未登录IL-7 producing immunotherapy improves ex vivo T cell functions of immunosenescent patients, especially post hip fracture
Marton, Chrystel; Minaud, Alix; Coupet, Charles-Antoine; Chauvin, Manon; Dhiab, Jamila; Vallet, Helene; Boddaert, Jacques; Kehrer, Nadine; Bastien, Berangere; Inchauspe, Genevieve; Barraud, Luc; Sauce, Delphine .png)
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收藏分享 收藏 分享 收藏 Viral Delivery of IL-7 Is a Potent Immunotherapy Stimulating Innate and Adaptive Immunity and Confers Survival in Sepsis ModelsLelu, Karine; Dubois, Clarisse; Evlachev, Alexei; Crausaz, Morgane; Baldazza, Marie; Kehrer, Nadine; Brandely, Renee; Schlesinger, Yasmin; Silvestre, Nathalie; Marchand, Jean-Baptiste; Bastien, Berangere; Leung-Theung-Long, Stephane; Unsinger, Jacqueline; Martin, Perrine; Inchauspe, Genevieve 分享 收藏 Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaquesVierboom, Michel P. M.; Chenine, Agnes L.; Darrah, Patricia A.; Vervenne, Richard A. W.; Boot, Charelle; Hofman, Sam O.; Sombroek, Claudia C.; Dijkman, Karin; Khayum, Mohamed A.; Stammes, Marieke A.; Haanstra, Krista G.; Hoffmann, Chantal; Schmitt, Doris; Silvestre, Nathalie; White, Alexander G.; Borish, H. Jacob; Seder, Robert A.; Quaked, Nadia; Leung-Theung-Long, Stephane; Inchauspe, Genevieve; Anantha, Ravi; Limbach, Mary; Evans, Thomas G.; Casimiro, Danilo; Lempicki, Maria; Laddy, Dominick J.; Bonavia, Aurelio; Verreck, Frank A. W. 分享 收藏 Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial治疗性疫苗TG1050在慢性乙型肝炎患者中的安全性和免疫原性: 1b期安慰剂对照试验Zoulim, Fabien; Fournier, Claire; Habersetzer, Francois; Sprinzl, Martin; Pol, Stanislas; Coffin, Carla S.; Leroy, Vincent; Ma, Mang; Wedemeyer, Heiner; Lohse, Ansgar W.; Thimme, Robert; Lugardon, Karine; Martin, Perrine; Bastien, Berangere; Sansas, Benoit; Adda, Nathalie; Halluard, Celine; Bendjama, Kaidre; Brandely, Maud; Inchauspe, Genevieve 分享 收藏 分享 收藏 Soluble CD163 and their expression on monocytes, constituent potential molecular signature associated with liver inflammation and HBV-specific immune responsesHuang, D.; Sansass, B.; Jiang, J.; Gong, Q.; Wan, M.; Chen, L.; Yang, W.; Jin, G.; Yu, D.; Zhu, M.; Wei, D.; Zhang, D.; Inchauspe, G.; Zhang, X.; Zhu., R. 分享 收藏 TG1050, a novel immunotherapeutic for the treatment of chronic hepatitis B, can control HBsAg and provoke HBsAg seroconversion in HBV-persistent mouse modelsLelu, K.; Evlachev, A.; Kratzer, R.; Godon, O.; Mancini-Bourgine, M.; Dion, S.; Schmitt, D.; Dubois, C.; Meritet, J. F.; Schlesinger, Y.; Marchand, J. B.; Geist, M.; Brandely, R.; Findeli, A.; Zhu, R.; Menguy, T.; Silvestre, N.; Michel, M. L.; Inchauspe, G.; Martin, P. 分享 收藏 TG1050, A NOVEL IMMUNOTHERAPEUTIC TO TREAT CHRONIC HEPATITIS B, CAN CONTROL HBsAg AND PROVOKE HBsAg SEROCONVERSION IN HBV-PERSISTENT MOUSE MODELSLelu, K.; Evlachev, A.; Kratzer, R.; Dion, S.; Mancini-Bourgine, M.; Godon, O.; Schmitt, D.; Dubois, C.; Meritet, J. -F.; Schlesinger, Y.; Marchand, J. -B.; Geist, M.; Brandely, R.; Findeli, A.; Menguy, T.; Silvestre, N.; Michel, M. -L.; Inchauspe, G.; Martin, P. 