Che‐Hong Chen - Publications, H-index & Citations

Che‐Hong Chen

Department of Chemical and Systems Biology

34H指数

136论文数

4.2K被引数

收录论文 53

发表时间

Exploratory assessment of the potential protective effects of Kampo treatment against low dose medical radiation: a single arm prospective observational study 对低剂量医疗辐射下汉方治疗潜在保护作用的探索性评估：一项单臂前瞻性观察研究

Frontiers in Pharmacology

IF4.8

2026-08-14

OAAI

HL Hongyang Li †; YK Yuri Kawashima †; LL Lian Liang; CC Che-Hong Chen; NQ Ngo Quang Trung; GL Gloriamaris Loy Caraos; YK Yasuha Kinugasa; KF Kurumi Fujioka; CS Chiemi Sakai; AA Akihiko Adachi; JS Jiying Sun; KA Kazuo Awai; YO Yasushi Orihashi; YK Yasuki Kihara; DM Daria Mochly-Rosen; ST Satoshi Tashiro; KO Keiko Ogawa-Ochiai

Common human ALDH1B1 and ALDH2 variants increase neuroinflammatory response to a single ethanol dose in mice 常见的人类ALDH1B1和ALDH2变异体可增加小鼠对单次乙醇剂量的神经炎症反应

Science Advances

IF12.5

2026-06-24

OAAI

Takuya Seike; Ruda Prestes e Albuquerque; Julio Cesar Batista Ferreira; Che-Hong Chen; Daria Mochly-Rosen

THE ASSOCIATION BETWEEN SEMEN PARAMETERS AND SLEEP QUALITY IN A COHORT OF HEALTHY MEN 精液参数与睡眠质量在健康男性队列中的关联

Journal of Urology

IF6.8

2026-05-01

PREAI

Negri, Fausto; Basran, Satvir S.; Langroudi, Ashkan P.; Sellke, Nicholas C.; Li, Shufeng; Montorsi, Francesco; Salonia, Andrea; Chen, Che-Hong; Mosley-Rosen, Daria; Eisenberg, Michael L.

Low Alanine Aminotransferase Levels in Alcohol Consuming Male Subjects, Carriers of the Common ALDH2 Deficient Variant, ALDH2*2 饮酒男性受试者中丙氨酸氨基转移酶水平较低，携带常见ALDH2缺乏变异型ALDH2*2

Hepatology Research

IF3.4

2025-10-27

OAAI

Takuya Seike; Che-Hong Chen; Eishiro Mizukoshi; Daria Mochly-Rosen

Corrigendum: Novel and prevalent non-East Asian ALDH2 variants; implications for global susceptibility to aldehydes’ toxicity EBioMedicine (2020) – doi: 10.1016/j.ebiom.2020.102753 勘误：新颖且普遍的非东亚人群ALDH2变异；对醛类毒性的全球易感性的影响 EBioMedicine (2020) – doi: 10.1016/j.ebiom.2020.102753

eBioMedicine

IF10.8

2025-06-12

OAAI

Che-Hong Chen; Julio C.B. Ferreira; Amit U. Joshi; Matthew C. Stevens; Sin-Jin Li; Jade H.-M Hsu; Rory Maclean; Nikolas D. Ferreira; Pilar R. Cervantes; Diana D. Martinez; Fernando L. Barrientos; Gibran H.R. Quintanares; Daria Mochly-Rosen

Suppression of aldehyde dehydrogenase 2 in kidney proximal tubules contributes to kidney fibrosis through Transforming Growth Factor-βsignaling 醛脱氢酶2在肾近端小管中的抑制通过转化生长因子-β信号通路促进肾脏纤维化。

KIDNEY INTERNATIONAL

IF12.6

2025-01-01

PREAI

Chiu, I-Jen; Ajay, Amrendra K.; Chen, Che-Hong; Jadhav, Shreyas; Zhao, Li; Cao, Minghua; Ding, Yan; Shah, Kavya M.; Shah, Sujal I.; Hsiao, Li-Li

Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1 (vol 18, pg 1065, 2022)

NATURE CHEMICAL BIOLOGY

IF13.7

2024-12-09

OAAI

Feng, Zhiping; Hom, Marisa E.; Bearrood, Thomas E.; Rosenthal, Zachary C.; Fernandez, Daniel; Ondrus, Alison E.; Gu, Yuchao; Mccormick, Aaron K.; Tomaske, Madeline G.; Marshall, Cody R.; Kline, Toni; Chen, Che-Hong; Mochly-Rosen, Daria; Kuo, Calvin J.; Chen, James K.

A changing landscape of alcohol consumption in the women

LIVER INTERNATIONAL

IF5.2

2024-07-22

PREAI

Chiu, Chong-Chi; Chen, Che-Hong; Chiu, Si-Wai Vivian; Lin, Jaw-Town

Cleavage of Hsp70.1 causes lysosomal cell death under stress conditions Hsp70.1的裂解在应激条件下导致溶酶体细胞死亡

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2024-05-27

OAAI

Yamashima, Tetsumori; Mochly-Rosen, Daria; Wakatsuki, Soichi; Mizukoshi, Eishiro; Seike, Takuya; Larus, Isabel Maria; Chen, Che-Hong; Takemura, Miho; Saito, Hisashi; Ohashi, Akihiro

ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment ALDH2功能障碍和酒精在肿瘤干细胞富集中的协同作用

CARCINOGENESIS

IF2.9

2023-11-18

OAAI

Flashner, Samuel; Shimonosono, Masataka; Tomita, Yasuto; Matsuura, Norihiro; Ohashi, Shinya; Muto, Manabu; Klein-Szanto, Andres J.; Diehl, J. Alan; Chen, Che-Hong; Mochly-Rosen, Daria; Weinberg, Kenneth, I; Nakagawa, Hiroshi

4-Hydroxynonenal impairs miRNA maturation in heart failure via Dicer post-translational modification 4-羟基壬烯醛通过Dicer翻译后修饰损害心力衰竭中miRNA的成熟

EUROPEAN HEART JOURNAL

IF35.6

2023-11-07

OAAI

Kiyuna, Ligia A.; Candido, Darlan S.; Bechara, Luiz R. G.; Jesus, Itamar C. G.; Ramalho, Lisley S.; Krum, Barbara; Albuquerque, Ruda P.; Campos, Juliane C.; Bozi, Luiz H. M.; Zambelli, Vanessa O.; Alves, Ariane N.; Campolo, Nicolas; Mastrogiovanni, Mauricio; Bartesaghi, Silvina; Leyva, Alejandro; Duran, Rosario; Radi, Rafael; Arantes, Guilherme M.; Cunha-Neto, Edecio; Mori, Marcelo A.; Chen, Che-Hong; Yang, Wenjin; Mochly-Rosen, Daria; MacRae, Ian J.; Ferreira, Ludmila R. P.; Ferreira, Julio C. B.

A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators 一种常见的东亚人群ALDH2突变会导致代谢紊乱，并影响ALDH2激活剂的治疗效果。

NATURE COMMUNICATIONS

IF15.7

2023-09-25

OAAI

Chang, Yi-Cheng; Lee, Hsiao-Lin; Yang, Wenjin; Hsieh, Meng-Lun; Liu, Cai-Cin; Lee, Tung-Yuan; Huang, Jing-Yong; Nong, Jiun-Yi; Li, Fu-An; Chuang, Hsiao-Li; Ding, Zhi-Zhong; Su, Wei-Lun; Chueh, Li-Yun; Tsai, Yi-Ting; Chen, Che-Hong; Mochly-Rosen, Daria; Chuang, Lee-Ming

