Leonard H. Augenlicht - Publications, H-index & Citations

Leonard H. Augenlicht

Bronx

61H指数

363论文数

1.3W被引数

收录论文 89

发表时间

High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer 高通量筛选鉴定出NT-1，其与MRTX1133协同作用对抗获得性耐药的KRASG12D结直肠癌

npj Precision Oncology

IF8

2026-04-08

OAAI

Natalie Thielen; Ning Wei; Emiko Nagai; Michele Houston; Leonard H. Augenlicht; Alice E. Shin; Joel T. Gabre; Anil K. Rustgi; Grace Ha; Lindsay M. LaFave; Edward Chu; Seiya Kitamura; Chaoyuan Kuang

Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation

NATURE GENETICS

IF31.8

2024-06-20

OAAI

Verhagen, Mathijs P.; Joosten, Rosalie; Schmitt, Mark; Vaelimaeki, Niko; Sacchetti, Andrea; Rajamaeki, Kristiina; Choi, Jiahn; Procopio, Paola; Silva, Sara; van der Steen, Berdine; van den Bosch, Thierry P. P.; Seinstra, Danielle; de Vries, Annemarie C.; Doukas, Michail; Augenlicht, Leonard H.; Aaltonen, Lauri A.; Fodde, Riccardo

Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges

EXPERIMENTAL AND MOLECULAR MEDICINE

IF12.9

2024-03-01

OAAI

Choi, Jiahn; Augenlicht, Leonard H.

Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-01-01

OAAI

Bedard, Gabriel T.; Gilaj, Nord; Peregrina, Karina; Brew, Isabella; Tosti, Elena; Shaffer, Karl; Tyler, Peter C.; Edelmann, Winfried; Augenlicht, Leonard H.; Schramm, Vern L.

EOGT enables residual Notch signaling in mouse intestinal cells lacking POFUT1

SCIENTIFIC REPORTS

IF3.9

2023-10-14

OAAI

Nauman, Mohd; Varshney, Shweta; Choi, Jiahn; Augenlicht, Leonard H.; Stanley, Pamela

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

143

OAAI

Hulit, J; Wang, CG; Li, ZP; Albanese, C; Rao, M; Di Vizio, D; Shah, S; Byers, SW; Mahmood, R; Augenlicht, LH; Russell, R; Pestell, RG

Kaiso-deficient mice show resistance to intestinal cancer

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

170

OAAI

Prokhortchouk, A; Sansom, O; Selfridge, J; Caballero, IM; Salozhin, S; Aithozhina, D; Cerchietti, L; Meng, FG; Augenlicht, LH; Mariadason, JM; Hendrich, B; Melnick, A; Prokhortchouk, E; Clarke, A; Bird, A

Intestinal stem cell aging at single-cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics

AGING CELL

IF7.1

2023-03-02

OAAI

Choi, Jiahn; Houston, Michele; Wang, Ruixuan; Ye, Kenny; Li, Wenge; Zhang, Xusheng; Huffman, Derek M.; Augenlicht, Leonard H.

Bacterial hydrogen sulfide drives cryptic redox chemistry in gut microbial communities

NATURE METABOLISM

IF20.8

2022-10-20

OAAI

Wolfson, Sarah J.; Hitchings, Reese; Peregrina, Karina; Cohen, Ziv; Khan, Saad; Yilmaz, Tugba; Malena, Marcel; Goluch, Edgar D.; Augenlicht, Leonard; Kelly, Libusha

Transition state analogue of MTAP extends lifespan of APCMin/+ mice

SCIENTIFIC REPORTS

IF3.9

2021-04-23

OAAI

Firestone, Ross S.; Feng, Mu; Basu, Indranil; Peregrina, Karina; Augenlicht, Leonard H.; Schramm, Vern L.

