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收藏The effects of inhaled corticosteroids on healthy airways
Hinks, Timothy; Marchi, Emanuele; Richardson, Matthew; Chachi, Latifa; Symon, Fiona; Rajasekar, Poojitha; Clifford, Rachel; Hargadon, Beverley; Austin, Cary; Siddiqui, Salman; Mar, Jordan; Arron, Joseph; Choy, David; Bradding, Peter 分享 收藏 The effects of inhaled corticosteroids on healthy airwaysMarchi, Emanuele; Hinks, Timothy S. C.; Richardson, Matthew; Khalfaoui, Latifa; Symon, Fiona A.; Rajasekar, Poojitha; Clifford, Rachel; Hargadon, Beverley; Austin, Cary D.; Macisaac, Julia L.; Kobor, Michael S.; Siddiqui, Salman; Mar, Jordan S.; Arron, Joseph R.; Choy, David F.; Bradding, Peter 分享 收藏 Relative abundance of Haemophilus as a component of the respiratory microbiome is not associated with airway epithelial MUC5AC staining嗜血杆菌作为呼吸道微生物组的组成部分的相对丰度与气道上皮MUC5AC染色无关Diver, Sarah; Haldar, Kairobi; Khalfaoui, Latifa; Symon, Fiona; Couillard, Simon; Hargadon, Beverley; Chaudhuri, Rekha; Bicknell, Steve; Mansur, Adel; Shrimanker, Rahul; Hinks, Timothy; Pavord, Ian; Fowler, Stephen; Brown, Vanessa; Mcgarvey, Lorcan; Heaney, Liam; Austin, Cary; Howarth, Peter; Arron, Joseph; Choy, David; Bradding, Peter; Haldar, Koirobi 分享 收藏 Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitisChavarria-Smith, Joseph; Chiu, Cecilia P. C.; Jackman, Janet K.; Yin, Jianping; Zhang, Juan; Hackney, Jason A.; Lin, Wei-Yu; Tyagi, Tulika; Sun, Yonglian; Tao, Janet; Dunlap, Debra; Morton, William D.; Ghodge, Swapnil, V; Maun, Henry R.; Li, Hong; Hernandez-Barry, Hilda; Loyet, Kelly M.; Chen, Emily; Liu, John; Tam, Christine; Yaspan, Brian L.; Cai, Hao; Balazs, Mercedesz; Arron, Joseph R.; Li, Jing; Wittwer, Arthur J.; Pappu, Rajita; Austin, Cary D.; Lee, Wyne P.; Lazarus, Robert A.; Sudhamsu, Jawahar; Koerber, James T.; Yi, Tangsheng 分享 收藏 Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in Acinetobacter baumannii先前未表征的脂蛋白lirL的缺失赋予鲍曼不动杆菌对II型信号肽酶抑制剂的抗性Huang, Ke-Jung; Pantua, Homer; Diao, Jingyu; Skippington, Elizabeth; Volny, Michael; Sandoval, Wendy; Tiku, Varnesh; Peng, Yutian; Sagolla, Meredith; Yan, Donghong; Kang, Jing; Katakam, Anand Kumar; Michaelian, Nairie; Reichelt, Mike; Tan, Man-Wah; Austin, Cary D.; Xu, Min; Hanan, Emily; Kapadia, Sharookh B. 分享 收藏 Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma气道重塑而不是细胞浸润是2型细胞因子生物标志物-高和低重度哮喘的特征Khalfaoui, Latifa; Symon, Fiona A.; Couillard, Simon; Hargadon, Beverley; Chaudhuri, Rekha; Bicknell, Steve; Mansur, Adel H.; Shrimanker, Rahul; Hinks, Timothy S. C.; Pavord, Ian D.; Fowler, Stephen J.; Brown, Vanessa; McGarvey, Lorcan P.; Heaney, Liam G.; Austin, Cary D.; Howarth, Peter H.; Arron, Joseph R.; Choy, David F.; Bradding, Peter 分享 收藏 Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthmaGuidi, Riccardo; Xu, Daqi; Choy, David F.; Ramalingam, Thirumalai R.; Lee, Wyne P.; Modrusan, Zora; Liang, Yuxin; Marsters, Scot; Ashkenazi, Avi; Huynh, Alison; Mills, Jessica; Flanagan, Sean; Hambro, Shannon; Nunez, Victor; Leong, Laurie; Cook, Ashley; Tran, Tiffany Hao; Austin, Cary D.; Cao, Yi; Clarke, Christine; Panettieri, Reynold A., Jr.; Koziol-White, Cynthia; Jester, William F., Jr.; Wang, Fen; Wilson, Mark S. 分享 收藏 Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative ActivityVerma, Vishal A.; Wang, Lan; Labadie, Sharada S.; Liang, Jun; Sellers, Benjamin D.; Wang, Jian; Dong, Liting; Wang, Qiuyue; Zhang, Shuang; Xu, Zhongya; Zhang, Yexia; Niu, Yanan; Wang, Xinxin; Wai, John; Koehler, Michael F. T.; Hu, Huiyong; Alexander, Mary Kate; Nishiyama, Mireille; Miu, Anh; Xu, Yiming; Pang, Jodie; Katakam, Anand K.; Reichelt, Michael; Austin, Cary D.; Ho, Hoangdung; Payandeh, Jian; Koth, Christopher M. 