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The Triple Alliance: Microbiome, Mitochondria, and Metabolites in the Context of Age-Related Cognitive Decline and Alzheimer's Disease 三重联盟: 年龄相关的认知下降和阿尔茨海默病背景下的微生物,线粒体和代谢物 Prajapati, Santosh K.; Shah, Ria; Alford, Nicholas; Mishra, Sidharth P.; Jain, Shalini; Hansen, Barbara; Sanberg, Paul; Molina, Anthony J. A.; Yadav, Hariom 分享 收藏
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Diabetic Nephropathy in Spantaneously Type 2 Diabetic Nonthuman Primates (Rhesus Monkeys Macaca Mulatta): Comparatory validation of Angiotensin Receptor Blocker Valsartan Hansen, Barbara; Yang, Zunyuan; Liang, Yinan; Yao, Zunwei; Zeng, Licai; Wu, Mingling; Yang, Zhenyan; Gong, Li; Sun, Fengjiao; Newcomb, Jennifer; Zeng, Wen 分享 收藏
Atypical PKC controls β-secretase expression and thereby regulates production of Alzheimer plaque precursor Aβ in brain and insulin receptor degradation in liver 非典型PKC控制 β-分泌酶的表达,从而调节大脑中阿尔茨海默氏斑块前体a β 的产生和肝脏中胰岛素受体的降解 Sajan, Mini P.; Braun, Ursula; Leitges, Michael; Park, Colin; Diamond, David M.; Wu, Jin; Hansen, Barbara C.; Duncan, Mildred Acevedo; Apostolatos, Christopher A.; Apostolatos, Andre H.; Kindy, Mark; Farese, Robert V. 分享 收藏
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Altered expression of p63 isoforms and expansion of p63-and club cell secretory protein-positive epithelial cells in the lung as novel features of aging Fukumoto, Jutaro; Patil, Sahehgowda Sidramagowda; Krishnamurthy, Sudarshan; Saji, Smita; John, Irene; Narala, Venkata Ramireddy; Hernandez-Cuervo, Helena; Alleyn, Matthew; Breitzig, Mason T.; Galam, Lakshmi; Soundararajan, Ramani; Chaudhari, Uddhav K.; Hansen, Barbara C.; Lockey, Richard F.; Kolliputi, Narasaiah 分享 收藏
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Atypical PKC, PKC λ/t, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease 非典型PKC,PKC λ/t,激活 β-分泌酶并增加小鼠大脑和分离的神经元细胞中的Aβ1-40/42和磷酸化tau,并且可能将高胰岛素血症和其他aPKC激活剂与阿尔茨海默氏病的病理和记忆异常的发展联系起来病 Sajan, Mini P.; Hansen, Barbara C.; Higgs, Margaret G.; Kahn, C. Ron; Braun, Ursula; Leitges, Michael; Park, Collin R.; Diamond, David M.; Farese, Robert V. 分享 收藏
Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials Hansen, Barbara C.; Gografe, Sylvia; Pritt, Stacy; Jen, Kai-lin Catherine; McWhirter, Camille A.; Barman, Susan M.; Comuzzie, Anthony; Greene, Molly; McNulty, Justin A.; Michele, Daniel Eugene; Moaddab, Naz; Nelson, Randall J.; Norris, Karen; Uray, Karen D.; Banks, Ron; Westlund, Karin N.; Yates, Bill J.; Silverman, Jerald; Hansen, Kenneth D.; Redman, Barbara 分享 收藏
Increased vimentin in human α- and β-cells in type 2 diabetes Roefs, Maaike M.; Carlotti, Francoise; Jones, Katherine; Wills, Hannah; Hamilton, Alexander; Verschoor, Michael; Durkin, Joanna M. Williams; Garcia-Perez, Laura; Brereton, Melissa F.; McCulloch, Laura; Engelse, Marten A.; Johnson, Paul R. V.; Hansen, Barbara C.; Docherty, Kevin; de Koning, Eelco J. P.; Clark, Anne 分享 收藏
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Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus Luca, Giovanni; Arato, Iva; Mancuso, Francesca; Calvitti, Mario; Falabella, Giulia; Murdolo, Giuseppe; Basta, Giuseppe; Cameron, Don F.; Hansen, Barbara C.; Fallarino, Francesca; Baroni, Tiziano; Aglietti, Maria Chiara; Tortoioli, Cristina; Bodo, Maria; Calafiore, Riccardo 分享 收藏
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Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer Development Sajan, Mini; Hansen, Barbara; Ivey, Robert, III; Sajan, Joshua; Ari, Csilla; Song, Shijie; Braun, Ursula; Leitges, Michael; Farese-Higgs, Margaret; Farese, Robert V. 分享 收藏