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Combination of Orai1 inhibitor CM5480 with specific therapy mitigates pulmonary hypertension and its cardiac dysfunction Orai1抑制剂CM5480与特异性疗法的联合应用减轻了肺动脉高压及其心脏功能障碍 Willer, Anais Saint-Martin; Ruffenach, Gregoire; Masson, Bastien; El jekmek, Kristelle; Boet, Angele; Adao, Rui; Gourmelon, Mathieu; Beauvais, Antoine; Sabourin, Jessica; Dutheil, Mary; Ghigna, Maria-Rosa; Tesson, Laurent; Menoret, Severine; Anegon, Ignacio; Bauer, Fabrice; de Montpreville, Vincent; Hebbar, Sudarshan; Bras-Silva, Carmen; Stauderman, Kenneth; Humbert, Marc; Mercier, Olaf; Montani, David; Capuano, Veronique; Antigny, Fabrice 分享 收藏
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Changes in social behavior with MAPK2 and KCTD13/CUL3 pathways alterations in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders 在两个新的16 p11.2自闭症谱系障碍综合征的近交大鼠模型中，MAPK2和KCTD13/CUL3途径的社会行为变化 Martin Lorenzo, Sandra; Muniz Moreno, Maria del Mar; Atas, Helin; Pellen, Marion; Nalesso, Valerie; Raffelsberger, Wolfgang; Prevost, Geraldine; Lindner, Loic; Birling, Marie-Christine; Menoret, Severine; Tesson, Laurent; Negroni, Luc; Concordet, Jean-Paul; Anegon, Ignacio; Herault, Yann 分享 收藏
CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury Leuillier, Matthieu; Duflot, Thomas; Menoret, Severine; Messaoudi, Hind; Djerada, Zoubir; Groussard, Deborah; Denis, Raphael G. P.; Chevalier, Laurence; Karoui, Ahmed; Panthu, Baptiste; Thiebaut, Pierre-Alain; Schmitz-Afonso, Isabelle; Nobis, Severine; Campart, Cynthia; Henry, Tiphaine; Sautreuil, Camille; Luquet, Serge H.; Beseme, Olivia; Feliu, Catherine; Peyret, Helene; Nicol, Lionel; Henry, Jean-Paul; Renet, Sylvanie; Mulder, Paul; Wan, Debin; Tesson, Laurent; Heslan, Jean-Marie; Duche, Angeline; Jacques, Sebastien; Ziegler, Frederic; Brunel, Valery; Rautureau, Gilles J. P.; Monteil, Christelle; do Rego, Jean-Luc; do Rego, Jean-Claude; Afonso, Carlos; Hammock, Bruce; Madec, Anne-Marie; Pinet, Florence; Richard, Vincent; Anegon, Ignacio; Guignabert, Christophe; Morisseau, Christophe; Bellien, Jeremy 分享 收藏
IL-34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis IL-34缺乏损害自身免疫性结肠炎模型中的FOXP3 Treg功能并降低免疫耐受稳态 Freuchet, Antoine; Salama, Apolline; Bezie, Severine; Tesson, Laurent; Remy, Severine; Humeau, Romain; Regue, Hadrien; Serazin, Celine; Flippe, Lea; Peterson, Part; Vimond, Nadege; Usal, Claire; Menoret, Severine; Heslan, Jean-Marie; Duteille, Franck; Blanchard, Frederic; Giral, Magali; Colonna, Marco; Anegon, Ignacio; Guillonneau, Carole 分享 收藏
The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection Del Rio, Maria-Luisa; Nguyen, Tuan H.; Tesson, Laurent; Heslan, Jean-Marie; Gutierrez-Adan, Alfonso; Fernandez-Gonzalez, Raul; Gutierrez-Arroyo, Julia; Buhler, Leo; Perez-Simon, Jose-Antonio; Anegon, Ignacio; Rodriguez-Barbosa, Jose-Ignacio 分享 收藏
Overexpression of endothelial β3-adrenergic receptor induces diastolic dysfunction in rats Dhot, Justine; Ferron, Marine; Prat, Valentine; Persello, Antoine; Roul, David; Stevant, David; Guijarro, Damien; Piriou, Nicolas; Aillerie, Virginie; Erraud, Angelique; Toumaniantz, Gilles; Erfanian, Morteza; Tesse, Angela; Grabherr, Amandine; Tesson, Laurent; Menoret, Severine; Anegon, Ignacio; Trochu, Jean-Noel; Steenman, Marja; De Waard, Michel; Rozec, Bertrand; Lauzier, Benjamin; Gauthier, Chantal 分享 收藏
