未登录 Mechanisms of Resistance to HER2-Targeted Therapies in HER2-positive Breast Cancer Veeraraghavan, Jamunarani; Liao, Fu-Tien; Qin, Lanfang; Gordon, Tia; Raghavan, Alekya; Sabotta, Caroline; Kaplan, Rachel; Gutierrez, Carolina; Osborne, C. Kent; Rimawi, Mothaffar F.; Schiff, Rachel 分享 收藏
High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer Fu, Xiaoyong; Pereira, Resel; Liu, Chia -Chia; De Angelis, Carmine; Shea, Martin J.; Nanda, Sarmistha; Qin, Lanfang; Mitchell, Tamika; Cataldo, Maria L.; Veeraraghavan, Jamunarani; Sethunath, Vidyalakshmi; Giuliano, Mario; Gutierrez, Carolina; Gyorffy, Balazs; Trivedi, Meghana, V; Cohen, Ofir; Wagle, Nikhil; Nardone, Agostina; Jeselsohn, Rinath; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel 分享 收藏
Proteogenomic Markers of Chemotherapy Resistance and Response in Triple-Negative Breast Cancer Anurag, Meenakshi; Jaehnig, Eric J.; Krug, Karsten; Lei, Jonathan T.; Bergstrom, Erik J.; Kim, Beom-Jun; Vashist, Tanmayi D.; Huynh, Anh Minh Tran; Dou, Yongchao; Gou, Xuxu; Huang, Chen; Shi, Zhiao; Wen, Bo; Korchina, Viktoriya; Gibbs, Richard A.; Muzny, Donna M.; Doddapaneni, Harshavardhan; Dobrolecki, Lacey E.; Rodriguez, Henry; Robles, Ana I.; Hiltke, Tara; Lewis, Michael T.; Nangia, Julie R.; Shafaee, Maryam Nemati; Li, Shunqiang; Hagemann, Ian S.; Hoog, Jeremy; Lim, Bora; Osborne, C. Kent; Mani, D. R.; Gillette, Michael A.; Zhang, Bing; Echeverria, Gloria V.; Miles, George; Rimawi, Mothaffar F.; Carr, Steven A.; Ademuyiwa, Foluso O.; Satpathy, Shankha; Ellis, Matthew J. 分享 收藏
Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer 多抗原靶向T细胞疗法治疗复发/难治性乳腺癌 Hoyos, Valentina; Vasileiou, Spyridoula; Kuvalekar, Manik; Watanabe, Ayumi; Tzannou, Ifigeneia; Velazquez, Yovana; French-Kim, Matthew; Leung, Wingchi; Lulla, Suhasini; Robertson, Catherine; Foreman, Claudette; Wang, Tao; Bulsara, Shaun; Lapteva, Natalia; Grilley, Bambi; Ellis, Matthew; Osborne, Charles Kent; Coscio, Angela; Nangia, Julie; Heslop, Helen E.; Rooney, Cliona M.; Vera, Juan F.; Lulla, Premal; Rimawi, Mothaffar; Leen, Ann M. 分享 收藏
Resistance to next generation tyrosine kinase inhibitors (TKIs) in HER2-positive breast cancer (BC): Role of HER and PIK3CA mutations and development of new treatment strategies and study models Bose, Sreyashree; Mistry, Ragini; Liu, Chia Chia; Nanda, Sarmistha; Qin, Lanfang; Selenica, Pier; Gazzo, Andrea; Zhu, Yingjie; Mancini, Michael A.; Stossi, Fabio; Diala, Irmina; Eli, Lisa D.; Weigelt, Britta; Reis-Filho, Jorge S.; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel; Veeraraghavan, Jamunarani 分享 收藏
Genetic assessment of hereditary breast and ovarian cancer in the Smith Clinic: A 10-year, single center experience Higashiyama, Nicole; Bulsara, Shaun; Hilsenbeck, Susan; Tran, Tiffaney; Brown, Ria; Fang, Mary; Sullivan, Cathy; Garza, Georgiann; Shafaee, Maryam Nemati; Osborne, C. Kent; Rimawi, Mothaffar; Nangia, Julie 分享 收藏
Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models Veeraraghavan, Jamunarani; Gutierrez, Carolina; Sethunath, Vidyalakshmi; Mehravaran, Sepideh; Giuliano, Mario; Shea, Martin J.; Mitchell, Tamika; Wang, Tao; Nanda, Sarmistha; Pereira, Resel; Davis, Robert; Goutsouliak, Kristina; Qin, Lanfang; De Angelis, Carmine; Diala, Irmina; Lalani, Alshad S.; Nagi, Chandandeep; Hilsenbeck, Susan G.; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel 分享 收藏
