未登录 Small Molecule Inhibitors for Precise Inhibition of Alpha-Synuclein Oligomer Generation in Parkinson's Disease Thomson, John; Cridland, Andrew; Ball, Sarah; Staats, Roxine; Pandey, Samata; Cruz, Marta Castellana; Pisani, Katarina; Meisl, Georg; Kitchen-Smith, Isaac; Yang, Xiaoting; Mannini, Benedetta; Pollack, Scott; Rajah, Luke; Brewerton, Suzanne; Habchi, Johnny; Plowright, Alleyn 分享 收藏
分享 收藏
分享 收藏
Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework Durek, Thomas; Kaas, Quentin; White, Andrew M.; Weidmann, Joachim; Fuaad, Abdullah Ahmad; Cheneval, Olivier; Schroeder, Christina, I; de Veer, Simon J.; Dellsen, Anita; Osterlund, Torben; Larsson, Niklas; Knerr, Laurent; Bauer, Udo; Plowright, Alleyn T.; Craik, David J. 分享 收藏
Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis Mishra, Anurag; Castaneda, Tamara R.; Bader, Erik; Elshorst, Bettina; Cummings, Sheila; Scherer, Petra; Bangari, Dinesh S.; Loewe, Claudia; Schreuder, Herman; Poverlein, Christoph; Helms, Mike; Jones, Seth; Zech, Gernot; Licher, Thomas; Wagner, Michael; Schudok, Manfred; de Hoop, Meltsje; Plowright, Alleyn T.; Atzrodt, Jens; Kannt, Aimo; Laitinen, Iina; Derdau, Volker 分享 收藏
A protein tertiary structure mimetic modulator of the Hippo signalling pathway Adihou, Helene; Gopalakrishnan, Ranganath; Foerster, Tim; Gueret, Stephanie M.; Gasper, Raphael; Geschwindner, Stefan; Garcia, Carmen Carrillo; Karatas, Hacer; Pobbati, Ajaybabu, V; Vazquez-Chantada, Mercedes; Davey, Paul; Wassvik, Carola M.; Pang, Jeremy Kah Sheng; Soh, Boon Seng; Hong, Wanjin; Chiarparin, Elisabetta; Schade, Dennis; Plowright, Alleyn T.; Valeur, Eric; Lemurell, Malin; Grossmann, Tom N.; Waldmann, Herbert 分享 收藏
分享 收藏
分享 收藏
Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments Gueret, Stephanie M.; Thavam, Sasikala; Carbajo, Rodrigo J.; Potowski, Marco; Larsson, Niklas; Dahl, Goran; Dellsen, Anita; Grossmann, Tom N.; Plowright, Alleyn T.; Valeur, Eric; Lemurell, Malin; Waldmann, Herbert 分享 收藏
分享 收藏
Rethinking drug design in the artificial intelligence era 人工智能时代的药物设计再思考 Schneider, Petra; Walters, W. Patrick; Plowright, Alleyn T.; Sieroka, Norman; Listgarten, Jennifer; Goodnow, Robert A., Jr.; Fisher, Jasmin; Jansen, Johanna M.; Duca, Jose S.; Rush, Thomas S.; Zentgraf, Matthias; Hill, John Edward; Krutoholow, Elizabeth; Kohler, Matthias; Blaney, Jeff; Funatsu, Kimito; Luebkemann, Chris; Schneider, Gisbert 分享 收藏
Discovery of Retinoic Acid Receptor Agonists as Proliferators of Cardiac Progenitor Cells Through a Phenotypic Screening Approach Drowley, Lauren; McPheat, Jane; Nordqvist, Anneli; Peel, Samantha; Karlsson, Ulla; Martinsson, Sofia; Mullers, Erik; Dellsen, Anita; Knight, Sinead; Barrett, Ian; Sanchez, Jose; Magnusson, Bjorn; Greber, Boris; Wang, Qing-Dong; Plowright, Alleyn T. 分享 收藏
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway Mills, Richard J.; Parker, Benjamin L.; Quaife-Ryan, Gregory A.; Voges, Holly K.; Needham, Elise J.; Bornot, Aurelie; Ding, Mei; Andersson, Henrik; Polla, Magnus; Elliott, David A.; Drowley, Lauren; Clausen, Maryam; Plowright, Alleyn T.; Barrett, Ian P.; Wang, Qing-Dong; James, David E.; Porrello, Enzo R.; Hudson, James E. 分享 收藏
CRISPR-Knockout Screen Identifies Dmap1 as a Regulator of Chemically Induced Reprogramming and Differentiation of Cardiac Progenitors Yu, Jason S. L.; Palano, Giorgia; Lim, Cindy; Moggio, Aldo; Drowley, Lauren; Plowright, Alleyn T.; Bohlooly-Y, Mohammad; Rosen, Barry S.; Hansson, Emil M.; Wang, Qing-Dong; Yusa, Kosuke 分享 收藏
Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease Pettersen, Daniel; Broddefalk, Johan; Emtenas, Hans; Hayes, Martin A.; Lemurell, Malin; Swanson, Marianne; Ulander, Johan; Whatling, Carl; Amilon, Carl; Ericsson, Hans; Eriksson, Annika Westin; Granberg, Kenneth; Plowright, Alleyn T.; Shamovsky, Igor; Dellsen, Anita; Sundqvist, Monica; Nagard, Mats; Lindstedt, Eva-Lotte 分享 收藏
Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors Laengle, Daniel; Werner, Tessa R.; Wesseler, Fabian; Reckzeh, Elena; Schaumann, Niklas; Drowley, Lauren; Polla, Magnus; Plowright, Alleyn T.; Hirt, Marc N.; Eschenhagen, Thomas; Schade, Dennis 分享 收藏
High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets 用于人iPSC衍生的心肌细胞增殖的高含量表型分析将L型钙通道确定为靶标 Woo, Laura A.; Tkachenko, Svyatoslav; Ding, Mei; Plowright, Alleyn T.; Engkvist, Ola; Andersson, Henrik; Drowley, Lauren; Barrett, Ian; Firth, Mike; Akerblad, Peter; Wolf, Matthew J.; Bekiranov, Stefan; Brautigan, David L.; Wang, Qing-Dong; Saucerman, Jeffrey J. 分享 收藏
分享 收藏
Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1 Durek, Thomas; Cromm, Philipp M.; White, Andrew M.; Schroeder, Christina I.; Kaas, Quentin; Weidmann, Joachim; Fuaad, Abdullah Ahmad; Cheneval, Olivier; Harvey, Peta J.; Daly, Norelle L.; Zhou, Yang; Dellsen, Anita; Osterlund, Torben; Larsson, Niklas; Knerr, Laurent; Bauer, Udo; Kessler, Horst; Cai, Minying; Hruby, Victor J.; Plowright, Alleyn T.; Craik, David J. 分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