分享 收藏 Oncostatin M expression induced by bacterial triggers drives airway inflammatory and mucus secretion in severe asthma细菌触发物诱导的制瘤素M表达驱动严重哮喘的气道炎症和粘液分泌Headland, Sarah E.; Dengler, Hart S.; Xu, Daqi; Teng, Grace; Everett, Christine; Ratsimandresy, Rojo A.; Yan, Donghong; Kang, Jing; Ganeshan, Kirthana; Nazarova, Evgeniya, V; Gierke, Sarah; Wedeles, Christopher J.; Guidi, Riccardo; DePianto, Daryle J.; Morshead, Katrina B.; Huynh, Alison; Mills, Jessica; Flanagan, Sean; Hambro, Shannon; Nunez, Victor; Klementowicz, Joanna E.; Shi, Yongchang; Wang, Jianyong; Bevers, Jack; Ramirez-Carrozzi, Vladimir; Pappu, Rajita; Abbas, Alex; Vander Heiden, Jason; Choy, David F.; Yadav, Rajbharan; Modrusan, Zora; Panettieri, Reynold A., Jr.; Koziol-White, Cynthia; Jester, William F., Jr.; Jenkins, Brendan J.; Cao, Yi; Clarke, Christine; Austin, Cary; Lafkas, Daniel; Xu, Min; Wolters, Paul J.; Arron, Joseph R.; West, Nathaniel R.; Wilson, Mark S. 分享 收藏 Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infectionEntwistle, Lewis; Aegerter, Helena; Czieso, Stephanie; Amaniti, Eleni; Guidi, Riccardo; Sesay, Abdul; Nikolov, Nikolay; Chakravaty, Probir; Huynh, Alison; Mills, Jessica; Flanagan, Sean; Hambro, Shannon; Nunez, Victor; Cao, Yi; Clarke, Christine; Martzall, Angela; Leong, Laurie; Wilson, Dennis; Austin, Cary; Wilson, Mark 分享 收藏 A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatmentBalestrini, Alessia; Joseph, Victory; Dourado, Michelle; Reese, Rebecca M.; Shields, Shannon D.; Rouge, Lionel; Bravo, Daniel D.; Chernov-Rogan, Tania; Austin, Cary D.; Chen, Huifen; Wang, Lan; Villemure, Elisia; Shore, Daniel G. M.; Verma, Vishal A.; Hu, Baihua; Chen, Yong; Leong, Laurie; Bjornson, Chris; Hotel, Kathy; Gogineni, Alvin; Lee, Wyne P.; Suto, Eric; Wu, Xiumin; Liu, John; Zhang, Juan; Gandham, Vineela; Wang, Jianyong; Payandeh, Jian; Ciferri, Claudio; Estevez, Alberto; Arthur, Christopher P.; Kortmann, Jens; Wong, Ryan L.; Heredia, Jose E.; Doerr, Jonas; Jung, Min; Vander Heiden, Jason A.; Roose-Girma, Merone; Tam, Lucinda; Barck, Kai H.; Carano, Richard A. D.; Ding, Han Ting; Brillantes, Bobby; Tam, Christine; Yang, Xiaoying; Gao, Simon S.; Ly, Justin Q.; Liu, Liling; Chen, Liuxi; Liederer, Bianca M.; Lin, Joseph H.; Magnuson, Steven; Chen, Jun; Hackos, David H.; Elstrott, Justin; Rohou, Alexis; Safina, Brian S.; Volgraf, Matthew; Bauer, Rebecca N.; Riol-Blanco, Lorena 分享 收藏 Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal PeptidasePantua, Homer; Skippington, Elizabeth; Braun, Marie-Gabrielle; Noland, Cameron L.; Diao, Jingyu; Peng, Yutian; Gloor, Susan L.; Yan, Donghong; Kang, Ling; Katakam, Anand Kumar; Reeder, Janina; Castanedo, Georgette M.; Garland, Keira; Komuves, Laszlo; Sagolla, Meredith; Austin, Cary D.; Murray, Jeremy; Xu, Yiming; Modrusan, Zora; Xu, Min; Hanan, Emily J.; Kapadia, Sharookh B. 分享 收藏 A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)Austin, Cary D.; Gonzalez Edick, Melissa; Ferrando, Ronald E.; Solon, Margaret; Baca, Miriam; Mesh, Kathryn; Bradding, Peter; Gauvreau, Gail M.; Sumino, Kaharu; FitzGerald, J. Mark; Israel, Elliot; Bjermer, Lief; Bourdin, Arnaud; Arron, Joseph R.; Choy, David F.; Olsson, Julie K.; Abreu, Francis; Howard, Monet; Wong, Kit; Cai, Fang; Peng, Kun; Putnam, Wendy S.; Holweg, Cecile T. J.; Matthews, John G.; Kraft, Monica; Woodruff, Prescott G. 