HER2-enriched subtype and pathological complete response in HER2-positive breast cancer: A systematic review and meta-analysis Schettini, Francesco; Pascual, Tomas; Conte, Benedetta; Chic, Nuria; Braso-Maristany, Fara; Galvan, Patricia; Martinez, Olga; Adamo, Barbara; Vidal, Maria; Munoz, Montserrat; Fernandez-Martinez, Aranzazu; Rognoni, Carla; Griguolo, Gaia; Guarneri, Valentina; Conte, Pier Franco; Locci, Mariavittoria; Brase, Jan C.; Gonzalez-Farre, Blanca; Villagrasa, Patricia; De Placido, Sabino; Schiff, Rachel; Veeraraghavan, Jamunarani; Rimawi, Mothaffar F.; Osborne, C. Kent; Pernas, Sonia; Perou, Charles M.; Carey, Lisa A.; Prat, Aleix 分享 收藏
Analytical validation and prognostic potential of an automated digital scoring protocol for Ki67: An International Ki67 Working Group study Acs, Balazs; Leung, Samuel C. Y.; Kidwell, Kelley M.; Arun, Indu; Augulis, Renaldas; Badve, Sunil S.; Bai, Yalai; Bane, Anita L.; Bartlett, John M. S.; Bayani, Jane; Bigras, Gilbert; Blank, Annika; Borgquist, Signe; Buikema, Henk; Chang, Martin C.; Dietz, Robin L.; Dodson, Andrew; Ehinger, Anna; Fineberg, Susan; Focke, Cornelia M.; Gao, Dongxia; Gown, Allen M.; Gutierrez, Carolina; Hartman, Johan; Hugh, Judith C.; Kos, Zuzana; Laenkholm, Anne-Vibeke; Laurinavicius, Arvydas; Levenson, Richard M.; Mahboubi-Ardakani, Rustin; Mastropasqua, Mauro G.; Moriya, Takuya; Nofech-Mozes, Sharon; Osborne, C. Kent; Pantanowitz, Liron; Penault-Llorca, Frederique M.; Piper, Tammy; Quintayo, Mary Anne; Rau, Tilman T.; Reinhard, Stefan; Robertson, Stephanie; Sakatani, Takashi; Salgado, Roberto; Spears, Melanie; Tarczynski, Jane S.; Sugie, Tomoharu; van der Vegt, Bert; Viale, Giuseppe; Virk, Shakeel; Zabaglo, Lila A.; Hayes, Daniel F.; Dowsett, Mitch; Nielsen, Torsten O.; Rimm, David L. 分享 收藏
Integrative cistromic/transcriptomic profiling identifies a high FOXA1/ER-activated pro-metastatic secretome in endocrine-resistant breast cancer Fu, Xiaoyong; Pereira, Resel; De Angelis, Carmine; Nanda, Sarmistha; Qin, Lanfang; Shea, Martin J.; Mitchell, Tamika; Veeraraghavan, Jamunarani; Sethunath, Vidyalakshmi; Gutierrez, Carolina; Gyorffy, Balazs; Cohen, Ofir; Wagle, Nikhil; Nardone, Agostina; Jeselsohn, Rinath; Brown, Myles; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel 分享 收藏
Identification of a high FOXA1-induced pro-metastatic enhancer signature in endocrine-resistant and metastatic breast cancer Fu, Xiaoyong; Pereira, Resel; De Angelis, Carmine; Nanda, Sarmistha; Qin, Lanfang; Veeraraghavan, Jamunarani; Selenica, Pier; Weigelt, Britta; Reis-Filho, Jorge S.; Nardone, Agostina; Jeselsohn, Rinath; Brown, Myles; Rimawi, Mothaffar F.; Osborne, Ckent; Schiff, Rachel 分享 收藏
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FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer FOXA1上调促进内分泌耐药乳腺癌增强子和转录重编程 Fu, Xiaoyong; Pereira, Resel; De Angelis, Carmine; Veeraraghavan, Jamunarani; Nanda, Sarmistha; Qin, Lanfang; Cataldo, Maria L.; Sethunath, Vidyalakshmi; Mehravaran, Sepideh; Gutierrez, Carolina; Chamness, Gary C.; Feng, Qin; O'Malley, Bert W.; Selenica, Pier; Weigelt, Britta; Reis-Filho, Jorge S.; Cohen, Ofir; Wagle, Nikhil; Nardonek, Agostina; Jeselsohn, Rinath; Brown, Myles; Rimawi, Mothaffar F.; Osborne, C. Kent; Schiff, Rachel 分享 收藏
