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收藏High-Throughput Screening for Extracellular Inhibitors of the FLT3 Receptor Tyrosine Kinase Reveals Chemically Diverse and Druggable Negative Allosteric ModulatorsFLT3受体酪氨酸激酶细胞外抑制剂的高通量筛选揭示了化学多样性和可服用的负变构调节剂
Hany, Romain; Leyris, Jean-Philippe; Bret, Guillaume; Mallie, Sylvie; Sar, Chamroeun; Thouaye, Maxime; Hamze, Abdallah; Provot, Olivier; Sokoloff, Pierre; Valmier, Jean; Villa, Pascal; Rognan, Didier
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收藏Pharmacology profile of F17464, a dopamine D3 receptor preferential antagonist
Cosi, Cristina; Martel, Jean-Claude; Auclair, Agnes L.; Collo, Ginetta; Cavalleri, Laura; Heusler, Peter; Leriche, Ludovic; Gaudoux, Florence; Sokoloff, Pierre; Moser, Paul C.; Gatti-McArthur, Silvia
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收藏F17464 a new antipsychotic with preferential D3 antagonist, 5-HT1A partial agonist properties. Neurochemical studies
Cosi, C.; N'Guyen, V.; Consul-Denjean, N.; Auclair, A.; Heusler, P.; Martel, J. C.; Leriche, L.; Sokoloff, P.; Gatti-McArthur, S.
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收藏Binding of the D3-preferring antipsychotic candidate F17464 to dopamine D3 and D2 receptors: a PET study in healthy subjects with [11C]-(+)-PHNOD3-preferring抗精神病药候选物F17464与多巴胺D3和D2受体的结合: [11C]-( )-PHNO在健康受试者中的PET研究
Slifstein, Mark; Abi-Darghami, Anissa; Girgis, Ragy R.; Suckow, Raymond F.; Coopers, Thomas B.; Divgi, Chaitanya R.; Sokoloff, Pierre; Leriche, Ludovic; Carberry, Patrick; Oya, Shunichi; Joseph, Simon K.; Guiraud, Marlene; Montagne, Agnes; Brunner, Valerie; Gaudoux, Florence; Tonner, Francoise
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收藏Randomized, double-blind, placebo-controlled study of F17464, a preferential D3 antagonist, in the treatment of acute exacerbation of schizophrenia
Bitter, Istvan; Lieberman, Jeffrey A.; Gaudoux, Florence; Sokoloff, Pierre; Groc, Melanie; Chavda, Rajeev; Delsol, Cecile; Barthe, Laurence; Brunner, Valerie; Fabre, Carine; Fagard, Marine; Montagne, Agnes; Tonner, Francoise
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收藏Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice
Rivat, Cyril; Sar, Chamroeun; Mechaly, Ilana; Leyris, Jean-Philippe; Diouloufet, Lucie; Sonrier, Corinne; Philipson, Yann; Lucas, Olivier; Mallie, Sylvie; Jouvenel, Antoine; Tassou, Adrien; Haton, Henri; Venteo, Stephanie; Pin, Jean-Philippe; Trinquet, Eric; Charrier-Savournin, Fabienne; Mezghrani, Alexandre; Joly, Willy; Mion, Julie; Schmitt, Martine; Pattyn, Alexandre; Marmigere, Frederic; Sokoloff, Pierre; Carroll, Patrick; Rognan, Didier; Valmier, Jean
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收藏Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies焦谷氨酸二甲氨基乙醇 (DMAE p-glu) 对东莨菪碱引起的记忆障碍的影响: 来自临床前研究和临床研究的证据
Blin, Olivier; Audebert, Christine; Pitel, Severine; Kaladjian, Arthur; Casse-Perrot, Catherine; Zaim, Mohammed; Micallef, Joelle; Tisne-Versailles, Jacky; Sokoloff, Pierre; Chopin, Philippe; Marien, Marc
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