未登录 RETRACTION: MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex Konopleva, M.; Milella, M.; Ruvolo, P.; Watts, J. C.; Ricciardi, M. R.; Korchin, B.; Teresa, McQueen; Bornmann, William; Tsao, T.; Bergamo, P.; Mak, D. H.; Chen, W.; McCubrey, J.; Tafuri, A.; Andreeff, M. 分享 收藏
AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3- ITD acute myeloid leukemia Post, Sean M.; Ma, Huaxian; Malaney, Prerna; Zhang, Xiaorui; Aitken, Marisa J. L.; Mak, Po Yee; Ruvolo, Vivian R.; Yasuhiro, Tomoko; Kozaki, Ryohei; Chan, Lauren E.; Ostermann, Lauren B.; Konopleva, Marina; Carter, Bing Z.; DiNardo, Courtney; Andreeff, Michael D.; Khoury, Joseph D.; Ruvolo, Peter P. 分享 收藏
RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences van Dijk, Anneke D.; Griffen, Ti'ara L.; Qiu, Yihua H.; Hoff, Fieke W.; Toro, Endurance; Ruiz, Kevin; Ruvolo, Peter P.; Lillard, James W., Jr.; de Bont, Eveline S. J. M.; Burger, Jan A.; Wierda, William; Kornblau, Steven M. 分享 收藏
GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals Abrams, Stephen L.; Akula, Shaw M.; Meher, Akshaya K.; Steelman, Linda S.; Gizak, Agnieszka; Duda, Przemyslaw; Rakus, Dariusz; Martelli, Alberto M.; Ratti, Stefano; Cocco, Lucio; Montalto, Giuseppe; Cervello, Melchiorre; Ruvolo, Peter; Libra, Massimo; Falzone, Luca; Candido, Saverio; McCubrey, James A. 分享 收藏
Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization RNA剪接因子SF3B1的突变通过MYC稳定促进肿瘤发生 Liu, Zhaoqi; Yoshimi, Akihide; Wang, Jiguang; Cho, Hana; Lee, Stanley Chun-Wei; Ki, Michelle; Bitner, Lillian; Chu, Timothy; Shah, Harshal; Liu, Bo; Mato, Anthony R.; Ruvolo, Peter; Fabbri, Giulia; Pasqualucci, Laura; Abdel-Wahab, Omar; Rabadan, Raul 分享 收藏
A heavy metal baseline score predicts outcome in acute myeloid leukemia Ohanian, Maro; Telouk, Philippe; Kornblau, Steven; Albarede, Francis; Ruvolo, Peter; Tidwell, Rebecca S. S.; Plesa, Adriana; Kanagal-Shamanna, Rashmi; Matera, Eva-Laure; Cortes, Jorge; Carson, Arch; Dumontet, Charles 分享 收藏
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S63845, a novel BH3 mimetic Mcl-1 inhibitor synergizes with midostaurin to induce potent apoptosis in acute myeloid leukemia cells carrying FLT3-ITD mutations Skwarska, Anna; Zhang, Qi; Herbrich, Shelley M.; Baran, Natalia; Halilovic, Ensar; Ruvolo, Peter; Ruvolo, Vivian; Morris, Erick; Wei, Andrew; Moujalled, Donia; Andreff, Michael; Konopleva, Marina 分享 收藏
LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML Ruvolo, Peter P.; Hu, Chenyue W.; Qiu, Yihua; Ruvolo, Vivian R.; Go, Robin L.; Hubner, Stefan E.; Coombes, Kevin R.; Andreeff, Michael; Qutub, Amina A.; Kornblau, Steven M. 分享 收藏
Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival Kornblau, Steven M.; Ruvolo, Peter P.; Wang, Rui-Yu; Battula, V. Lokesh; Shpall, Elizabeth J.; Ruvolo, Vivian R.; McQueen, Teresa; Qui, YiHua; Zeng, Zhihong; Pierce, Sherry; Jacamo, Rodrigo; Yoo, Suk-Young; Le, Phuong M.; Sun, Jeffrey; Hail, Numsen, Jr.; Konopleva, Marina; Andreeff, Michael 分享 收藏
The CXCR4-STAT3-IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide Shaim, Hila; Estrov, Zeev; Harris, David; Sanabria, Mayra Hernandez; Liu, Zhiming; Ruvolo, Peter; Thompson, Phillip A.; Ferrajoli, Alessandra; Daher, May; Burger, Jan; Muftuoglu, Muharrem; Imahashi, Nobuhiko; Li, Li; Liu, Enli; Alsuliman, Abdullah Saleh; Basar, Rafet; Kerbauy, Lucila Nassif; Sobieski, Catherine; Gokdemir, Elif; Kondo, Kayo; Wierda, William; Keating, Michael; Shpall, Elizabeth J.; Rezvani, Katayoun 分享 收藏
Anexelekto /MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms Ruvolo, Peter P.; Ma, Huaxian; Ruvolo, Vivian R.; Zhang, Xiaorui; Mu, Hong; Schober, Wendy; Hernandez, Ivonne; Gallardo, Miguel; Khoury, Joseph D.; Cortes, Jorge; Andreeff, Michael; Post, Sean M. 分享 收藏
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Defining the immune checkpoint landscape of acute myeloid leukemia (AML) Dever, Naval; Basu, Sreyashi; Garcia-Manero, Guillermo; Cortes, Jorge; Ravandi, Farhad; Kornblau, Steven; Konopleva, Marina; Andreeff, Michael; Borthakur, Gautam; Jain, Nitin; Wierda, William; Verstovsek, Srdan; Ruvolo, Peter; Kadia, Tapan; Matthews, Jairo; Flores, Wilmer; Yang, Hui; Bueso-Ramos, Carlos; Somani, Narmeen; Blando, Jorge; Allison, James; Kantarjian, Hagop; Sharma, Padmanee 分享 收藏
ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies Ishizawa, Jo; Kojima, Kensuke; Chachad, Dhruv; Ruvolo, Peter; Ruvolo, Vivian; Jacamo, Rodrigo O.; Borthakur, Gautam; Mu, Hong; Zeng, Zhihong; Tabe, Yoko; Allen, Joshua E.; Wang, Zhiqiang; Ma, Wencai; Lee, Hans C.; Orlowski, Robert; Sarbassov, Dos D.; Lorenzi, Philip L.; Huang, Xuelin; Neelapu, Sattva S.; McDonnell, Timothy; Miranda, Roberto N.; Wang, Michael; Kantarjian, Hagop; Konopleva, Marina; Davis, R. Eric; Andreeff, Michael 分享 收藏
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Ceramide promotes apoptosis in chronic myelogenous leukemia-derived K562 cells by a mechanism involving caspase-8 and JNK Nica, Alina Felicia; Tsao, Chun Chui; Watt, Julie C.; Jiffar, Tilahun; Kurinna, Svitlana; Jurasz, Paul; Konopleva, Marina; Andreeff, Michael; Radomski, Marek W.; Ruvolo, Peter P. 分享 收藏
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