分享 收藏 分享 收藏 Efficacy of Immunotherapy With TG4040, Peg-Interferon, and Ribavirin in a Phase 2 Study of Patients With Chronic HCV InfectionDi Bisceglie, Adrian M.; Janczweska-Kazek, Ewa; Habersetzer, Franois; Mazur, Wlodzimierz; Stanciu, Carol; Carreno, Vicente; Tanasescu, Coman; Flisiak, Robert; Romero-Gomez, Manuel; Fich, Alexander; Bataille, Vincent; Toh, Myew-Ling; Hennequi, Marie; Zerr, Patricia; Honnet, Geraldine; Inchauspe, Genevieve; Agathon, Delphine; Limacher, Jean-Marc; Wedemeyer, Heiner 分享 收藏 A Heterologous Prime/Boost Vaccination Strategy Enhances the Immunogenicity of Therapeutic Vaccines for Hepatitis C VirusFournillier, Anne; Frelin, Lars; Jacquier, Emilie; Ahlen, Gustaf; Brass, Anette; Gerossier, Estelle; Holmstrom, Fredrik; Broderick, Kate E.; Sardesai, Niranjan Y.; Bonnefoy, Jean-Yves; Inchauspe, Genevieve; Sallberg, Matti 分享 收藏 PHASE II HCVac STUDY OF TG4040 IMMUNOTHERAPEUTIC IN COMBINATION WITH PEGIFNα2a AND RIBAVIRIN IN GENOTYPE 1 CHC TREATMENT NAIVE PATIENTS: SVR24 FINAL RESULTSWedemeyer, H.; Kazek, E. Janczewska; Wlodzimierz, M.; Stanciu, C.; Habersetzer, F.; Carreno, V.; Di Bisceglie, A.; Tanasescu, C.; Flisiak, R.; Romero-Gomez, M.; Fich, A.; Hennequi, M.; Bain, C.; Zerr, P.; Agathon, D.; Adda, N.; Bonnefoy, J. -Y.; Inchauspe, G.; Ancian, P.; Limacher, J. -M. 分享 收藏 A MULTIVALENT ADENOVIRUS-BASED IMMUNOTHERAPEUTIC FOR TREATMENT OF CHRONIC HEPATITIS B INDUCES BROAD, ROBUST AND POLYFUNCTIONAL T CELLS IN NAIVE AND HBV TOLERANT MICEMartin, P.; Dubois, C.; Jacquier, E.; Evlachev, A.; Boukhebza, H.; Dion, S.; Mancini-Bourgine, M.; Godon, O.; Findeli, A.; Schlesinger, Y.; Brandely, R.; Marchand, J-B.; Menguy, T.; Silvestre, N.; Schirmbeck, R.; Michel, M-L.; Inchauspe, G. 分享 收藏 PRE-CLINICAL PROOF-OF-CONCEPT STUDIES EXPLORING SCHEDULES OF ADMINISTRATION OF AN ADENOVIRUS-BASED HBV IMMUNOTHERAPEUTIC SHOW WIDE POTENTIAL FOR INDUCTION OF ROBUST AND LONG-LASTING T-CELL RESPONSESBoukhebza, H.; Dubois, C.; Schlesinger, Y.; Koerper, V.; Brandely, R.; Geist, M.; Menguy, T.; Silvestre, N.; Schirmbeck, R.; Inchauspe, G.; Martin, P. 分享 收藏 TOWARDS THE DEVELOPMENT OF A THERAPEUTIC VACCINE TO TREAT CHRONIC HBV INFECTION: AD5-BASED VACCINES ENCODING MULTIPLE HBV ANTIGENS INDUCE STRONG T-CELL RESPONSES IN PRE-CLINICAL MODELSMartin, P.; Evlachev, A.; Olivier, D.; Beny, C.; Dubois, C.; Findeli, A.; Schlesinger, Y.; Ledoux, C.; Brandely, R.; Menguy, T.; Silvestre, N.; Fournillier, A.; Bonnefoy, J. -Y; Inchauspe, G. 分享 收藏 A Poxvirus Vaccine Is Safe, Induces T-Cell Responses, and Decreases Viral Load in Patients With Chronic Hepatitis CHabersetzer, Francois; Honnet, Geraldine; Bain, Christine; Maynard-Muet, Marianne; Leroy, Vincent; Zarski, Jean-Pierre; Feray, Cyrille; Baumert, Thomas F.; Bronowicki, Jean-Pierre; Doffoel, Michel; Trepo, Christian; Agathon, Delphine; Toh, Myew-Ling; Baudin, Martine; Bonnefoy, Jean-Yves; Limacher, Jean-Marc; Inchauspe, Genevieve 分享 收藏 A NOVEL VECTORIZED HCV THERAPEUTIC VACCINE (TG4040): RESULTS OF A PHASE I STUDY IN NAIVE PATIENTS CHRONICALLY INFECTED BY HCVHabersetzer, F.; Zarski, J-P; Leroy, V.; Maynard-Muet, M.; Bronowicki, J-P; Feray, C.; Hezode, C.; Fournillier, A.; Bain, C.; Inchauspe, G.; Honnet, G.; Trepo, C. 分享 收藏 分享 收藏 
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