Dietmar Gradl - Publications, H-index & Citations

Dietmar Gradl

Charles University Prague

24H指数

95论文数

2.9K被引数

收录论文 21

发表时间

Parenchymal cues define Vegfa-driven venous angiogenesis by activating a sprouting competent venous endothelial subtype

NATURE COMMUNICATIONS

IF15.7

2024-04-10

OAAI

Preau, Laetitia; Lischke, Anna; Merkel, Melanie; Oegel, Neslihan; Weissenbruch, Maria; Michael, Andria; Park, Hongryeol; Gradl, Dietmar; Kupatt, Christian; le Noble, Ferdinand

Lef1 regulates caveolin expression and caveolin dependent endocytosis, a process necessary for Wnt5a/Ror2 signaling during Xenopus gastrulation

SCIENTIFIC REPORTS

IF3.9

2019-10-30

OAAI

Puzik, Katharina; Tonnier, Veronika; Opper, Isabell; Eckert, Antonia; Zhou, Lu; Kratzer, Marie-Claire; le Noble, Ferdinand; Nienhaus, Gerd Ulrich; Gradl, Dietmar

Secreted Frizzled-related Protein 2 (sFRP2) Redirects Non-canonical Wnt Signaling from Fz7 to Ror2 during Vertebrate Gastrulation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-06-01

OAAI

Brinkmann, Eva-Maria; Mattes, Benjamin; Kumar, Rahul; Hagemann, Anja I. H.; Gradl, Dietmar; Scholpp, Steffen; Steinbeisser, Herbert; Kaufmann, Lilian T.; Oezbek, Suat

A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway

CELL DISCOVERY

IF12.5

2016-01-05

OAAI

Mittag, Sonnhild; Valenta, Tomas; Weiske, Joerg; Bloch, Laura; Klingel, Susanne; Gradl, Dietmar; Wetzel, Franziska; Chen, Yuan; Petersen, Iver; Basler, Konrad; Huber, Otmar

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane

SCIENCE SIGNALING

IF6.6

2015-09-08

PREAI

Loregger, Anke; Grandl, Martina; Mejias-Luque, Raquel; Allgaeuer, Michael; Degenhart, Kathrin; Haselmann, Verena; Oikonomou, Christina; Hatzis, Pantelis; Janssen, Klaus-Peter; Nitsche, Ulrich; Gradl, Dietmar; van den Broek, Olaf; Destree, Olivier; Ulm, Kurt; Neumaier, Michael; Kalali, Behnam; Jung, Andreas; Varela, Ignacio; Schmid, Roland M.; Rad, Roland; Busch, Dirk H.; Gerhard, Markus

CD44 functions in Wnt signaling by regulating LRP6 localization and activation

CELL DEATH AND DIFFERENTIATION

IF15.4

2014-10-10

133

OAAI

Schmitt, M.; Metzger, M.; Gradl, D.; Davidson, G.; Orian-Rousseau, V.

Monensin Inhibits Canonical Wnt Signaling in Human Colorectal Cancer Cells and Suppresses Tumor Growth in Multiple Intestinal Neoplasia Mice

MOLECULAR CANCER THERAPEUTICS

IF5.5

2014-04-06

OAAI

Tumova, Lucie; Pombinho, Antonio R.; Vojtechova, Martina; Stancikova, Jitka; Gradl, Dietmar; Krausova, Michaela; Sloncova, Eva; Horazna, Monika; Kriz, Vitezslav; Machonova, Olga; Jindrich, Jindrich; Zdrahal, Zbynek; Bartunek, Petr; Korinek, Vladimir

STED-RICS - A Versatile Method for Studying Biomolecular Dynamics in Live Cells

BIOPHYSICAL JOURNAL

IF3.1

2014-01-01

OAAI

Hedde, Per Niklas; Doerlich, Rene M.; Blomley, Rosmarie; Gradl, Dietmar; Oppong, Emmanuel; Cato, Andrew C. B. Cato; Nienhaus, G. Ulrich

Stimulated emission depletion-based raster image correlation spectroscopy reveals biomolecular dynamics in live cells

NATURE COMMUNICATIONS

IF15.7

2013-06-27

OAAI

Hedde, Per Niklas; Doerlich, Rene M.; Blomley, Rosmarie; Gradl, Dietmar; Oppong, Emmanuel; Cato, Andrew C. B.; Nienhaus, G. Ulrich

Synthesis of novel inhibitors blocking Wnt signaling downstream of β-Catenin

FEBS LETTERS

IF3

2013-01-25

PREAI

Halbedl, Sonja; Kratzer, Marie-Claire; Rahm, Karolin; Crosta, Nicoletta; Masters, Kye-Simeon; Zippert, Jessica; Braese, Stefan; Gradl, Dietmar

A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice

CANCER RESEARCH

IF16.6

2012-05-31

313

OAAI

Waaler, Jo; Machon, Ondrej; Tumova, Lucie; Dinh, Huyen; Korinek, Vladimir; Wilson, Steven Ray; Paulsen, Jan Erik; Pedersen, Nina Marie; Eide, Tor J.; Machonova, Olga; Gradl, Dietmar; Voronkov, Andrey; von Kries, Jens Peter; Krauss, Stefan

Live imaging of active fluorophore labelled Wnt proteins

FEBS LETTERS

IF3

2012-04-26

PREAI

Holzer, Tatjana; Liffers, Katrin; Rahm, Karolin; Trageser, Benjamin; Oezbek, Suat; Gradl, Dietmar

Diffusion- and convection-based activation of Wnt/β-catenin signaling in a gradient generating microfluidic chip

LAB ON A CHIP

IF5.4

2012-01-01

PREAI

Kim, Chorong; Kreppenhofer, Kristina; Kashef, Jubin; Gradl, Dietmar; Herrmann, Dirk; Schneider, Marc; Ahrens, Ralf; Guber, Andreas; Wedlich, Doris

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling

CELLULAR SIGNALLING

IF3.7

2011-05-01

100

PREAI

Doubravska, Lenka; Krausova, Michaela; Gradl, Dietmar; Vojtechova, Martina; Tumova, Lucie; Lukas, Jan; Valenta, Tomas; Pospichalova, Vendula; Fafilek, Bohumil; Plachy, Jiri; Sebesta, Ondrej; Korinek, Vladimir

Novel Synthetic Antagonists of Canonical Wnt Signaling Inhibit Colorectal Cancer Cell Growth

CANCER RESEARCH

IF16.6

2011-01-02

166

OAAI

Waaler, Jo; Machon, Ondrej; von Kries, Jens Peter; Wilson, Steven Ray; Lundenes, Elsa; Wedlich, Doris; Gradl, Dietmar; Paulsen, Jan Erik; Machonova, Olga; Dembinski, Jennifer L.; Dinh, Huyen; Krauss, Stefan

Near-Field Optical Study of Protein Transport Kinetics at a Single Nuclear Pore

NANO LETTERS

IF9.1

2009-07-10

PREAI

Herrmann, Michael; Neuberth, Nicole; Wissler, Joerg; Perez, Jose; Gradl, Dietmar; Naber, Andreas

β-arrestin is a necessary component of Wnt/β-catenin signaling in vitro and in vivo

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2007-04-17

147

OAAI