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Chris Twelves

university of leeds and leeds teaching hospitals nhs trust

57H指数
328论文数
1.6W被引数
收录论文 79
发表时间
Oncology drug development in the UK: analysis of the past 25 years and focus on the 2026 reboot of the clinical trial regulatory framework英国肿瘤药物研发:过去25年的分析及对2026年临床试验监管框架重启的关注
err2026-07-23
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errPaulina Czajka-Francuz; Chris Twelves; James Spicer; Archana Munje; Laura Vidal; Ruth Plummer; Dinesh Mistry; Maksym Novikov; Jim Bush; Gopalakrishnan Srinivasan; Soma Das; Sharan Sandhu; Vikram Bohra; Chinmayee Joshi; Ken Morrison; Suvarna Chavan; Fiona Thistlethwaite; Andrew Walding; Glen Clack; Michael George; Debashis Sarker; Raghib Ali; Sarah P. Blagden; Thomas R. Jeffry Evans; Kamal S. Saini
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Real world study of sacituzumab govitecan in metastatic triple-negative breast cancer in the United Kingdom
err2024-04-24
err5
errOAAI
errHanna, Daire; Merrick, Sophie; Ghose, Aruni; Devlin, Michael John; Yang, Dorothy D.; Phillips, Edward; Okines, Alicia; Chopra, Neha; Papadimatraki, Elisavet; Ross, Kirsty; Macpherson, Iain; Boh, Zhuang Y.; Michie, Caroline O.; Swampillai, Angela; Gupta, Sunnia; Robinson, Tim; Germain, Lewis; Twelves, Chris; Atkinson, Charlotte; Konstantis, Apostolos; Riddle, Pippa; Cresti, Nicola; Naik, Jay D.; Borley, Annabel; Guppy, Amy; Schmid, Peter; Phillips, Melissa
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A Phase I trial of AVA6000, a Fibroblast Activation Protein (FAP)-released and tumor microenvironment (TME)-targeted doxorubicin peptide drug conjugate in patients with FAP-positive solid tumors
err2024-04-05
err1
PREAI
errBanerji, Udai; Cook, Natalie; Anthoney, Alan; Plummer, Ruth; Tap, William D.; Evans, Jeffry T.; Cranmer, Lee D.; Plummer, Christopher; Loadman, Paul; Lahu, Gezim; Jones, Huw S.; Kinnersley, Nelson; McLaughlin, Fiona; Twelves, Chris
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Aromatase inhibition plus/minus Src inhibitor saracatinib (AZD0530) in advanced breast cancer therapy (ARISTACAT): a randomised phase II study
err2023-03-02
err7
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errOswald, Ailsa J.; Symeonides, Stefan N.; Wheatley, Duncan; Chan, Stephen; Brunt, Adrian Murray; McAdam, Karen; Schmid, Peter; Waters, Simon; Poole, Christopher; Twelves, Chris; Perren, Timothy; Bartlett, John; Piper, Tammy; Chisholm, Eve Macdonald; Welsh, Michelle; Hill, Robert; Hopcroft, Lisa E. M.; Barrett-Lee, Peter; Cameron, David A.
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A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results
err2022-08-01
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errWinter, Matthew; Coleman, Rob; Kendall, Jessica; Palmieri, Carlo; Twelves, Chris; Howell, Sacha; MacPherson, Iain; Wilson, Caroline; Purohit, Kash; Gath, Jacqui; Taylor, Christine; Eastell, Richard; Murden, Geraldine; Brown, Sarah R.; Rathbone, Emma; Brown, Janet
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Antibody-drug conjugates, immune-checkpoint inhibitors, and their combination in breast cancer therapeutics抗体-药物结合物,免疫检查点抑制剂及其在乳腺癌治疗中的组合
err2021-06-15
err31
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errSaini, Kamal S.; Punie, Kevin; Twelves, Chris; Bortini, Stefanella; de Azambuja, Evandro; Anderson, Steven; Criscitiello, Carmen; Awada, Ahmad; Loi, Sherene
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Reimagining Global Oncology Clinical Trials for the Postpandemic Era: A Call to Arms
err2020-11-01
err15
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errSaini, Kamal S.; de las Heras, Begona; Plummer, Ruth; Moreno, Victor; Romano, Marco; de Castro, Javier; Aftimos, Philippe; Fredriksson, Judy; Bhattacharyya, Gouri Shankar; Olivo, Martin Sebastian; Schiavon, Gaia; Punie, Kevin; Garcia-Foncillas, Jesus; Rogata, Ernesto; Pfeiffer, Richie; Orbegoso, Cecilia; Morrison, Kenneth; Curigliano, Giuseppe; Chin, Lynda; Saini, Monika Lamba; Rekdal, Oystein; Anderson, Steven; Cortes, Javier; Leone, Manuela; Dancey, Janet; Twelves, Chris; Awada, Ahmad
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Efficacy of eribulin for metastatic breast cancer based on localization of specific secondary metastases: a post hoc analysis
err2020-07-08
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errO'Shaughnessy, Joyce; Cortes, Javier; Twelves, Chris; Goldstein, Lori J.; Alexis, Karenza; Xie, Ran; Barrios, Carlos; Ueno, Takayuki
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Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy
err2020-06-22
err29
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errSaini, Kamal S.; Lanza, Carlo; Romano, Marco; de Azambuja, Evandro; Cortes, Javier; de las Heras, Begona; de Castro, Javier; Lamba Saini, Monika; Loibl, Sibylle; Curigliano, Giuseppe; Twelves, Chris; Leone, Manuela; Patnaik, Mrinal M.