分享 收藏 The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cellsCorzo, Cesar A.; Varfolomeev, Eugene; Setiadi, A. Francesca; Francis, Ross; Klabunde, Sha; Senger, Kate; Sujatha-Bhaskar, Swathi; Drobnick, Joy; Do, Steven; Suto, Eric; Huang, Zhiyu; Eastham-Anderson, Jeffrey; Katewa, Arna; Pang, Jodie; Domeyer, Melanie; Dela Cruz, Christopher; Paler-Martinez, Andres; Lau, Vivian W. C.; Hadadianpour, Azadeh; Ramirez-Carrozi, Vladimir; Sun, Yonglian; Bao, Katherine; Xu, Daqi; Hunley, Emily; Brightbill, Hans D.; Warming, Soren; Roose-Girma, Merone; Wong, Alfred; Tam, Lucinda; Emson, Claire L.; Crawford, James J.; Young, Wendy B.; Pappu, Rajita; McKenzie, Brent S.; Asghari, Vida; Vucic, Domagoj; Hackney, Jason A.; Austin, Cary D.; Lee, Wyne P.; Lekkerkerker, Annemarie; Ghilardi, Nico; Bryan, Marian C.; Kiefer, James R.; Townsend, Michael J.; Zarrin, Ali A. 分享 收藏 A Randomized, Placebo-Controlled Trial Evaluating Effects of Lebrikizumab on Airway Eosinophilic Inflammation and Remodeling in Uncontrolled Asthma (CLAVIER)Austin, Cary; Edick, Melissa; Ferrando, Ronald; Solon, Margaret; Baca, Miriam; Mesh, Kathryn; Bradding, Peter; Gauvreau, Gail; Sumino, Kaharu; Fitzgerald, Mark; Israel, Eliott; Bjermer, Leif; Bourdin, Arnaud; Arron, Joseph; Choy, David; Olsson, Julie; Abreu, Francis; Howard, Monet; Wong, Kit; Cai, Fang; Peng, Kun; Putman, Wendy; Holweg, Cecile; Matthews, John; Kraft, Monica; Woodruff, Prescott 分享 收藏 Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and CancerCSF1和IL34在巨噬细胞稳态，炎症和癌症中的功能Lin, WeiYu; Xu, Daqi; Austin, Cary D.; Caplazi, Patrick; Senger, Kate; Sun, Yonglian; Jeet, Surinder; Young, Judy; Delarosa, Donnie; Suto, Eric; Huang, Zhiyu; Zhang, Juan; Yan, Donghong; Corzo, Cesar; Barck, Kai; Rajan, Sharmila; Looney, Carrie; Gandham, Vineela; Lesch, Justin; Liang, Wei-Ching; Mai, Elaine; Ngu, Hai; Ratti, Navneet; Chen, Yongmei; Misner, Dinah; Lin, Tori; Danilenko, Dimitry; Katavolos, Paula; Doudemont, Estelle; Uppal, Hirdesh; Eastham, Jeffrey; Mak, Judy; de Almeida, Patricia E.; Bao, Katherine; Hadadianpour, Azadeh; Keir, Mary; Carano, Richard A. D.; Diehl, Lauri; Xu, Min; Wu, Yan; Weimer, Robby M.; DeVoss, Jason; Lee, Wyne P.; Balazs, Mercedesz; Walsh, Kevin; Alatsis, Kathila R.; Martin, Flavius; Zarrin, Ali A. 分享 收藏 Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis哮喘的气道病理异质性: 使用拓扑数据分析可视化疾病微簇Siddiqui, Salman; Shikotra, Aarti; Richardson, Matthew; Doran, Emma; Choy, David; Bell, Alex; Austin, Cary D.; Eastham-Anderson, Jeffrey; Hargadon, Beverley; Arron, Joseph R.; Wardlaw, Andrew; Brightling, Christopher E.; Heaney, Liam G.; Bradding, Peter 分享 收藏 NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosusBrightbill, Hans D.; Suto, Eric; Blaquiere, Nicole; Ramamoorthi, Nandhini; Sujatha-Bhaskar, Swathi; Gogol, Emily B.; Castanedo, Georgette M.; Jackson, Benjamin T.; Kwon, Youngsu C.; Haller, Susan; Lesch, Justin; Bents, Karin; Everett, Christine; Kohli, Pawan Bir; Linge, Sandra; Christian, Laura; Barrett, Kathy; Jaochico, Allan; Berezhkovskiy, Leonid M.; Fan, Peter W.; Modrusan, Zora; Veliz, Kelli; Townsend, Michael J.; DeVoss, Jason; Johnson, Adam R.; Godemann, Robert; Lee, Wyne P.; Austin, Cary D.; McKenzie, Brent S.; Hackney, Jason A.; Crawford, James J.; Staben, Steven T.; Ismaili, Moulay H. Alaoui; Wu, Lawren C.; Ghilardi, Nico 分享 收藏 分享 收藏 
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