A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer Thangavel, Hariprasad; De Angelis, Carmine; Vasaikar, Suhas; Bhat, Raksha; Jolly, Mohit Kumar; Nagi, Chandandeep; Creighton, Chad J.; Chen, Fengju; Dobrolecki, Lacey E.; George, Jason T.; Kumar, Tanya; Abdulkareem, Noor Mazin; Mao, Sufeng; Nardone, Agostina; Rimawi, Mothaffar; Osborne, C. Kent; Lewis, Michael T.; Levine, Herbert; Zhang, Bing; Schiff, Rachel; Giuliano, Mario; Trivedi, Meghana, V 分享 收藏
A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+breast cancer Veeraraghavan, J.; De Angelis, C.; Mao, R.; Wang, T.; Herrera, S.; Pavlick, A. C.; Contreras, A.; Nuciforo, P.; Mayer, I. A.; Forero, A.; Nanda, R.; Goetz, M. P.; Chang, J. C.; Wolff, A. C.; Krop, I. E.; Fuqua, S. A. W.; Prat, A.; Hilsenbeck, S. G.; Weigelt, B.; Reis-Filho, J. S.; Gutierrez, C.; Osborne, C. K.; Rimawi, M. F.; Schiff, R. 分享 收藏
HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade Prat, Aleix; Pascual, Tomas; De Angelis, Carmine; Gutierrez, Carolina; Llombart-Cussac, Antonio; Wang, Tao; Cortes, Javier; Rexer, Brent; Pare, Laia; Forero, Andres; Wolff, Antonio C.; Morales, Serafin; Adamo, Barbara; Braso-Maristany, Fara; Vidal, Maria; Veeraraghavan, Jamunarani; Krop, Ian; Galvan, Patricia; Pavlick, Anne C.; Bermejo, Begona; Izquierdo, Miguel; Rodrik-Outmezguine, Vanessa; Reis-Filho, Jorge S.; Hilsenbeck, Susan G.; Oliveira, Mafalda; Vittoria Dieci, Maria; Griguolo, Gaia; Fasani, Roberta; Nuciforo, Paolo; Parker, Joel S.; Conte, PierFranco; Schiff, Rachel; Guarneri, Valentina; Osborne, C. Kent; Rimawi, Mothaffar F. 分享 收藏
Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis Ramirez, Arturo B.; Bhat, Raksha; Sahay, Debashish; De Angelis, Carmine; Thangavel, Hariprasad; Hedayatpour, Sina; Dobrolecki, Lacey E.; Nardone, Agostina; Giuliano, Mario; Nagi, Chandandeep; Rimawi, Mothaffar; Osborne, C. Kent; Lewis, Michael T.; Stilwell, Jackie L.; Kaldjian, Eric P.; Schiff, Rachel; Trivedi, Meghana V. 分享 收藏
The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance Nardone, Agostina; Weir, Hazel; Delpuech, Oona; Brown, Henry; De Angelis, Carmine; Cataldo, Maria Letizia; Fu, Xiaoyong; Shea, Martin J.; Mitchell, Tamika; Veeraraghavan, Jamunarani; Nagi, Chandandeep; Pilling, Mark; Rimawi, Mothaffar F.; Trivedi, Meghana; Hilsenbeck, Susan G.; Chamness, Gary C.; Jeselsohn, Rinath; Osborne, C. Kent; Schiff, Rachel 分享 收藏
Cyclin E1 and Rb modulation as common events at time of resistance to palbociclib in hormone receptor-positive breast cancer Guarducci, Cristina; Bonechi, Martina; Benelli, Matteo; Biagioni, Chiara; Boccalini, Giulia; Romagnoli, Dario; Verardo, Roberto; Schiff, Rachel; Osborne, C. Kent; De Angelis, Carmine; Di Leo, Angelo; Malorni, Luca; Migliaccio, Ilenia 分享 收藏
Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer Nair, Amritha; Chung, Hsiang-Ching; Sun, Tingting; Tyagi, Siddhartha; Dobrolecki, Lacey E.; Dominguez-Vidana, Rocio; Kurley, Sarah J.; Orellana, Mayra; Renwick, Alexander; Henke, David M.; Katsonis, Panagiotis; Schmitt, Earlene; Chan, Doug W.; Li, Hui; Mao, Sufeng; Petrovic, Ivana; Creighton, Chad J.; Gutierrez, Carolina; Dubrulle, Julien; Stossi, Fabio; Tyner, Jeffrey W.; Lichtarge, Olivier; Lin, Charles Y.; Zhang, Bing; Scott, Kenneth L.; Hilsenbeck, Susan G.; Sun, Jinpeng; Yu, Xiao; Osborne, C. Kent; Schiff, Rachel; Christensen, James G.; Shields, David J.; Rimawi, Mothaffar F.; Ellis, Matthew J.; Shaw, Chad A.; Lewis, Michael T.; Westbrook, Thomas F. 分享 收藏
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