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How can gene editing of human pluripotent stem cells help understand the effect of genetics on respiratory diseases? Ocana, Sara Cuevas; Yang, Jin Ye; Aushev, Magomet; Schlossmacher, George; Bear, Christine E.; Hannan, Nicholas R. F.; Perkins, Neil D.; Rossant, Janet; Wong, Amy P.; Gray, Michael A. 分享 收藏
Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity Quach, Henry; Farrell, Spencer; Wu, Ming Jia Michael; Kanagarajah, Kayshani; Leung, Joseph Wai-Hin; Xu, Xiaoqiao; Kallurkar, Prajkta; Turinsky, Andrei L.; Bear, Christine E.; Ratjen, Felix; Kalish, Brian; Goyal, Sidhartha; Moraes, Theo J.; Wong, Amy P. 分享 收藏
Collagen Tubular Airway-on-Chip for Extended Epithelial Culture and Investigation of Ventilation Dynamics Gao, Wuyang; Kanagarajah, Kayshani R.; Graham, Emma; Soon, Kayla; Veres, Teodor; Moraes, Theo J.; Bear, Christine E.; Veldhuizen, Ruud A.; Wong, Amy P.; Gunther, Axel 分享 收藏
Clinical and functional efficacy of elexacaf tor/tezacaf tor/ivacaf tor in people with cystic fibrosis carrying the N1303K mutation Sadras, Ido; Kerem, Eitan; Livnat, Galit; Sarouk, Ifat; Breuer, Oded; Reiter, Joel; Gileles-Hillel, Alex; Inbar, Ori; Cohen, Michael; Gamliel, Ayelet; Stanleigh, Noemie; Gunawardena, Tarini; Bartlett, Claire; Gonska, Tanja; Moraes, Theo; Eckford, Paul D. W.; Bear, Christine E.; Ratjen, Felix; Kerem, Batsheva; Wilschanski, Michael; Shteinberg, Michal; Cohen-Cymberknoh, Malena 分享 收藏
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Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis Birimberg-Schwartz, Liron; Ip, Wan; Bartlett, Claire; Avolio, Julie; Vonk, Annelotte M.; Gunawardena, Tarini; Du, Kai; Esmaeili, Mohsen; Beekman, Jeffrey M.; Rommens, Johanna; Strug, Lisa; Bear, Christine E.; Moraes, Theo J.; Gonska, Tanja 分享 收藏
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Antisense oligonucleotide splicing modulation as a novel Cystic Fibrosis therapeutic approach for the W1282X nonsense mutation Oren, Yifat S.; Avizur-Barchad, Ofra; Ozeri-Galai, Efrat; Elgrabli, Renana; Schirelman, Meital R.; Blinder, Tehilla; Stampfer, Chava D.; Ordan, Merav; Laselva, Onofrio; Cohen-Cymberknoh, Malena; Kerem, Eitan; Bear, Christine E.; Kerem, Batsheva 分享 收藏
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system Lim, Sang Hyun; Snider, Jamie; Birimberg-Schwartz, Liron; Ip, Wan; Serralha, Joana C.; Botelho, Hugo M.; Lopes-Pacheco, Miqueias; Pinto, Madalena C.; Moutaoufik, Mohamed Taha; Zilocchi, Mara; Laselva, Onofrio; Esmaeili, Mohsen; Kotlyar, Max; Lyakisheva, Anna; Tang, Priscilla; Lopez Vazquez, Lucia; Akula, Indira; Aboualizadeh, Farzaneh; Wong, Victoria; Grozavu, Ingrid; Opacak-Bernardi, Teuta; Yao, Zhong; Mendoza, Meg; Babu, Mohan; Jurisica, Igor; Gonska, Tanja; Bear, Christine E.; Amaral, Margarida D.; Stagljar, Igor 分享 收藏
High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids iPSC衍生的人类肠道类器官中CFTR和其他顶端定位蛋白的高通量功能分析 Xia, Sunny; Bozoky, Zoltan; Di Paola, Michelle; Laselva, Onofrio; Ahmadi, Saumel; Jiang, Jia Xin; Pitstick, Amy L.; Jiang, Chong; Rotin, Daniela; Mayhew, Christopher N.; Jones, Nicola L.; Bear, Christine E. 分享 收藏
Generation of functional ciliated cholangiocytes from human pluripotent stem cells Ogawa, Mina; Jiang, Jia-Xin; Xia, Sunny; Yang, Donghe; Ding, Avrilynn; Laselva, Onofrio; Hernandez, Marcela; Cui, Changyi; Higuchi, Yuichiro; Suemizu, Hiroshi; Dorrell, Craig; Grompe, Markus; Bear, Christine E.; Ogawa, Shinichiro 分享 收藏
A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients 用于囊性纤维化患者的iPSC衍生肺祖细胞的高通量治疗测试的新平台 Jiang, Jia Xin; Wellhauser, Leigh; Laselva, Onofrio; Utkina, Irina; Bozoky, Zoltan; Gunawardena, Tarini; Ngan, Zoe; Xia, Sunny; Di Paola, Michelle; Eckford, Paul D. W.; Ratjen, Felix; Moraes, Theo J.; Parkinson, John; Wong, Amy P.; Bear, Christine E. 分享 收藏
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