Brian Leyland‐Jones - Publications, H-index & Citations

Brian Leyland‐Jones

roche holding

65H指数

442论文数

3.2W被引数

收录论文 130

发表时间

Intra- and Interlaboratory Reproducibility of the Sensitivity to Endocrine Therapy Assay for Stage II/III Breast Cancer

CLINICAL CHEMISTRY

IF6.3

2021-08-10

OAAI

Bossuyt, Veerle; Lau, Rosanna; Young, Brandon; Howe, John Greg; Zhao, Fengmin; Leyland-Jones, Brian; Du, Lili; Foli, Tiffany; Hatzis, Christos; Symmans, W. Fraser

Dasatinib attenuates Src pathway signaling and combined with veliparib and carboplatin potently inhibits tumor growth in PTEN-null TNBC model

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Sun, Yuliang; Lin, Xiaoqian; Aske, Jennifer; Williams, Casey; Abramovitz, Mark; Leyland-Jones, Brian

Preclinical model of TNBC: Dasatinib attenuates Src pathway signaling and combined with veliparib and carboplatin potently inhibits tumor growth

CANCER RESEARCH

IF16.6

2020-02-15

PREAI

Sun, Yuliang; Lin, Xiaoqian; Aske, Jennifer; Williams, Casey; Abramovitz, Mark; Leyland-Jones, Brian

PI3Kα/δ inhibitor, copanlisib is highly effective in ER-positive breast cancer

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

De, Pradip; Aske, Jennifer C.; Williams, Casey; Dey, Nandini; Leyland-Jones, Brian

Dasatinib attenuates Src pathway signaling and combined with veliparib and carboplatin potently inhibits tumor growth in a preclinical model of TNBC

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Sun, Yuliang; Lin, Xiaoqian; Aske, Jennifer C.; Williams, Casey; Abramovitz, Mark; Leyland-Jones, Brian

Functional correlation between cancer stem cells and algorithmic effectiveness of targeted drugs of RAS and PI3K pathways in TNBC

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Aske, Jennifer C.; De, Pradip K.; Leyland-Jones, Brian; Dey, Nandini

Clinical benefit of molecularly-guided treatment strategies on progression free survival in patients with advanced gastrointestinal malignancies

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Buzard, Blake; Gonser, Tyler; Hinrichsen, Melissa; Amallraja, Anu; Williams, Kirstin; De, Pradip; Leyland-Jones, Brian; Elsey, Rachel; Meissner, Tobias; Williams, Casey

A comparative immune landscape within tumormicroenvironment: Pattern of distribution of immune cells in tumor versus tumor adjacent normal tissues

CANCER RESEARCH

IF16.6

2019-07-01

OAAI

Lin, Xiaoqian; Sulaiman, Read; Aske, Jennifer; Mayer, Paul; Rojas-Espaillat, Luis; Starks, David; De, Pradip; Leyland-Jones, Brian; Dey, Nandini

Mechanism-based evaluation of apoptosis in live tumor cells by triple co-fluorescence staining: Testing algorithmic effectiveness of targeted drugs

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Dey, Nandini; Aske, Jennifer C.; Williams, Casey; De, Pradip K.; Leyland-Jones, Brian

A laboratory friendly visualization method of triple-co-fluorescence staining to identify cytomorphological features of apoptosis simultaneously with biochemical events in live cells

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Leyland-Jones, Brian R.; Aske, Jennifer H.; De, Pradip; Dey, Nandini

Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study 癌症患者的分子谱可以实现个性化的联合治疗: i-predict研究

NATURE MEDICINE

IF50

2019-04-22

457

OAAI

Sicklick, Jason K.; Kato, Shumei; Okamura, Ryosuke; Schwaederle, Maria; Hahn, Michael E.; Williams, Casey B.; De, Pradip; Krie, Amy; Piccioni, David E.; Miller, Vincent A.; Ross, Jeffrey S.; Benson, Adam; Webster, Jennifer; Stephens, Philip J.; Lee, J. Jack; Fanta, Paul T.; Lippman, Scott M.; Leyland-Jones, Brian; Kurzrock, Razelle

PTEN expression at the nexus of oncogenic signals in TNBC: Testing combination of p110beta-isoform-specific inhibitor with five PARP inhibitors

CANCER RESEARCH

IF16.6

2019-02-15

PREAI

Dey, N.; Carlson, J. H.; De, P.; Leyland-Jones, B.

Genetic background determines the algorithm of effectiveness of targeted drugs of RAS and PI3K pathways in TNBC: Testing a combination of MEK 1/2 inhibitor with mTOR kinase inhibitor or AKT inhibitor

CANCER RESEARCH

IF16.6

2019-02-15

PREAI

Carlson, J. H.; De, P.; Dey, N.; Leyland-Jones, B.

Preclinical evaluation of the PI3Kα/δ inhibitor, copanlisib in HER2+breast cancer: A proof of concept study

CANCER RESEARCH

IF16.6

2019-02-15

PREAI

De, P.; Carlson, J. H.; Dey, N.; Leyland-Jones, B.

RET rearrangements are actionable alterations in breast cancer

NATURE COMMUNICATIONS

IF15.7

2018-11-16

OAAI

Paratala, Bhavna S.; Chung, Jon H.; Williams, Casey B.; Yilmazel, Bahar; Petrosky, Whitney; Williams, Kirstin; Schrock, Alexa B.; Gay, Laurie M.; Lee, Ellen; Dolfi, Sonia C.; Pham, Kien; Lin, Stephanie; Yao, Ming; Kulkarni, Atul; DiClemente, Frances; Liu, Chen; Rodriguez-Rodriguez, Lorna; Ganesan, Shridar; Ross, Jeffrey S.; Ali, Siraj M.; Leyland-Jones, Brian; Hirshfield, Kim M.

Triple Fluorescence staining to Evaluate Mechanism-based Apoptosis following Chemotherapeutic and Targeted Anti-cancer Drugs in Live Tumor Cells

SCIENTIFIC REPORTS

IF3.9

2018-09-04

OAAI

De, Pradip; Carlson, Jennifer H.; Leyland-Jones, Brian; Williams, Casey; Dey, Nandini

In vivo study of dasatinib in combination with veliparib plus carboplatin in triple-negative breast cancer xenograft models

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Sun, Yuliang; Lin, Xiaoqian; Carlson, Jennifer; De, Pradip; Dey, Nandini; Williams, Casey; Leyland-Jones, Brian

Tolerability and outcomes of trametinib and everolimus combinations in advanced solid tumors

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Patterson, Jason; Perry, Cory; Windscheffel, Joe; Elsey, Rachel; Williams, Kirstin; Dey, Nandini; De, Pradip; Leyland-Jones, Brian; Williams, Casey

Testing a combination of AKT inhibitor (AZD5363) with PARP inhibitor olaparib plus carboplatin in TNBC

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Carlson, Jennifer H.; O'Connor, Mark J.; Williams, Casey; De, Pradip; Dey, Nandini; Leyland-Jones, Brian

Validation of PD-L1 staining by IHC in solid tumors: A journey from xenograft model to ex vivo culture of clinical samples

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Lin, Xiaoqian; Carlson, Jennifer; Quast, Megan; Sun, Yuliang; Jepperson, Tyler; Williams, Casey; RojasEspaillat, Luis; Solomon, Benjamin; Starks, David; Krie, Amy; De, Pradip; Sulaiman, Raed; Dey, Nandini; Leyland-Jones, Brian

研究方向