Lea‐Yea Chuang - Publications, H-index & Citations

Lea‐Yea Chuang

Kaohsiung Medical University

31H指数

114论文数

2.9K被引数

收录论文 59

发表时间

Effect of osthole on advanced glycation end products-induced renal tubular hypertrophy and role of klotho in its mechanism of action

PHYTOMEDICINE

IF8.3

2019-02-01

PREAI

Kan, Wei-Chih; Hwang, Jean-Yu; Chuang, Lea-Yea; Guh, Jinn-Yuh; Ye, Yi-Ling; Yang, Yu-Lin; Huang, Jau-Shyang

KMUP-1 attenuates high glucose and transforming growth factor-β1-induced pro-fibrotic proteins in mesangial cells

MOLECULAR MEDICINE REPORTS

IF3.5

2017-04-20

OAAI

Lin, Sheng-Hsuan; Chen, Ing-Jun; Chuang, Chao-Tang; Ho, Wan-Ting; Chuang, Lea-Yea; Guh, Jinn-Yuh

Elucidation of the therapeutic role of mitochondrial biogenesis transducers NRF-1 in the regulation of renal fibrosis

EXPERIMENTAL CELL RESEARCH

IF3.5

2016-11-01

PREAI

Hsieh, Pei-Fang; Liu, Shu-Fen; Hung, Tsung-Jen; Hung, Chien-Ya; Liu, Guo-Zheng; Chuang, Lea-Yea; Chen, Mei-Fen; Wang, Jue-Long; Shi, Ming-Der; Hsu, Chen Hung; Shiue, Yow-Ling; Yang, Yu-Lin

Treatment with cytokine thymic stromal lymphopoietin short hairpin RNA substantially reduces TGF-β1-induced interstitial cellular fibrosis

EXPERIMENTAL CELL RESEARCH

IF3.5

2016-09-01

PREAI

Hsieh, Pei-fang; Liu, Shu-Fen; Hung, Tsung-Jen; Hung, Chien-Ya; Liu, Guo-Zheng; Chuang, Lea-Yea; Chen, Mei-Fen; Wang, Jue-Long; Shi, Ming-Der; Hsu, Chen Hung; Shiue, Yow-Ling; Yang, Yu-Lin

Histone methyltransferase Suv39h1 attenuates high glucose-induced fibronectin and p21WAF1 in mesangial cells 组蛋白甲基转移酶Suv39h1减弱高糖诱导的肾小球系膜细胞纤连蛋白和p21WAF1

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IF2.8

2016-09-01

PREAI

Lin, Sheng-Hsuan; Ho, Wan-Ting; Wang, Yeng-Tseng; Chuang, Chao-Tang; Chuang, Lea-Yea; Guh, Jinn-Yuh

Hypoxia-induced vascular endothelial growth factor secretion by retinal pigment epithelial cells is inhibited by melatonin via decreased accumulation of hypoxia-inducible factors-1α protein

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

IF5.6

2016-08-10

PREAI

Lai, Yu-Hung; Hu, Dan-Ning; Rosen, Richard; Sassoon, Jodi; Chuang, Lea-Yea; Wu, Kwou-Yeung; Wu, Wen-Chuan

A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells

SCIENTIFIC REPORTS

IF3.9

2016-08-09

OAAI

Chiou, Shean-Jaw; Wang, Chan-Chi; Tseng, Yan-Shen; Lee, Yen-Jung; Chen, Shih-Chieh; Chou, Chi-Hsien; Chuang, Lea-Yea; Hong, Yi-Ren; Lu, Chi-Yu; Chiu, Chien-Chih; Chignard, Michel

Arecoline-induced pro-fibrotic proteins in LLC-PK1 cells are dependent on c-Jun N-terminal kinase

TOXICOLOGY

IF4.6

2016-02-01

PREAI

Lin, Sheng-Hsuan; Chiou, Shean-Jaw; Ho, Wan-Ting; Chuang, Chao-Tang; Chuang, Lea-Yea; Guh, Jinn-Yuh