Otoferlin gene editing in sheep via CRISPR-assisted ssODN-mediated Homology Directed Repair Menchaca, A.; dos Santos-Neto, P. C.; Souza-Neves, M.; Cuadro, F.; Mulet, A. P.; Tesson, L.; Chenouard, V; Guiffes, A.; Heslan, J. M.; Gantier, M.; Anegon, I; Crispo, M. 分享 收藏
In Vivo Analysis of Human Immune Responses in Immunodeficient Rats Menoret, Severine; Ouisse, Laure-Helene; Tesson, Laurent; Remy, Severine; Usal, Claire; Guiffes, Aude; Chenouard, Vanessa; Royer, Pierre-Joseph; Evanno, Gwenaelle; Vanhove, Bernard; Piaggio, Eliane; Anegon, Ignacio 分享 收藏
Ceruloplasmin deficiency does not induce macrophagic iron overload: lessons from a new rat model of hereditary aceruloplasminemia Kenawi, Moussa; Rouger, Emmanuel; Island, Marie-Laure; Leroyer, Patricia; Robin, Francois; Remy, Severine; Tesson, Laurent; Anegon, Ignacio; Nay, Kevin; Derbre, Frederic; Brissot, Pierre; Ropert, Martine; Cavey, Thibault; Loreal, Olivier 分享 收藏
Characterization of Kcnk3-Mutated Rat, a Novel Model of Pulmonary Hypertension Lambert, Melanie; Capuano, Veronique; Boet, Angele; Tesson, Laurent; Bertero, Thomas; Nakhleh, Morad K.; Remy, Severine; Anegon, Ignacio; Pechoux, Christine; Hautefort, Aurelie; Rucker-Martin, Catherine; Manoury, Boris; Domergue, Valrie; Mercier, Olaf; Girerd, Barbara; Montani, David; Perros, Frederic; Humbert, Marc; Antigny, Fabrice 分享 收藏
Immunophenotype of a Rat Model of Duchenne's Disease and Demonstration of Improved Muscle Strength After Anti-CD45RC Antibody Treatment Ouisse, Laure-Helene; Remy, Severine; Lafoux, Aude; Larcher, Thibaut; Tesson, Laurent; Chenouard, Vanessa; Guillonneau, Carole; Brusselle, Lucas; Vimond, Nadege; Rouger, Karl; Pereon, Yann; Chenouard, Alexis; Gras-Le Guen, Christele; Braudeau, Cecile; Josien, Regis; Huchet, Corinne; Anegon, Ignacio 分享 收藏
Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-like Autoimmune Disease Ossart, Jason; Moreau, Anne; Autrusseau, Elodie; Menoret, Severine; Martin, Jerome C.; Besnard, Marine; Ouisse, Laure-Helene; Tesson, Laurent; Flippe, Lea; Kisand, Kai; Peterson, Paert; Hubert, Francois-Xavier; Anegon, Ignacio; Josien, Regis; Guillonneau, Carole 分享 收藏
Generation of Immunodeficient Rats With Rag1 and Il2rg Gene Deletions and Human Tissue Grafting Models Menoret, Severine; Ouisse, Laure-Helene; Tesson, Laurent; Delbos, Frederic; Garnier, Delphine; Remy, Severine; Usal, Claire; Concordet, Jean-Paul; Giovannangeli, Carine; Chenouard, Vanessa; Brusselle, Lucas; Merieau, Emmanuel; Nerriere-Daguin, Veronique; Duteille, Franck; Bellier-Waast, Frederique; Fraichard, Alexandre; Nguyen, Tuan H.; Anegon, Ignacio 分享 收藏
CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair Charpentier, M.; Khedher, A. H. Y.; Menoret, S.; Brion, A.; Lamribet, K.; Dardillac, E.; Boix, C.; Perrouault, L.; Tesson, L.; Geny, S.; De Cian, A.; Itier, J. M.; Anegon, I.; Lopez, B.; Giovannangeli, C.; Concordet, J. P. 分享 收藏
Generation of gene-edited rats by delivery of CRISPR/Cas9 protein and donor DNA into intact zygotes using electroporation Remy, Severine; Chenouard, Vanessa; Tesson, Laurent; Usal, Claire; Menoret, Severine; Brusselle, Lucas; Heslan, Jean-Marie; Tuan Huan Nguyen; Bellien, Jeremy; Merot, Jean; De Cian, Anne; Giovannangeli, Carine; Concordet, Jean-Paul; Anegon, Ignacio 分享 收藏
Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats Jung, Chris J.; Menoret, Severine; Brusselle, Lucas; Tesson, Laurent; Usal, Claire; Chenouard, Vanessa; Remy, Severine; Ouisse, Laure-Helene; Poirier, Nicolas; Vanhove, Bernard; de Jong, Pieter J.; Anegon, Ignacio 分享 收藏
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