Erdal Toprak - Publications, H-index & Citations

Erdal Toprak

The University of Texas Southwestern Medical Center

21H指数

74论文数

3.2K被引数

收录论文 25

发表时间

Higher-order epistasis drives evolutionary unpredictability toward new antibiotic resistance 高阶表型相互作用驱动向新抗生素抗性进化的不可预测性

Nature Communications

IF15.7

2026-09-04

OAAI

Ilona Kamila Gaszek; Muhammed Sadik Yildiz; Zhaoxu Meng; Jose Alberto de la Paz; Sophia Maria Alvarez; Deniz Sezer; Faruck Morcos; Milo Lin; Erdal Toprak

A simple; low-cost; and highly efficient protocol for rapid isolation of pathogenic bacteria from human blood 一种简单、低成本且高效的快速从人血中分离病原细菌的方案

Frontiers in Microbiology

IF4.5

2025-08-13

OAAI

Fatma S. Coskun; Joshua Quick; Erdal Toprak

Structural shifts in TolC facilitate Efflux-Mediated β-lactam resistance

COMMUNICATIONS BIOLOGY

IF5.1

2024-08-26

OAAI

Kantarcioglu, Isik; Gaszek, Ilona K.; Guclu, Tandac F.; Yildiz, M. Sadik; Atilgan, Ali Rana; Toprak, Erdal; Atilgan, Canan

Kinetic Barrier to Enzyme Inhibition Is Manipulated by Dynamical Local Interactions in E. coli DHFR

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-07-26

OAAI

Cetin, Ebru; Guclu, Tandac F.; Kantarcioglu, Isik; Gaszek, Ilona K.; Toprak, Erdal; Atilgan, Ali Rana; Dedeoglu, Burcu; Atilgan, Canan

The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2021-06-27

OAAI

Tamer, Yusuf Talha; Gaszek, Ilona; Rodrigues, Marinelle; Coskun, Fatma Sevde; Farid, Michael; Koh, Andrew Y.; Russ, William; Toprak, Erdal

A trimethoprim derivative impedes antibiotic resistance evolution

NATURE COMMUNICATIONS

IF15.7

2021-05-19

OAAI

Manna, Madhu Sudan; Tamer, Yusuf Talha; Gaszek, Ilona; Poulides, Nicole; Ahmed, Ayesha; Wang, Xiaoyu; Toprak, Furkan C. R.; Woodard, DaNae R.; Koh, Andrew Y.; Williams, Noelle S.; Borek, Dominika; Atilgan, Ali Rana; Hulleman, John D.; Atilgan, Canan; Tambar, Uttam; Toprak, Erdal

High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2019-04-15

OAAI

Tamer, Yusuf Talha; Gaszek, Ilona K.; Abdizadeh, Haleh; Batur, Tugce Altinusak; Reynolds, Kimberly A.; Atilgan, Ali Rana; Atilgan, Canan; Toprak, Erdal

On the Race to Starvation: How Do Bacteria Survive High Doses of Antibiotics?

MOLECULAR CELL

IF16.6

2017-12-01

OAAI

Tamer, Yusuf Talha; Toprak, Erdal

Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells (vol 7, 11641, 2016)

NATURE COMMUNICATIONS

IF15.7

2016-06-24

OAAI

Okumus, Burak; Landgraf, Dirk; Lai, Ghee Chuan; Bakshi, Somenath; Arias-Castro, Juan Carlos; Yildiz, Sadik; Huh, Dann; Fernandez-Lopez, Raul; Peterson, Celeste N.; Toprak, Erdal; El Karoui, Meriem; Paulsson, Johan

Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells

NATURE COMMUNICATIONS

IF15.7

2016-05-18

OAAI

Okumus, Burak; Landgraf, Dirk; Lai, Ghee Chuan; Bakhsi, Somenath; Carlos Arias-Castro, Juan; Yildiz, Sadik; Dann Huh; Fernandez-Lopez, Raul; Peterson, Celeste N.; Toprak, Erdal; El Karoui, Meriem; Paulsson, Johan

Computational Assessment of Trimethoprim Resistance in Dihydrofolate Reductase

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Abdizadeh, Haleh; Acar, Omer; Guclul, Tandac Furkan; Tamer, Yusuf Talha; Batur, Tugce Altinusak; Toprak, Erdal; Atilgan, Ali Rana; Atilgan, Canan

A Synthetic Knob for Modulating Antibiotic Resistance

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Ayhan, Dilay Hazal; Tamer, Yusuf Talha; Akbar, Mohammed; Greenberg, David E.; Toprak, Erdal

Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes

NATURE COMMUNICATIONS

IF15.7

2015-06-10

121

OAAI

Palmer, Adam C.; Toprak, Erdal; Baym, Michael; Kim, Seungsoo; Veres, Adrian; Bershtein, Shimon; Kishony, Roy

Strength of Selection Pressure Is an Important Parameter Contributing to the Complexity of Antibiotic Resistance Evolution

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2014-06-24

205

OAAI

Oz, Tugce; Guvenek, Aysegul; Yildiz, Sadik; Karaboga, Enes; Tamer, Yusuf Talha; Mumcuyan, Nirva; Ozan, Vedat Burak; Senturk, Gizem Hazal; Cokol, Murat; Yeh, Pamela; Toprak, Erdal

Fluidic and microfluidic tools for quantitative systems biology

CURRENT OPINION IN BIOTECHNOLOGY

IF7

2014-02-01

PREAI

Okumus, Burak; Yildiz, Sadik; Toprak, Erdal

Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition

NATURE PROTOCOLS

IF16

2013-02-21

129

PREAI