Implication of the cooking oil-peroxidation product hydroxynonenal for Alzheimer's disease 食用油过氧化产物羟壬烯对阿尔茨海默氏病的影响

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2023-08-25

OAAI

Yamashima, Tetsumori; Seike, Takuya; Mochly-Rosen, Daria; Chen, Che-Hong; Kikuchi, Mitsuru; Mizukoshi, Eishiro

Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer's disease 常见ALDH2失活突变和饮酒对阿尔茨海默病的影响

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2023-08-24

OAAI

Seike, Takuya; Chen, Che-Hong; Mochly-Rosen, Daria

Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism 酒精依赖患者戒断后神经丝轻链的变化及ALDH2多态性的遗传效应

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

IF3.7

2023-06-14

PREAI

Huang, Ming-Chyi; Tu, Hsueh-Yuan; Chung, Ren-Hua; Kuo, Hsiang-Wei; Liu, Tung-Hsia; Chen, Che-Hong; Mochly-Rosen, Daria; Liu, Yu-Li

A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice 一种常见的东亚乙醛脱氢酶2*2变体在小鼠慢性轻度至中度饮酒时促进室性心律失常

COMMUNICATIONS BIOLOGY

IF5.1

2023-06-06

OAAI

Lee, An-Sheng; Sung, Yen-Ling; Pan, Szu-Hua; Sung, Kuo-Tzu; Su, Cheng-Huang; Ding, Shiao-Li; Lu, Ying-Jui; Hsieh, Chin-Ling; Chen, Yun-Fang; Liu, Chuan-Chuan; Chen, Wei-Yu; Chen, Xuan-Ren; Chung, Fa-Po; Wang, Shih-Wei; Chen, Che-Hong; Mochly-Rosen, Daria; Hung, Chung-Lieh; Yeh, Hung-, I; Lin, Shien-Fong

A Model of Public Health Campaign on the Awareness of Alcohol Flushing and Prevention of Upper Aerodigestive Tract Cancers in East Asia 东亚地区对酒精冲洗和预防上消化道癌症的认识的公共卫生运动模型

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

IF3.4

2023-06-01

PREAI

Chen, Che-Hong; Mochly-Rosen, Daria; Hou, Su-I

SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant SGLT2抑制剂改善与常见ALDH2酒精潮红变体相关的内皮功能障碍

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-01-25

OAAI

Guo, Hongchao; Yu, Xuan; Liu, Yu; Paik, David T.; Justesen, Johanne Marie; Chandy, Mark; Jahng, James W. S.; Zhang, Tiejun; Wu, Weijun; Rwere, Freeborn; Zhao, Shane Rui; Pokhrel, Suman; V. Shivnaraine, Rabindra; Mukherjee, Souhrid; Simon, Daniel J.; Manhas, Amit; Zhang, Angela; Chen, Che-Hong; Rivas, Manuel A.; Gross, Eric R.; Mochly-Rosen, Daria; Wu, Joseph C.

The Association between Monthly, Yearly, and Lifetime Cannabis Use, and Semen Parameters in Asian-American Men

WORLD JOURNAL OF MENS HEALTH

IF4.1

2023-01-01

OAAI

Belladelli, Federico; Chen, Tony; Basran, Satvir; Greenberg, Daniel R.; Del Giudice, Francesco; Mulloy, Evan; Chen, Che-Hong; Cheng, Yu-Sheng; Salonia, Andrea; Eisenberg, Michael L.

ALDH7A1 rs12514417 polymorphism may increase ischemic stroke risk in alcohol-exposed individuals

NUTRITION & METABOLISM

IF4.1

2022-10-18

OAAI

Lin, Chun-Hsiang; Nfor, Oswald Ndi; Ho, Chien-Chang; Hsu, Shu-Yi; Tantoh, Disline Manli; Liaw, Yi-Chia; Mochly-Rosen, Daria; Chen, Che-Hong; Liaw, Yung-Po

研究方向