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J

John M. Denu

University of Wisconsin System

86H指数
314论文数
3.0W被引数
收录论文 144
发表时间
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HISTONE-MODIFYING ENZYMES IN ANDROGEN-DEPRIVED PROSTATE CANCER: EZH1 AS A SYNERGISTIC THERAPEUTIC TARGET组蛋白修饰酶在去势抵抗性前列腺癌中的作用：EZH1作为协同治疗靶点
errJournal of Urology
IF6.8
err2026-05-01
err0
PREAI
errPurohit, Tanaya A.; Schmitt, Emily; Schultz, Zachary; Bigarella, Marcelo; Bahr, Kayla; Rhizvi, Mohammad; Garcia, Diana; Heninger, Erika; Lang, Josh; Esbona, Karla; Huang, Wei; Lewis, Peter W.; Denu, John M.; Yang, Bing; Jarrard, David F.
err分享
err收藏
EPIGENETIC BIOMARKERS PREDICT RESPONSE TO ANDROGEN DEPRIVATION AND IDENTIFY NOVEL THERAPEUTIC TARGETS IN PROSTATE CANCER表观遗传生物标志物预测前列腺癌对雄激素剥夺治疗的反应并鉴定新型治疗靶点
errJournal of Urology
IF6.8
err2026-05-01
err0
PREAI
errRoadman, Daniel F.; Schmitt, Emily; Purohit, Tanaya A.; Schultz, Zachary; Bigarella, Marcelo; Rhizvi, Mohammad; Lang, Joshua; Huang, Wei; Lewis, Peter W.; Denu, John M.; Yang, Bing; Allen, Glenn O.; Lotan, Paz; Abel, E. Jason; Richards, Kyle A.; Risk, Michael C.; Shapiro, Daniel D.; Koehne, Elizabeth; Jarrard, David F.
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Depletion of individual dietary amino acids induce distinct metabolic and chromatin states单一膳食氨基酸耗竭诱导独特的代谢和染色质状态
errJournal of Biological Chemistry
IF3.9
err2026-01-01
err0
errOAAI
errHaws, Spencer A.; Liu, Yang; Green, Cara L.; Chaiyakul, Krittisak; Mishra, Pragyan; Babygirija, Reji; Armstrong, Eric A.; Mehendale, Anusha T.; Ong, Irene M.; Lamming, Dudley W.; Denu, John M.
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err收藏
A needed nomenclature for nucleosomes核小体所需的命名法
errMolecular Cell
IF16.6
err2025-10-02
err0
PREAI
errMichael-Christopher Keogh; Genevieve Almouzni; Andrew J. Andrews; Karim-Jean Armache; Cheryl H. Arrowsmith; Sung Hee Baek; Mark T. Bedford; Emily Bernstein; Jacques Côté; Yael David; John M. Denu; Beat Fierz; Benjamin A. Garcia; Karen C. Glass; Or Gozani; Kristian Helin; Steven Henikoff; Ole N. Jensen; Steven Z. Josefowicz; Neil L. Kelleher; Tatiana G. Kutateladze; Herbert H. Lindner; Chao Lu; Karolin Luger; Parag Mallick; Catherine A. Musselman; Tom W. Muir; Ljiljana Paša-Tolić; Robert Schneider; Xiaobing Shi; Yang Shi; Simone Sidoli; Lloyd M. Smith; Jessica K. Tyler; Cynthia Wolberger; Jerry L. Workman; Brian D. Strahl; Nicolas L. Young
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err收藏
Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease禁食对于 calorie restriction 在 3xTg 阿尔茨海默病小鼠模型中的许多益处是必需的。
errNature Communications
IF15.7
err2025-08-04
err0
errOAAI
errReji Babygirija; Jessica H. Han; Michelle M. Sonsalla; Ryan Matoska; Mariah F. Calubag; Cara L. Green; Anna Tobon; Chung-Yang Yeh; Diana Vertein; Sophia Schlorf; Julia Illiano; Yang Liu; Isaac Grunow; Michael J. Rigby; Luigi Puglielli; David A. Harris; John M. Denu; Dudley W. Lamming
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err收藏
Gut microbiota-derived metabolite Trimethylamine N-oxide alters the host epigenome through inhibition of S-adenosylhomocysteine hydrolase肠道微生物衍生的代谢物Trimethylamine N-oxide通过抑制S-adenosylhomocysteine hydrolase来改变宿主表观基因组
errJournal of Biological Chemistry
IF3.9
err2025-07-25
err0
errOAAI
errJessica H. Han; Federico E. Rey; John M. Denu
err分享
err收藏
H2A.Z deposition by the SWR complex is stimulated by polyadenine DNA sequences in nucleosomesSWR复合体介导的H2A.Z组蛋白沉积可被核小体中的聚腺嘌呤DNA序列刺激。
errPLOS BIOLOGY
IF7.2
err2025-05-12
err1
errOAAI
errConverso, Cynthia; Pierrakeas, Leonidas; Chan, Lirong; Chowdhury, Shalvi; de Onis, Emily; Kuznetsov, Vyacheslav I.; Denu, John M.; Luk, Ed
err分享
err收藏
The role of ATP citrate lyase in myelin formation and maintenance
errGLIA
IF5.1
err2024-09-25
err0
errOAAI
errSchneider, Andrew; Won, Seongsik; Armstrong, Eric A.; Cooper, Aaron J.; Suresh, Amulya; Rivera, Rachell; Barrett-Wilt, Gregory; Denu, John M.; Simcox, Judith A.; Svaren, John
err分享
err收藏
Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease
