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Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis B Yuen, Man-Fung; Berliba, Elina; Sukeepaisarnjaroen, Wattana; Ahn, Sang Hoon; Tanwandee, Tawesak; Lim, Young-Suk; Kim, Yoon Jun; Poovorawan, Kittiyod; Tangkijvanich, Pisit; Schwabe, Christian; Eley, Timothy; Brown, Joanne; Lee, Amy C. H.; Thi, Emily P.; Paratala, Bhavna; Mani, Nagraj; Sofia, Michael J.; Picchio, Gaston; Sims, Karen D.; Gane, Edward J. 分享 收藏
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Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin Fevery, Bart; Thys, Kim; Van Eygen, Veerle; Verbinnen, Thierry; Van Rossem, Elizabeth; Buelens, Annemie; Aerssens, Jeroen; Witek, James; Picchio, Gaston; De Meyer, Sandra; Lenz, Oliver 分享 收藏
Daclatasvir plus simeprevir with or without ribavirin for the treatment of chronic hepatitis C virus genotype 1 infection Zeuzem, Stefan; Hezode, Christophe; Bronowicki, Jean-Pierre; Loustaud-Ratti, Veronique; Gea, Francisco; Buti, Maria; Olveira, Antonio; Banyai, Tivadar; Al-Assi, M. Tarek; Petersen, Joerg; Thabut, Dominique; Gadano, Adrian; Pruitt, Ronald; Makara, Mihaly; Bourliere, Marc; Pol, Stanislas; Beumont-Mauviel, Maria; Ouwerkerk-Mahadevan, Sivi; Picchio, Gaston; Bifano, Marc; McPhee, Fiona; Boparai, Navdeep; Cheung, Kin; Hughes, Eric A.; Noviello, Stephanie 分享 收藏
Comparison of three quantitative HCV RNA assays in samples from HCV genotype 1-or 4-infected patients treated with the NS3/4A protease inhibitor simeprevir Fevery, Bart; Susser, Simone; Lenz, Oliver; Cloherty, Gavin; Perner, Dany; Gilles, Leen; De Locht, Patrick; Picchio, Gaston; De Meyer, Sandra; Sarrazin, Christoph 分享 收藏
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Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies Lenz, Oliver; Verbinnen, Thierry; Fevery, Bart; Tambuyzer, Lotke; Vijgen, Leen; Peeters, Monika; Buelens, Annemie; Ceulemans, Hugo; Beumont, Maria; Picchio, Gaston; De Meyer, Sandra 分享 收藏
SIMEPREVIR (SMV) PLUS DACLATASVIR (DCV) AND SOFOSBUVIR (SOF) IN TREATMENT-NAIVE AND -EXPERIENCED PATIENTS WITH CHRONIC HEPATITIS C VIRUS GENOTYPE 1 OR 4 INFECTION AND DECOMPENSATED LIVER DISEASE: INTERIM RESULTS FROM THE PHASE II IMPACT STUDY Lawitz, E.; Poordad, F.; Gutierrez, J.; Kakuda, T.; Picchio, G.; De La Rosa, G.; Beets, G.; Vandevoorde, A.; Van Remoortere, P.; Jacquemyn, B.; Quinn, G.; Luo, D.; Ouwerkerk-Mahadevan, S.; Vijgen, L.; Van Eygen, V.; Beumont, M. 分享 收藏
DEEP SEQUENCING ANALYSES IN HCV GENOTYPE 1-INFECTED PATIENTS TREATED WITH SIMEPREVIR PLUS SOFOSBUVIR WITH/WITHOUT RIBAVIRIN IN THE COSMOS STUDY Fevery, B.; Thys, K.; Van Rossem, E.; Verbinnen, T.; Picchio, G.; Aerssens, J.; De Meyer, S.; Beumont, M.; Kurland, D.; Lenz, O. 分享 收藏
