H.; Bray, Amy; Nguyen, Thuy; Stein, Judy; Case, Christopher L.; Kaltovich, Florence; Wycuff, Diane; Liang, Jason; Carlton, Kevin; Vazquez, Sandra; Mascola, John R.; Ledgerwood, Julie E. 分享 收藏
Safety and immunogenicity of an HIV-1 prefusion- stabilized envelope trimer (Trimer 4571) vaccine in healthy adults: A first-in-human open-label , randomized, dose-escalation, phase 1 clinical trial Houser, Katherine, V; Gaudinski, Martin R.; Happe, Myra; Narpala, Sandeep; Verardi, Raffaello; Sarfo, Edward K.; Corrigan, Angela R.; Wu, Richard; Rothwell, Ro Shauna; Novik, Laura; Hendel, Cynthia S.; Gordon, Ingelise J.; Berkowitz, Nina M.; Cartagena, Cora Trelles; Widge, Alicia T.; Coates, Emily E.; Strom, Larisa; Hickman, Somia; Conan-Cibotti, Michelle; Vazquez, Sandra; Trofymenko, Olga; Plummer, Sarah; Stein, Judy; Case, Christopher L.; Nason, Martha; Biju, Andrea; Parchment, Danealle K.; Changela, Anita; Cheng, Cheng; Duan, Hongying; Geng, Hui; Teng, I-Ting; Zhou, Tongqing; O'Connell, Sarah; Barry, Chris; Carlton, Kevin; Gall, Jason G.; Flach, Britta; Doria-Rose, Nicole A.; Graham, Barney S.; Koup, Richard A.; McDermott, Adrian B.; Mascola, John R.; Kwong, Peter D.; Ledgerwood, Julie E. 分享 收藏
Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial Casazza, Joseph P.; Cale, Evan M.; Narpala, Sandeep; Yamshchikov, Galina, V; Coates, Emily E.; Hendel, Cynthia S.; Novik, Laura; Holman, LaSonji A.; Widge, Alicia T.; Apte, Preeti; Gordon, Ingelise; Gaudinski, Martin R.; Conan-Cibotti, Michelle; Lin, Bob C.; Nason, Martha C.; Trofymenko, Olga; Telscher, Shinyi; Plummer, Sarah H.; Wycuff, Diane; Adams, William C.; Pandey, Janardan P.; McDermott, Adrian; Roederer, Mario; Sukienik, Avery N.; O'Dell, Sijy; Gall, Jason G.; Flach, Britta; Terry, Travis L.; Choe, Misook; Shi, Wei; Chen, Xuejun; Kaltovich, Florence; Saunders, Kevin O.; Stein, Judy A.; Doria-Rose, Nicole A.; Schwartz, Richard M.; Balazs, Alejandro B.; Baltimore, David; Nabel, Gary J.; Koup, Richard A.; Graham, Barney S.; Ledgerwood, Julie E.; Mascola, John R. 分享 收藏
Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial Houser, Katherine, V; Chen, Grace L.; Carter, Cristina; Crank, Michelle C.; Nguyen, Thuy A.; Florez, Maria Claudia Burgos; Berkowitz, Nina M.; Mendoza, Floreliz; Hendel, Cynthia Starr; Gordon, Ingelise J.; Coates, Emily E.; Vazquez, Sandra; Stein, Judy; Case, Christopher L.; Lawlor, Heather; Carlton, Kevin; Gaudinski, Martin R.; Strom, Larisa; Hofstetter, Amelia R.; Liang, C. Jason; Narpala, Sandeep; Hatcher, Christian; Gillespie, Rebecca A.; Creanga, Adrian; Kanekiyo, Masaru; Raab, Julie E.; Andrews, Sarah F.; Zhang, Yi; Yang, Eun Sung; Wang, Lingshu; Leung, Kwanyee; Kong, Wing-Pui; Freyn, Alec W.; Nachbagauer, Raffael; Palese, Peter; Bailer, Robert T.; McDermott, Adrian B.; Koup, Richard A.; Gall, Jason G.; Arnold, Frank; Mascola, John R.; Graham, Barney S.; Ledgerwood, Julie E. 分享 收藏