Effects of diet choice on stem cell function necessitate clarity in selection and reporting (vol 27, pg 11, 2020)

CELL STEM CELL

IF20.4

2021-04-01

OAAI

Li, Wenge; Houston, Michele; Peregrina, Karina; Ye, Kenny; Augenlicht, Leonard H.

Effects of Diet Choice on Stem Cell Function Necessitate Clarity in Selection and Reporting

CELL STEM CELL

IF20.4

2020-07-01

OAAI

Li, Wenge; Houston, Michele; Peregrina, Karina; Ye, Kenny; Augenlicht, Leonard H.

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2019-11-27

OAAI

Tang, Alan T.; Sullivan, Katie R.; Hong, Courtney C.; Goddard, Lauren M.; Mahadevan, Aparna; Ren, Aileen; Pardo, Heidy; Peiper, Amy; Griffin, Erin; Tanes, Ceylan; Mattei, Lisa M.; Yang, Jisheng; Li, Li; Mericko-Ishizuka, Patricia; Shen, Le; Hobson, Nicholas; Girard, Romuald; Lightle, Rhonda; Moore, Thomas; Shenkar, Robert; Polster, Sean P.; Roedel, Claudia J.; Li, Ning; Zhu, Qin; Whitehead, Kevin J.; Zheng, Xiangjian; Akers, Amy; Morrison, Leslie; Kim, Helen; Bittinger, Kyle; Lengner, Christopher J.; Schwaninger, Markus; Velcich, Anna; Augenlicht, Leonard; Abdelilah-Seyfried, Salim; Min, Wang; Marchuk, Douglas A.; Awad, Issam A.; Kahn, Mark L.

The nutritional environment determines which and how intestinal stem cells contribute to homeostasis and tumorigenesis

CARCINOGENESIS

IF2.9

2019-06-05

OAAI

Li, Wenge; Zimmerman, Samuel E.; Peregrina, Karina; Houston, Michele; Mayoral, Joshua; Zhang, Jinghang; Maqbool, Shahina; Zhang, Zhengdong; Cai, Ying; Ye, Kenny; Augenlicht, Leonard H.

Modelling western dietary habits in the mouse: easier said than done 在鼠标中建模西方饮食习惯: 说起来容易做起来难

HEPATOBILIARY SURGERY AND NUTRITION

IF7.8

2017-04-01

OAAI

Fodde, Riccardo; Schmitt, Mark; Schewe, Matthias; Augenlicht, Leonard H.

Environmental Impact on Intestinal Stem Cell Functions in Mucosal Homeostasis and Tumorigenesis 环境对粘膜稳态和肿瘤发生中肠道干细胞功能的影响

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2017-01-11

OAAI

Augenlicht, Leonard H.

Intestinal stem cells are sentinel cells for nutritional exposure

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Augenlicht, Leonard H.; Li, Wenge; Peregrina, Karina; Houston, Michele

NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells

CANCER RESEARCH

IF16.6

2016-05-31

OAAI

Srinivasan, Tara; Walters, Jewell; Bu, Pengcheng; Than, Elaine Bich; Tung, Kuei-Ling; Chen, Kai-Yuan; Panarelli, Nicole; Milsom, Jeff; Augenlicht, Leonard; Lipkin, Steven M.; Shen, Xiling

Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells

SCIENTIFIC REPORTS

IF3.9

2016-05-16

OAAI

Srinivasan, Tara; Than, Elaine Bich; Bu, Pengcheng; Tung, Kuei-Ling; Chen, Kai-Yuan; Augenlicht, Leonard; Lipkin, Steven M.; Shen, Xiling

Calcium and 1,25-dihydroxyvitamin D3 modulate genes of immune and inflammatory pathways in the human colon: a human crossover trial

AMERICAN JOURNAL OF CLINICAL NUTRITION

IF6.9

2016-05-01

OAAI

Protiva, Petr; Pendyala, Swaroop; Nelson, Celeste; Augenlicht, Leonard H.; Lipkin, Martin; Holt, Peter R.

研究方向