Charles E. McKenna - Publications, H-index & Citations

Charles E. McKenna

university of southern california

43H指数

451论文数

6.8K被引数

收录论文 92

发表时间

Big Data and Artificial Intelligence in Cancer Drug Discovery: Promise, Challenges, and Emerging Opportunities 大数据和人工智能在癌症药物发现中的应用：前景、挑战与新兴机遇

Cancers

IF4.4

2026-09-11

OAAI

Fakhar U. Singhera; Justin M. Overhulse; Terrence M. Lee; Jonathan E. Katz; Jerry S. H. Lee; Charles E. McKenna

Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential 人源化念珠菌和NanoBiT分析加速具有抗真菌潜力的Bdf1溴域抑制剂的开发

ADVANCED SCIENCE

IF14.1

2025-01-16

OAAI

Wei, KY; Arlotto, M; Overhulse, JM; Dinh, TA; Zhou, YS; Dupper, NJ; Yang, JY; Kashemirov, BA; Dawi, H; Garnaud, C; Bourgine, G; Mietton, F; Champleboux, M; Larabi, A; Hayat, Y; Indorato, RL; Noirclerc-Savoye, M; Skoufias, D; Cornet, M; Rabut, G; Mckenna, CE; Petosa, C; Govin, J

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-01-25

OAAI

Seebald, Leah M.; Haratipour, Pouya; Jacobs, Michaela R.; Bernstein, Hannah M.; Kashemirov, Boris A.; Mckenna, Charles E.; Imperiali, Barbara

Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis

BONE RESEARCH

IF15

2023-10-18

OAAI

Ren, Youliang; Weeks, Jason; Xue, Thomas; Rainbolt, Joshua; Bentley, Karen L. de Mesy; Shu, Ye; Liu, Yuting; Masters, Elysia; Cherian, Philip; Mckenna, Charles E.; Neighbors, Jeffrey; Ebetino, Frank H.; Schwarz, Edward M.; Sun, Shuting; Xie, Chao

Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2023-09-01

OAAI

Jacobs, Michaela R.; Olivero, Jennifer E.; Choi, Hyun Ok; Liao, Chun-Peng; Kashemirov, Boris A.; Katz, Jonathan E.; Gross, Mitchell E.; McKenna, Charles E.

Microwave-Accelerated McKenna Synthesis of Phosphonic Acids: An Investigation

MOLECULES

IF4.6

2023-04-15

OAAI

Mustafa, Dana; Overhulse, Justin M.; Kashemirov, Boris A.; McKenna, Charles E.

RAB26 and RAB3D Are Direct Transcriptional Targets of MIST1 That Regulate Exocrine Granule Maturation RAB26和RAB3D是调节外分泌颗粒成熟的MIST1的直接转录靶标

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

101

OAAI

Tian, Xiaolin; Jin, Ramon U.; Bredemeyer, Andrew J.; Oates, Edward J.; Blazewska, Katarzyna M.; McKenna, Charles E.; Mills, Jason C.

Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding

JOURNAL OF COMPUTATIONAL CHEMISTRY

IF4.8

2022-10-03

OAAI

Zhou, Yingsheng; Overhulse, Justin M.; Dupper, Nathan J.; Guo, Yanchun; Kashemirov, Boris A.; Wei, Kaiyao; Govin, Jerome; Petosa, Carlo; McKenna, Charles E.

Oral microbial extracellular DNA initiates periodontitis through gingival degradation by fibroblast-derived cathepsin K in mice

COMMUNICATIONS BIOLOGY

IF5.1

2022-09-14

OAAI

Kondo, Takeru; Okawa, Hiroko; Hokugo, Akishige; Shokeen, Bhumika; Sundberg, Oskar; Zheng, Yiying; McKenna, Charles E.; Lux, Renate; Nishimura, Ichiro

Fluorescent risedronate analogue 800CW-pRIS improves tooth extraction-associated abnormal wound healing in zoledronate-treated mice

COMMUNICATIONS MEDICINE

IF6.3

2022-09-05

OAAI

Okawa, Hiroko; Kondo, Takeru; Hokugo, Akishige; Cherian, Philip; Sundberg, Oskar; Campagna, Jesus J.; Kashemirov, Boris A.; John, Varghese; Sun, Shuting; Ebetino, Frank H.; McKenna, Charles E.; Nishimura, Ichiro

Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inerthydroxymethylene diphosphonate 通过使用竞争性的无氧亚甲基二膦酸盐有针对性地从颚骨中去除遗留的双膦酸盐，揭示了双膦酸盐相关的颌骨骨坏死 (BRONJ) 的机制

