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Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype 单细胞多组学分析揭示具有复杂核型的急性髓系白血病的动态克隆进化和可靶向表型 Leppae, Aino-Maija; Grimes, Karen; Jeong, Hyobin; Huang, Frank Y.; Andrades, Alvaro; Waclawiczek, Alexander; Boch, Tobias; Jauch, Anna; Renders, Simon; Stelmach, Patrick; Mueller-Tidow, Carsten; Karpova, Darja; Sohn, Markus; Gruenschlaeger, Florian; Hasenfeld, Patrick; Benito Garagorri, Eva; Thiel, Vera; Dolnik, Anna; Rodriguez-Martin, Bernardo; Bullinger, Lars; Mrozek, Krzysztof; Eisfeld, Ann-Kathrin; Kraemer, Alwin; Sanders, Ashley D.; Korbel, Jan O.; Trumpp, Andreas 分享 收藏
Bortezomib before and after high-dose therapy in transplant-eligible patients with newly diagnosed multiple myeloma: Long-term overall survival after more than 10 years of follow-up from the phase III HOVON-65/GMMG-HD4 trial Mai, Elias K.; Nogai, Axel; Lokhorst, Henk M.; van der Holt, Bronno; Zweegman, Sonja; Weisel, Katja C.; Croockewit, Sandra; Jauch, Anna; Hillengass, Jens; Stevens-Kroef, Marian; Raab, Marc S.; Broijl, Annemiek; Bos, Gerard M. J.; Brossart, Peter; Ypma, Paula; Hanoun, Christine; Bertsch, Uta; Hielscher, Thomas; Salwender, Hans J.; Scheid, Christoph; Goldschmidt, Hartmut; Sonneveld, Pieter 分享 收藏
Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress de Jaime-Soguero, Anchel; Hattemer, Janina; Bufe, Anja; Haas, Alexander; van den Berg, Jeroen; van Batenburg, Vincent; Das, Biswajit; di Marco, Barbara; Androulaki, Stefania; Boehly, Nicolas; Landry, Jonathan J. M.; Schoell, Brigitte; Rosa, Viviane S.; Villacorta, Laura; Baskan, Yagmur; Trapp, Marleen; Benes, Vladimir; Chabes, Andrei; Shahbazi, Marta; Jauch, Anna; Engel, Ulrike; Patrizi, Annarita; Sotillo, Rocio; van Oudenaarden, Alexander; Bageritz, Josephine; Alfonso, Julieta; Bastians, Holger; Acebron, Sergio P. 分享 收藏
CD8+ CD28- regulatory T cells after induction therapy predict progression-free survival in myeloma patients: results from the GMMG-HD6 multicenter phase III study Kriegsmann, Katharina; Ton, Gigi Nu Hoang Quy; Awwad, Mohamed H. S.; Benner, Axel; Bertsch, Uta; Besemer, Britta; Haenel, Mathias; Fenk, Roland; Munder, Markus; Duerig, Jan; Blau, Igor W.; Huhn, Stefanie; Hose, Dirk; Jauch, Anna; Mann, Christoph; Weinhold, Niels; Scheid, Christof; Schroers, Roland; von Metzler, Ivana; Schieferdecker, Aneta; Thomalla, Joerg; Reimer, Peter; Mahlberg, Rolf; Graeven, Ullrich; Kremers, Stephan; Martens, Uwe M.; Kunz, Christian; Hensel, Manfred; Seidel-Glaetzer, Andrea; Weisel, Katja C.; Salwender, Hans J.; Mueller-Tidow, Carsten; Raab, Marc S.; Goldschmidt, Hartmut; Mai, Elias K.; Hundemer, Michael 分享 收藏
Artificial intelligence-based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma [18F]FDG PET/CT中基于人工智能的骨髓代谢活动容量评估可预测多发性骨髓瘤的生存 Sachpekidis, Christos; Enqvist, Olof; Ulen, Johannes; Kopp-Schneider, Annette; Pan, Leyun; Mai, Elias K.; Hajiyianni, Marina; Merz, Maximilian; Raab, Marc S.; Jauch, Anna; Goldschmidt, Hartmut; Edenbrandt, Lars; Dimitrakopoulou-Strauss, Antonia 分享 收藏