An OPTIMIZE Study Retrospective Analysis for Management of Telaprevir-Treated Hepatitis C Virus (HCV)-Infected Patients by Use of the Abbott RealTime HCV RNA Assay Sarrazin, Christoph; Dierynck, Inge; Cloherty, Gavin; Ghys, Anne; Janssen, Katrien; Luo, Donghan; Witek, James; Buti, Maria; Picchio, Gaston; De Meyer, Sandra 分享 收藏
Low-density lipoprotein and other predictors of response with telaprevir-based therapy in treatment-experienced HCV genotype 1 patients: REALIZE study Berg, Thomas; Andreone, Pietro; Pol, Stanislas; Roberts, Stuart; Younossi, Zobair; Diago, Moises; Lawitz, Eric J.; Focaccia, Roberto; Foster, Graham R.; Horban, Andrzej; Lonjon-Domanec, Isabelle; DeMasi, Ralph; Picchio, Gaston; Luo, Donghan; De Meyer, Sandra; Zeuzem, Stefan 分享 收藏
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study Lawitz, Eric; Sulkowski, Mark S.; Ghalib, Reem; Rodriguez-Torres, Maribel; Younossi, Zobair M.; Corregidor, Ana; DeJesus, Edwin; Pearlman, Brian; Rabinovitz, Mordechai; Gitlin, Norman; Lim, Joseph K.; Pockros, Paul J.; Scott, John D.; Fevery, Bart; Lambrecht, Tom; Ouwerkerk-Mahadevan, Sivi; Callewaert, Katleen; Symonds, William T.; Picchio, Gaston; Lindsay, Karen L.; Beumont, Maria; Jacobson, Ira M. 分享 收藏
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SIMEPREVIR PLUS SOFOSBUVIR WITH/WITHOUT RIBAVIRIN IN HCV GENOTYPE 1 PRIOR NULL-RESPONDER/TREATMENT-NAIVE PATIENTS (COSMOS STUDY): PRIMARY ENDPOINT (SVR12) RESULTS IN PATIENTS WITH METAVIR F3-4 (COHORT 2) Lawitz, E.; Ghalib, R.; Rodriguez-Torres, M.; Younossi, Z. M.; Corregidor, A.; Sulkowski, M. S.; DeJesus, E.; Pearlman, B.; Rabinovitz, M.; Gitlin, N.; Lim, J. K.; Pockros, P. J.; Fevery, B.; Lambrecht, T.; Ouwerkerk-Mahadevan, S.; Callewaert, K.; Symonds, W. T.; Picchio, G.; Lindsay, K.; Beumont-Mauviel, M.; Jacobson, I. M. 分享 收藏
VIROLOGY ANALYSES OF SIMEPREVIR IN PHASE 2B AND 3 STUDIES Lenz, O.; Verbinnen, T.; Fevery, B.; Tambuyzer, L.; Vijgen, L.; Peeters, M.; Buelens, A.; Beumont-Mauviel, M.; Picchio, G.; de Meyer, S. 分享 收藏
ONCE-DAILY SIMEPREVIR (TMC435) PLUS SOFOSBUVIR (GS-7977) WITH OR WITHOUT RIBAVIRIN IN HCV GENOTYPE 1 PRIOR NULL RESPONDERS WITH METAVIR F0-2: COSMOS STUDY SUBGROUP ANALYSIS Sulkowski, M.; Jacobson, I. M.; Ghalib, R.; Rodriguez-Torres, M.; Younossi, Z.; Corregidor, A.; Fevery, B.; Callewaert, K.; Symonds, W.; De La Rosa, G.; Picchio, G.; Ouwerkerk-Mahadevan, S.; Lambrecht, T.; Lawitz, E. 分享 收藏
EVALUATION OF OPTIMAL HCVRNA CUT-OFFS WITH TWO MAJOR REAL-TIME PCR-BASED ASSAYS FOR RESPONSE-GUIDED TRIPLE THERAPY WITH TELAPREVIR Sarrazin, C.; Dierynck, I.; Cloherty, G.; Ghys, A.; Janssen, K.; Van Eygen, V.; Luo, D.; Witek, J.; Buti, M.; Picchio, G.; De Meyer, S. 分享 收藏
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