Barry S. Cooperman - Publications, H-index & Citations

Barry S. Cooperman

university of pennsylvania

53H指数

323论文数

8.9K被引数

收录论文 86

发表时间

Near-Cognate tRNAs Enhance tRNA Rejection and Prime the Ribosome for Rapid Subsequent tRNA Testing 近同源tRNAs增强tRNA排斥并预置核糖体以进行快速后续tRNA测试

Biophysical Journal

IF3.1

2025-10-10

PREAI

Clark Fritsch; Arpan Bhattacharya; Martin Y. Ng; Hong Li; Philip C. Nelson; Barry S. Cooperman; Yale E. Goldman

Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases 基于机制的方法在针对无义突变疾病设计患者特异性联合疗法中的应用

NUCLEIC ACIDS RESEARCH

IF13.1

2025-03-29

OAAI

Bhat, Saleem Y.; Bhattacharya, Arpan; Li, Hong; Cui, Xiaonan; Lueck, John D.; Goldman, Yale E.; Cooperman, Barry S.

Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria 哺乳动物线粒体中无前导和多顺反子转录本的翻译启动

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-11

OAAI

Remes, Cristina; Khawaja, Anas; Pearce, Sarah F.; Dinan, Adam M.; Gopalakrishna, Shreekara; Cipullo, Miriam; Kyriakidis, Vasileios; Zhang, Jingdian; Dopico, Xaquin Castro; Yukhnovets, Olessya; Atanassov, Ilian; Firth, Andrew E.; Cooperman, Barry; Rorbach, Joanna

Human mitochondria require mtRF1 for translation termination at non-canonical stop codons 人类线粒体需要mtRF1在非规范终止密码子处进行翻译终止

NATURE COMMUNICATIONS

IF15.7

2023-01-03

OAAI

Kruger, Annika; Remes, Cristina; Shiriaev, Dmitrii Igorevich; Liu, Yong; Spahr, Henrik; Wibom, Rolf; Atanassov, Ilian; Nguyen, Minh Duc; Cooperman, Barry S.; Rorbach, Joanna

Ataluren binds to multiple protein synthesis apparatus sites and competitively inhibits release factor-dependent termination

NATURE COMMUNICATIONS

IF15.7

2022-05-06

OAAI

Huang, Shijie; Bhattacharya, Arpan; Ghelfi, Mikel D.; Li, Hong; Fritsch, Clark; Chenoweth, David M.; Goldman, Yale E.; Cooperman, Barry S.

Site-Specific Fluorescent Labeling of RNA Interior Positions RNA内部位置的位点特异性荧光标记

MOLECULES

IF4.6

2021-03-03

OAAI

Cooperman, Barry S.

Ataluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-01-07

OAAI

Ng, Martin Y.; Li, Hong; Ghelfi, Mikel D.; Goldman, Yale E.; Cooperman, Barry S.

Dynamics of intracellular stress-induced tRNA trafficking

NUCLEIC ACIDS RESEARCH

IF13.1

2018-11-28

OAAI

Dhaka, Rabin; Tong, Chunyi; Anderson, Sean; Kashina, Anna S.; Cooperman, Barry; Bau, Haim H.

New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2018-11-21

OAAI

Ng, Martin Y.; Zhang, Haibo; Weil, Amy; Singh, Vijay; Jamiolkowski, Ryan; Baradaran-Heravi, Alireza; Roberge, Michel; Jacobson, Allan; Friesen, Westley; Welch, Ellen; Goldman, Yale E.; Cooperman, Barry S.

Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome

NUCLEIC ACIDS RESEARCH

IF13.1

2018-08-11

OAAI

Kavaliauskas, Darius; Chen, Chunlai; Liu, Wei; Cooperman, Barry S.; Goldman, Yale E.; Knudsen, Charlotte R.

E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form 与GTP类似物结合的大肠杆菌延伸因子Tu显示出与GDP结合形式等效的开放构象

NUCLEIC ACIDS RESEARCH

IF13.1

2018-08-11

OAAI

Johansen, Jesper S.; Kavaliauskas, Darius; Pfeil, Shawn H.; Blaise, Mickael; Cooperman, Barry S.; Goldman, Yale E.; Thirup, Soren S.; Knudsen, Charlotte R.

Translocation kinetics and structural dynamics of ribosomes are modulated by the conformational plasticity of downstream pseudoknots

NUCLEIC ACIDS RESEARCH

IF13.1

2018-07-16

OAAI

Wu, Bo; Zhang, Haibo; Sun, Ruirui; Peng, Sijia; Cooperman, Barry S.; Goldman, Yale E.; Chen, Chunlai

tRNA Fluctuations Observed on Stalled Ribosomes Are Suppressed during Ongoing Protein Synthesis

BIOPHYSICAL JOURNAL

IF3.1

2017-12-01

OAAI

Jamiolkowski, Ryan M.; Chen, Chunlai; Cooperman, Barry S.; Goldman, Yale E.

Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position

MOLECULES

IF4.6

2017-08-29

OAAI

Liu, Wei; Shin, Dongwon; Ng, Martin; Sanbonmatsu, Karissa Y.; Tor, Yitzhak; Cooperman, Barry S.

The kinetic mechanism of bacterial ribosome recycling

NUCLEIC ACIDS RESEARCH

IF13.1

2017-08-02

OAAI

Chen, Yuanwei; Kaji, Akira; Kaji, Hideko; Cooperman, Barry S.

In vivo single-RNA tracking shows that most tRNA diffuses freely in live bacteria

NUCLEIC ACIDS RESEARCH

IF13.1

2016-09-12

OAAI

Plochowietz, Anne; Farrell, Ian; Smilansky, Zeev; Cooperman, Barry S.; Kapanidis, Achillefs N.

Elongation factor G initiates translocation through a power stroke 伸长因子G通过动力冲程启动易位

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-06-16

OAAI

Chen, Chunlai; Cui, Xiaonan; Beausang, John F.; Zhang, Haibo; Farrell, Ian; Cooperman, Barry S.; Goldman, Yale E.

Kinetics of initiating polypeptide elongation in an IRES-dependent system

ELIFE

IF0

2016-06-02

OAAI

Zhang, Haibo; Ng, Martin Y.; Chen, Yuanwei; Cooperman, Barry S.

Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-02-26

OAAI

Glassford, Ian; Teijaro, Christiana N.; Daher, Samer S.; Weil, Amy; Small, Meagan C.; Redhu, Shiv K.; Colussi, Dennis J.; Jacobson, Marlene A.; Childers, Wayne E.; Buttaro, Bettina; Nicholson, Allen W.; MacKerell, Alexander D., Jr.; Cooperman, Barry S.; Andrade, Rodrigo B.

Electrophoretic Deformation of Individual Transfer RNA Molecules Reveals Their Identity

NANO LETTERS

IF9.1

2015-12-02

OAAI

Henley, Robert Y.; Ashcroft, Brian Alan; Farrell, Ian; Cooperman, Barry S.; Lindsay, Stuart M.; Wanunu, Meni

研究方向