Richard Lake - Publications, H-index & Citations

Richard Lake

University of Western Australia

48H指数

269论文数

1.1W被引数

收录论文 54

发表时间

Deletion of SUZ12 improves cancer cell immunogenicity

EUROPEAN JOURNAL OF CANCER

IF7.1

2024-10-01

PREAI

Morales, M. L. Orozco; Farley, K.; Forbes, C.; Chin, W. L.; Lu, J.; Lansley, S. M.; Leslie, C.; Lassmann, T.; Fear, V.; Lake, R. A.; Lesterhuis, W. J.

Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes

ONCOIMMUNOLOGY

IF6.3

2024-04-26

OAAI

Kidman, Joel; Zemek, Rachael M.; Sidhom, John-William; Correa, Debora; Principe, Nicola; Sheikh, Fezaan; Fear, Vanessa S.; Forbes, Catherine A.; Chopra, Abha; Boon, Louis; Zaitouny, Ayham; de Jong, Emma; Holt, Robert A.; Jones, Matt; Millward, Michael J.; Lassmann, Timo; Forrest, Alistair R. R.; Nowak, Anna K.; Watson, Mark; Lake, Richard A.; Lesterhuis, W. Joost; Chee, Jonathan

The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

FRONTIERS IN TOXICOLOGY

IF4.6

2024-04-17

OAAI

Fisher, Scott A.; Patrick, Kimberley; Hoang, Tracy; Marcq, Elly; Behrouzfar, Kiarash; Young, Sylvia; Miller, Timothy J.; Robinson, Bruce W. S.; Bueno, Raphael; Nowak, Anna K.; Lesterhuis, W. Joost; Morahan, Grant; Lake, Richard A.

Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner

BMC CANCER

IF3.4

2024-02-13

OAAI

Tilsed, Caitlin M.; Morales, M. Lizeth Orozco; Zemek, Rachael M.; Gordon, Brianna A.; Piggott, Matthew J.; Nowak, Anna K.; Fisher, Scott A.; Lake, Richard A.; Lesterhuis, W. Joost

CD4+T cells drive an inflammatory, TNF-a/IFN-rich tumor microenvironment responsive to chemotherapy

CELL REPORTS

IF6.9

2022-12-01

OAAI

Tilsed, Caitlin M.; Principe, Nicola; Kidman, Joel; Chin, Wee Loong; Morales, M. Lizeth Orozco; Zemek, Rachael M.; Chee, Jonathan; Islam, Rasa; Fear, Vanessa S.; Forbes, Catherine; Aston, Wayne J.; Jansen, Maud; Chopra, Abha; Lassmann, Timo; Nowak, Anna K.; Fisher, Scott A.; Lake, Richard A.; Lesterhuis, W. Joost

Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice

NATURE COMMUNICATIONS

IF15.7

2022-08-19

OAAI

Zemek, Rachael M.; Chin, Wee Loong; Fear, Vanessa S.; Wylie, Ben; Casey, Thomas H.; Forbes, Cath; Tilsed, Caitlin M.; Boon, Louis; Guo, Belinda B.; Bosco, Anthony; Forrest, Alistair R. R.; Millward, Michael J.; Nowak, Anna K.; Lake, Richard A.; Lassmann, Timo; Lesterhuis, W. Joost

Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action

FRONTIERS IN ONCOLOGY

IF3.3

2022-07-29

OAAI

Tilsed, Caitlin M.; Fisher, Scott A.; Nowak, Anna K.; Lake, Richard A.; Lesterhuis, W. Joost

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-11

OAAI

Principe, Nicola; Aston, Wayne J.; Hope, Danika E.; Tilsed, Caitlin M.; Fisher, Scott A.; Boon, Louis; Dick, Ian M.; Chin, Wee Loong; McDonnell, Alison M.; Nowak, Anna K.; Lake, Richard A.; Chee, Jonathan; Lesterhuis, Willem Joost

Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy

FRONTIERS IN ONCOLOGY

IF3.3

2022-03-24

OAAI

Tilsed, Caitlin M.; Casey, Thomas H.; de Jong, Emma; Bosco, Anthony; Zemek, Rachael M.; Salmons, Joanne; Wan, Graeme; Millward, Michael J.; Nowak, Anna K.; Lake, Richard A.; Lesterhuis, Willem Joost

How to Better Understand the Influence of Host Genetics on Developing an Effective Immune Response to Thoracic Cancers

FRONTIERS IN ONCOLOGY

IF3.3

2021-06-21

OAAI

Behrouzfar, Kiarash; Burton, Kimberley; Mutsaers, Steve E.; Morahan, Grant; Lake, Richard A.; Fisher, Scott A.