Chromosome 8p engineering reveals increased metastatic potential targetable by patient-specific synthetic lethality in liver cancer Huth, Thorben; Dreher, Emely C.; Lemke, Steffen; Fritzsche, Sarah; Sugiyanto, Raisatun N.; Castven, Darko; Ibberson, David; Sticht, Carsten; Eiteneuer, Eva; Jauch, Anna; Pusch, Stefan; Albrecht, Thomas; Goeppert, Benjamin; Candia, Julian; Wang, Xin Wei; Ji, Junfang; Marquardt, Jens U.; Nahnsen, Sven; Schirmacher, Peter; Roessler, Stephanie 分享 收藏
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma Emde-Rajaratnam, Martina; Beck, Susanne; Benes, Vladimir; Salwender, Hans; Bertsch, Uta; Scheid, Christoph; Haenel, Mathias; Weisel, Katja; Hielscher, Thomas; Raab, Marc S.; Goldschmidt, Hartmut; Jauch, Anna; Maes, Ken; De Bruyne, Elke; Menu, Eline; De Veirman, Kim; Moreaux, Jerome; Vanderkerken, Karin; Seckinger, Anja; Hose, Dirk 分享 收藏
Application of an artificial intelligence-based tool in [18F]FDG PET/CT for the assessment of bone marrow involvement in multiple myeloma 基于人工智能的工具在[18F]FDG PET/CT中的应用：用于评估多发性骨髓瘤的骨髓受累情况 Sachpekidis, Christos; Enqvist, Olof; Ulen, Johannes; Kopp-Schneider, Annette; Pan, Leyun; Jauch, Anna; Hajiyianni, Marina; John, Lukas; Weinhold, Niels; Sauer, Sandra; Goldschmidt, Hartmut; Edenbrandt, Lars; Dimitrakopoulou-Strauss, Antonia 分享 收藏
Prediction of Bone Marrow Biopsy Results From MRI in Multiple Myeloma Patients Using Deep Learning and Radiomics 使用深度学习和放射组学预测多发性骨髓瘤患者MRI的骨髓活检结果 Wennmann, Markus; Ming, Wenlong; Bauer, Fabian; Chmelik, Jiri; Klein, Andre; Uhlenbrock, Charlotte; Groezinger, Martin; Kahl, Kim-Celine; Nonnenmacher, Tobias; Debic, Manuel; Hielscher, Thomas; Thierjung, Heidi; Rotkopf, Lukas T.; Stanczyk, Nikolas; Sauer, Sandra; Jauch, Anna; Goetz, Michael; Kurz, Felix T.; Schlamp, Kai; Horger, Marius; Afat, Saif; Besemer, Britta; Hoffmann, Martin; Hoffend, Johannes; Kraemer, Doris; Graeven, Ullrich; Ringelstein, Adrian; Bonekamp, David; Kleesiek, Jens; Floca, Ralf O.; Hillengass, Jens; Mai, Elias K.; Weinhold, Niels; Weber, Tim F.; Goldschmidt, Hartmut; Schlemmer, Heinz-Peter; Maier-Hein, Klaus; Delorme, Stefan; Neher, Peter 分享 收藏
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia Beneyto-Calabuig, Sergi; Merbach, Anne Kathrin; Kniffka, Jonas-Alexander; Antes, Magdalena; Szu-Tu, Chelsea; Rohde, Christian; Waclawiczek, Alexander; Stelmach, Patrick; Graessle, Sarah; Pervan, Philip; Janssen, Maike; Landry, Jonathan J. M.; Benes, Vladimir; Jauch, Anna; Brough, Michaela; Bauer, Marcus; Besenbeck, Birgit; Felden, Julia; Baeumer, Sebastian; Hundemer, Michael; Sauer, Tim; Pabst, Caroline; Wickenhauser, Claudia; Angenendt, Linus; Schliemann, Christoph; Trumpp, Andreas; Haas, Simon; Scherer, Michael; Raffel, Simon; Mueller-Tidow, Carsten; Velten, Lars 分享 收藏
