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A Randomized, Double-Blind, Phase 3 Safety and Efficacy Study of Ridinilazole Versus Vancomycin for Treatment of Clostridioides difficile Infection: Clinical Outcomes With Microbiome and Metabolome Correlates of Response Ridinilazole与万古霉素治疗艰难梭菌感染的随机,双盲,3期安全性和有效性研究: 微生物组和代谢组与反应相关的临床结果 Okhuysen, Pablo C.; Ramesh, Mayur S.; Louie, Thomas; Kiknadze, Nino; Torre-Cisneros, Julian; de Oliveira, Claudia Murta; Van Steenkiste, Christophe; Stychneuskaya, Alena; Garey, Kevin W.; Garcia-Diaz, Julia; Li, Jianling; Duperchy, Esther; Chang, Betty Y.; Sukbuntherng, Juthamas; Montoya, Jose G.; Styles, Lori; Clow, Fong; James, Danelle; Dubberke, Erik R.; Wilcox, Mark 分享 收藏
Prevalence of Comorbid Factors in Patients With Recurrent Clostridioides difficile Infection in ECOSPOR III, a Randomized Trial of an Oral Microbiota-Based Therapeutic Berenson, Charles S.; Lashner, Bret; Korman, Louis Y.; Hohmann, Elizabeth; Deshpande, Abhishek; Louie, Thomas J.; Sims, Matthew; Pardi, Darrell; Kraft, Colleen S.; Wang, Elaine E. L.; Cohen, Stuart H.; Feuerstadt, Paul; Oneto, Caterina; Misra, Bharat; Pullman, John; De, Ananya; Memisoglu, Asli; Lombardi, David A.; Hasson, Brooke R.; McGovern, Barbara H.; von Moltke, Lisa; Lee, Christine H. 分享 收藏
Redefining Clostridioides difficile infection antibiotic response and clinical outcomes Gonzales-Luna, Anne J.; Skinner, Andrew M.; Alonso, Carolyn D.; Bouza, Emilio; Cornely, Oliver A.; de Meij, Tim G. J.; Drew, Richard J.; Garey, Kevin W.; Gerding, Dale N.; Johnson, Stuart; Kahn, Stacy A.; Kato, Haru; Kelly, Ciaran P.; Kelly, Colleen R.; Kociolek, Larry K.; Kuijper, Ed J.; Louie, Thomas; Riley, Thomas, V; Sandora, Thomas J.; Vehreschild, Maria J. G. T.; Wilcox, Mark H.; Dubberke, Erik R. 分享 收藏
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Safety of fecal microbiota, live-jslm (REBYOTA™) in individuals with recurrent Clostridioides difficile infection: data from five prospective clinical trials Lee, Christine; Louie, Thomas; Bancke, Lindy; Guthmueller, Beth; Harvey, Adam; Feuerstadt, Paul; Khanna, Sahil; Orenstein, Robert; Dubberke, Erik R. R. 分享 收藏
VE303, a Defined Bacterial Consortium, for Prevention of Recurrent Clostridioides difficile Infection A Randomized Clinical Trial VE303,一个定义的细菌联盟,用于预防复发性艰难梭菌感染随机临床试验 Louie, Thomas; Golan, Yoav; Khanna, Sahil; Bobilev, Dmitri; Erpelding, Nathalie; Fratazzi, Candida; Carini, Meg; Menon, Rajita; Ruisi, Mary; Norman, Jason M. M.; Faith, Jeremiah J. J.; Olle, Bernat; Li, Minran; Silber, Jeffrey L. L.; Pardi, Darrell S. S. 分享 收藏
Metabolic independence drives gut microbial colonization and resilience in health and disease 代谢独立性驱动肠道微生物定植和恢复健康和疾病 Watson, Andrea R.; Fuessel, Jessika; Veseli, Iva; DeLongchamp, Johanna Zaal; Silva, Marisela; Trigodet, Florian; Lolans, Karen; Shaiber, Alon; Fogarty, Emily; Runde, Joseph M.; Quince, Christopher; Yu, Michael K.; Soeylev, Arda; Morrison, Hilary G.; Lee, Sonny T. M.; Kao, Dina; Rubin, David T.; Jabri, Bana; Louie, Thomas; Eren, A. Murat 分享 收藏
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Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection (Oct, 10.1007/s40265-022-01797-x, 2022) Khanna, Sahil; Assi, Maha; Lee, Christine; Yoho, David; Louie, Thomas; Knapple, Whitfield; Aguilar, Humberto; Garcia-Diaz, Julia; Wang, Gary P.; Berry, Scott M.; Marion, Joe; Su, Xin; Braun, Tricia; Bancke, Lindy; Feuerstadt, Paul 分享 收藏
Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection RBX2660在PUNCH CD3中的疗效和安全性,这是一项III期,随机,双盲,安慰剂对照试验,采用贝叶斯主要分析来预防复发性艰难梭菌感染 Khanna, Sahil; Assi, Maha; Lee, Christine; Yoho, David; Louie, Thomas; Knapple, Whitfield; Aguilar, Humberto; Garcia-Diaz, Julia; Wang, Gary P.; Berry, Scott M.; Marion, Joe; Su, Xin; Braun, Tricia; Bancke, Lindy; Feuerstadt, Paul 分享 收藏
SER-109: An Oral Investigational Microbiome Therapeutic for Patients with Recurrent Clostridioides difficile Infection (rCDI) Khanna, Sahil; Sims, Matthew; Louie, Thomas J.; Fischer, Monika; LaPlante, Kerry; Allegretti, Jessica; Hasson, Brooke R.; Fonte, Allyson T.; McChalicher, Christopher; Ege, David S.; Bryant, Jessica A.; Straub, Timothy J.; Ford, Christopher B.; Henn, Matthew R.; Wang, Elaine E. L.; von Moltke, Lisa; Wilcox, Mark H. 分享 收藏
Detection and quantification of infectious severe acute respiratory coronavirus-2 in diverse clinical and environmental samples Lin, Yi-Chan; Malott, Rebecca J.; Ward, Linda; Kiplagat, Linet; Pabbaraju, Kanti; Gill, Kara; Berenger, Byron M.; Hu, Jia; Fonseca, Kevin; Noyce, Ryan S.; Louie, Thomas; Evans, David H.; Conly, John M. 分享 收藏
An open randomized multicentre Phase 2 trial to assess the safety of DAV132 and its efficacy to protect gut microbiota diversity in hospitalized patients treated with fluoroquinolones 一项开放随机多中心2期试验,评估DAV132的安全性及其对氟喹诺酮类药物治疗的住院患者肠道微生物多样性的保护作用 Vehreschild, Maria J. G. T.; Ducher, Annie; Louie, Thomas; Cornely, Oliver A.; Feger, Celine; Dane, Aaron; Varastet, Marina; Vitry, Fabien; de Gunzburg, Jean; Andremont, Antoine; Mentre, France; Wilcox, Mark H. 分享 收藏
Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection Associates With Functional Alterations in Circulating microRNAs Monaghan, Tanya M.; Seekatz, Anna M.; Markham, Nicholas O.; Yau, Tung On; Hatziapostolou, Maria; Jilani, Tahseen; Christodoulou, Niki; Roach, Brandi; Birli, Eleni; Pomenya, Odette; Louie, Thomas; Lacy, D. Borden; Kim, Peter; Lee, Christine; Kao, Dina; Polytarchou, Christos 分享 收藏
Saliva collected in universal transport media is an effective, simple and high-volume amenable method to detect SARS-CoV-2 Berenger, Byron M.; Conly, John M.; Fonseca, Kevin; Hu, Jia; Louie, Thomas; Schneider, Angela R.; Singh, Takshveer; Stokes, William; Ward, Linda; Zelyas, Nathan 分享 收藏
Impact of Seasonality and Influenza Rates on Interventions to Reduce Hospital-Acquired Clostridioides difficile Rates Leal, Jenine; Faris, Peter; Shen, Ye; Bresee, Lauren; Bush, Kathryn; Chow, Blanda; Dalton, Bruce; Fletcher, Jared; Hartman, Sara; Kaufman, Jaime; Kim, Joseph; Kothandaraman, Maitreyi; Kraft, Scott; Lamont, Nicole; Larios, Oscar; Manns, Braden; Missaghi, Bayan; Ocampo, Wrechelle; Poulin, Paule; Sabuda, Deana; Holroyd-Leduc, Jayna; Louie, Thomas; Conly, John 分享 收藏
Implementation Strategies of a Quality Improvement Initiative for Hospital-Acquired Clostridioides difficile Infection Prevention Lamont, Nicole; Bresee, Lauren; Bush, Kathryn; Chow, Blanda; Dalton, Bruce; Doolan, Cody; Faris, Peter; Fletcher, Jared; Hartman, Sara; Kaufman, Jaime; Khan, Maida; Kim, Joseph; Kothandaraman, Maitreyi; Kraft, Scott; Larios, Oscar; Leal, Jenine; Manns, Braden; Missaghi, Bayan; Ocampo, Wrechelle; Pillai, Dylan; Poulin, Paule; Sabuda, Deana; Shen, Ye; Louie, Thomas; Holroyd-Leduc, Jayna; Conly, John 分享 收藏