Vitamin D-binding protein is required for the protective effects of vitamin D in renal fibroblasts and is phosphorylated in diabetic rats

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2015-08-01

PREAI

Chou, Chi-Hsien; Chuang, Lea-Yea; Lu, Chi-Yu; Guh, Jinn-Yuh

Cinnamaldehyde and Nitric Oxide Attenuate Advanced Glycation End Products-Induced the JAK/STAT Signaling in Human Renal Tubular Cells

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2015-04-10

PREAI

Huang, Jau-Shyang; Lee, Ying-Ho; Chuang, Lea-Yea; Guh, Jinn-Yuh; Hwang, Jean-Yu

S100B is required for high glucose-induced pro-fibrotic gene expression and hypertrophy in mesangial cells

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

IF5.8

2014-12-05

OAAI

Chuang, Chao-Tang; Guh, Jinn-Yuh; Lu, Chi-Yu; Chen, Hung-Chun; Chuang, Lea-Yea

Insight into the modified Ibalizumab-human CD4 receptor interactions: using a computational binding free energy approach

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2014-10-24

PREAI

Wang, Yeng-Tseng; Chuang, Lea-Yea

Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2014-06-01

PREAI

Huang, Jau-Shyang; Chuang, Chao-Tang; Liu, Mei-Hsin; Lin, Sheng-Hsuan; Guh, Jinn-Yuh; Chuang, Lea-Yea

Ubiquitin C-terminal hydrolase-L5 is required for high glucose-induced transforming growth factor-β receptor I expression and hypertrophy in mesangial cells

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2013-07-01

PREAI

Ko, Yu-Min; Chang, Chun-Ying; Chiou, Shean-Jaw; Hsu, Fu-Jie; Huang, Jau-Shyang; Yang, Yu-Lin; Guh, Jinn-Yuh; Chuang, Lea-Yea

Interaction between TGF-β and ACE2-Ang-(1-7)-Mas pathway in high glucose-cultured NRK-52E cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2013-02-01

PREAI

Chou, Chi-Hsien; Chuang, Lea-Yea; Lu, Chi-Yu; Guh, Jinn-Yuh

Anti-proliferative effects of cinnamaldehyde on human hepatoma cell lines

FOOD CHEMISTRY

IF9.8

2012-08-01

PREAI

Chuang, Lea-Yea; Guh, Jinn-Yuh; Chao, Louis Kuoping; Lu, Ying-Chen; Hwang, Jean-Yu; Yang, Yu-Lin; Cheng, Tsan-Hwang; Yang, Wan-Yu; Chien, Ying-Jiun; Huang, Jau-Shyang

Advanced glycation end products-mediated hypertrophy is negatively regulated by tetrahydrobiopterin in renal tubular cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2012-05-01

PREAI

Liao, Yi-Chen; Lee, Ying-Ho; Chuang, Lea-Yea; Guh, Jinn-Yuh; Shi, Ming-Der; Huang, Jau-Shyang

The role of IL-7 in renal proximal tubule epithelial cells fibrosis

MOLECULAR IMMUNOLOGY

IF3

2012-02-01

PREAI

Hsieh, Pei-fang; Liu, Shu-Fen; Lee, Tao-Chen; Huang, Jau-Shyang; Yin, Li-Te; Chang, Wen-Teng; Chuang, Lea-Yea; Guh, Jinn-Yuh; Hung, Min-Yuan; Yang, Yu-Lin

Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells

TRANSLATIONAL RESEARCH

IF5.9

2011-10-01

PREAI

Chen, San-Cher; Guh, Jinn-Yuh; Lin, Tai-Du; Chiou, Shean-Jaw; Hwang, Chi-Ching; Ko, Yu-Min; Chuang, Lea-Yea

Protein identification from two-dimensional gel electrophoresis by connecting ZipTip with a home-assembled nanoflow system

MICROCHIMICA ACTA

IF5.3

2010-07-04

PREAI

Feng, Chia-Hsien; Chou, Chi-Hsien; Chuang, Lea-Yea; Lu, Chi-Yu

研究方向