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收藏Discovery of an asymmetric IgG-like bispecific ADC targeting EGFR/HER3
Chen, Liandi; Peng, Shaogang; Wang, Chao; Miao, Xiaoniu; Yan, Yao; Xing, Jun; Huang, Weifeng; Tsun, Andy; Xu, Yingda; Liu, Xiaolin; Luo, Yi 分享 收藏 Discovery and development of an asymmetric IgG-like bispecific antibody targeting EGFR and c-MET, engineered through H-H and H-L chain charge-based heterodimerizationWang, Ping; Huang, Weifeng; Zhao, Zhenting; Miao, Xiaoniu; Peng, Shaogang; Wang, Chao; Yan, Yao; Dong, Tiantian; Tsun, Andy; Xu, Yingda; Liu, Xiaolin; Yi, Luo 分享 收藏 A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy阻止SARS-CoV-2感染的新型双互补位混合antibody-ACE2融合: 对治疗的影响Miao, Xiaoniu; Luo, Yi; Huang, Xi; Lee, Suki M. Y.; Yuan, Zhijun; Tang, Yongzhou; Chen, Liandi; Wang, Chao; Wu, Fan; Xu, Yifeng; Jiang, Wenchao; Gao, Wei; Song, Xuedong; Yan, Yao; Pang, Tuling; Chen, Cheng; Zou, Yuefeng; Fu, Weihui; Wan, Liping; Gilbert-Jaramillo, Javier; Knight, Michael; Tan, Tiong Kit; Rijal, Pramila; Townsend, Alain; Sun, Joanne; Liu, Xiaolin; James, William; Tsun, Andy; Xu, Yingda 分享 收藏 Affinity Maturation Enhances Antibody Specificity but Compromises Conformational StabilityShehata, Laila; Maurer, Daniel P.; Wec, Anna Z.; Lilov, Asparouh; Champney, Elizabeth; Sun, Tingwan; Archambault, Kimberly; Burnina, Irina; Lynaugh, Heather; Zhi, Xiaoyong; Xu, Yingda; Walker, Laura M. 分享 收藏 Structure, heterogeneity and developability assessment of therapeutic antibodiesXu, Yingda; Wang, Dongdong; Mason, Bruce; Rossomando, Tony; Li, Ning; Liu, Dingjiang; Cheung, Jason K.; Xu, Wei; Raghava, Smita; Katiyar, Amit; Nowak, Christine; Xiang, Tao; Dong, Diane D.; Sun, Joanne; Beck, Alain; Liu, Hongcheng 分享 收藏 分享 收藏 Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment缺血性卒中早期血压及卒中亚型对卒中后认知功能障碍的影响He, Mingli; Wang, Jin'e; Liu, Na; Xiao, Xiao; Geng, Shan; Meng, Pin; Ji, Niu; Sun, Yong'an; Xu, Bingchao; Xu, Yingda; Zhou, Xinyu; Zhang, Guanghui; He, Xiaobing; Cai, Zenglin; Li, Zaipo; Wang, Bei; Xu, Bei; Hui, Rutai; Wang, Yibo 分享 收藏 Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteinsYang, Nicole J.; Kauke, Monique J.; Sun, Fangdi; Yang, Lucy F.; Maass, Katie F.; Traxlmayr, Michael W.; Yu, Yao; Xu, Yingda; Langer, Robert S.; Anderson, Daniel G.; Wittrup, K. Dane 分享 收藏 Mid-Term Blood Pressure Variability Is Associated With Clinical Outcome After Ischemic Stroke缺血性卒中后中期血压变异性与临床结局相关Wang, Yibo; Wang, Jin'e; Meng, Pin; Liu, Na; Ji, Niu; Zhang, Guanghui; Xu, Bingchao; Zhou, Xinyu; Sun, Yong'an; Xu, Yingda; Hui, Rutai; He, Mingli 分享 收藏 Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodiesYang, Rong; Jain, Tushar; Lynaugh, Heather; Nobrega, R. Paul; Lu, Xiaojun; Boland, Todd; Burnina, Irina; Sun, Tingwan; Caffry, Isabelle; Brown, Michael; Zhi, Xiaoyong; Lilov, Asparouh; Xu, Yingda 分享 收藏 Biophysical properties of the clinical-stage antibody landscape临床阶段抗体景观的生物物理特性Jain, Tushar; Sun, Tingwan; Durand, Stephanie; Hall, Amy; Houston, Nga Rewa; Nett, Juergen H.; Sharkey, Beth; Bobrowicz, Beata; Caffry, Isabelle; Yu, Yao; Cao, Yuan; Lynaugh, Heather; Brown, Michael; Baruah, Hemanta; Gray, Laura T.; Krauland, Eric M.; Xu, Yingda; Vasquez, Maximiliano; Wittrup, K. Dane 分享 收藏 Broad epitope coverage of a human in vitro antibody librarySivasubramanian, Arvind; Estep, Patricia; Lynaugh, Heather; Yu, Yao; Miles, Adam; Eckman, Josh; Schutz, Kevin; Piffath, Crystal; Boland, Nadthakarn; Niles, Rebecca Hurley; Durand, Stephanie; Boland, Todd; Vasquez, Maximiliano; Xu, Yingda; Abdiche, Yasmina 分享 收藏 分享 收藏 High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in miceKelly, Ryan L.; Sun, Tingwan; Jain, Tushar; Caffry, Isabelle; Yu, Yao; Cao, Yuan; Lynaugh, Heather; Brown, Michael; Vasquez, Maximiliano; Wittrup, K. Dane; Xu, Yingda 分享 收藏 An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodiesEstep, Patricia; Caffry, Isabelle; Yu, Yao; Sun, Tingwan; Cao, Yuan; Lynaugh, Heather; Jain, Tushar; Vasquez, Maximiliano; Tessier, Peter M.; Xu, Yingda 分享 收藏 分享 收藏 分享 收藏 High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopyLiu, Yuqi; Caffry, Isabelle; Wu, Jiemin; Geng, Steven B.; Jain, Tushar; Sun, Tingwan; Reid, Felicia; Cao, Yuan; Estep, Patricia; Yu, Yao; Vasquez, Maximiliano; Tessier, Peter M.; Xu, Yingda 分享 收藏 Serum and Glucocorticoid-induced Kinase (SGK) 1 and the Epithelial Sodium Channel Are Regulated by Multiple with No Lysine (WNK) Family MembersHeise, Charles J.; Xu, Bing-e; Deaton, Staci L.; Cha, Seung-Kuy; Cheng, Chih-Jen; Earnest, Svetlana; Sengupta, Samarpita; Juang, Yu-Chi; Stippec, Steve; Xu, Yingda; Zhao, Yingming; Huang, Chou-Long; Cobb, Melanie H. 分享 收藏 
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