Eckard Wimmer - Publications, H-index & Citations

Eckard Wimmer

johson & johnson belgium

96H指数

385论文数

3.4W被引数

收录论文 85

发表时间

Polio eradication at the crossroads

LANCET GLOBAL HEALTH

IF18

2021-08-01

OAAI

Chumakov, Konstantin; Ehrenfeld, Ellie; Agol, Vadim, I; Wimmer, Eckard

Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-06-30

OAAI

Wang, Ying; Yang, Chen; Song, Yutong; Coleman, J. Robert; Stawowczyk, Marcin; Tafrova, Juliana; Tasker, Sybil; Boltz, David; Baker, Robert; Garcia, Liliana; Seale, Olivia; Kushnir, Anna; Wimmer, Eckard; Mueller, Steffen

Rescue of codon-pair deoptimized respiratory syncytial virus by the emergence of genomes with very large internal deletions that complemented replication

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-22

OAAI

Le Nouen, Cyril; McCarty, Thomas; Yang, Lijuan; Brown, Michael; Wimmer, Eckard; Collins, Peter L.; Buchholz, Ursula J.

Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity

JOURNAL OF VIROLOGY

IF3.8

2020-01-06

OAAI

Le Nouen, Cyril; Luongo, Cindy L.; Yang, Lijuan; Mueller, Steffen; Wimmer, Eckard; DiNapoli, Joshua M.; Collins, Peter L.; Buchholz, Ursula J.

Dengue and Zika Virus 5′ Untranslated Regions Harbor Internal Ribosomal Entry Site Functions

MBIO

IF4.7

2019-04-30

OAAI

Song, Yutong; Mugavero, JoAnn; Stauft, Charles B.; Wimmer, Eckard

Limits of variation, specific infectivity, and genome packaging of massively recoded poliovirus genomes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-09-25

OAAI

Song, Yutong; Gorbatsevych, Oleksandr; Liu, Ying; Mugavero, Joann; Shen, Sam H.; Ward, Charles B.; Asare, Emmanuel; Jiang, Ping; Paul, Aniko V.; Mueller, Steffen; Wimmer, Eckard

Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-01-03

OAAI

Le Nouen, Cyril; McCarty, Thomas; Brown, Michael; Smith, Melissa Laird; Lleras, Roberto; Dolan, Michael A.; Mehedi, Masfique; Yang, Lijuan; Luongo, Cindy; Liang, Bo; Munir, Shirin; DiNapoli, Joshua M.; Mueller, Steffen; Wimmer, Eckard; Collins, Peter L.; Buchholz, Ursula J.

A Single Amino Acid Substitution in Poliovirus Nonstructural Protein 2CATPase Causes Conditional Defects in Encapsidation and Uncoating

JOURNAL OF VIROLOGY

IF3.8

2016-07-15

OAAI

Asare, Emmanuel; Mugavero, JoAnn; Jiang, Ping; Wimmer, Eckard; Paul, Aniko V.

Cold-Adapted Viral Attenuation (CAVA): Highly Temperature Sensitive Polioviruses as Novel Vaccine Strains for a Next Generation Inactivated Poliovirus Vaccine

PLOS PATHOGENS

IF4.9

2016-03-31

OAAI

Sanders, Barbara P. d; Oakes, Isabel de los Rios; van Hoek, Vladimir; Bockstal, Viki; Kamphuis, Tobias; Uil, Taco G.; Song, Yutong; Cooper, Gillian; Crawt, Laura E.; Martin, Javier; Zahn, Roland; Lewis, John; Wimmer, Eckard; Custers, Jerome H. H. V.; Schuitemaker, Hanneke; Cello, Jeronimo; Edo-Matas, Diana

Brunenders: a partially attenuated historic poliovirus type I vaccine strain

JOURNAL OF GENERAL VIROLOGY

IF4.3

2015-09-01

OAAI

Sanders, Barbara P.; Liu, Ying; Brandjes, Alies; van Hoek, Vladimir; Oakes, Isabel de los Rios; Lewis, John; Wimmer, Eckard; Custers, Jerome H. H. V.; Schuitemaker, Hanneke; Cello, Jeronimo; Edo-Matas, Diana

