Neil D. Perkins - Publications, H-index & Citations

Neil D. Perkins

newcastle university

61H指数

196论文数

1.7W被引数

收录论文 105

发表时间

Targeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha 通过选择性抑制IκB激酶α靶向CYLD皮肤综合征中的非经典NF-κB信号通路

British Journal of Dermatology

IF9.6

2026-03-04

OAAI

Kirsty Hodgson; Joseph Inns; Gary Reynolds; Emily Stephenson; Andrew Paul; Naomi Sinclair; Giacomo Berretta; Christopher Lawson; Andrew Michael Frey; Iglika Ivanova; Eva Adam; Christopher J Lord; Simon Cockell; Jonathan Coxhead; Nikoletta Nagy; David Adams; Marta Szell; Matthias Trost; Muzlifah Haniffa; Simon P Mackay; Neil Perkins; Neil Rajan; null

Defective anterograde protein-trafficking contributes to endoplasmic reticulum-stress in a CLN1 disease model 缺陷性顺向蛋白质转运导致CLN1疾病模型中内质网应激

NEUROBIOLOGY OF DISEASE

IF5.6

2025-06-01

OAAI

Plavelil, Nisha; Appu, Abhilash P.; Gopal, K. C.; Mondal, Avisek; Perkins, Neil; Mukherjee, Anil B.

Domain-specific AI segmentation of IMPDH2 rod/ring structures in mouse embryonic stem cells 特定领域AI对小鼠胚胎干细胞中IMPDH2杆/环状结构的分割

BMC BIOLOGY

IF4.5

2025-05-12

OAAI

Ball, Samuel T. M.; Hennessy, Meagan J.; Tan, Yuhan; Hoettges, Kai F.; Perkins, Neil D.; Wilkinson, David J.; White, Michael R. H.; Zheng, Yalin; Turner, David A.

The NEMO/ATM/IKKα complex: A key player in colorectal cancer progression and treatment NEMO/ATM/IKKα复合物：结直肠癌进展和治疗中的关键参与者

SCIENCE SIGNALING

IF6.6

2025-03-11

PREAI

Perkins, Neil D.

How can gene editing of human pluripotent stem cells help understand the effect of genetics on respiratory diseases?

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Ocana, Sara Cuevas; Yang, Jin Ye; Aushev, Magomet; Schlossmacher, George; Bear, Christine E.; Hannan, Nicholas R. F.; Perkins, Neil D.; Rossant, Janet; Wong, Amy P.; Gray, Michael A.

c-Rel-dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

HEPATOLOGY

IF15.8

2023-09-27

OAAI

Leslie, Jack; Hunter, Jill E.; Collins, Amy; Rushton, Amelia; Russell, Lauren G.; Ramon-Gil, Erik; Laszczewska, Maja; McCain, Misti; Zaki, Marco Y. W.; Knox, Amber; Seow, Yixin; Sabater, Laura; Geh, Daniel; Perkins, Neil D.; Reeves, Helen L.; Tiniakos, Dina; Mann, Derek A.; Oakley, Fiona

A novel transcriptional repression domain mediates p21WAF1/CIP1 induction of p300 transactivation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

140

OAAI

Snowden, AW; Anderson, LA; Webster, GA; Perkins, ND

Regulation of RelA (p65) function by the large subunit of replication factor C

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Anderson, LA; Perkins, ND

The ETS domain transcription factor Elk-1 contains a novel class of repression domain

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Yang, SH; Bumpass, DC; Perkins, ND; Sharrocks, AD

p53 Represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-κB subunit with histone deacetylase 1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

231

OAAI

Rocha, S; Martin, AM; Meek, DW; Perkins, ND

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

BIOCHEMICAL JOURNAL

IF4.3

2022-10-14

OAAI

Hunter, Jill E.; Campbell, Amy E.; Hannaway, Nicola L.; Kerridge, Scott; Luli, Saimir; Butterworth, Jacqueline A.; Sellier, Helene; Mukherjee, Reshmi; Dhillon, Nikita; Sudhindar, Praveen D.; Shukla, Ruchi; Brownridge, Philip J.; Bell, Hayden L.; Coxhead, Jonathan; Taylor, Leigh; Leary, Peter; Hasoon, Megan S. R.; Collins, Ian; Garrett, Michelle D.; Eyers, Claire E.; Perkins, Neil D.