Malignant Pleural Effusions-A Window Into Local Anti-Tumor T Cell Immunity?

FRONTIERS IN ONCOLOGY

IF3.3

2021-04-27

OAAI

Principe, Nicola; Kidman, Joel; Lake, Richard A.; Lesterhuis, Willem Joost; Nowak, Anna K.; McDonnell, Alison M.; Chee, Jonathan

Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy 肿瘤浸润效应记忆抗原特异性CD8 T细胞预测对免疫检查点治疗的反应

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-11-12

OAAI

Principe, Nicola; Kidman, Joel; Goh, Siting; Tilsed, Caitlin M.; Fisher, Scott A.; Fear, Vanessa S.; Forbes, Catherine A.; Zemek, Rachael M.; Chopra, Abha; Watson, Mark; Dick, Ian M.; Boon, Louis; Holt, Robert A.; Lake, Richard A.; Nowak, Anna K.; Lesterhuis, Willem Joost; McDonnell, Alison M.; Chee, Jonathan

Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-10-14

OAAI

Kidman, Joel; Principe, Nicola; Watson, Mark; Lassmann, Timo; Holt, Robert A.; Nowak, Anna K.; Lesterhuis, Willem Joost; Lake, Richard A.; Chee, Jonathan

Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

NATURE PROTOCOLS

IF16

2020-04-01

PREAI

Zemek, Rachael M.; Fear, Vanessa S.; Forbes, Cath; de Jong, Emma; Casey, Thomas H.; Boon, Louis; Lassmann, Timo; Bosco, Anthony; Millward, Michael J.; Nowak, Anna K.; Lake, Richard A.; Lesterhuis, W. Joost

Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-02-18

OAAI

Zemek, Rachael M.; Chin, Wee Loong; Nowak, Anna K.; Millward, Michael J.; Lake, Richard A.; Lesterhuis, W. Joost

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2019-07-17

163

OAAI

Zemek, Rachael M.; De Jong, Emma; Chin, Wee Loong; Schuster, Iona S.; Fear, Vanessa S.; Casey, Thomas H.; Forbes, Cath; Dart, Sarah J.; Leslie, Connull; Zaitouny, Ayham; Small, Michael; Boon, Louis; Forrest, Alistair R. R.; Muiri, Daithi O.; Degli-Esposti, Mariapia A.; Millward, Michael J.; Nowak, Anna K.; Lassmann, Timo; Bosco, Anthony; Lake, Richard A.; Lesterhuis, W. Joost

Dexamethasone differentially depletes tumour and peripheral blood lymphocytes and can impact the efficacy of chemotherapy/checkpoint blockade combination treatment

ONCOIMMUNOLOGY

IF6.3

2019-07-13

OAAI

Aston, Wayne J.; Hope, Danika E.; Cook, Alistair M.; Boon, Louis; Dick, Ian; Nowak, Anna K.; Lake, Richard A.; Lesterhuis, W. Joost

Combination immune checkpoint blockade as an effective therapy for mesothelioma 联合免疫检查点阻断治疗间皮瘤的有效方法

ONCOIMMUNOLOGY

IF6.3

2018-07-30

OAAI

Fear, Vanessa S.; Tilsed, Caitlin; Chee, Jonathan; Forbes, Catherine A.; Casey, Thomas; Solin, Jessica N.; Lansley, Sally M.; Lesterhuis, W. Joost; Dick, Ian M.; Nowak, Anna K.; Robinson, Bruce W.; Lake, Richard A.; Fisher, Scott A.

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

BMC CANCER

IF3.4

2017-10-16

160

OAAI

Aston, Wayne J.; Hope, Danika E.; Nowak, Anna K.; Robinson, Bruce W.; Lake, Richard A.; Lesterhuis, W. Joost

Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters

BMC CANCER

IF3.4

2017-06-15

OAAI

McDonnell, Alison M.; Cook, Alistair; Robinson, Bruce W. S.; Lake, Richard A.; Nowak, Anna K.

研究方向