errNATURE COMMUNICATIONS
IF15.7
err2024-06-18
err3
errOAAI
errBabygirija, Reji; Sonsalla, Michelle M.; Mill, Jericha; James, Isabella; Han, Jessica H.; Green, Cara L.; Calubag, Mariah F.; Wade, Gina; Tobon, Anna; Michael, John; Trautman, Michaela M.; Matoska, Ryan; Yeh, Chung-Yang; Grunow, Isaac; Pak, Heidi H.; Rigby, Michael J.; Baldwin, Dominique A.; Niemi, Natalie M.; Denu, John M.; Puglielli, Luigi; Simcox, Judith; Lamming, Dudley W.
err分享
err收藏
DOT1L is a barrier to histone acetylation during reprogramming to pluripotency
errSCIENCE ADVANCES
IF12.5
err2023-11-17
err3
errOAAI
errWille, Coral K.; Zhang, Xiaoya; Haws, Spencer A.; Denu, John M.; Sridharan, Rupa
err分享
err收藏
Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7寡核苷酸激活的Sirtuin 7的底物和环肽抑制剂
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-11-07
err5
errOAAI
errBolding, Julie E.; Nielsen, Alexander L.; Jensen, Iben; Hansen, Tobias N.; Ryberg, Line A.; Jameson, Samuel T.; Harris, Pernille; Peters, Guenther H. J.; Denu, John M.; Rogers, Joseph M.; Olsen, Christian A.
err分享
err收藏
The citrate transporters SLC13A5 and SLC25A1 elicit different metabolic responses and phenotypes in the mouse
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-09-09
err5
errOAAI
errFernandez-Fuente, Gonzalo; Overmyer, Katherine A.; Lawton, Alexis J.; Kasza, Ildiko; Shapiro, Samantha L.; Gallego-Munoz, Patricia; Coon, Joshua J.; Denu, John M.; Alexander, Caroline M.; Puglielli, Luigi
err分享
err收藏
Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-adenosylmethionine
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-07-01
err4
errOAAI
errHaws, Spencer A.; Miller, Lillian J.; La Luz, Diego Rojas; Kuznetsov, Vyacheslav I.; Trievel, Raymond C.; Craciun, Gheorghe; Denu, John M.
err分享
err收藏
Genetic alterations induce distinct histone post-translational modifications during the transition to castration-resistant prostate cancer
errCANCER RESEARCH
IF16.6
err2023-06-02
err0
PREAI
errPurohit, Tanaya A.; Gawdzik, Joseph; Yang, Bing; Armstrong, Eric A.; Lewis, Peter W.; Denu, John M.; Jarrard, David F.
err分享
err收藏
Alterations in SIRT2H3K18Ac identify increased P300 activity in circulating tumor cells from patients with CRPC
errCANCER RESEARCH
IF16.6
err2023-06-02
err1
PREAI
errFilon, Mikolaj; Yang, Bing; Schehr, Jennifer; Singh, Anupama; Bigarella, Marcelo; Denu, John; Lang, Joshua; Jarrard, David
err分享
err收藏
The acetyltransferase activity of CBP is required for wingless activation and H4 acetylation in Drosophila melanogaster
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err55
errOAAI
errLudlam, WH; Taylor, MH; Tanner, KG; Denu, JM; Goodman, RH; Smolik, SM
err分享
err收藏
Trimethylamine N-Oxide Reduces Neurite Density and Plaque Intensity in a Murine Model of Alzheimer's Disease
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2022-11-08
err13
errOAAI
errZarbock, Katie R.; Han, Jessica H.; Singh, Ajay P.; Thomas, Sydney P.; Bendlin, Barbara B.; Denu, John M.; Yu, John-Paul J.; Rey, Federico E.; Ulland, Tyler K.
err分享
err收藏
SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction
errAGING CELL
IF7.1
err2022-10-05
err14
errOAAI
errDhillon, Rashpal S.; Qin, Yiming (Amy); van Ginkel, Paul R.; Fu, Vivian X.; Vann, James M.; Lawton, Alexis J.; Green, Cara L.; Manchado-Gobatto, Fulvia B.; Gobatto, Claudio A.; Lamming, Dudley W.; Prolla, Tomas A.; Denu, John M.
err分享
err收藏
Potent Activation of NAD+-Dependent Deacetylase Sirt7 by Nucleosome Binding
errACS CHEMICAL BIOLOGY
IF3.8
err2022-08-08
err8
errOAAI
errKuznetsov, Vyacheslav I.; Liu, Wallace H.; Klein, Mark A.; Denu, John M.
err分享
err收藏
Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology
errBRAIN
IF11.7
err2022-02-25
err14
errOAAI
errRigby, Michael J.; Orefice, Nicola Salvatore; Lawton, Alexis J.; Ma, Min; Shapiro, Samantha L.; Yi, Sue Y.; Dieterich, Inca A.; Frelka, Alyssa; Miles, Hannah N.; Pearce, Robert A.; Yu, John Paul J.; Li, Lingjun; Denu, John M.; Puglielli, Luigi
err分享
err收藏

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