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A systems pharmacology model for gene therapy in sickle cell disease Zheng, Bo; Wille, Lucia; Peppel, Karsten; Hagen, David; Matteson, Andrew; Ahlers, Jeffrey; Schaff, James; Hua, Fei; Yuraszeck, Theresa; Cobbina, Enoch; Apgar, Joshua F.; Burke, John M.; Roberts, John; Das, Raibatak 分享 收藏
S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling Lerchenmueller, Carolin; Heissenberg, Julian; Damilano, Federico; Bezzeridis, Vassilios J.; Kraemer, Isabel; Bochaton-Piallat, Marie-Luce; Hirschberg, Kristof; Busch, Martin; Katus, Hugo A.; Peppel, Karsten; Rosenzweig, Anthony; Busch, Hauke; Boerries, Melanie; Most, Patrick 分享 收藏
S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction Ritterhoff, Julia; Voelkers, Mirko; Seitz, Andreas; Spaich, Kristin; Gao, Erhe; Peppel, Karsten; Pleger, Sven T.; Zimmermann, Wolfram H.; Friedrich, Oliver; Fink, Rainer H. A.; Koch, Walter J.; Katus, Hugo A.; Most, Patrick 分享 收藏
S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4 Rohde, David; Schoen, Christoph; Boerries, Melanie; Didrihsone, Ieva; Ritterhoff, Julia; Kubatzky, Katharina F.; Voelkers, Mirko; Herzog, Nicole; Maehler, Mona; Tsoporis, James N.; Parker, Thomas G.; Linke, Bjoern; Giannitsis, Evangelos; Gao, Erhe; Peppel, Karsten; Katus, Hugo A.; Most, Patrick 分享 收藏
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S100A1 Deficiency Impairs Postischemic Angiogenesis Via Compromised Proangiogenic Endothelial Cell Function and Nitric Oxide Synthase Regulation S100A1缺乏通过受损的促血管生成内皮细胞功能和一氧化氮合酶调节来损害缺血后血管生成 Most, Patrick; Lerchenmueller, Carolin; Rengo, Giuseppe; Mahlmann, Adrian; Ritterhoff, Julia; Rohde, David; Goodman, Chelain; Busch, Cornelius J.; Laube, Felix; Heissenberg, Julian; Pleger, Sven T.; Weiss, Norbert; Katus, Hugo A.; Koch, Walter J.; Peppel, Karsten 分享 收藏
G Protein-Coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-Transmembrane Receptors Wu, Jiao-Hui; Zhang, Lisheng; Fanaroff, Alexander C.; Cai, Xinjiang; Sharma, Krishn C.; Brian, Leigh; Exum, Sabrina T.; Shenoy, Sudha K.; Peppel, Karsten; Freedman, Neil J. 分享 收藏
Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: restoration by intravascular human β2-adrenoceptor gene transfer and role of NFκB and CREB transcription factors Ciccarelli, Michele; Sorriento, Daniela; Cipolletta, Ersilia; Santulli, Gaetano; Fusco, Anna; Zhou, Rui-Hai; Eckhart, Andrea D.; Peppel, Karsten; Koch, Walter J.; Trimarco, Bruno; Iaccarino, Guido 分享 收藏
The Inotropic Peptide βARKct Improves βAR Responsiveness in Normal and Failing Cardiomyocytes Through Gβγ-Mediated L-Type Calcium Current Disinhibition Voelkers, Mirko; Weidenhammer, Christian; Herzog, Nicole; Qiu, Gang; Spaich, Kristin; von Wegner, Frederic; Peppel, Karsten; Mueller, Oliver J.; Schinkel, Stefanie; Rabinowitz, Joseph E.; Hippe, Hans-Joerg; Brinks, Henriette; Katus, Hugo A.; Koch, Walter J.; Eckhart, Andrea D.; Friedrich, Oliver; Most, Patrick 分享 收藏
Human umbilical cord blood endothelial progenitor cells decrease vein graft neointimal hyperplasia in SCID mice Zhu, Shoukang; Malhotra, Anuj; Zhang, Lisheng; Deng, Shanming; Zhang, Taifang; Freedman, Neil J.; Storms, Robert; Peppel, Karsten; Goldschmidt-Clermont, Pascal J.; Dong, Chunming 分享 收藏
Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies Zhang, Lisheng; Connelly, Jessica J.; Peppel, Karsten; Brian, Leigh; Shah, Svati H.; Nelson, Sarah; Crosslin, David R.; Wang, Tianyuan; Allen, Andrew; Kraus, William E.; Gregory, Simon G.; Hauser, Elizabeth R.; Freedman, Neil J. 分享 收藏
β-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration Kim, Jihee; Zhang, Lisheng; Peppel, Karsten; Wu, Jiao-Hui; Zidar, David A.; Brian, Leigh; DeWire, Scott M.; Exum, Sabrina T.; Lefkowitz, Robert J.; Freedman, Neil J. 分享 收藏
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Substrate specificities of G protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function Vinge, Leif Erik; Andressen, Kjetil W.; Attramadal, Toril; Andersen, Geir Oystein; Ahmed, Mohammed Shakil; Peppel, Karsten; Koch, Walter J.; Freedman, Neil J.; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjorn; Attramadal, Havard 分享 收藏
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Regulation of the platelet-derived growth factor receptor-β by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2 Wu, Jiao-Hui; Goswami, Robi; Cai, Xinjiang; Exum, Sabrina T.; Huang, Xuewei; Zhang, Lisheng; Brian, Leigh; Premont, Richard T.; Peppel, Karsten; Freedman, Neil J. 分享 收藏
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