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Activation of lysosomal iron triggers ferroptosis in cancer 溶酶体铁的激活触发癌细胞的铁死亡 Caneque, Tatiana; Baron, Leeroy; Mueller, Sebastian; Carmona, Alanis; Colombeau, Ludovic; Versini, Antoine; Solier, Stephanie; Gaillet, Christine; Sindikubwabo, Fabien; Sampaio, Julio L.; Sabatier, Marie; Mishima, Eikan; Picard-Bernes, Armel; Syx, Laurene; Servant, Nicolas; Lombard, Berangere; Loew, Damarys; Zheng, Jiashuo; Proneth, Bettina; Thoidingjam, Leishemba K.; Grimaud, Laurence; Fraser, Cameron S.; Szylo, Krystina J.; Kazarian, Emma Der; Bonnet, Caroline; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe; Santofimia-Castano, Patricia; Estaras, Matias; Dusetti, Nelson; Iovanna, Juan Lucio; Cunha, Antonio Sa; Pittau, Gabriella; Hammel, Pascal; Tzanis, Dimitri; Bonvalot, Sylvie; Watson, Sarah; Upadhyay, Aditya; Pratt, Derek A.; Freitas, Florencio Porto; Angeli, Jose Pedro Friedmann; Stockwell, Brent R.; Conrad, Marcus; Ubellacker, Jessalyn M. 分享 收藏
Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer STAT3/Fanconi贫血通路轴的抑制与PARP抑制在乳腺癌中具有合成致死性 Rouault, Celia D.; Bansard, Lucile; Martinez-Balsalobre, Elena; Bonnet, Caroline; Wicinski, Julien; Lin, Shuheng; Colombeau, Ludovic; Debieu, Sylvain; Pinna, Guillaume; Vandamme, Marie; Machu, Margot; Rosnet, Olivier; Chevrier, Veronique; Popovici, Cornel; Sobol, Hagay; Castellano, Remy; Pasquier, Eddy; Guasch, Geraldine; Rodriguez, Raphael; Pannequin, Julie; Pascussi, Jean-Marc; Lachaud, Christophe; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe 分享 收藏
Ovarian Clear Cell Carcinoma: Prognostic And Predictive Factors. A Multicenter Retrospective Study 卵巢透明细胞癌:预后与预测因素。一项多中心回顾性研究 Rosso, Roberta; Turinetto, Margherita; Treilleux, Isabelle; Ouldbey, Yaelle; Penault-Llorca, Frederique; Genestie, Catherine; Croce, Sabrina; Devouassoux, Mojgan; Henno, Sebastien; Lefeuvre, Claudia; Vincent-Salomon, Anne; Charafe-Jauffret, Emmanuelle; Provensal, Magali; Belda, Marie-Aude Le Frere; Selle, Frederic; Meeus, Pierre; Chopin, Nicolas; Le Saux, Olivia; Ferraioli, Domenico; Ray-Coquard, Isabelle 分享 收藏
Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study 度伐利尤单抗和特瑞普利单抗与常规口服长春瑞滨联合治疗复发性晚期宫颈癌:一项开放标签的I/II期研究 Frenel, Jean-Sebastien; Mathiot, Laurent; Cropet, Claire; Borcoman, Edith; Hervieu, Alice; Coquan, Elodie; de la Motte Rouge, Thibault; Saada-Bouzid, Esma; Sabatier, Renaud; Lavaud, Pernelle; Jimenez, Marta; Legrand, Francois; Le Saux, Olivia; Charafe, Emmanuelle; Goncalves, Anthony 分享 收藏
Decoding the pathological and genomic profile of epithelial ovarian cancer Rejaibi, Rim; Guille, Arnaud; Manai, Maroua; Adelaide, Jose; Agavnian, Emilie; Jelassi, Aida; Doghri, Raoudha; Charafe-Jauffret, Emmanuelle; Bertucci, Francois; Manai, Mohamed; Mrad, Karima; Charfi, Lamia; Sabatier, Renaud 分享 收藏
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A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors Laisne, Marthe; Rodgers, Brianna; Benlamara, Sarah; Wicinski, Julien; Nicolas, Andre; Djerroudi, Lounes; Gupta, Nikhil; Ferry, Laure; Kirsh, Olivier; Daher, Diana; Philippe, Claude; Okada, Yuki; Charafe-Jauffret, Emmanuelle; Cristofari, Gael; Meseure, Didier; Vincent-Salomon, Anne; Ginestier, Christophe; Defossez, Pierre-Antoine 分享 收藏
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Experimental and spontaneous metastasis assays can result in divergence in clonal architecture Serrano, Antonin; Weber, Tom; Berthelet, Jean; El-Saafin, Farrah; Gadipally, Sreeja; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe; Mariadason, John M.; Oakes, Samantha R.; Britt, Kara; Naik, Shalin H.; Merino, Delphine 分享 收藏
MiR-662 is associated with metastatic relapse in early-stage breast cancer and promotes metastasis by stimulating cancer cell stemness MiR-662与早期乳腺癌的转移复发有关,并通过刺激癌细胞的干细胞来促进转移 Puppo, Margherita; Valluru, Manoj Kumar; Croset, Martine; Ceresa, Davide; Iuliani, Michele; Khan, Ashrin; Wicinski, Julien; Charafe-Jauffret, EmmACTanuelle; Ginestier, Christophe; Pantano, Francesco; Ottewell, Penelope Dawn; Clezardin, Philippe 分享 收藏