ELIFE

IF0

2022-08-26

OAAI

Okawa, Hiroko; Kondo, Takeru; Hokugo, Akishige; Cherian, Philip; Campagna, Jesus J.; Lentini, Nicholas A.; Sung, Eric C.; Chiang, Samantha; Lin, Yi-Ling; Ebetino, Frank H.; John, Varghese; Sun, Shuting; McKenna, Charles E.; Nishimura, Ichiro

Bisphosphonates: The role of chemistry in understanding their biological actions and structure-activity relationships, and new directions for their therapeutic use

BONE

IF3.6

2022-03-01

OAAI

Ebetino, Frank H.; Sun, Shuting; Cherian, Philip; Roshandel, Sahar; Neighbors, Jeffrey D.; Hu, Eric; Dunford, James E.; Sedghizadeh, Parish P.; McKenna, Charles E.; Srinivasan, Venkat; Boeckman, Robert K.; Russell, R. Graham G.

Anomeric Fatty Acid Functionalization Prevents Nonenzymatic S-Glycosylation by Monosaccharide Metabolic Chemical Reporters

ACS CHEMICAL BIOLOGY

IF3.8

2021-07-20

OAAI

Pedowitz, Nichole J.; Jackson, Emma G.; Overhulse, Justin M.; McKenna, Charles E.; Kohler, Jennifer J.; Pratt, Matthew R.

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2021-07-15

OAAI

Kempfle, Judith S.; Duro, Marlon, V; Zhang, Andrea; Amador, Carolina D.; Kuang, Richard; Lu, Ryan; Kashemirov, Boris A.; Edge, Albert S.; McKenna, Charles E.; Jung, David H.

Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid

ANTIBIOTICS-BASEL

IF4.6

2021-06-17

OAAI

Adjei-Sowah, Emmanuela; Peng, Yue; Weeks, Jason; Jonason, Jennifer H.; de Mesy Bentley, Karen L.; Masters, Elysia; Morita, Yugo; Muthukrishnan, Gowrishankar; Cherian, Philip; Hu, X. Eric; McKenna, Charles E.; Ebetino, Frank H.; Sun, Shuting; Schwarz, Edward M.; Xie, Chao

Design and Synthesis of Cathepsin-K-Activated Osteoadsorptive Fluorogenic Sentinel (OFS) Probes for Detecting Early Osteoclastic Bone Resorption in a Multiple Myeloma Mouse Model

BIOCONJUGATE CHEMISTRY

IF3.9

2021-05-06

OAAI

Richard, Eric T.; Morinaga, Kenzo; Zheng, Yiying; Sundberg, Oskar; Hokugo, Akishige; Hui, Kimberly; Zhou, Yipin; Sasaki, Hodaka; Kashemirov, Boris A.; Nishimura, Ichiro; McKenna, Charles E.

Bisphosphonates for delivering drugs to bone

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2021-04-10

OAAI

Sun, Shuting; Tao, Jianguo; Sedghizadeh, Parish P.; Cherian, Philip; Junka, Adam F.; Sodagar, Esmat; Xing, Lianping; Boeckman, Robert K., Jr.; Srinivasan, Venkatesan; Yao, Zhenqiang; Boyce, Brendan F.; Lipe, Brea; Neighbors, Jeffrey D.; Russell, R. Graham G.; McKenna, Charles E.; Ebetino, Frank H.

Paradoxical androgen receptor regulation by small molecule enantiomers

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-19

OAAI

Patsch, Katherin; Liu, Chao; Zapotoczny, Grzegorz; Sun, Yuanye; Sura, Harish; Ung, Nolan; Sun, Ren X.; Haliday, Bethany; Yu, Chen; Aljehani, Mayada; Lee, Jerry S. H.; Kashemirov, Boris A.; Agus, David B.; McKenna, Charles E.; Ruderman, Daniel

Completing the β,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and 31P and 19F NMR Correlations with Absolute Configurations

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2020-10-30

PREAI

Haratipour, Pouya; Minard, Corinne; Nakhjiri, Maryam; Negahbani, Amirsoheil; Chamberlain, Brian T.; Osuna, Jorge; Upton, Thomas G.; Zhao, Michelle; Kashemirov, Boris A.; McKenna, Charles E.

Paradoxical androgen receptor regulation by small molecule enantiomers

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Patsch, Katherin; Liu, Chao; Kashemirov, Boris; Sura, Harish; Zapotoczny, Grzegorz; Sun, Yuanye; Shah, Pavan P.; Katz, Jonathan E.; Chilakala, Sujatha; Joo, Ah Young; Ung, Nolan; Aljehani, Maya; Sun, Ren X.; Agus, David B.; Ruderman, Daniel; McKenna, Charles E.

研究方向