Daniel A. Portnoy - Publications, H-index & Citations

Daniel A. Portnoy

University of California System

91H指数

219论文数

2.7W被引数

收录论文 70

发表时间

Reprogramming Listeria monocytogenes flavin metabolism to improve its therapeutic safety profile and broaden innate T-cell activation 重编程单核细胞增生李斯特菌（Listeria monocytogenes）黄素代谢以改善其治疗安全性并扩大固有T细胞激活

mBio

IF4.7

2025-12-01

PREAI

Chevee, Victoria; Lobanovska, Mariya; Rivera-Lugo, Rafael; Guereca, Leslie; Feng, Ying; Anaya-Sanchez, Andrea; Garcia Castillo, Jesse; Huckins, Austin M.; Lemmens, Edward E.; Rae, Chris S.; Hardy, Jonathan W.; Carrington, Russell; Kotula, Jonathan W.; Portnoy, Daniel A.

Back to Coley: rethinking bacteria as an anticancer agent

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Dupage, Michel; Castillo, Jesse Garcia; Campbell, Timothy; Fernandez, Sebastian; Gonzalez Ventura, Diego; Williams, Jacob E.; Vickery, Jenna; Portnoy, Daniel A.

Methylglyoxal is an antibacterial effector produced by macrophages during infection 甲基乙二醛是巨噬细胞在感染期间产生的一种抗菌效应分子。

Cell Host & Microbe

IF18.7

2025-06-23

OAAI

Andrea Anaya-Sanchez; Samuel B. Berry; Scott Espich; Alex Zilinskas; Phuong M. Tran; Carolina Agudelo; Helia Samani; K. Heran Darwin; Daniel A. Portnoy; Sarah A. Stanley

Stress-dependent activation of the Listeria monocytogenes virulence program ensures bacterial resilience during infection 压力依赖性的李斯特菌单核细胞增生氏菌毒力程序的激活确保了细菌在感染期间的韧性。

MBIO

IF4.7

2025-06-11

OAAI

Lobanovska, Mariya; Feng, Ying; Zhang, Jonathan; Williams, Allison H.; Portnoy, Daniel A.

Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy 细菌抗肿瘤免疫疗法有益与有害作用背后的细胞机制

Immunity

IF26.3

2025-06-05

PREAI

Jesse Garcia Castillo; Sebastian Fernandez; Timothy Campbell; Diego Gonzalez Ventura; Jacob Williams; Julia Ybarra; Nicole Flores Hernandez; Elina Wells; Daniel A. Portnoy; Michel DuPage

Temporal and spatial dynamics of Listeria monocytogenes central nervous system infection in mice 单核细胞增生李斯特菌中枢神经系统感染小鼠的时空动态

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-04-18

OAAI

Chevee, Victoria; Hullahalli, Karthik; Dailey, Katherine G.; Guereca, Leslie; Zhang, Chenyu; Waldor, Matthew K.; Portnoy, Daniel A.

The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine

MBIO

IF4.7

2023-10-31

OAAI

Feng, Ying; Chang, Shannon K.; Portnoy, Daniel A.

Deficiency in Galectin-3,-8, and-9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens

PLOS PATHOGENS

IF4.9

2023-06-23

OAAI

Morrison, Huntly M.; Craft, Julia; Rivera-Lugo, Rafael; Johnson, Jeffery R.; Golovkine, Guillaume R.; Bell, Samantha L.; Dodd, Claire E.; Van Dis, Erik; Beatty, Wandy L.; Margolis, Shally R.; Repasy, Teresa; Shaker, Isaac; Lee, Angus Y.; Vance, Russell E.; Stanley, Sarah A.; Watson, Robert O.; Krogan, Nevan J.; Portnoy, Daniel A.; Penn, Bennett H.; Cox, Jeffery S.

