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EYA2 tyrosine phosphatase inhibition reduces MYC and prevents medulloblastoma progression Wolin, Arthur R.; Vincent, Melanie Y.; Hotz, Taylor; Purdy, Stephen C.; Rosenbaum, Sheera R.; Hughes, Connor J.; Hsu, Jessica Y.; Oliphant, Michael U. J.; Armstrong, Brock; Wessells, Veronica; Varella-Garcia, Marileila; Galbraith, Matthew D.; Pierce, Angela; Wang, Dong; Venkataraman, Sujatha; Danis, Etienne; Veo, Bethany; Serkova, Natalie; Espinosa, Joaquin M.; Gustafson, Daniel L.; Vibhakar, Rajeev; Ford, Heide L. 分享 收藏
EGFR High Copy Number Together With High EGFR Protein Expression Predicts Improved Outcome for Cetuximab-based Therapy in Squamous Cell Lung Cancer: Analysis From SWOG S0819, a Phase III Trial of Chemotherapy With or Without Cetuximab in Advanced NSCLC Hirsch, Fred R.; Redman, Mary W.; Moon, James; Agustoni, Francesco; Herbst, Roy S.; Semrad, Thomas J.; Varella-Garcia, Marileila; Rivard, Chris J.; Kelly, Karen; Gandara, David R.; Mack, Philip C. 分享 收藏
Crizotinib in ROS1-rearranged advanced non-small-cell lung cancer (NSCLC): updated results, including overall survival, from PROFILE 1001 Shaw, A. T.; Riely, G. J.; Bang, Y-J; Kim, D-W; Camidge, D. R.; Solomon, B. J.; Varella-Garcia, M.; Iafrate, A. J.; Shapiro, G., I; Usari, T.; Wang, S. C.; Wilner, K. D.; Clark, J. W.; Ou, S-H, I 分享 收藏
Clinical and Molecular Characterization of Adult Glioblastomas in Southern Brazil Trevisan, Patricia; Graziadio, Carla; Koshiyama Rodrigues, Dayane Bohn; Machado Rosa, Rafael Fabiano; Soares, Fabiano Pasqualotto; Provenzi, Valentina Oliveira; Vieira de Oliveira, Ceres Andreia; Paskulin, Giorgio Adriano; Varella-Garcia, Marileila; Gazzola Zen, Paulo Ricardo 分享 收藏
Inter- and intra-tumor heterogeneity of SMAD4 loss in head and neck squamous cell carcinomas Hernandez, Ariel L.; Wang, Ying; Somerset, Hilary L.; Keysar, Stephen B.; Aisner, Dara L.; Marshall, Carrie; Bowles, Daniel W.; Karam, Sana D.; Raben, David; Jimeno, Antonio; Varella-Garcia, Marileila; Wang, Xiao-Jing 分享 收藏
Correlation of extent of ALK FISH positivity and crizotinib efficacy in three prospective studies of ALK-positive patients with non-small-cell lung cancer Soria, J. -C.; Ho, S. N.; Varella-Garcia, M.; Iafrate, A. J.; Solomon, B. J.; Shaw, A. T.; Blackhall, F.; Mok, T. S.; Wu, Y. -L.; Pestova, K.; Wilner, K. D.; Polli, A.; Paolini, J.; Lanzalone, S.; Green, S.; Camidge, D. R. 分享 收藏
Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors Reeser, Julie W.; Martin, Dorrelyn; Miya, Jharna; Kautto, Esko A.; Lyon, Ezra; Zhu, Eliot; Wing, Michele R.; Smith, Amy; Reeder, Matthew; Samorodnitsky, Eric; Parks, Hannah; Naik, Karan R.; Gozgit, Joseph; Nowacki, Nicholas; Davies, Kurtis D.; Varella-Garcia, Marileila; Yu, Lianbo; Freud, Aharon G.; Coleman, Joshua; Aisner, Dara L.; Roychowdhury, Sameek 分享 收藏
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EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases Vaishnavi, Aria; Schubert, Laura; Rix, Uwe; Marek, Lindsay A.; Le, Anh T.; Keysar, Stephen B.; Glogowska, Magdalena J.; Smith, Matthew A.; Kako, Severine; Sumi, Natalia J.; Davies, Kurtis D.; Ware, Kathryn E.; Varella-Garcia, Marileila; Haura, Eric B.; Jimeno, Antonio; Heasley, Lynn E.; Aisner, Dara L.; Doebele, Robert C. 分享 收藏
