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Comparison of single agent versus combination activity of enfortumab vedotin (EV) and sacituzumab govitecan (SG) in a panel of bladder cancer XPDX models Simonson, A.; Flores, J.; Mercer, G.; Lopez, M.; Garcia, R.; Lund, J.; Banos, N.; Papadopoulos, K.; Calvo, E.; Pedregal, M.; Hernandez, T.; Rasco, D.; Patnaik, A.; Garcia-Foncillas, J.; Wick, M. 分享 收藏
Activity of alpelisib in a panel of breast XPDX models harboring hotspot and uncommon PIK3CA mutations Castaneda, Mercedes; Simonson, Alyssa; Flores, Johnnie; DeBoer, Maci; Lund, Jim; Rouzbahan, Tahmi; Papadopoulos, Kyriakos P.; Lang, Amy; Rodriguez, Gladys; Elmi, Maryam; Rosenthal, Arthur; Rasco, Drew; Moreno, Victor; Patnaik, Amita; Hernandez, Tatiana; Calvo, Emiliano; Smith, Lon; Sharma, Manish; Beeram, Muralidhar; Wick, Michael 分享 收藏
KB-0742, an oral highly selective CDK9 inhibitor, demonstrates preclinical activity in transcription factor fusion driven adenoid cystic carcinoma patient-derived models McKeown, Michael R.; Carvajal, Luis A.; Hood, Tressa R.; Burr, Nicole S.; Kaufman, Jeffrey; Boynton, Adam; Mori, Kameron; DesRochers, Tessa; Wick, Michael; Lin, Charles Y.; DiMartino, Jorge F. 分享 收藏
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Establishment and characterization of a panel of naive and pretreated small cell lung cancer (SCLC) XPDX models Morales, Gabriela Huelgas; Forofontov, Peter; Flores, Johnnie; Simonson, Alyssa; Diaz, Armando, III; Lund, Jim; Banos, Natalia; Papadopoulos, Kyriakos; Rasco, Drew; Patnaik, Amita; Abedi, Ali; Puente, Napoleon; Calvo, Emiliano; Moreno, Victor; Drengler, Ronald; Smith, Lon; Wick, Michael 分享 收藏
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Enfortumab vedotin (EV): Efficacy comparison with trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG) and its potential for combination benefit in bladder cancer XPDX models Flores, Johnnie; Sessions, Heaven; Simonson, Alyssa; Banos, Natalia; Rouzbahani, Tahmineh; Diaz, Armando, III; Lund, Jim; Calvo, Emiliano; Moreno, Victor; Papadopoulos, Kyriakos; Rasco, Drew; Patnaik, Amita; Ulmer, Scott; Rodriguez, Luis; Wick, Michael 分享 收藏
Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma Anti-LGALS3BP抗体-药物缀合物治疗在腺样囊性癌的临床前模型中诱导持久且有效的抗肿瘤反应 Capone, Emily; Perrotti, Vittoria; Cela, Ilaria; Lattanzio, Rossano; Togni, Lucrezia; Rubini, Corrado; Caponio, Vito Carlo Alberto; Lo Muzio, Lorenzo; Colasante, Martina; Giansanti, Francesco; Ippoliti, Rodolfo; Iacobelli, Stefano; Wick, Michael J.; Burr, Nicole Spardy; Sala, Gianluca 分享 收藏
Establishment and characterization of a panel of prostate cancer XPDX models with differential AR-V7 staining and enzalutamide response Lund, Jim; Flores, Johnnie; Simonson, Alyssa; Diaz, Armand, III; Knol, Jared; Kella, Naveen; Rasco, Drew; Papadopoulos, Kyriakos P.; Campbell, Mark; Wick, Michael J. 分享 收藏
Short or long-term treatment with CDK4/6 inhibitors in patients with ER plus breast cancer: characterization and comparative analysis of resistance in seventeen XPDX models Simonson, Alyssa; Flores, Johnnie; Lynch, Morgan; Carpenter, Emily; Hruzek, Justine; Lund, Jim; Herraiz, Natalia Banos; Papadopoulos, Kyriakos; Woude, Amy Vander; Rodriguez, Gladys; Chandana, Sreenivasa; Gribbin, Thomas; Lakhani, Nehal; Hernandez, Tatiana; de Miguel, Maria Jose; Lang, Amy; Wick, Michael J. 分享 收藏
Establishment and characterization of a panel of breast XPDX models representing innate or acquired resistance to trastuzumab deruxtecan (T-DXd) DeBoer, Maci; Paez, Albert; Flores, Johnnie; Baeza, Robyn; Simonson, Alyssa; Lund, Jim; Papadopoulos, Kyriakos; Gribbin, Thomas; Lang, Amy; Rodriguez, Gladys; Mozas, Lorena; Gonzalez, Lorena; Sharma, Manish; Calvo, Emiliano; Hernandez, Tatiana; Wick, Michael J. 分享 收藏
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Correlation of Trop2 expression with in vivo sensitivity to sacituzumab govitecan in a panel of breast XPDX models Simonson, Alyssa; Flores, Johnnie; Anderson, Ebony; Moreno, Crystal; Plasko, George; Papadopoulos, Kyriakos P.; Patnaik, Amita; Rasco, Drew; Rodriguez, Gladys; Lang, Amy; Beeram, Muralidhar; Rodriguez, Luis; Drengler, Ronald; Abbate, Steven; Salih, Hanni; Smith, Lon; Elmi, Maryam; DeBerry, Brittany; Rosenthal, Arthur; Hernandez, Tatiana; Lakhani, Nehal; Sharma, Manish; Wick, Michael 分享 收藏
Establishment and characterization of two ER+/HER2-XPDX models developed sequentially before and after acquired resistance to the CDK4/6 inhibitor palbociclib from a patient with metastatic breast cancer Varma, Ashwin; Flores, Johnnie; Simonson, Alyssa; Stackpole, Anna; Papadopoulos, Kyriakos P.; Patnaik, Amita; Rasco, Drew; Beeram, Muralidhar; Sandera, Marisa; Wick, Michael 分享 收藏
Establishment and characterization of two T-DM1-resistant, ER+/HER2+breast XPDX models developed sequentially from the same patient with differential in vivo sensitivity to trastuzumab deruxtecan (DS-8201a) Plasko, George; Flores, Johnnie; Simonson, Alyssa; Forofontov, Peter; Varma, Ashwin; Lang, Amy; Rodriguez, Gladys; Papadopoulos, Kyriakos P.; Rasco, Drew; Patnaik, Amita; Conway, Bruce; Johnston, Joe; Wick, Michael 分享 收藏
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Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant for Breast Cancer Furman, Craig; Puyang, Xiaoling; Zhang, Zhaojie; Wu, Zhenhua J.; Banka, Deepti; Aithal, Kiran B.; Albacker, Lee A.; Hao, Ming-Hong; Irwin, Sean; Kim, Amy; Montesion, Meagan; Moriarty, Alyssa D.; Murugesan, Karthikeyan; Nguyen, Tuong-Vi; Rimkunas, Victoria; Sahmoud, Tarek; Wick, Michael J.; Yao, Shihua; Zhang, Xun; Zeng, Hao; Vaillancourt, Frederic H.; Bolduc, David M.; Larsen, Nicholas; Zheng, Guo Zhu; Prajapati, Sudeep; Zhu, Ping; Korpal, Manav 分享 收藏
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