Depletion of Polymorphonuclear Myeloid-Derived Suppressor Cells Increases Efficacy of Listeria monocytogenes Cancer Vaccine

JOURNAL OF IMMUNOLOGY

IF3.4

2023-05-01

OAAI

Williams, Jacob E.; Castillo, Jesse Garcia; Fernandez, Sebastian; Portnoy, Daniel A.; DuPage, Michel

Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes

MBIO

IF4.7

2023-02-28

OAAI

Rivera-Lugo, Rafael; Huang, Shuo; Lee, Frank; Meheust, Raphael; Iavarone, Anthony T.; Sidebottom, Ashley M.; Oldfield, Eric; Portnoy, Daniel A.; Light, Samuel H.

RibU is an essential determinant of Listeria pathogenesis that mediates acquisition of FMN and FAD during intracellular growth

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-03-22

OAAI

Rivera-Lugo, Rafael; Light, Samuel H.; Garelis, Nicholas E.; Portnoy, Daniel A.

Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes

PLOS PATHOGENS

IF4.9

2021-08-18

OAAI

Anaya-Sanchez, Andrea; Feng, Ying; Berude, John C.; Portnoy, Daniel A.

Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

ELIFE

IF0

2021-06-21

OAAI

Ji, Daisy X.; Witt, Kristen C.; Kotov, Dmitri, I; Margolis, Shally R.; Louie, Alexander; Chevee, Victoria; Chen, Katherine J.; Gaidt, Moritz M.; Dhaliwal, Harmandeep S.; Lee, Angus Y.; Nishimura, Stephen L.; Zamboni, Dario S.; Kramnik, Igor; Portnoy, Daniel A.; Darwin, K. Heran; Vance, Russell E.

Secondary structure of the mRNA encoding listeriolysin O is essential to establish the replicative niche of L. monocytogenes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-09-02

OAAI

Peterson, Bret N.; Portman, Jonathan L.; Feng, Ying; Wang, Jeffrey; Portnoy, Daniel A.

(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes (p)ppGpp和c-di-amp稳态受单核细胞增生李斯特菌CbpB控制

MBIO

IF4.7

2020-08-25

OAAI

Peterson, Bret N.; Young, Megan K. M.; Luo, Shukun; Wang, Jeffrey; Whiteley, Aaron T.; Woodward, Joshua J.; Tong, Liang; Wang, Jue D.; Portnoy, Daniel A.

TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confinedListeria monocytogenes

PLOS PATHOGENS

IF4.9

2020-07-07

OAAI

Nguyen, Brittney N.; Chavez-Arroyo, Alfredo; Cheng, Mandy I.; Krasilnikov, Maria; Louie, Alexander; Portnoy, Daniel A.

An Inducible Cre-lox System to Analyze the Role of LLO in Listeria monocytogenes Pathogenesis

TOXINS

IF4

2020-01-07

OAAI

Nguyen, Brittney N.; Portnoy, Daniel A.

A Multiorgan Trafficking Circuit Provides Purifying Selection of Listeria monocytogenes Virulence Genes

MBIO

IF4.7

2019-12-24

OAAI

Louie, Alexander; Zhang, Ting; Becattini, Simone; Waldor, Matthew K.; Portnoy, Daniel A.

Extracellular electron transfer powers flavinylated extracellular reductases in Gram-positive bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-12-09

OAAI

Light, Samuel H.; Meheust, Raphael; Ferrell, Jessica L.; Cho, Jooyoung; Deng, David; Agostoni, Marco; Iavarone, Anthony T.; Banfield, Jillian F.; D'Orazio, Sarah E. F.; Portnoy, Daniel A.

Recombinant Listeria promotes tumor rejection by CD8+ T cell-dependent remodeling of the tumor microenvironment 重组李斯特菌通过CD8 T细胞依赖性肿瘤微环境重塑促进肿瘤排斥反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-07-23

OAAI

Deng, Weiwen; Lira, Victor; Hudson, Thomas E.; Lemmens, Edward E.; Hanson, William G.; Flores, Ruben; Barajas, Gonzalo; Katibah, George E.; Desbien, Anthony L.; Lauer, Peter; Leong, Meredith L.; Portnoy, Daniel A.; Dubensky, Thomas W., Jr.

研究方向