Safety, tolerability, and immunogenicity of the respiratory syncytial virus prefusion F subunit vaccine DS-Cav1: a phase 1, randomised, open-label, dose-escalation clinical trial Ruckwardt, Tracy J.; Morabito, Kaitlyn M.; Phung, Emily; Crank, Michelle C.; Costner, Pamela J.; Holman, LaSonji A.; Chang, Lauren A.; Hickman, Somia P.; Berkowitz, Nina M.; Gordon, Ingelise J.; Yamshchikov, Galina, V; Gaudinski, Martin R.; Lin, Bob; Bailer, Robert; Chen, Man; Ortega-Villa, Ana M.; Nguyen, Thuy; Kumar, Azad; Schwartz, Richard M.; Kueltzo, Lisa A.; Stein, Judith A.; Carlton, Kevin; Gall, Jason G.; Nason, Martha C.; Mascola, John R.; Chen, Grace; Graham, Barney S. 分享 收藏
Functional Profiling of Antibody Immune Repertoires in Convalescent Zika Virus Disease Patients Fahad, Ahmed S.; Timm, Morgan R.; Madan, Bharat; Burgomaster, Katherine E.; Dowd, Kimberly A.; Normandin, Erica; Gutierrez-Gonzalez, Matias F.; Pennington, Joseph M.; De Souza, Matheus Oliveira; Henry, Amy R.; Laboune, Farida; Wang, Lingshu; Ambrozak, David R.; Gordon, Ingelise J.; Douek, Daniel C.; Ledgerwood, Julie E.; Graham, Barney S.; Castilho, Leda R.; Pierson, Theodore C.; Mascola, John R.; DeKosky, Brandon J. 分享 收藏
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates Corbett, Kizzmekia S.; Flynn, Barbara; Foulds, Kathryn E.; Francica, Joseph R.; Boyoglu-Barnum, Seyhan; Werner, Anne P.; Flach, Britta; O'Connell, Sarah; Bock, Kevin W.; Minai, Mahnaz; Nagata, Bianca M.; Andersen, Hanne; Martinez, David R.; Noe, Amy T.; Douek, Naomi; Donaldson, Mitzi M.; Nji, Nadesh N.; Alvarado, Gabriela S.; Edwards, Darin K.; Flebbe, Dillon R.; Lamb, Evan; Doria-Rose, Nicole A.; Lin, Bob C.; Louder, Mark K.; O'Dell, Sijy; Schmidt, Stephen D.; Phung, Emily; Chang, Lauren A.; Yap, Christina; Todd, John-Paul M.; Pessaint, Laurent; Van Ry, Alex; Browne, Shanai; Greenhouse, Jack; Putman-Taylor, Tammy; Strasbaugh, Amanda; Campbell, Tracey-Ann; Cook, Anthony; Dodson, Alan; Steingrebe, Katelyn; Shi, Wei; Zhang, Yi; Abiona, Olubukola M.; Wang, Lingshu; Pegu, Amarendra; Yang, Eun Sung; Leung, Kwanyee; Zhou, Tongqing; Teng, I-Ting; Widge, Alicia; Gordon, Ingelise; Novik, Laura; Gillespie, Rebecca A.; Loomis, Rebecca J.; Moliva, Juan I.; Stewart-Jones, Guillaume; Himansu, Sunny; Kong, Wing-Pui; Nason, Martha C.; Morabito, Kaitlyn M.; Ruckwardt, Tracy J.; Ledgerwood, Julie E.; Gaudinski, Martin R.; Kwong, Peter D.; Mascola, John R.; Carfi, Andrea; Lewis, Mark G.; Baric, Ralph S.; McDermott, Adrian; Moore, Ian N.; Sullivan, Nancy J.; Roederer, Mario; Seder, Robert A.; Graham, Barney S. 分享 收藏
Effect of a Chikungunya Virus-Like Particle Vaccine on Safety and Tolerability Outcomes A Randomized Clinical Trial 基孔肯雅病毒样颗粒疫苗对安全性和耐受性结果的影响随机临床试验 Chen, Grace L.; Coates, Emily E.; Plummer, Sarah H.; Carter, Cristina A.; Berkowitz, Nina; Conan-Cibotti, Michelle; Cox, Josephine H.; Beck, Allison; O'Callahan, Mark; Andrews, Charla; Gordon, Ingelise J.; Larkin, Brenda; Lampley, Rebecca; Kaltovich, Florence; Gall, Jason; Carlton, Kevin; Mendy, Jason; Haney, Doug; May, Jeanine; Bray, Amy; Bailer, Robert T.; Dowd, Kimberly A.; Brockett, Brittanie; Gordon, David; Koup, Richard A.; Schwartz, Richard; Mascola, John R.; Graham, Barney S.; Pierson, Theodore C.; Donastorg, Yeycy; Rosario, Nicolas; Pape, Jean William; Hoen, Bruno; Cabie, Andre; Diaz, Clemente; Ledgerwood, Julie E. 分享 收藏
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