Dieter Langosch - Publications, H-index & Citations

Dieter Langosch

technical university of munich

45H指数

152论文数

8.0K被引数

收录论文 57

发表时间

Conformational Flexibility of Transmembrane Helices: How it Works and Where it Matters 跨膜螺旋的构象柔性：其作用机制及重要性所在

Chemical Reviews

IF55.8

2026-02-01

PREAI

Langosch, Dieter

Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain

FASEB JOURNAL

IF4.2

2024-01-26

OAAI

Assfalg, Marlene; Guener, Goekhan; Mueller, Stephan A.; Breimann, Stephan; Langosch, Dieter; Muhle-Goll, Claudia; Frishman, Dmitrij; Steiner, Harald; Lichtenthaler, Stefan F.

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-05-01

OAAI

Schmidt, Fabian C.; Fitz, Katja; Feilen, Lukas P.; Okochi, Masayasu; Steiner, Harald; Langosch, Dieter

Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase

COMMUNICATIONS BIOLOGY

IF5.1

2023-02-15

OAAI

Werner, Nadine T. T.; Hoegel, Philipp; Guener, Gokhan; Stelzer, Walter; Wozny, Manfred; Assfalg, Marlene; Lichtenthaler, Stefan F.; Steiner, Harald; Langosch, Dieter

Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage

SCIENTIFIC REPORTS

IF3.9

2022-12-05

OAAI

Papadopoulou, Alkmini A.; Stelzer, Walter; Silber, Mara; Schlosser, Christine; Spitz, Charlotte; Haug-Kroeper, Martina; Straub, Tobias; Mueller, Stephan A.; Lichtenthaler, Stefan F.; Muhle-Goll, Claudia; Langosch, Dieter; Fluhrer, Regina

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity

EMBO MOLECULAR MEDICINE

IF8.3

2022-09-07

OAAI

Guener, Goekhan; Assfalg, Marlene; Zhao, Kai; Dreyer, Tobias; Lahiri, Shibojyoti; Lo, Yun; Slivinschi, Bianca Ionela; Imhof, Axel; Jocher, Georg; Strohm, Laura; Behrends, Christian; Langosch, Dieter; Bronger, Holger; Nimsky, Christopher; Bartsch, Joerg W.; Riddell, Stanley R.; Steiner, Harald; Lichtenthaler, Stefan F.

Determining the Stoichiometry of Small Protein Oligomers Using Steady-State Fluorescence Anisotropy

BIOPHYSICAL JOURNAL

IF3.1

2020-07-01

OAAI

Heckmeier, Philipp J.; Agam, Ganesh; Teese, Mark G.; Hoyer, Maria; Stehle, Ralf; Lamb, Don C.; Langosch, Dieter

Identifying ionic interactions within a membrane using BLaTM, a genetic tool to measure homo- and heterotypic transmembrane helix-helix interactions (vol 7, 43476, 2017)

SCIENTIFIC REPORTS

IF3.9

2020-04-24

OAAI

Schanzenbach, Christoph; Schmidt, Fabian C.; Breckner, Patrick; Teese, Mark G.; Langosch, Dieter

Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage 调节APP跨膜结构域中的铰链柔性会改变 γ-分泌酶的切割

BIOPHYSICAL JOURNAL

IF3.1

2019-06-01

OAAI

Goetz, Alexander; Mylonas, Nadine; Hoegel, Philipp; Silber, Mara; Heinel, Hannes; Menig, Simon; Vogel, Alexander; Feyrer, Hannes; Huster, Daniel; Luy, Burkhard; Langosch, Dieter; Scharnagl, Christina; Muhle-Goll, Claudia; Kamp, Frits; Steiner, Harald

Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer's Disease Mutant of APP

SCIENTIFIC REPORTS

IF3.9

2019-03-29

OAAI

Goetz, Alexander; Hoegel, Philipp; Silber, Mara; Chaitoglou, Iro; Luy, Burkhard; Muhle-Goll, Claudia; Scharnagl, Christina; Langosch, Dieter

The Metastable XBP1u Transmembrane Domain Defines Determinants for Intramembrane Proteolysis by Signal Peptide Peptidase

CELL REPORTS

IF6.9

2019-03-01

OAAI

Yuecel, Sara Suna; Stelzer, Walter; Lorenzoni, Alessandra; Wozny, Manfred; Langosch, Dieter; Lemberg, Marius K.