未登录SUMOylation inhibitor TAK-981 (subasumstat) synergizes with 5-azacytidine in preclinical models of acute myeloid leukemia
Gabellier, Ludovic; De Toledo, Marion; Chakraborty, Mehuli; Akl, Dana; Hallal, Rawan; Aqrouq, Mays; Buonocore, Giovanni; Recasens-Zorzo, Clara; Cartron, Guillaume; Delort, Abigail; Piechaczyk, Marc; Tempe, Denis; Bossis, Guillaume
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收藏DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias
Boulanger, Mathias; Aqrouq, Mays; Tempe, Denis; Kifagi, Chamseddine; Ristic, Marko; Akl, Dana; Hallal, Rawan; Carusi, Aude; Gabellier, Ludovic; de Toledo, Marion; Sigurdsson, Jon-Otti; Kaoma, Tony; Andrieu-Soler, Charlotte; Forne, Thierry; Soler, Eric; Hicheri, Yosr; Gueret, Elise; Vallar, Laurent; Olsen, Jesper, V; Cartron, Guillaume; Piechaczyk, Marc; Bossis, Guillaume
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收藏Down-regulation of c-Fos/c-Jun AP-1 Dimer activity by sumoylation
Bossis, G; Malnou, CE; Farras, R; Andermarcher, E; Hipskind, R; Rodriguez, M; Schmidt, D; Muller, S; Jariel-Encontre, I; Piechaczyk, M
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收藏New roles for AP-1/JUNB in cell cycle control and tumorigenic cell invasion via regulation of cyclin E1 and TGF-β2
Perez-Benavente, Beatriz; Fathinajafabadi, Alihamze; de la Fuente, Lorena; Gandia, Carolina; Martinez-Ferriz, Arantxa; Pardo-Sanchez, Jose Miguel; Milian, Lara; Conesa, Ana; Romero, Octavio A.; Carretero, Julian; Matthiesen, Rune; Jariel-Encontre, Isabelle; Piechaczyk, Marc; Farras, Rosa
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收藏The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
Paolillo, Rosa; Boulanger, Mathias; Gatel, Pierre; Gabellier, Ludovic; De Toledo, Marion; Tempe, Denis; Hallal, Rawan; Akl, Dana; Moreaux, Jerome; Baik, Hayeon; Gueret, Elise; Recher, Christian; Sarry, Jean-Emmanuel; Cartron, Guillaume; Piechaczyk, Marc; Bossis, Guillaume
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收藏Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers
Bejjani, Fabienne; Tolza, Claire; Boulanger, Mathias; Downes, Damien; Romero, Raphael; Maqbool, Muhammad Ahmad; El Aabidine, Amal Zine; Andrau, Jean-Christophe; Lebre, Sophie; Brehelin, Laurent; Parrinello, Hughes; Rohmer, Marine; Kaoma, Tony; Vallar, Laurent; Hughes, Jim R.; Zibara, Kazem; Lecellier, Charles-Henri; Piechaczyk, Marc; Jariel-Encontre, Isabelle
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收藏Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia
Hosseini, Mohsen; Rezvani, Hamid Reza; Aroua, Nesrine; Bosc, Claudie; Farge, Thomas; Saland, Estelle; Guyonnet-Duperat, Veronique; Zaghdoudi, Sonia; Jarrou, Latifa; Larrue, Clement; Sabatier, Marie; Mouchel, Pierre Luc; Gotanegre, Mathilde; Piechaczyk, Marc; Bossis, Guillaume; Recher, Christian; Sarry, Jean-Emmanuel
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收藏AP-1 Signaling by Fra-1 Directly Regulates HMGA1 Oncogene Transcription in Triple-Negative Breast Cancers
Tolza, Claire; Bejjani, Fabienne; Evanno, Emilie; Mahfoud, Samantha; Moquet-Torcy, Gabriel; Gostan, Thierry; Maqbool, Muhammad Ahmad; Kirsh, Olivier; Piechaczyk, Marc; Jariel-Encontre, Isabelle
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收藏Targeting the SUMO Pathway Primes An-trans Retinoic Acid-Induced Differentiation of Nonpromyelocytic Acute Myeloid Leukemias
Baik, Hayeon; Boulanger, Mathias; Hosseini, Mohsen; Kowalczyk, Julie; Zaghdoudi, Sonia; Salem, Tamara; Sarry, Jean-Emmanuel; Hicheri, Yosr; Cartron, Guillaume; Piechaczyk, Marc; Bossis, Guillaume
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