Sourcing high tissue quality brains from deceased wild primates with known socio-ecology Graessle, Tobias; Crockford, Catherine; Eichner, Cornelius; Girard-Buttoz, Cedric; Jaeger, Carsten; Kirilina, Evgeniya; Lipp, Ilona; Duex, Ariane; Edwards, Luke; Jauch, Anna; Kopp, Kathrin S. S.; Paquette, Michael; Pine, Kerrin; Haun, Daniel B. M.; McElreath, Richard; Anwander, Alfred; Gunz, Philipp; Morawski, Markus D.; Friederici, Angela D.; Weiskopf, Nikolaus H.; Leendertz, Fabian H. M.; Wittig, Roman M. 分享 收藏
Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma 质谱对新诊断多发性骨髓瘤患者的意义和预后影响 Mai, Elias K.; Huhn, Stefanie; Miah, Kaya; Poos, Alexandra M.; Scheid, Christof; Weisel, Katja C.; Bertsch, Uta; Munder, Markus; Berlanga, Oscar; Hose, Dirk; Seckinger, Anja; Jauch, Anna; Blau, Igor W.; Haenel, Mathias; Salwender, Hans J.; Benner, Axel; Raab, Marc S.; Goldschmidt, Hartmut; Weinhold, Niels 分享 收藏
Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis Jauch, Anna Sophia; Wohlfeil, Sebastian A.; Weller, Celine; Dietsch, Bianca; Haefele, Verena; Stojanovic, Ana; Kittel, Maximilian; Nolte, Hendrik; Cerwenka, Adelheid; Neumaier, Michael; Schledzewski, Kai; Sticht, Carsten; Reiners-Koch, Philipp-Sebastian; Goerdt, Sergij; Geraud, Cyrill 分享 收藏
Deep Learning for Automatic Bone Marrow Apparent Diffusion Coefficient Measurements From Whole-Body Magnetic Resonance Imaging in Patients With Multiple Myeloma A Retrospective Multicenter Study Wennmann, Markus; Neher, Peter; Stanczyk, Nikolas; Kahl, Kim-Celine; Kaechele, Jessica; Weru, Vivienn; Hielscher, Thomas; Groezinger, Martin; Chmelik, Jiri; Zhang, Kevin Sun; Bauer, Fabian; Nonnenmacher, Tobias; Debic, Manuel; Sauer, Sandra; Rotkopf, Lukas Thomas; Jauch, Anna; Schlamp, Kai; Mai, Elias Karl; Weinhold, Niels; Afat, Saif; Horger, Marius; Goldschmidt, Hartmut; Schlemmer, Heinz-Peter; Weber, Tim Frederik; Delorme, Stefan; Kurz, Felix Tobias; Maier-Hein, Klaus 分享 收藏
Atypical presentation of patients with chronic myeloid leukemia in chronic phase-Case report Ramdohr, Florian; Fabarius, Alice; Maier, Bettina; Bretschneider, Daniela; Jauch, Anna; Monecke, Astrid; Metzeler, Klaus H.; Janssen, Johannes W. G.; Schlenk, Richard F.; Kayser, Sabine 分享 收藏
Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment 血管生成和分子多样性决定肝黑色素瘤转移和对抗血管生成治疗的反应 Wohlfeil, Sebastian A.; Haefele, Verena; Dietsch, Bianca; Weller, Celine; Sticht, Carsten; Jauch, Anna Sophia; Winkler, Manuel; Schmid, Christian David; Irkens, Anna Lena; Olsavszky, Ana; Schledzewski, Kai; Reiners-Koch, Philipp-Sebastian; Goerdt, Sergij; Geraud, Cyrill 分享 收藏
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Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities Giesen, Nicola; Paramasivam, Nagarajan; Toprak, Umut H.; Huebschmann, Daniel; Xu, Jing; Uhrig, Sebastian; Samur, Mehmet; Baehr, Stella; Froehlich, Martina; Mughal, Sadaf S.; Mai, Elias K.; Jauch, Anna; Muller-Tidow, Carsten; Brors, Benedikt; Munshi, Nikhil; Goldschmidt, Hartmut; Weinhold, Niels; Schlesner, Matthias; Raab, Marc S. 分享 收藏
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