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant E?-Myc lymphoma cells

BIOCHEMICAL JOURNAL

IF4.3

2022-10-14

OAAI

Hunter, Jill E.; Campbell, Amy E.; Kerridge, Scott; Fraser, Callum; Hannaway, Nicola L.; Luli, Saimir; Ivanova, Iglika; Brownridge, Philip J.; Coxhead, Jonathan; Taylor, Leigh; Leary, Peter; Hasoon, Megan S. R.; Eyers, Claire E.; Perkins, Neil D.

Claspin haploinsufficiency leads to defects in fertility, hyperplasia and an increased oncogenic potential

BIOCHEMICAL JOURNAL

IF4.3

2022-10-14

OAAI

Madgwick, Suzanne; Luli, Saimir; Sellier, Helene; Butterworth, Jacqueline A.; Leslie, Jack; Moore, Adam J.; Corbin, Emma K.; Yemm, Adrian I.; Chiremba, Robson T.; Tiniakos, Dina; Oakley, Fiona; Perkins, Neil D.; Hunter, Jill E.

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

BIOCHEMICAL JOURNAL

IF4.3

2022-10-14

OAAI

Hunter, Jill E.; Campbell, Amy E.; Butterworth, Jacqueline A.; Sellier, Helene; Hannaway, Nicola L.; Luli, Saimir; Floudas, Achilleas; Kenneth, Niall S.; Moore, Adam J.; Brownridge, Philip J.; Thomas, Huw D.; Coxhead, Jonathan; Taylor, Leigh; Leary, Peter; Hasoon, Megan S. R.; Knight, Andrew M.; Garrett, Michelle D.; Collins, Ian; Eyers, Claire E.; Perkins, Neil D.

The Catalytic Reactivity of Alloys; Ethanol and Formic Acid Decomposition on Cu-Pd(110)

JOURNAL OF PHYSICAL CHEMISTRY C

IF3.2

2022-09-12

OAAI

Bowker, Michael; Holroyd, Richard; Perkins, Neil

Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway

BIOCHEMICAL JOURNAL

IF4.3

2022-06-01

PREAI

Perkins, Neil D.

Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase

SCIENTIFIC REPORTS

IF3.9

2022-05-13

OAAI

Russell, Lauren G.; Davis, Lydia A. K.; Hunter, Jill E.; Perkins, Neil D.; Kenneth, Niall S.

Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12

COMMUNICATIONS BIOLOGY

IF5.1

2021-12-08

OAAI

Sandhu, Sumit; Sou, Ieng F.; Hunter, Jill E.; Salmon, Lucy; Wilson, Caroline L.; Perkins, Neil D.; Hunter, Neil; Davies, Owen R.; McClurg, Urszula L.

Temporal modulation of the NF-κB ReIA network in response to different types of DNA damage

BIOCHEMICAL JOURNAL

IF4.3

2021-02-10

OAAI

Campbell, Amy E.; Franco, Catarina Ferraz; Su, Ling-, I; Corbin, Emma K.; Perkins, Simon; Kalyuzhnyy, Anton; Jones, Andrew R.; Brownridge, Philip J.; Perkins, Neil D.; Eyers, Claire E.

Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis (vol 63, pg 916, 2020)

NATURE CANCER

IF28.5

2020-11-30

OAAI

Smith, Anna L. M.; Whitehall, Julia C.; Bradshaw, Carla; Gay, David; Robertson, Fiona; Blain, Alasdair P.; Hudson, Gavin; Pyle, Angela; Houghton, David; Hunt, Matthew; Sampson, James N.; Stamp, Craig; Mallett, Grace; Amarnath, Shoba; Leslie, Jack; Oakley, Fiona; Wilson, Laura; Baker, Angela; Russell, Oliver M.; Johnson, Riem; Richardson, Claire A.; Gupta, Bhavana; McCallum, Iain; McDonald, Stuart A. C.; Kelly, Seamus; Mathers, John C.; Heer, Rakesh; Taylor, Robert W.; Perkins, Neil D.; Turnbull, Doug M.; Sansom, Owen J.; Greaves, Laura C.

研究方向