Do More With Less Tips and Techniques for Maximizing Small Biopsy and Cytology Specimens for Molecular and Ancillary Testing: The University of Colorado Experience Aisner, Dara L.; Rumery, Mathew D.; Merrick, Daniel T.; Kondo, Kimi L.; Nijmeh, Hala; Linderman, Derek J.; Doebele, Robert C.; Thomas, Natalie; Chesnut, Patrick C.; Varella-Garcia, Marileila; Franklin, Wilbur A.; Camidge, Ross 分享 收藏
Correlation of EGFR-expression with safety and efficacy outcomes in SQUIRE: a randomized, multicenter, open-label, phase III study of gemcitabine-cisplatin plus necitumumab versus gemcitabine-cisplatin alone in the first-line treatment of patients with stage IV squamous non-small-cell lung cancer Paz-Ares, L.; Socinski, M. A.; Shahidi, J.; Hozak, R. R.; Soldatenkova, V.; Kurek, R.; Varella-Garcia, M.; Thatcher, N.; Hirsch, F. R. 分享 收藏
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An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101 Doebele, Robert C.; Davis, Lara E.; Vaishnavi, Aria; Le, Anh T.; Estrada-Bernal, Adriana; Keysar, Stephen; Jimeno, Antonio; Varella-Garcia, Marileila; Aisner, Dara L.; Li, Yali; Stephens, J.; Morosini, Deborah; Tuch, Brian B.; Fernandes, Michele; Nanda, Nisha; Low, Jennifer A. 分享 收藏
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer Hrustanovic, Gorjan; Olivas, Victor; Pazarentzos, Evangelos; Tulpule, Asmin; Asthana, Saurabh; Blakely, Collin M.; Okimoto, Ross A.; Lin, Luping; Neel, Dana S.; Sabnis, Amit; Flanagan, Jennifer; Chan, Elton; Varella-Garcia, Marileila; Aisner, Dara L.; Vaishnavi, Aria; Ou, Sai-Hong I.; Collisson, Eric A.; Ichihara, Eiki; Mack, Philip C.; Lovly, Christine M.; Karachaliou, Niki; Rosell, Rafael; Riess, Jonathan W.; Doebele, Robert C.; Bivona, Trever G. 分享 收藏
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer NOTCH1基因拷贝数增加是结直肠癌中生存较差的预后指标，也是Notch1靶向抗体的预测性生物标志物 Arcaroli, John J.; Tai, W. M.; McWilliams, Ryan; Bagby, Stacey; Blatchford, Patrick J.; Varella-Garcia, Marileila; Purkey, Alicia; Quackenbush, Kevin S.; Song, Eun-Kee; Pitts, Todd M.; Gao, Dexiang; Lieu, Chris; McManus, Martine; Tan, Aik Choon; Zheng, Xianxian; Zhang, Qin; Ozeck, Mark; Olson, Peter; Jiang, Zhi-Qin; Kopetz, Scott; Jimeno, Antonio; Keysar, Stephen; Eckhardt, Gail; Messersmith, Wells A. 分享 收藏
KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas KIAA1549: BRAF基因融合和FGFR1热点突变是毛细胞型星形细胞瘤的预后因素 Becker, Aline Paixao; Scapulatempo-Neto, Cristovam; Carloni, Adriana C.; Paulino, Alessandra; Sheren, Jamie; Aisner, Dara L.; Musselwhite, Evelyn; Clara, Carlos; Machado, Helio R.; Oliveira, Ricardo S.; Neder, Luciano; Varella-Garcia, Marileila; Reis, Rui M. 分享 收藏
Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy Despierre, Evelyn; Vergote, Ignace; Anderson, Ryan; Coens, Corneel; Katsaros, Dionyssios; Hirsch, Fred R.; Boeckx, Bram; Varella-Garcia, Marileila; Ferrero, Annamaria; Ray-Coquard, Isabelle; Berns, Els M. J. J.; Casado, Antonio; Lambrechts, Diether; Jimeno, Antonio 分享 收藏
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer Morton, J. J.; Bird, G.; Keysar, S. B.; Astling, D. P.; Lyons, T. R.; Anderson, R. T.; Glogowska, M. J.; Estes, P.; Eagles, J. R.; Le, P. N.; Gan, G.; McGettigan, B.; Fernandez, P.; Padilla-Just, N.; Varella-Garcia, M.; Song, J. I.; Bowles, D. W.; Schedin, P.; Tan, A-C; Roop, D. R.; Wang, X-J; Refaeli, Y.; Jimeno, A. 分享 收藏
Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tract Alese, Olatunji B.; El-Rayes, Bassel F.; Sica, Gabriel; Zhang, Guojing; Alexis, Dianne; La Rosa, Francisco G.; Varella-Garcia, Marileila; Chen, Zhengjia; Rossi, Michael R.; Adsay, Nazim V.; Khuri, Fadlo R.; Owonikoko, Taofeek K. 分享 收藏
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