CD25high Effector Regulatory T Cells Hamper Responses to PD-1 Blockade in Triple-Negative Breast Cancer Fattori, Stephane; Le Roy, Aude; Houacine, Jemila; Robert, Lucie; Abes, Riad; Gorvel, Laurent; Granjeaud, Samuel; Rouviere, Marie-Sarah; Ben Amara, Amira; Boucherit, Nicolas; Tarpin, Carole; Pakradouni, Jihane; Charafe-Jauffret, Emmanuelle; Houvenaeghel, Gilles; Lambaudie, Eric; Bertucci, Francois; Rochigneux, Philippe; Goncalves, Anthony; Foussat, Arnaud; Chretien, Anne-Sophie; Olive, Daniel 分享 收藏
Selective depletion of regulatory T cells by ALD2510, a novel IL-2-sparing anti-CD25 antibody, synergizes with PD-1 blockade in breast and gynecologic cancers Fattori, Stephane; Le Roy, Aude; Houacine, Jemila; Robert, Lucie; Abes, Riad; Gorvel, Laurent; Granjeaud, Samuel; Rouviere, Marie-Sarah; Ben Amara, Amira; Boucherit, Nicolas; Tarpin, Carole; Pakradouni, Jihane; Charafe-Jauffret, Emmanuelle; Barrou, Julien; Houvenaeghel, Gilles; Lambaudie, Eric; Bertucci, Francois; Rochigneux, Philippe; Goncalves, Anthony; Foussat, Arnaud; Chretien, Anne-Sophie; Olive, Daniel 分享 收藏
Overcoming Resistance to Anti-Nectin-4 Antibody-Drug Conjugate 克服对Anti-Nectin-4抗体-药物偶联物的抗性 Cabaud, Olivier; Berger, Ludovic; Crompot, Emerence; Adelaide, Jose; Finetti, Pascal; Garnier, Severine; Guille, Arnaud; Carbuccia, Nadine; Farina, Anne; Agavnian, Emilie; Chaffanet, Max; Goncalves, Anthony; Charafe-Jauffret, Emmanuelle; Mamessier, Emilie; Birnbaum, Daniel; Bertucci, Francois; Lopez, Marc 分享 收藏
BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells Azzoni, Violette; Wicinski, Julien; Macario, Manon; Castagne, Martin; Finetti, Pascal; Ambrosova, Katerina; Rouault, Celia D.; Serge, Arnaud; Farina, Anne; Agavnian, Emilie; Coslet, Sergiu; Josselin, Emmanuelle; Guille, Arnaud; Adelaide, Jose; Zacharioudakis, Emmanouil; Castellano, Remy; Bertucci, Francois; Birnbaum, Daniel; Rodriguez, Raphael; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe 分享 收藏
TAKTIC: A prospective, multicentre, uncontrolled, phase IB/II study of LY2780301, a p70S6K/AKT inhibitor, in combination with weekly paclitaxel in HER2-negative advanced breast cancer patients TAKTIC: LY2780301 (一种p70S6K/AKT抑制剂) 联合每周紫杉醇治疗HER2-negative晚期乳腺癌患者的前瞻性、多中心、非对照、IB/II期研究 Vicier, Cecile; Sfumato, Patrick; Isambert, Nicolas; Dalenc, Florence; Robert, Marie; Levy, Christelle; Rezai, Keyvan; Provansal, Magali; Adelaide, Jose; Garnier, Severine; Guille, Arnaud; Carbuccia, Nadine; Popovici, Cornel; Charafe-Jauffret, Emmanuelle; Chaffanet, Max; Birnbaum, Daniel; Pakradouni, Jihane; Bertucci, Francois; Boher, Jean M.; Sabatier, Renaud; Goncalves, Anthony 分享 收藏
A stem cell population at the anorectal junction maintains homeostasis and participates in tissue regeneration Mitoyan, Loucine; Chevrier, Veronique; Hernandez-Vargas, Hector; Ollivier, Alexane; Homayed, Zeinab; Pannequin, Julie; Poizat, Flora; De Biasi-Cador, Cecile; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe; Guasch, Geraldine 分享 收藏
Phenotypic discordance between primary and metastatic breast cancer in the large-scale real-life multicenter French ESME cohort Grinda, Thomas; Joyon, Natacha; Lusque, Amelie; Lefevre, Sarah; Arnould, Laurent; Penault-Llorca, Frederique; Macgrogan, Gaetan; Treilleux, Isabelle; Vincent-Salomon, Anne; Haudebourg, Juliette; Maran-Gonzalez, Aurelie; Charafe-Jauffret, Emmanuelle; Courtinard, Coralie; Franchet, Camille; Verriele, Veronique; Brain, Etienne; Tas, Patrick; Blanc-Fournier, Cecile; Leroux, Agnes; Loussouarn, Delphine; Berghian, Anca; Brabencova, Eva; Ghnassia, Jean Pierre; Scoazec, Jean-Yves; Delaloge, Suzette; Filleron, Thomas; Lacroix-Triki, Magali 分享 收藏