Reply to Simmonds et al.: Codon pair and dinucleotide bias have not been functionally distinguished

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-06-12

OAAI

Futcher, Bruce; Gorbatsevych, Oleksandr; Shen, Sam H.; Stauft, Charles B.; Song, Yutong; Wang, Bingyin; Leatherwood, Janet; Gardin, Justin; Yurovsky, Alisa; Mueller, Steffen; Wimmer, Eckard

Recoding of the Vesicular Stomatitis Virus L Gene by Computer-Aided Design Provides a Live, Attenuated Vaccine Candidate

MBIO

IF4.7

2015-05-01

OAAI

Wang, Bingyin; Yang, Chen; Tekes, Gergely; Mueller, Steffen; Paul, Aniko; Whelan, Sean P. J.; Wimmer, Eckard

Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-03-30

OAAI

Shen, Sam H.; Stauft, Charles B.; Gorbatsevych, Oleksandr; Song, Yutong; Ward, Charles B.; Yurovsky, Alisa; Mueller, Steffen; Futcher, Bruce; Wimmer, Eckard

Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-08-25

114

OAAI

Le Nouen, Cyril; Brock, Linda G.; Luongo, Cindy; McCarty, Thomas; Yang, Lijuan; Mehedi, Masfique; Wimmer, Eckard; Mueller, Steffen; Collins, Peter L.; Buchholz, Ursula J.; DiNapoli, Joshua M.

Poliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculation

JOURNAL OF GENERAL VIROLOGY

IF4.3

2014-08-01

OAAI

Khan, Shaukat; Toyoda, Hidemi; Linehan, Melissa; Iwasaki, Akiko; Nomoto, Akio; Bernhardt, Guenter; Cello, Jeronimo; Wimmer, Eckard

A C-terminal, cysteine-rich site in poliovirus 2CATPase is required for morphogenesis

JOURNAL OF GENERAL VIROLOGY

IF4.3

2014-06-01

OAAI

Wang, Chunling; Ma, Hsin-Chieh; Wimmer, Eckard; Jiang, Ping; Paul, Aniko V.

Binding of Glutathione to Enterovirus Capsids Is Essential for Virion Morphogenesis

PLOS PATHOGENS

IF4.9

2014-04-10

OAAI

Thibaut, Hendrik Jan; van der Linden, Lonneke; Jiang, Ping; Thys, Bert; Canela, Maria-Dolores; Aguado, Leire; Rombaut, Bart; Wimmer, Eckard; Paul, Aniko; Perez-Perez, Maria-Jesus; van Kuppeveld, Frank J. M.; Neyts, Johan

An Interaction between Glutathione and the Capsid Is Required for the Morphogenesis of C-Cluster Enteroviruses

PLOS PATHOGENS

IF4.9

2014-04-10

OAAI

Ma, Hsin-Chieh; Liu, Ying; Wang, Chunling; Strauss, Michael; Rehage, Nina; Chen, Ying-Han; Altan-Bonnet, Nihal; Hogle, James; Wimmer, Eckard; Mueller, Steffen; Paul, Aniko V.; Jiang, Ping

Deliberate reduction of hemagglutinin and neuraminidase expression of influenza virus leads to an ultraprotective live vaccine in mice

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-05-20

111

OAAI

Yang, Chen; Skiena, Steven; Futcher, Bruce; Mueller, Steffen; Wimmer, Eckard

Alanine Scanning of Poliovirus 2CATPase Reveals New Genetic Evidence that Capsid Protein/2CATPase Interactions Are Essential for Morphogenesis

JOURNAL OF VIROLOGY

IF3.8

2012-09-15

OAAI

Wang, Chunling; Jiang, Ping; Sand, Claire; Paul, Aniko V.; Wimmer, Eckard

研究方向