未登录 Real-time functional proteomics enhances therapeutic targeting in precision oncology molecular tumor boards 实时功能蛋白质组学增强了精准肿瘤学分子肿瘤委员会的靶向治疗。 Hunt, Allison L.; Randall, Jamie; Mansukhani, Mahesh M.; Nyberg, Kara; Nutcharoen, Aratara; Davis, Justin; Corgiat, Brian; Mueller, Claudius; Melvin, Savannah; Sharma, Meenakshi; Johnston, Laura; Swain, Whitney; Abulez, Tamara; Bateman, Nicholas W.; Maxwell, G. Larry; Deeken, John; Benyounes, Amin; Petricoin, Emanuel F.; Cannon, Timothy L.; Conrads, Thomas P. 分享 收藏
Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer Campbell, Michael J.; Wolf, Denise M.; Yau, Christina; Brown-Swigart, Lamorna; Wulfkuhle, Julie; Gallagher, Isela R.; Zhu, Zelos; Bolen, Jennifer; Vandenberg, Scott; Hoyt, Clifford; Mori, Hidetoshi; Borowsky, Alexander; Sit, Laura; Perlmutter, Jane; Asare, Smita M.; Nanda, Rita; Liu, Minetta C.; Yee, Douglas; Demichele, Angela M.; Hylton, Nola M.; Pusztai, Lajos; Berry, Donald A.; Hirst, Gillian L.; Petricoin, Emanuel F.; van't Veer, Laura; Esserman, Laura 分享 收藏
分享 收藏
Functional activation of the AKT-mTOR signalling axis in a real-world metastatic breast cancer cohort 现实世界转移性乳腺癌队列中akt-mtor信号轴的功能激活 Prasad, Deepika; Baldelli, Elisa; Blais, Edik M.; Davis, Justin; El Gazzah, Emna; Mueller, Claudius; Gomeiz, Alison; Ibrahim, Aisha; Newrekar, Avani Vinayak; Corgiat, Brian A.; Dunetz, Rick; Petricoin III, Emanuel F.; Wei, Qi; Pierobon, Mariaelena 分享 收藏
Proteomics based selection achieves complete response to HER2 therapy in HER2 IHC 0 breast cancer 基于蛋白质组学的选择在HER2 IHC 0乳腺癌中实现对HER2治疗的完全反应 Johnston, Laura E.; Randall, Jamie; Chouraichi, Safae; Luu, Mary; Hunt, Allison L.; Mauro, Lauren; Mueller, Claudius; Davis, Justin B.; Petricoin, Emanuel F.; Conrads, Thomas P.; Cannon, Timothy L.; Huynh, Jasmine 分享 收藏
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers 介质激酶抑制阻碍转录可塑性并阻止KRAS突变癌症对ERK/MAPK靶向治疗的抗性 Nussbaum, Daniel P.; Martz, Colin A.; Waters, Andrew M.; Barrera, Alejandro; Liu, Annie; Rutter, Justine C.; Cerda-Smith, Christian G.; Stewart, Amy E.; Wu, Chao; Cakir, Merve; Levandowski, Cecilia B.; Kantrowitz, David E.; Mccall, Shannon J.; Pierobon, Mariaelena; Petricoin III, Emanuel F.; Joshua Smith, J.; Reddy, Timothy E.; Der, Channing J.; Taatjes, Dylan J.; Wood, Kris C. 分享 收藏
Keratin 17 modulates the immune topography of pancreatic cancer 角蛋白17调节胰腺癌的免疫形貌 Delgado-Coka, Lyanne; Horowitz, Michael; Torrente-Goncalves, Mariana; Roa-Pena, Lucia; Leiton, Cindy V.; Hasan, Mahmudul; Babu, Sruthi; Fassler, Danielle; Oentoro, Jaymie; Bai, Ji-Dong K.; Petricoin III, Emanuel F.; Matrisian, Lynn M.; Blais, Edik Matthew; Marchenko, Natalia; Allard, Felicia D.; Jiang, Wei; Larson, Brent; Hendifar, Andrew; Chen, Chao; Abousamra, Shahira; Samaras, Dimitris; Kurc, Tahsin; Saltz, Joel; Escobar-Hoyos, Luisa F.; Shroyer, Kenneth R. 分享 收藏
分享 收藏
Investigating mechanisms of tumor eradication by blocking SIAH E3 ligase, a major tumor vulnerability, in EGFR/RAS-driven human cancer Baker, Jonathan M.; Howell, Andrew; Hannah, Ashleigh; Wulfkuhle, Julia; Stahr, Natalie; Gallagher, Rosa; Petricoin, Emanuel; Tang, Amy 分享 收藏
Optimization of digital pathology through laser capture microdissection with a 405 nm laser Philipson, Thomas; Howard, Marissa; Johnson, Kevin; Still, Amanda; Yunusov, Furkat; Petricoin, Emanuel; Espina, Virginia; Gonzalez, Noel; Carpino, Alan; Liotta, Lance 分享 收藏
Global and TNBC-specific biomarkers of sensitivity and resistance in early stage breast cancer from the I-SPY2 biomarker data compendium Bui, Tam Binh V.; Wolf, Denise M.; Gallagher, Rosa I.; Wulfkuhle, Julia; Yau, Christina; Brown-Swigart, Lamorna; Rosenbluth, Jennifer; Yee, Douglas; Hirst, Gillian L.; Esserman, Laura J.; Petricoin, Emanuel F.; Van't Veer, Laura J. 分享 收藏