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Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours
err2020-03-12
err25
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errde Bono, Johann; Lin, Chia-Chi; Chen, Li-Tzong; Corral, Jesus; Michalarea, Vasiliki; Rihawi, Karim; Ong, Michael; Lee, Jih-Hsiang; Hsu, Chih-Hung; Yang, James Chih-Hsin; Shiah, Her-Shyong; Yen, Chia-Jui; Anthoney, Alan; Jove, Maria; Buschke, Susanne; Fuertig, Rene; Schmid, Ulrike; Goeldner, Rainer-Georg; Strelkowa, Natalja; Huang, Dennis Chin-Lun; Bogenrieder, Thomas; Twelves, Chris; Cheng, Ann-Lii
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Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance
err2019-09-01
err25
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errJove, Maria; Spencer, Jade; Clench, Malcolm; Loadman, Paul M.; Twelves, Chris
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Cellular Uptake and Efflux of Palbociclib In Vitro in Single Cell and Spheroid Models
err2019-08-01
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errJove, M.; Spencer, J. A.; Hubbard, M. E.; Holden, E. C.; O'Dea, R. D.; Brook, B. S.; Phillips, R. M.; Smye, S. W.; Loadman, P. M.; Twelves, C. J.
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ATTAIN: Phase III study of etirinotecan pegol versus treatment of physician's choice in patients with metastatic breast cancer and brain metastases
err2019-05-10
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errTripathy, Debu; Tolaney, Sara M.; Seidman, Andrew D.; Anders, Carey K.; Ibrahim, Nuhad; Rugo, Hope S.; Twelves, Chris; Dieras, Veronique; Mueller, Volkmar; Tagliaferri, Mary; Hannah, Alison L.; Cortes, Javier
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A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine
err2019-02-20
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errTwelves, Chris; Anthoney, Alan; Savulsky, Claudio, I; Guo, Matthew; Reyderman, Larisa; Cresti, Nicola; Semiglazov, Vladimir; Timcheva, Constanta; Zubairi, Ishtiaq; Morrison, Rosemary; Plummer, Ruth; Evans, T. R. Jeffry
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Preclinical intratumoral pharmacokinetics (PK) of capecitabine (Cap) given plus /- eribulin (Eri)
err2018-07-01
err0
PREAI
errJove Casulleras, Maria; Spencer, Jade; Loadman, Paul; Clench, Malcolm; Shnyder, Steve; Cooper, Patricia; Russo, Cristina; Race, Amanda; Salazar, Ramon; Twelves, Chris
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Intracellular pharmacokinetics of 5FU and palbociclib: Uptake and efflux in disaggregated cells and 3D models
err2017-07-01
err1
PREAI
errJove, Maria; Loadman, Paul; Spencer, Jade; Sulayman, Lava; Wicks, Jo; Race, Amanda; Twelves, Chris
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Prolonged survival in patients with breast cancer and a history of brain metastases: results of a preplanned subgroup analysis from the randomized phase III BEACON trial
err2017-06-13
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errCortes, Javier; Rugo, Hope S.; Awada, Ahmad; Twelves, Chris; Perez, Edith A.; Im, Seock-Ah; Gomez-Pardo, Patricia; Schwartzberg, Lee S.; Dieras, Veronique; Yardley, Denise A.; Potter, David A.; Mailliez, Audrey; Moreno-Aspitia, Alvaro; Ahn, Jin-Seok; Zhao, Carol; Hoch, Ute; Tagliaferri, Mary; Hannah, Alison L.; O'Shaughnessy, Joyce
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