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ESR1 genomic alterations (GAs) and coexistent putative resistance alterations in comprehensive genomic profiling (CGP) of metastatic breast cancer (MBC) McArthur, Heather; Tukachinsky, Hanna; Schrock, Alexa; Madison, Russell; Holmes, Oliver; Sivakumar, Smruthy; Sokol, Ethan; Graf, Ryon; Quintanilha, Julia; Dougherty, Kali; Pasquina, Lincoln; Oxnard, Geoffrey; Levy, Mia; Winer, Eric 分享 收藏
ESR1 mutations (ESR1mut) in HR(+)HER2(-)patients with metastatic breast cancer (MBC): prevalence along treatment course and predictive value for endocrine therapy (ET) resistance in real-world practice Bhave, Manali; Quintanilha, Julia; Graf, Ryon; Scott, Takara; Tukachinsky, Hanna; Li, Gerald; Schrock, Alexa; Oxnard, Geoffrey; Levy, Mia; Kalinsky, Kevin 分享 收藏
Liquid biopsy-based circulating tumour (ct)DNA analysis of a spectrum of myeloid and lymphoid malignancies yields clinically actionable results Mata, Douglas A.; Lee, Jessica K.; Shanmugam, Vignesh; Marcus, Chelsea B.; Schrock, Alexa B.; Williams, Erik A.; Ritterhouse, Lauren L.; Hickman, Richard A.; Janovitz, Tyler; Patel, Nimesh R.; Kroger, Benjamin R.; Ross, Jeffrey S.; Mirza, Kamran M.; Oxnard, Geoffrey R.; Vergilio, Jo-Anne; Elvin, Julia A.; Benhamida, Jamal K.; Decker, Brennan; Xu, Mina L. 分享 收藏
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Clinical and genomic correlates of plasma circulating tumor DNA (ctDNA) tumor fraction (TF) in patients with advanced NSCLC dall'Olio, F. G.; Vasseur, D.; Mamann, A.; Garcia, C. A.; Beshiri, K.; Marinello, A.; Tagliamento, M.; Ghigna, M. R.; Aldea, M.; Planchard, D.; Pasquina, L.; Barlesi, F.; Italiano, A.; Madison, R.; Oxnard, G.; Besse, B. 分享 收藏
Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing Tung, Nadine; Dougherty, Kali Chatham; Gatof, Emily Stern; DeLeonardis, Kim; Hogan, Lauren; Tukachinsky, Hanna; Gornstein, Erica; Oxnard, Geoffrey R.; McGregor, Kimberly; Keller, Rachel B. 分享 收藏
Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling-informed personalized monitoring assay Powles, Thomas; Young, Amanda; Nimeiri, Halla; Madison, Russell W.; Fine, Alexander; Zollinger, Daniel R.; Huang, Yanmei; Xu, Chang; Gjoerup, Ole V.; Aushev, Vasily N.; Wu, Hsin-Ta; Aleshin, Alexey; Carter, Corey; Davarpanah, Nicole; Degaonkar, Viraj; Gupta, Pratyush; Mariathasan, Sanjeev; Schleifman, Erica; Assaf, Zoe June; Oxnard, Geoffrey; Hegde, Priti S. 分享 收藏
A longitudinal circulating tumor DNA-based model associated with survival in metastatic non-small-cell lung cancer 基于循环肿瘤DNA的纵向模型与转移性非小细胞肺癌的生存相关 Assaf, Zoe June F.; Zou, Wei; Fine, Alexander D.; Socinski, Mark A.; Young, Amanda; Lipson, Doron; Freidin, Jonathan F.; Kennedy, Mark; Polisecki, Eliana; Nishio, Makoto; Fabrizio, David; Oxnard, Geoffrey R.; Cummings, Craig; Rode, Anja; Reck, Martin; Patil, Namrata S.; Lee, Mark; Shames, David S.; Schulze, Katja 分享 收藏
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Genomic landscape of 891 RET fusions detected across diverse solid tumor types Parimi, Vamsi; Tolba, Khaled; Danziger, Natalie; Kuang, Zheng; Sun, Daokun; Lin, Douglas I.; Hiemenz, Matthew C.; Schrock, Alexa B.; Ross, Jeffrey S.; Oxnard, Geoffrey R.; Huang, Richard S. P. 分享 收藏
Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis Huang, Richard S. P.; Carbone, David P.; Li, Gerald; Schrock, Alexa; Graf, Ryon P.; Zhang, Liangliang; Murugesan, Karthikeyan; Ross, Jeffrey S.; Tolba, Khaled; Sands, Jacob; Oxnard, Geoffrey R.; Spigel, David 分享 收藏
Prognostic value of plasma circulating tumor DNA fraction across four common cancer types: a real-world outcomes study Reichert, Z. R.; Morgan, T. M.; Li, G.; Castellanos, E.; Snow, T.; Dall'Olio, F. G.; Madison, R. W.; Fine, A. D.; Oxnard, G. R.; Graf, R. P.; Stover, D. G. 分享 收藏
Early circulating tumor DNA dynamics as a pan-tumor biomarker for long-term clinical outcome in patients treated with durvalumab and tremelimumab Kansara, Maya; Bhardwaj, Neeru; Thavaneswaran, Subotheni; Xu, Chang; Lee, Jessica K.; Chang, Lo-Bin; Madison, Russell W.; Lin, Frank; Hsu, Eugene; Patel, Vipul Kumar; Aleshin, Alexey; Oxnard, Geoffrey R.; Simes, John; Nimeiri, Halla; Thomas, David M. 分享 收藏
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors KRAS改变癌症的全面泛癌症基因组景观和实体瘤的现实世界结果 Lee, Jessica K.; Sivakumar, Smruthy; Schrock, Alexa B.; Madison, Russell; Fabrizio, David; Gjoerup, Ole; Ross, Jeffrey S.; Frampton, Garrett M.; Napalkov, Pavel; Montesion, Meagan; Schutzman, Jennifer L.; Ye, Xin; Hegde, Priti S.; Nagasaka, Misako; Oxnard, Geoffrey R.; Sokol, Ethan S.; Ou, Sai-Hong Ignatius; Shi, Zhen 分享 收藏
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer Sivakumar, Smruthy; Jin, Dexter X.; Tukachinsky, Hanna; Murugesan, Karthikeyan; McGregor, Kimberly; Danziger, Natalie; Pavlick, Dean; Gjoerup, Ole; Ross, Jeffrey S.; Harmon, Robert; Chung, Jon; Decker, Brennan; Dennis, Lucas; Frampton, Garrett M.; Molinero, Luciana; Oesterreich, Steffi; Venstrom, Jeffrey M.; Oxnard, Geoffrey R.; Hegde, Priti S.; Sokol, Ethan S. 分享 收藏
Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma Margolis, Matthew; Janovitz, Tyler; Laird, Jason; Mata, Douglas A.; Montesion, Meagan; Lee, Jessica K.; Madison, Russell W.; Schrock, Alexa B.; Tukachinsky, Hanna; Allen, Justin M.; Erlich, Rachel; Hiemenz, Matthew C.; Huang, Richard S. P.; Elvin, Julia; Vergilio, Jo-Anne; Lin, Douglas, I; Ross, Jeffrey; Oxnard, Geoffrey; Decker, Brennan 分享 收藏
Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors Kobayashi, Yoshihisa; Oxnard, Geoffrey R.; Cohen, Elizabeth F.; Mahadevan, Navin R.; Alessi, Joao, V; Hung, Yin P.; Bertram, Arrien A.; Heppner, David E.; Ribeiro, Mauricio F.; Sacardo, Karina P.; Saddi, Rodrigo; Macedo, Mariana P.; Blasco, Rafael B.; Li, Jiaqi; Kurppa, Kari J.; Nguyen, Tom; Voligny, Emma; Ananda, Guruprasad; Chiarle, Roberto; Katz, Artur; Tolstorukov, Michael Y.; Sholl, Lynette M.; Janne, Pasi A. 分享 收藏
Complementary Roles for Tissue- and Blood-Based Comprehensive Genomic Profiling for Detection of Actionable Driver Alterations in Advanced NSCLC Schwartzberg, Lee S.; Li, Gerald; Tolba, Khaled; Bourla, Ariel B.; Schulze, Katja; Gadgil, Rujuta; Fine, Alexander; Lofgren, Katherine T.; Graf, Ryon P.; Oxnard, Geoffrey R.; Daniel, Davey 分享 收藏
Brief Report: Safety and Antitumor Activity of Alectinib Plus Atezolizumab From a Phase 1b Study in Advanced ALK-Positive NSCLC Kim, Dong-Wan; Gadgeel, Shirish; Gettinger, Scott N.; Riely, Gregory J.; Oxnard, Geoffrey R.; Mekhail, Tarek; Schmid, Peter; Dowlati, Afshin; Heist, Rebecca S.; Wozniak, Antoinette J.; Singh, Jatinder; Cha, Edward; Spahn, Jessica; Ignatius, Sai-Hong 分享 收藏