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PLEKHA7 signaling is necessary for the growth of mutant KRAS driven colorectal cancer PLEKHA7信号通路是突变KRAS驱动的结直肠癌生长所必需的 Jeung, Hei-Cheul; Puentes, Roisin; Aleshin, Alexander; Indarte, Martin; Correa, Ricardo G.; Bankston, Laurie A.; Layng, Fabiana I. A. L.; Ahmed, Zamal; Wistuba, Ignacio; Yao, Yong; Duenas, Daniela G.; Zhang, Shuxing; Meuillet, Emmanuelle J.; Marassi, Francesca; Liddington, Robert C.; Kirkpatrick, Lynn; Powis, Garth 分享 收藏
Absence of HIF1A Leads to Glycogen Accumulation and an Inflammatory Response That Enables Pancreatic Tumor Growth Maruggi, Marco; Layng, Fabiana Izidro; Lemos, Robert, Jr.; Garcia, Guillermina; James, Brian P.; Sevilla, Monica; Soldevilla, Ferran; Baaten, Bas J.; de Jong, Petrus R.; Koh, Mei Yee; Powis, Garth 分享 收藏
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors (vol 79, pg 3100, 2019) Indarte, Martin; Puentes, Roisin; Maruggi, Marco; Ihle, Nathan T.; Grandjean, Geoffrey; Scott, Michael; Ahmed, Zamal; Meuillet, Emmanuelle J.; Zhang, Shuxing; Lemos, Robert, Jr.; Du-Cuny, Lei; Layng, Fabiana I. A. L.; Correa, Ricardo G.; Bankston, Laurie A.; Liddington, Robert C.; Kirkpatrick, Lynn; Powis, Garth 分享 收藏
microRNA-211 promotes aggressive melanoma growth in vivo by epigenetic modification, and contributes to BRAFV600E inhibitor resistance via ERK5 signaling Lee, Bongyong; Sahoo, Anupama; Sawada, Junko; Zisoulis, Dimitrios G.; Marchica, John; Sahoo, Sanjay; Layng, Fabiana I. Alves De Lima; Finlay, Darren; Mazar, Joseph; Joshi, Piyush; Komatsu, Masanobu; Vuori, Kristiina; Powis, Garth; de Jong, Petrus R.; Ray, Animesh; Perera, Ranjan J. 分享 收藏
An Inhibitor of the Pleckstrin Homology Domain of CNK1 Selectively Blocks the Growth of Mutant KRAS Cells and Tumors Indarte, Martin; Puentes, Roisin; Maruggi, Marco; Ihle, Nathan T.; Grandjean, Geoffrey; Scott, Michael; Ahmed, Zamal; Meuillet, Emmanuelle J.; Zang, Shuxing; Lemos, Robert, Jr.; Du-Cuny, Lei; Layng, Fabiana I. A. L.; Correa, Ricardo G.; Bankston, Laurie A.; Liddington, Robert C.; Kirkpatrick, Lynn; Powis, Garth 分享 收藏
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Targeting lysophospholipid metabolism inhibits pancreatic cancer cell proliferation under nutrient-limiting conditions de Jong, Petrus R.; Maruggi, Marco; Campos, Alejandro D.; Brand, Morgan A.; Lemos, Robert; Scott, David A.; Litherland, Sally A.; Arnoletti, J. Pablo; James, Brian P.; Powis, Garth 分享 收藏
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Modeling of Patient-Derived Xenografts in Colorectal Cancer Katsiampoura, Anastasia; Raghav, Kanwal; Jiang, Zhi-Qin; Menter, David G.; Varkaris, Andreas; Morelli, Maria P.; Manuel, Shanequa; Wu, Ji; Sorokin, Alexey V.; Rizi, Bahar Salimian; Bristow, Christopher; Tian, Feng; Airhart, Susan; Cheng, Mingshan; Broom, Bradley M.; Morris, Jeffrey; Overman, Michael J.; Powis, Garth; Kopetz, Scott 分享 收藏
Pancreatic cancer cell growth requires lipids released by tumor-induced stroma autophagy De Jong, Petrus R.; Shanahan, Sean-Luc; Brand, Morgan A.; Campos, Alejandro D.; Srirangam, Anagha; Marino, Nikolas; Miller, Claudia P.; Zagnitko, Olga; Richardson, Adam D.; Scott, David A.; James, Brian P.; Hodges, Andrew P.; Perlina, Ally; Eroshin, Alexey M.; French, Randall; Hansen, Malene; Litherland, Sally A.; Lowy, Andrew M.; Arnoletti, J. Pablo; Powis, Garth 分享 收藏
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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target Grandjean, Geoffrey; de Jong, Petrus R.; James, Brian P.; Koh, Mei Yee; Lemos, Robert; Kingston, John; Aleshin, Alexander; Bankston, Laurie A.; Miller, Claudia P.; Cho, Eun Jeong; Edupuganti, Ramakrishna; Devkota, Ashwini; Stancu, Gabriel; Liddington, Robert C.; Dalby, Kevin N.; Powis, Garth 分享 收藏
ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation ERK5信号转导可在ERK1/2废除后挽救肠上皮细胞周转和肿瘤细胞增殖 de Jong, Petrus R.; Taniguchi, Koji; Harris, Alexandra R.; Bertin, Samuel; Takahashi, Naoki; Duong, Jen; Campos, Alejandro D.; Powis, Garth; Corr, Maripat; Karin, Michael; Raz, Eyal 分享 收藏
Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems Chang, Hae Ryung; Park, Hee Seo; Ahin, Young Zoo; Nam, Seungyoon; Jung, Hae Rim; Park, Sungjin; Lee, Sang Jin; Balch, Curt; Powis, Garth; Ku, Ja-Lok; Kim, Yon Hui 分享 收藏
A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice Koh, Mei Yee; Gagea, Mihai; Sargis, Timothy; Lemos, Robert, Jr.; Grandjean, Geoffrey; Charbono, Adriana; Bekiaris, Vasileos; Sedy, John; Kiriakova, Galina; Liu, Xiuping; Roberts, Lewis R.; Ware, Carl; Powis, Garth 分享 收藏
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