IGF-1R protein pathway activation is associated with pathologic complete response to an anti-IGF-1R regimen (paclitaxel, ganitumab, and metformin) in the I-SPY2 neoadjuvant breast cancer trial Petricoin, Emanuel F.; Wolf, Denise M.; Yau, Christina; Wulfkuhle, Julia; Veer, Laura van T.; Gallagher, Rosa I.; Hirst, Gillian L.; Brown-Swigart, Lamorna; Esserman, Laura J.; Yee, Douglas 分享 收藏
An alternative to HER2 IHC 0/1+/2+status to predict which clinically HER2-negative patients will respond to anti-HER2 therapies: A rationale for the likely superiority of quantitative HER2 pathway RPPA measurements Wulfkuhle, Julia; Wolf, Denise M.; DeMichele, Angela; Yau, Christina; Veer, Laura van T.; Rugo, Hope S.; Pusztai, Lajos; Brown-Swigart, Lamorna; Hirst, Gillian L.; Gallagher, Rosa I.; Delson, Amy L.; Borowsky, Alexander D.; Esserman, Laura J.; Pohlmann, Paula R.; Petricoin, Emanuel F. 分享 收藏
Machine learning elucidates biology of response within and outside the mechanisms of action of therapeutic agents in the I-SPY2 breast cancer TRIAL Sayaman, Rosalyn W.; Wolf, Denise M.; Yau, Christina; Wulfkhule, Julia; Petricoin, Emanuel F.; Brown-Swigart, Lamorna; Bui, Tam Binh; Hirst, Gillian L.; Heditsian, Diane; Symmans, W. Fraser; DeMichele, Angela; LaBarge, Mark; Esserman, Laura J.; van't Veer, Laura 分享 收藏
Subtype-specific signaling dynamics during treatment in non-responding breast cancer patients in the neoadjuvant I-SPY2 TRIAL: are there clues on how to overcome resistance? Wolf, Denise M.; Yau, Christina; Magbanua, Mark Jesus M.; Sayaman, Rosalyn; Wulfkhule, Julia; Gallagher, Rosa I.; Brown-Swigart, Lamorna; Campbell, Michael J.; Basu, Amrita; Hirst, Gillian L.; Perlmutter, Jane; DeMichele, Angela; Yee, Doug; Pusztai, Lajos; Pohlmann, Paula R.; Clark, Amy S.; Rugo, Hope S.; Petricoin, Emanuel F.; Esserman, Laura J.; van't Veer, Laura 分享 收藏
Keratin 17 as a predictor of chemotherapy response in pancreatic ductal adenocarcinoma Oblein, Lyanne; Roa, Lucia; Babu, Sruthi; Horowitz, Michael; Petricoin, Emanuel; Matrisian, Lynn M.; Blais, Edik; Marchenko, Natalia; Allard, Felicia; Alkalin, Ali; Jiang, Wei; Larson, Brent; Hendifar, Andrew; Picozzi, Vincent; Choi, Minsig; Escobar-Hoyos, Luisa; Shroyer, Kenneth 分享 收藏
Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial 蛋白质信号和药物靶标激活特征以指导治疗优先顺序: i-spy 2试验中的治疗抗性和敏感性 Gallagher, Rosa I.; Wulfkuhle, Julia; Wolf, Denise M.; Brown-Swigart, Lamorna; Yau, Christina; O'Grady, Nicholas; Basu, Amrita; Lu, Ruixiao; Campbell, Michael J.; Magbanua, Mark J.; Coppe, Jean-Philippe; Asare, Smita M.; Sit, Laura; Matthews, Jeffrey B.; Perlmutter, Jane; Hylton, Nola; Liu, Minetta C.; Symmans, W. Fraser; Rugo, Hope S.; Isaacs, Claudine; Demichele, Angela M.; Yee, Douglas; Pohlmann, Paula R.; Hirst, Gillian L.; Esserman, Laura J.; van 't Veer, Laura J.; Petricoin, Emanuel F. 分享 收藏
Antibody dependent cell-mediated cytotoxicity selection pressure induces diverse mechanisms of resistance Zahavi, David J.; Erbe, Rossin; Zhang, Yong-Wei; Guo, Theresa; Malchiodi, Zoe X.; Maynard, Rachael; Lekan, Alexander; Gallagher, Rosa; Wulfkuhle, Julia; Petricoin, Emanuel; Jablonski, Sandra A.; Fertig, Elana J.; Weiner, Louis M. 分享 收藏
Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion Damayanti, Nur P.; Saadatzadeh, M. Reza; Dobrota, Erika; Ordaz, Josue D.; Bailey, Barbara J.; Pandya, Pankita H.; Bijangi-Vishehsaraei, Khadijeh; Shannon, Harlan E.; Alfonso, Anthony; Coy, Kathy; Trowbridge, Melissa; Sinn, Anthony L.; Zhang, Zhong-Yin; Gallagher, Rosa I.; Wulfkuhle, Julia; Petricoin, Emanuel; Richardson, Angela M.; Marshall, Mark S.; Lion, Alex; Ferguson, Michael J.; Balsara, Karl E.; Pollok, Karen E. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
