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Endogenously produced itaconate negatively regulates innate-driven cytokine production and drives global ubiquitination in human macrophages Bourner, Luke A.; Chung, Linda A.; Long, Haiyan; McGettrick, Anne F.; Xiao, Junpeng; Roth, Kenneth; Bailey, Jade D.; Strickland, Marie; Tan, Bo; Cunningham, Jason; Lutzke, Barry; McGee, James; Otero, Francella J.; Gemperline, David C.; Zhang, Lin; Wang, Ying C.; Chalmers, Michael J.; Yang, Chiao-Wen; Gutierrez, Jesus A.; O'Neill, Luke A. J.; Dorsey, Frank C. 分享 收藏
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Artesunate promoted anti-tumor immunity and overcame EGFR-TKI resistance in non-small-cell lung cancer by enhancing oncogenic TAZ degradation Cao, Dai; Chen, Die; Xia, Jiang-Nan; Wang, Wen-Yan; Zhu, Guo-Yuan; Chen, Li-Wen; Zhang, Chuantao; Tan, Bo; Li, Hui; Li, Ying-Wei 分享 收藏
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Prospective Phase I Trial of Concurrent Full Dose Gemcitabine/Nab-paclitaxel and Ablative Radiation Therapy for Borderline and Locally Advanced Pancreatic Cancer Kim, H.; Olsen, J. R.; Wang-Gillam, A.; Green, O. L.; Fields, R. C.; Hammill, C.; Strasberg, S.; Doyle, M. B.; Hawkins, W.; Suresh, R.; Tan, B.; Pedersen, K.; Henke, L. E.; DeWees, T. A.; Chapman, W.; Parikh, P. J.; Roach, M. C., Jr. 分享 收藏
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Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration Zhao, Genshi; Green, Colin F.; Hui, Yu-Hua; Prieto, Lourdes; Shepard, Robert; Dong, Sucai; Wang, Tao; Tan, Bo; Gong, Xueqian; Kays, Lisa; Johnson, Robert L.; Wu, Wenjuan; Bhattachar, Shobha; Del Prado, Miriam; Gillig, James R.; Fernandez, Maria-Carmen; Roth, Ken D.; Buchanan, Sean; Kuo, Ming-Shang; Geeganage, Sandaruwan; Burkholder, Timothy P. 分享 收藏
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Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells 抑制NAD生物合成必需的烟酰胺磷酸核糖基转移酶 (NAMPT) 会导致癌细胞中碳水化合物代谢的改变 Tan, Bo; Dong, Sucai; Shepard, Robert L.; Kays, Lisa; Roth, Kenneth D.; Geeganage, Sandaruwan; Kuo, Ming-Shang; Zhao, Genshi 分享 收藏
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Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells METABOLIC BASIS AND POTENTIAL CLINICAL IMPLICATIONS Tan, Bo; Young, Debra A.; Lu, Zhao-Hai; Wang, Tao; Meier, Timothy I.; Shepard, Robert L.; Roth, Kenneth; Zhai, Yan; Huss, Karen; Kuo, Ming-Shang; Gillig, James; Parthasarathy, Saravanan; Burkholder, Timothy P.; Smith, Michele C.; Geeganage, Sandaruwan; Zhao, Genshi 分享 收藏
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