Joseph Avruch - Publications, H-index & Citations

Joseph Avruch

Harvard University

103H指数

262论文数

4.6W被引数

收录论文 76

发表时间

An intact Raf zinc finger is required for optimal binding to processed Ras and for Ras-dependent Raf activation in situ

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

120

OAAI

Luo, ZJ; Diaz, B; Marshall, MS; Avruch, J

Amino acid-induced translation of TOP mRNAs is fully dependent on phosphatidylinositol 3-kinase-mediated signaling, is partially inhibited by rapamycin and is independent of S6K1 and rpS6 phosphorylation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

313

OAAI

Tang, H; Hornstein, E; Stolovich, M; Levy, G; Livingstone, M; Templeton, D; Avruch, J; Meyuhas, O

A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Hagan, G. Nana; Lin, Yenshou; Magnuson, Mark A.; Avruch, Joseph; Czech, Michael P.

The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

128

OAAI

Patursky-Polischuk, Ilona; Stolovich-Rain, Miri; Hausner-Hanochi, Mirit; Kasir, Judith; Cybulski, Nadine; Avruch, Joseph; Rueegg, Markus A.; Hall, Michael N.; Meyuhas, Oded

IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-03

OAAI

Regue, Laura; Ji, Fei; Flicker, Daniel; Kramer, Dana; Pierce, William; Davidoff, Teekhon; Widrick, Jeffrey J.; Houstis, Nicholas; Minichiello, Liliana; Dai, Ning; Avruch, Joseph

Human T2D-Associated Gene IMP2/IGF2BP2 Promotes the Commitment of Mesenchymal Stem Cells Into Adipogenic Lineage

DIABETES

IF7.5

2022-10-11

OAAI

Regue, Laura; Wang, William; Ji, Fei; Avruch, Joseph; Wang, Hua; Dai, Ning

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression

MOLECULAR METABOLISM

IF6.6

2021-06-01

OAAI

Regue, Laura; Zhao, Liping; Ji, Fei; Wang, Hua; Avruch, Joseph; Dai, Ning

Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-08-01

OAAI

Regue, Laura; Minichiello, Liliana; Avruch, Joseph; Dai, Ning

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk 胰岛染色质的可及性和构象揭示了2型糖尿病风险的远端增强子网络

NATURE COMMUNICATIONS

IF15.7

2019-05-07

OAAI

Greenwald, William W.; Chiou, Joshua; Yan, Jian; Qiu, Yunjiang; Dai, Ning; Wang, Allen; Nariai, Naoki; Aylward, Anthony; Han, Jee Yun; Kadakia, Nikita; Regue, Laura; Okino, Mei-Lin; Drees, Frauke; Kramer, Dana; Vinckier, Nicholas; Minichiello, Liliana; Gorkin, David; Avruch, Joseph; Frazer, Kelly A.; Sander, Maike; Ren, Bing; Gaulton, Kyle J.

The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development Mst1激酶是滤泡b细胞归巢和B-1 b细胞发育所必需的

FRONTIERS IN IMMUNOLOGY

IF5.9

2018-10-17

OAAI

Alsufyani, Faisal; Mattoo, Hamid; Zhou, Dawang; Cariappa, Annaiah; Van Buren, Denille; Hock, Hanno; Avruch, Joseph; Pillai, Shiv

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

NATURE IMMUNOLOGY

IF27.6

2015-09-28

226

OAAI

Geng, Jing; Sun, Xiufeng; Wang, Ping; Zhang, Shihao; Wang, Xiaozhen; Wu, Hongtan; Hong, Lixin; Xie, Changchuan; Li, Xun; Zhao, Hao; Liu, Qingxu; Jiang, Mingting; Chen, Qinghua; Zhang, Jinjia; Li, Yang; Song, Siyang; Wang, Hong-Rui; Zhou, Rongbin; Johnson, Randy L.; Chien, Kun-Yi; Lin, Sheng-Cai; Han, Jiahuai; Avruch, Joseph; Chen, Lanfen; Zhou, Dawang

A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation

MOLECULAR CANCER THERAPEUTICS

IF5.5

2015-07-06

PREAI

Papageorgiou, Angela; Tamayo, Pablo; Mesirov, Jill; Avruch, Joseph; Rapley, Joseph

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression YAP抑制可恢复晚期HCC的肝细胞分化，导致肿瘤消退

CELL REPORTS

IF6.9

2015-03-01

202

OAAI

Fitamant, Julien; Kottakis, Filippos; Benhamouche, Samira; Tian, Helen S.; Chuvin, Nicolas; Parachoniak, Christine A.; Nagle, Julia M.; Perera, Rushika M.; Lapouge, Marjorie; Deshpande, Vikram; Zhu, Andrew X.; Lai, Albert; Min, Bosun; Hoshida, Yujin; Avruch, Joseph; Sia, Daniela; Camprecios, Genis; McClatchey, Andrea I.; Llovet, Josep M.; Morrissey, David; Raj, Lakshmi; Bardeesy, Nabeel

Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment

CELL DEATH & DISEASE

IF9.6

2014-05-29

OAAI

Matsumoto, H.; Murakami, Y.; Kataoka, K.; Lin, H.; Connor, K. M.; Miller, J. W.; Zhou, D.; Avruch, J.; Vavvas, D. G.

Amino Acids Activate Mammalian Target of Rapamycin (mTOR) Complex 1 without Changing Rag GTPase Guanyl Nucleotide Charging 氨基酸激活哺乳动物雷帕霉素靶蛋白 (mTOR) 复合物1，而不改变Rag GTPase鸟苷酸核苷酸电荷

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-01-01

OAAI

Oshiro, Noriko; Rapley, Joseph; Avruch, Joseph

BASIC AND TRANSLATIONAL-PANCREAS

GASTROENTEROLOGY

IF25.1

2013-06-01

133

OAAI

Gao, Tao; Zhou, Dawang; Yang, Chenghua; Singh, Tarjinder; Penzo-Mendez, Alfredo; Maddipati, Ravikanth; Tzatsos, Alexandros; Bardeesy, Nabeel; Avruch, Joseph; Stanger, Ben Z.

The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense

CELL REPORTS

IF6.9

2013-05-01

121

OAAI

Wu, Hongtan; Xiao, Yubo; Zhang, Shihao; Ji, Suyuan; Wei, Luyao; Fan, Fuqin; Geng, Jing; Tian, Jing; Sun, Xiufeng; Qin, Funiu; Jin, Changnan; Lin, Jianjun; Yin, Zhen-Yu; Zhang, Ting; Luo, Lianzhong; Li, Yang; Song, Siyang; Lin, Sheng-Cai; Deng, Xianming; Camargo, Fernando; Avruch, Joseph; Chen, Lanfen; Zhou, Dawang

G protein-coupled receptors engage the mammalian Hippo pathway through F-actin F-Actin, assembled in response to Galpha12/13 induced RhoA-GTP, promotes dephosphorylation and activation of the YAP oncogene

BIOESSAYS

IF2.7

2013-03-01

OAAI

Regue, Laura; Mou, Fan; Avruch, Joseph

Protein kinases of the Hippo pathway: Regulation and substrates Hippo途径的蛋白激酶: 调控和底物

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

IF6

2012-09-01

218

OAAI